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Daphne Quimi

Director at Amylyx Pharmaceuticals
Board

About Daphne Quimi

Daphne Quimi, 59, has served as an independent director at Amylyx Pharmaceuticals since June 2021 and is a Class III director with a term expiring at the 2027 annual meeting. She is a seasoned biopharma finance executive, formerly CFO of Amicus Therapeutics (2019–Aug 2023) and advisor to the CFO until March 2024, with prior roles at Bristol-Myers Squibb. She holds a B.S. in Accountancy from Monmouth University and an MBA from NYU Stern .

Past Roles

OrganizationRoleTenureCommittees/Impact
Amicus Therapeutics, Inc.Chief Financial OfficerJan 2019 – Aug 2023Led rare disease commercialization and global finance operations
Amicus Therapeutics, Inc.Advisor to the CFOAug 2023 – Mar 2024Transitional advisory capacity
Bristol-Myers Squibb CompanyDirector of Consolidations & External Reporting2005 – 2007External reporting leadership

External Roles

OrganizationRoleSinceNotes
Century Therapeutics, Inc. (Nasdaq: IPSC)DirectorOct 2022Public company directorship
Chiesi Farmaceutici S.p.A.DirectorJan 2025Private pharma board role

Board Governance

  • Independence: Board determined all directors except the Co-CEOs are independent under Nasdaq and SEC rules; Quimi is independent .
  • Committee roles: Audit Committee Chair; Compensation Committee member. Audit members are independent; Quimi is designated the Audit Committee Financial Expert. Audit met 5 times in 2024; Compensation met 7 times in 2024 .
  • Attendance: The full board met 16 times in 2024; each director attended at least 75% of board and applicable committee meetings. In 2023, the board met 13 times with ≥75% attendance by each director .
  • Governance policies: Anti-hedging and anti-pledging policy; Compensation Recovery (clawback) policy adopted Oct 2, 2023 .

Fixed Compensation

MetricFY 2022FY 2024Notes
Board/Committee Cash Fees ($)$58,589 $72,500 FY 2024 aligns with policy: Board member $45,000, Audit Chair $20,000, Compensation member $7,500

Cash retainers are set by the non-employee director compensation policy adopted and amended in 2023; Quimi’s FY 2024 fees reflect her roles as Audit Chair and Compensation member .

Performance Compensation

MetricFY 2022FY 2024Policy/Structure
Option Awards (Grant-Date Fair Value, $)$293,500 $27,704 Annual equity grant: lesser of $285,000 FV or 25,000 options; Initial grant: lesser of $570,000 FV or 50,000 options
Options Held (Exercisable, #)38,830 115,351 Year-end holdings (exercisable)
Options Held (Unexercisable, #)69,670 35,134 Year-end holdings (unexercisable)

Director equity is granted as stock options; vesting typically completes within one year for annual grants and pro-rates per policy. No RSUs for non-employee directors were outstanding at FY 2024 year-end .

Other Directorships & Interlocks

CompanyRelationship to AMLXPotential Interlock/Conflict Notes
Century Therapeutics, Inc. (IPSC) No related-party transactions disclosedMonitor for future collaborations/transactions given biopharma domain overlap; none reported since Jan 1, 2023
Chiesi Farmaceutici S.p.A. No related-party transactions disclosedPrivate company role; watch for supplier/customer relationships; none reported

Expertise & Qualifications

  • Financial expert: Audit Committee Financial Expert designation under SEC rules .
  • Strategic finance and commercialization experience in rare diseases; senior roles at Amicus and Bristol-Myers Squibb .
  • Formal education: B.S. in Accountancy; MBA (NYU Stern) .

Equity Ownership

MetricAs of Apr 11, 2023As of Apr 11, 2025
Beneficial Ownership (Total Shares)66,275 (options exercisable within 60 days) 153,796 (5,000 common + 148,796 options exercisable within 60 days)
Ownership % of Outstanding<1% (company disclosure) <1% (company disclosure)
Anti-Hedging/Pledging CompliancePolicy prohibits hedging/pledging Policy prohibits hedging/pledging

Governance Assessment

  • Strengths

    • Independent director with deep finance expertise; Audit Committee Chair and SEC-designated financial expert support robust financial oversight .
    • Solid engagement: frequent committee meetings (Audit 5x; Compensation 7x in 2024) and ≥75% attendance; indicates active oversight .
    • Alignment policies: Anti-hedging/pledging and clawback adopted Oct 2023 enhance investor protection .
    • Ownership: Increased in-the-money/exercisable options and common share holding by 2025; supports skin-in-the-game (albeit <1%) .
  • Watch items

    • Multi-board commitments (Century Therapeutics; Chiesi) could present time-allocation risks; monitor for potential related-party transactions or strategic overlaps—none disclosed since Jan 1, 2023 .
    • Director equity is option-heavy; while standard, large variability in grant-date values (2022 vs 2024) merits monitoring for consistency with policy and market alignment .
  • Red flags

    • None disclosed: No related-party transactions above threshold, no legal proceedings adverse to AMLX, and no pledging/hedging activities permitted .

Compensation Committee uses independent consultant Pearl Meyer; committee independence affirmed; no consultant conflicts identified .