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Daniel Faga

Daniel Faga

President and Chief Executive Officer at ANAPTYSBIOANAPTYSBIO
CEO
Executive
Board

About Daniel Faga

Daniel Faga is President & CEO of AnaptysBio and a Class I director, age 45, serving as Interim CEO from March 21, 2022 through August 2, 2023 and as CEO since August 3, 2023; he joined the Board in November 2021 . He holds a B.S. in Engineering from Cornell University and an MBA in Health Care Management from The Wharton School (University of Pennsylvania), with prior senior roles at Mirati Therapeutics (COO), Spark Therapeutics (Chief Business Officer), Centerview Partners, Merrill Lynch, and PRTM . Pay-versus-performance disclosures show cumulative TSR translating a hypothetical $100 investment to $89 in 2022, $62 in 2023, and $38 in 2024 alongside net losses of $128.7M (2022), $163.6M (2023), and $145.2M (2024), illustrating challenging shareholder returns in his tenure-to-date for a pre-commercial biotech .

Past Roles

OrganizationRoleYearsStrategic Impact
Mirati TherapeuticsChief Operating Officer2020–2021Led corporate strategy, finance, legal and operations
Spark TherapeuticsChief Business Officer2016–2019Led corporate strategy, portfolio planning, BD, program mgmt, corporate comms
Centerview PartnersManaging Director (founding member of healthcare advisory)2009–2016Built healthcare advisory practice; strategic M&A advisory
Merrill LynchHealthcare Investment BankingN/AInvestment banking coverage; transaction execution
PRTMManagement Consultant, Life Sciences PracticeN/AOperations/strategy advisory in life sciences

External Roles

No current public-company board roles disclosed for Mr. Faga in ANAB’s proxy biography .

Fixed Compensation

MetricFY 2023FY 2024
Base Salary ($)640,605 685,448
Target Bonus (% of base)55% 60%
Actual Bonus Paid ($)352,333 308,452 (funded at 75% of target)

Performance Compensation

Long-term incentive awards and vesting terms:

AwardGrant DateShares/UnitsKey Terms
Stock OptionsJan 3, 2024379,620Exercise price $21.19; 10-year term to Jan 2, 2034; 25% vests on Jan 3, 2025, remainder monthly thereafter
RSUsJan 3, 2024138,710Vests in equal annual installments over 4 years beginning Jan 3, 2025
PSUs (Share-Price)Jul 22, 2024160,000Three tranches tied to $50 / $75 / $100 60-trading-day avg share-price hurdles; once achieved, 50% vests 1-year from service vesting commencement (≥ Jul 1, 2025), remaining 50% at 2 years; none achieved by Apr 1, 2025
RSUs (CEO inducement)Mar 21, 2022887,043New-hire RSUs vested in full on Mar 21, 2024

2024 Annual Cash Bonus Plan metrics included milestones across rosnilimab Phase 2 RA/UC execution, ANB032 Phase 2 AD readout, portfolio advancement (ANB033/ANB101), finance (budget/runway/biz dev), and talent/culture. Corporate goals were approved in Dec 2023 and assessed at 75% for funding; category weightings were not disclosed .

Equity Ownership & Alignment

Ownership Detail (as of Apr 1, 2025)AmountNotes
Total Beneficial Ownership (shares)699,219 (2.3%) 2.3% of 30,332,693 shares outstanding
Directly Held Shares436,466 Common stock held directly
Issuable within 60 days (options/RSUs)262,753 Options/RSUs exercisable/vesting within 60 days
Hedging/PledgingProhibited Company Insider Trading Policy bans hedging, margin purchases, and pledging

Ownership guidelines for executives were not disclosed; director guidelines were not discussed for executives.

Employment Terms

ProvisionTerms
Employment AgreementCEO agreement effective Aug 3, 2023; one-time $1.5M transition bonus paid (subject to pro-rata clawback if termination for cause or resignation without good reason before Aug 4, 2025); excise-tax gross-up eligibility ceased Mar 21, 2024
Severance (without cause / good reason)12 months salary continuation; 12 months COBRA premiums; 12 months accelerated vesting of equity awards (except PSUs, of which only 50% of Eligible PSUs vest) upon qualifying termination; release required
Change-in-Control (Plan mechanics)Awards may be assumed/replaced; if not, Board may accelerate vesting; non-employee director awards accelerate at CoC; treatment may vary by award
ClawbackCompany-wide clawback policy applies to incentive compensation and equity awards

Board Governance

ItemDetail
Board ServiceClass I director since Nov 2021
Committee RolesNone (CEO not on audit/comp/nom-gov committees)
IndependenceNot independent due to CEO role
Chair/CEO StructureRoles separated; John Orwin serves as Chairman
Board MeetingsIn 2024, Board held eight meetings; no director attended fewer than 75% of aggregate meetings and committee meetings served

Dual-role implications: As CEO and a director, Mr. Faga is a management director and not independent, though separation of Chairman and CEO mitigates concentration of power and enhances independent oversight .

Director Compensation

Mr. Faga receives no fees or equity for Board service separate from his CEO compensation .

Compensation Peer Group and Governance

  • 2024 peer group for benchmarking included: Allakos, Alector, ALX Oncology Holding, Atara Biotherapeutics, Avidity Biosciences, Crinetics, Celldex, Gossamer Bio, IGM Biosciences, iTeos, Kodiak, Kura, Mersana, NGM, RAPT, Sangamo, Syndax, Xencor .
  • Governance improvements: Removed evergreen share-pool increase in 2024; prohibited option/SAR repricing without stockholder approval; sought additional shares to support talent retention .

Say-on-Pay & Shareholder Feedback

YearApproval
2023~68% approval; investor feedback noted concerns on new-hire grant and 280G gross-up; company ceased excise-tax gross-up eligibility as of Mar 21, 2024
2024~87% approval; ongoing investor engagement disclosed

Risk Indicators & Red Flags

  • Hedging/pledging of company stock prohibited, reducing misalignment risk .
  • Clawback policy applies to incentive comp and equity .
  • Option/SAR repricing prohibited absent stockholder approval .
  • Earlier excise-tax gross-up eligibility was removed in 2024, addressing a shareholder-unfriendly feature .
  • Equity overhang and burn rates disclosed with shareholder authorization sought for incremental shares to manage dilution (2025 proposal for +1,650,000 shares) .

Investment Implications

  • Pay-for-performance alignment improved in 2024: bonus tied to clinical and financial milestones funded at 75% vs 100% in 2023, and introduction of multi-year PSUs with high share-price hurdles ($50/$75/$100) that require sustained performance; none have vested yet—dampening near-term insider selling pressure from PSUs .
  • Vesting exposure: 2024 RSUs and options began vesting in 2025 and continue via annual and monthly schedules, potentially creating periodic selling windows; hedging/pledging bans limit leverage-based dispositions .
  • Retention calculus: Robust severance and equity acceleration (12 months for most equity, partial for PSUs) provide downside protection, but sustained equity upside depends on clinical execution across rosnilimab, ANB032, and early portfolio milestones, with TSR and net income trends highlighting ongoing execution risk typical of pre-commercial biotech .
  • Governance strengths include separation of Chair/CEO, independent committees, and enhanced equity plan governance post-2024; prior concerns on excise-tax gross-ups addressed, and Say-on-Pay support increased to 87% in 2024, signaling improved investor acceptance of the compensation framework .