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David Keenan, Ph.D.

Executive Vice President, Chief Operating Officer at AMARIN CORP PLC\UKAMARIN CORP PLC\UK
Executive

About David Keenan, Ph.D.

David Keenan, Ph.D., age 58, is Executive Vice President and Chief Operating Officer (COO) of Amarin, appointed effective October 17, 2025; he joined Amarin in May 2022 as Senior Vice President, Technical Operations and was promoted to Executive Vice President with expanded responsibility for European operations in July 2023 . He holds a Ph.D. in Organic Chemistry from Maynooth University, an MBA from Dublin City University, and is a qualified Chartered Director; he has also served as Chair of BioPharmachem Ireland and President of the Irish Affiliate of ISPE . Company operating context relevant to executive incentives: Amarin reported 2024 revenues over $200 million, ended 2024 with $294 million cash and no debt, and highlighted nine consecutive quarters of cash positive or neutral operations, with European launches progressing and regulatory approvals in China and Australia .

Past Roles

OrganizationRoleYearsStrategic impact
Amarin Pharmaceuticals Ireland LimitedSenior Vice President, Technical OperationsMay 2022 – Jul 2023Global responsibility for manufacturing, supply chain, technical operations, and quality
Amarin Corporation plcExecutive Vice President, Technical Operations & President EuropeJul 2023 – Oct 2025Expanded remit to include management of European operations
Amarin Corporation plcExecutive Vice President & Chief Operating OfficerOct 17, 2025 – PresentCOO appointment; no change to compensation at appointment

External Roles

OrganizationRoleYearsNotes
BioPharmachem IrelandChairN/AIndustry leadership role cited in 8-K
ISPE (Irish Affiliate)PresidentN/AProfessional society leadership

Fixed Compensation

MetricAs of Jul 17, 2023As of Oct 17, 2025
Base Salary (€)€450,000 No change at COO appointment
Target bonus %Not disclosedNot disclosed
Actual annual bonusNot disclosedNot disclosed

Notes:

  • Jul 17, 2023 amendment set title to EVP, Technical Operations & President of Europe and salary to €450,000; it also enrolled Keenan in Amarin’s Executive Severance and Change of Control Plan .
  • The Oct 17, 2025 COO appointment explicitly stated no change to compensation as a result of the appointment .

Performance Compensation

Company-level incentive design and outcomes that apply to executive officers under the Management Incentive Compensation Plan:

MetricWeightingTarget (qualitative)Actual achievementWeighted score
Financial (revenue, opex, cash, inventory per 2024 plan)60% Achieve plan targets (specifics not disclosed) 98% achieved 59%
Commercial – EU market access10% (50% of commercial) Plan-consistent access 75% achieved 7.5%
Commercial – defend exclusive payor segments4% (20% of commercial) Defend share 100% achieved 4%
Commercial – regulatory approvals (new markets)2% (10% of commercial) Obtain approvals 100% achieved 2%
Commercial – advance regulatory filings2% (10% of commercial) Advance filings 100% achieved 2%
Commercial – secure product availability2% (10% of commercial) Support launches 100% achieved 2%
Pipeline & Medical – scientific knowledge/conviction in Europe7% (70% of P&M) Advance evidence 133% achieved 9%
Pipeline & Medical – next-step strategic options3% (30% of P&M) Complete evaluations 100% achieved 3%
People & Culture – risk mgmt & cybersecurity4% (40% of P&C) Strengthen programs 100% achieved 4%
People & Culture – employee engagement3% (30% of P&C) Improve survey 133% achieved 4%
People & Culture – talent retention3% (30% of P&C) Voluntary turnover below industry avg 100% achieved 3%
Total corporate goal achievement100%99.5% achieved 99.5%

Design notes:

  • 2024 long-term equity mix increased weighting to 75% stock options and 25% time-based RSUs to align pay with stock performance; CEO retained a separate performance-based option grant; peer group benchmarking and “pay for performance” emphasis affirmed .

Equity Ownership & Alignment

Ownership and awards reported on Form 3 (initial statement of beneficial ownership) upon COO appointment; ADS-to-ordinary share ratio change noted April 11, 2025.

