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Ray Prudo

Director at Akari Therapeutics
Board

About Ray Prudo, M.D.

Independent non-executive director at Akari Therapeutics (AKTX). Age 80; medical degree (MBBS, University of London) and FRCP(C) from the Royal College of Physicians and Surgeons of Canada . Served as Executive Chairman (Sep 2015–Dec 2022), then Chairman of the Board (Jan 1, 2023–Nov 14, 2024), and currently director since Nov 14, 2024 . Attended the 2024 Annual General Meeting in person .

Past Roles

OrganizationRoleTenureCommittees/Impact
Akari Therapeutics, PlcExecutive ChairmanSep 2015–Dec 2022Led company; transitioned governance to non-executive chair in 2023 .
Akari Therapeutics, PlcChairman of the BoardJan 1, 2023–Nov 14, 2024Oversaw board; paid $100,000 annual retainer .
Akari Therapeutics, PlcDirector (Class C)Nov 14, 2024–presentMember, Nominating & Corporate Governance Committee .

External Roles

OrganizationRoleTenureNotes
The Doctors’ Laboratory (TDL)Co-founder; past CEO & ChairmanSince 2002 (chair); historical leadershipTDL is a subsidiary of Sonic Healthcare Limited (ASX: SHL.AX) .
Health Services Laboratories (HSL)DirectorSince 2015HSL is a subsidiary of Sonic Healthcare Limited .
CIS Healthcare LimitedDirectorCurrentPrivately-held UK healthcare company .

Board Governance

  • Current status: Independent director; Board determined Dr. Prudo meets Nasdaq independence standards .
  • Committee assignments: Member of Nominating & Corporate Governance Committee; committee chaired by Robert Bazemore, members include Hoyoung Huh and Ray Prudo .
  • Attendance: Four full board meetings in FY2024; all directors attended ≥75% of board and committee meetings .
  • AGM participation: Attended the 2024 AGM .
  • Board structure and classes: Prudo is Class C director; class terms defined in Articles (A: 1-year; B: 2-year; C: 3-year) .

Fixed Compensation

YearCash Retainer ($)Notes
2023100,000As Chairman of the Board .
202493,059As non-employee director following Nov 14, 2024 transition .
2025 (estimate)45,570Estimated director fees reflecting role change .
  • Non-employee director fee schedule (2024): Board member $41,305; Committee member—Audit $7,875; Compensation $5,570; Nominating & Corporate Governance $5,570; Chair—Audit $18,375; Chair—Compensation $11,139; Chair—N&CG $11,139 .

Performance Compensation

YearOption Awards ($)Grant MechanicsVesting Schedule
202313,000Annual non-employee director option grant policy .Typically vests in full at next AGM; 10-year term; accelerates on change-of-control .
202410,853Annual/assumed option grants context (including Peak Bio assumed awards for others; Prudo held 10,000,000 options) .Standard director vesting and terms as above .
2025 (conditional)N/A cash value not statedOne-time grant of 225,000 ADS options (450,000,000 ordinary shares) to each of specified directors incl. Prudo on Mar 20, 2025, subject to shareholder approval and share pool increase .25% vested on Mar 20, 2025; 25% on Dec 31, 2025; remaining 50% monthly over next 24 months .
  • Director equity policy: Typical annual grant equals options over 5,000,000 ordinary shares (10,000,000 for non-executive chairman); vests at next AGM; 10-year term; change-of-control acceleration; no performance metrics for non-executive directors .

Other Directorships & Interlocks

CompanyTypeConnection to AKTXPotential Conflict Indicator
The Doctors’ Laboratory (TDL)Subsidiary of Sonic HealthcareAKTX leases London office space from TDL ($0.1m + VAT per year in 2023 and 2024) and purchased lab/testing/admin services ($0.1m per year); payables < $0.1m at 12/31/2024 .Related-party transactions due to Prudo’s leadership role at TDL; oversight by audit committee per policy .
Health Services Laboratories (HSL)Subsidiary of Sonic HealthcareNo direct transaction disclosed with AKTX .None stated .

