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John Orwin

Chairman of the Board at ANAPTYSBIOANAPTYSBIO
Board

About John Orwin

John Orwin (age 63) is Chairman of the Board and a Class II director at AnaptysBio (ANAB), serving since September 2023. He is an independent director under Nasdaq rules, with prior CEO and extensive board experience across biopharma. He holds a B.A. in Economics from Rutgers University and an MBA from New York University .

Past Roles

OrganizationRoleTenureCommittees/Impact
Atreca, Inc.President & Chief Executive OfficerApr 2018 – Jun 2024Led public biotech; operational and strategic leadership
Seagen, Inc.DirectorJan 2014 – Dec 2023Board service until acquisition by Pfizer; oncology leadership exposure
Array BioPharma, Inc.DirectorNov 2012 – Jul 2019Board service; small-molecule oncology

External Roles

OrganizationRoleTenurePublic/PrivateCommittees/Notes
Samsara BioCapital, L.P.Venture PartnerSince 2024Private VCInvestment oversight
Nested Therapeutics, Inc.Chair of BoardCurrentPrivateBoard leadership
Ambrosia Biosciences, Inc.DirectorCurrentPrivateBoard service
Agni Bio, Inc.Executive ChairmanCurrentPrivateExecutive chair role
CARGO Therapeutics, Inc.DirectorSince Aug 2022PublicBoard service (cell therapy)
Travere Therapeutics, Inc.DirectorSince Mar 2017PublicBoard service (rare disease)

Board Governance

  • Role: Non-executive Chairman; CEO and Chair roles are separated, enhancing oversight and accountability .
  • Independence: Board determined Orwin to be independent alongside 7 other non-employee directors .
  • Committee Assignments: Member, Nominating & Corporate Governance Committee (Chair: Hollings Renton) .
  • Attendance: In 2024, the Board met 8 times; committees met 4/4/3 (Audit/Comp/NomGov). No director attended <75% of meetings; nine directors attended the 2024 annual meeting. Independent directors meet separately on a regular basis .
  • Risk Oversight: Board oversees strategy and risk; audit committee covers cybersecurity and controls; compensation committee reviews incentive risk; nominating committee manages governance risk .

Fixed Compensation

2024 non-employee director cash components for John Orwin:

ComponentAmount (USD)
Base Director Retainer$40,000
Non-Executive Chair Fee$35,000
Nominating & Governance Committee Member Fee$5,000
Total Cash Fees Earned$80,000

Notes:

  • Director cash fees are paid quarterly, pro-rated; ANAB increased certain chair/member fees in 2024 versus 2023 to align with peer practices .

Performance Compensation

Director equity grants are time-based, not tied to operating performance metrics:

  • 2024 Equity Awards (Grant-Date Fair Value): Options $248,918; Stock Awards (RSUs) $127,776; Total $376,694 .
  • Standard annual grants: stock options for 16,510 shares vest monthly over one year; 6,030 RSUs vest at the next annual meeting, subject to service .
  • Change-of-control: All equity awards held by non-employee directors accelerate fully upon a change in control .

Other Directorships & Interlocks

CompanyTypePotential Interlock/Conflict Consideration
CARGO Therapeutics (CRGX)Public biotechGeneral sector overlap; no ANAB related-party transactions disclosed
Travere Therapeutics (TVTX)Public biotechSector overlap; no ANAB related-party transactions disclosed
Seagen (prior), Array BioPharma (prior)Public biotech (prior)Historical roles; no current ANAB transactions
Samsara BioCapital (venture partner), Nested, Ambrosia, Agni BioPrivateInvestment/board roles; ANAB policy requires audit committee review of any related-party transactions; none reported

Expertise & Qualifications

  • Executive leadership as CEO (Atreca) and executive chair (Agni Bio); broad biopharma operating experience .
  • Board leadership across oncology and immunology; multi-company governance exposure .
  • Education: B.A. Economics (Rutgers); MBA (NYU) .

Equity Ownership

HolderShares Beneficially Owned (#)% of OutstandingBreakdown
John Orwin34,548 <1% 3,335 shares held directly; 31,213 options exercisable within 60 days
Outstanding Director Awards (as of 12/31/24)Options: 30,421; RSUs: 8,630N/AAs disclosed for Orwin’s outstanding awards

Additional alignment and safeguards:

  • Hedging and pledging of company stock are prohibited for directors under ANAB’s Insider Trading Policy .
  • Equity grant timing is standardized to avoid opportunistic timing .

Governance Assessment

  • Strengths
    • Independent Chairman with robust sector expertise; clear separation from management strengthens oversight .
    • High attendance and regular independent executive sessions support board effectiveness .
    • Director equity is time-based with CoC acceleration; aligns with market norms while avoiding short-term performance gaming .
  • Watch Items
    • Multiple external boards and VC affiliation (Samsara BioCapital) increase time commitments; however, ANAB reports no related-party transactions above thresholds and maintains a formal review policy .
    • Equity-heavy director compensation (options + RSUs totaling $376,694 grant-date fair value in 2024) can create sensitivity to share price volatility; mitigated by prohibition on hedging/pledging and standardized grant timing .
  • Signals
    • Board updated director fee structure in 2024 to remain competitive, modestly increasing chair/member fees—indicative of responsive governance practices .
    • Say-on-Pay approval for executives at ~87% in 2024 suggests overall investor comfort with compensation governance; though focused on NEOs, it reflects broader confidence in board oversight .

Board Governance (Details)

AttributeDetails
Board ChairJohn Orwin (non-executive)
Independence8 of 9 directors independent; Orwin included
CommitteesOrwin: Nominating & Corporate Governance (member)
Meetings & Attendance (2024)Board: 8; Audit: 4; Compensation: 4; Nom/Gov: 3; all directors ≥75% attendance
Executive SessionsIndependent directors meet separately on a regular basis
Risk OversightBoard; Audit covers cybersecurity and ICFR; Comp reviews incentive risk; Nom/Gov manages governance risk

Director Compensation (2024) – Mix and Structure

CategoryCashEquityTotal
John Orwin$80,000 [retainer + chair + committee member] Options $248,918; RSUs $127,776 $456,694
  • Cash fee components explicitly match policy schedules: $40,000 retainer + $35,000 non-executive chair + $5,000 nom/gov member .
  • Equity grants follow time-based vesting; non-employee director awards accelerate upon change-in-control .

Related Party & Conflicts

  • No related-party transactions (>$120k or >1% of average total assets) reported from Jan 1, 2023 to proxy date; transactions require audit committee approval per policy .
  • Insider Trading Policy prohibits hedging, monetization, margin purchases, and pledging, reducing misalignment risk .

Say-on-Pay & Shareholder Feedback (Context)

  • 2024 Say-on-Pay approval approximately 87% for executive compensation; company engages with shareholders on compensation design and maintains annual advisory votes .

Compensation Peer Group (Context)

  • Peer group updated in 2023 for 2024 decisions; used for competitive positioning of compensation elements (primarily for executives) .

RED FLAGS

  • None disclosed: no hedging/pledging, no related-party dealings, no attendance issues .
  • Potential time-commitment risk due to multiple concurrent board/VC roles; monitor for future related-party disclosures as governance policies require review .