CategoryDetailVesting scheduleExpiration
Direct holdings7,950 ADS held directly N/AN/A
RSU grant (Feb 21, 2023)6,740 ADS-equivalent RSUs1/31/2024, 1/31/2025, 1/31/2026 (equal installments) N/A
RSU grant (Feb 1, 2024)5,800 ADS-equivalent RSUs1/31/2025, 1/31/2026, 1/31/2027 (equal installments) N/A
RSU grant (Jan 10, 2025)7,376 ADS-equivalent RSUs 50% vests on 1st anniversary; remaining vests at 18 months (i.e., 1/10/2026 and 7/10/2026) N/A
Option grant (Jan 10, 2025)33,193 ADS-equivalent options @ $12.40 33% at 1-year; balance ratably over next 8 quarters (quarterly on last day of Apr/Jul/Oct/Jan) 01/10/2035
Option grant (Feb 1, 2024)20,900 ADS-equivalent options @ $24.20 Same 3-year schedule as above 02/01/2034
Option grant (Feb 21, 2023)13,480 ADS-equivalent options @ $36.00 3-year schedule (33% at 1-year; balance over 8 quarters)02/21/2033
Option grant (Jun 1, 2022)5,000 ADS-equivalent options @ $29.00 4-year schedule (25% at 1-year; balance over 12 quarters) 06/01/2032

Ownership alignment and restrictions:

  • Stock ownership guidelines: CEO 3x salary; other executive officers 1x salary; five-year compliance window from appointment .
  • Anti-hedging/anti-pledging policy: Hedging and pledging prohibited without Audit Committee approval; exceptions considered case-by-case .
  • Insider trading policy and clawback: Incentive compensation subject to clawback for restatements/material errors under SEC/Nasdaq-compliant policy adopted Oct 2023; hedging/pledging restrictions reaffirmed .

Reference data:

  • ADS ratio change noted April 11, 2025: 1 ADS represents 20 Ordinary Shares; awards adjusted accordingly .
  • Outstanding shares: 414,186,296 Ordinary Shares as of Feb 28, 2025 (company-wide) .

Employment Terms

TermDetail
Employment agreementOriginal contract of service effective May 1, 2022 for Senior Vice President, Technical Operations
First amendmentJul 17, 2023: Title updated to EVP, Technical Operations & President Europe; salary €450,000; reporting to CEO; enrolled in Executive Severance & Change of Control Plan (Jan 28, 2021), with enhanced severance outside CoC and further enhanced within CoC; severance inclusive of Irish law entitlements and notice period amounts
Second amendmentOct 6, 2025: Title updated to EVP & COO; notice period increased from 3 months to 6 months; Section 16 officer status confirmed
Non-compete / restricted periodEmployment contract defines a “Restricted Period” of six months post-termination and includes potential garden leave (Clause 18)
Broader executive agreement constraintsExecutive employment agreements prohibit competition, employee solicitation, customer diversion, and disclosure of confidential information
Change-of-control mechanicsCompany-wide: double-trigger requirement for severance/accelerated vesting (CoC plus qualifying termination); no single-trigger
ClawbackCompensation recovery policy in place per Dodd-Frank, SEC rules, and Nasdaq standards
Tax gross-upsNo tax gross-ups on perquisites, severance, or change-in-control payments
PerquisitesCompany states it does not provide significant perquisites to executive officers

Compensation Governance Context

  • Say-on-pay approval: Approximately 79.5–80% support at 2024 AGM .
  • Peer group methodology: 2024 peer group (18 companies) and 2025 updated peer group (16 companies) used to align compensation around market 50th percentile .
  • Committee independence and consultants: Remuneration Committee composed of independent directors; engaged Aon then Pearl Meyer in 2024–2025 .

Investment Implications

  • Alignment and upside: Keenan’s equity mix (multi-year RSUs plus sizeable option grants vesting over 3–4 years) ties compensation to stock performance and facilitates retention through staggered vesting; anti-hedging/anti-pledging limits short-term monetization and align long-term interests .
  • Near-term selling pressure: RSU vesting dates in late Jan 2026 and mid-2026 (from 2023–2025 grants) could create scheduled liquidity windows; monitoring Form 4 filings around 1/31/2026 and 7/10/2026 is prudent .
  • Retention risk moderated: The 6-month notice period, 6-month post-termination restricted period, and double-trigger change-of-control economics reduce immediate exit incentives and protect enterprise continuity; enrollment in the Executive Severance Plan provides structured outcomes under various scenarios .
  • Execution capability: Keenan’s operating and quality background, combined with prior leadership across European operations, supports Amarin’s 2024–2025 priorities in EU market access and RoW expansion—areas explicitly embedded in incentive design and corporate goals .