Expertise & Qualifications

  • Medical training: MBBS, University of London; FRCP(C) .
  • Healthcare operations: Founder/leader of TDL and director at HSL; experience in healthcare services and laboratory operations .
  • Board qualifications: Independent director; member of N&CG committee .

Equity Ownership

Metric12/31/20245/15/202510/31/2025
Ordinary Shares owned (direct + affiliates)4,916,600,800 6,003,452,? See breakdown6,248,396,800
Direct ordinary shares (Prudo individually)4,077,124,600 5,163,920,600 5,163,920,600
Options exercisable within 60 days20,000,000 (10,000,000 vested) 20,056,250 245,000,000
Warrants (subject to 9.99% cap; excluded from % calc)1,932,587,500 Excludes up to 3,710,799,500 Excludes up to 3,710,799,500
RPC Pharma Limited (affiliated) shares800,766,600 800,766,600 800,766,600
Praxis Trustees Limited shares38,709,600 38,709,600 38,709,600
Beneficial ownership (%)N/AN/A8.7% of ordinary shares outstanding

Notes:

  • ADS ratio: 1 ADS = 2,000 ordinary shares .
  • Ownership percentages are computed per SEC rules, including options/warrants exercisable within 60 days for the individual holder .
  • As of Oct 31, 2025, % based on 71,479,461,523 ordinary shares outstanding .

Fixed vs Variable Pay Mix (2024)

ComponentAmount ($)Nature
Cash fees93,059 Fixed retainer/committee fees
Option awards (grant date fair value)10,853 Time-based equity; non-performance
Total103,912 Predominantly fixed cash

Related-Party Transactions (Conflict Risk)

  • May 2024 convertible notes: Company entered unsecured convertible notes totaling $1.0m with Dr. Prudo and Dr. Samir Patel; $750k repaid in Oct 2024; each converted $125k principal plus interest into ADSs at $1.59; shares issued Apr 30, 2025 .
  • TDL arrangements: AKTX leased office space from TDL ($0.1m + VAT per year in 2023 and 2024) and procured lab services ($0.1m per year); payables < $0.1m at Dec 31, 2024 .
  • Governance controls: Audit committee (all independent) reviews and approves related-party transactions; directors must recuse from decisions affecting personal interests; conflicts handled per Code of Business Conduct and committee charters .

Equity Ownership Risk Controls

  • Insider trading policy prohibits short sales, options transactions, pledging/margin use, collars/hedging except under limited circumstances with prior approval .
  • No specific director stock ownership guidelines disclosed; non-executive directors may elect to receive annual cash payments in fully vested shares, although none elected this in 2024 .

Compensation Structure Analysis

  • Shift from chair to director: Cash fees decreased from $100,000 (2023 chair) to $93,059 (2024 director) and are estimated at $45,570 in 2025, reflecting role change rather than pay inflation .
  • Non-performance equity: Director options are time-based, vest at next AGM, with change-of-control acceleration; no performance metrics or clawbacks for non-executive director awards—maintains independence but weakens pay-for-performance alignment .
  • One-time 2025 director options: Conditional awards intended to recognize strategic reprioritization post-transaction; vesting staged over 2025–2027; contingent on share pool increase and shareholder approval, mitigating dilution concerns through governance process .

Governance Assessment

  • Strengths:

    • Independent status affirmed; active role on N&CG; ≥75% attendance; AGM participation signals engagement .
    • Clear related-party review procedures; director recusal requirements and audit committee oversight .
    • Non-executive equity grants structured with vesting and change-of-control acceleration; no bonus participation preserves independence .
  • Watch items / RED FLAGS:

    • Related-party exposure via TDL office lease and services while Prudo holds leadership roles at TDL—ongoing transactions (~$0.1m/year) warrant continued independence safeguards .
    • Convertible note financing (May 2024) with director participants (including Prudo)—acceptable bridge financing but underscores need for full board/audit oversight and disclosure compliance .
    • Significant beneficial ownership (8.7%) and warrants subject to 9.99% cap—concentration risk; ensure voting/transaction recusal per Articles/Code .
  • Overall: Governance framework and independence affirmations are robust, but recurring related-party transactions with TDL and prior financing relationships require vigilant audit oversight and strict adherence to recusal/conflict policies to maintain investor confidence .