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Michael Overdorf

EVP & Chief Business Officer at Annexon
Executive

About Michael Overdorf

Michael Overdorf, age 55 as of April 8, 2025, serves as Executive Vice President and Chief Business Officer at Annexon, Inc., a role he has held since July 2020 after nearly two decades at Eli Lilly & Company in corporate business development and strategy, commercial leadership, and global biologics program leadership. He holds a B.A. in Economics from Wabash College and an M.B.A. from Harvard Business School, and is an adjunct lecturer in Medicine in the Division of Clinical Pharmacology at the Indiana University School of Medicine . Annexon’s pay-versus-performance disclosures track shareholder return alongside executive compensation, but Overdorf was not a named executive officer (NEO) in 2024 and 2025; his most detailed compensation disclosure is in the 2023 proxy for fiscal 2022 .

Past Roles

OrganizationRoleYearsStrategic Impact
Eli Lilly & CompanyVarious executive leadership roles including Corporate Business Development & Corporate Strategy; Global Biologics Platform Team Leader; COO, Bio-Medicines BU; CMO UK; GM Czech & Slovak Republics2001–2020Led development and execution of Lilly’s global strategy; led two Phase 3 biologics programs targeting autoimmune diseases; multiple commercial leadership roles across geographies

External Roles

OrganizationRoleYearsStrategic Impact
Indiana University School of Medicine (Division of Clinical Pharmacology)Adjunct Lecturer in MedicineOngoing (as disclosed)Academic contribution to clinical pharmacology; enhances industry-academic linkage

Fixed Compensation

Metric20212022
Base Salary ($)$372,083 $390,992
Target Bonus (%)40% 40%
Actual Non-Equity Incentive Plan Compensation ($)$151,400 $169,258
Perquisites ($)$20,219 (commuting reimbursements)

Performance Compensation

Annual Cash Incentive Structure (2022)

MetricWeightingTargetActual AchievementPayout ($)Vesting
Corporate Goals (research, clinical development, business enabling)80% of bonus40% of base salary 110% achievement Included in $169,258 total NEIP payout Cash; paid after year-end
Individual Goals20% of bonus40% of base salary 100% achievement Included in $169,258 total NEIP payout Cash; paid after year-end

2022 program allowed corporate goals up to 140% of target; CEO bonuses based solely on corporate goals; other NEOs weighted 80% corporate/20% individual .

Equity Awards Granted (Grant Detail)

Grant DateAward TypeSharesGrant-Date Fair Value ($)Vesting
Feb 11, 2022Stock Options100,000 Included in $692,813 (2022 option awards total) 1/48 monthly from grant date
Feb 11, 2022RSUs12,500 Included in $123,406 (2022 stock awards total) 3 equal annual installments; fully vests at 3rd anniversary
Jul 11, 2022Stock Options75,000 Included in $692,813 (2022 option awards total) 1/36 monthly from grant date
Jul 11, 2022RSUs9,375 Included in $123,406 (2022 stock awards total) 3 equal annual installments; fully vests at 3rd anniversary

Outstanding Equity Awards (as of Dec 31, 2022)

AwardVesting CommencementExercisableUnexercisableExercise Price ($)ExpirationRSUs Unvested (#)RSUs Market Value ($)
OptionsJul 23, 2020146,754 96,151 17.00 Jul 23, 2030
OptionsFeb 25, 202152,708 62,292 30.07 Feb 25, 2031
OptionsFeb 11, 202220,833 79,167 6.94 Feb 11, 2032
RSUsFeb 11, 202212,500 $64,625 (at $5.17 close on 12/30/22)
OptionsJul 11, 202210,416 64,584 3.91 Jul 11, 2032
RSUsJul 11, 20229,375 $48,469 (at $5.17 close on 12/30/22)

Equity Ownership & Alignment

ItemDetail
Total Beneficial Ownership (as of April 10, 2023)305,383 shares; less than 1% of shares outstanding
Ownership ComponentsIncludes shares and options/warrants exercisable within 60 days per SEC rules
Hedging/PledgingProhibited by insider trading policy; no hedging or pledging of company securities (including margin accounts)
Section 16(a) ComplianceCompany disclosed late filings submitted Jan 23, 2024 for Overdorf and others related to RSU tax withholding sales; otherwise timely for FY2023

Employment Terms

  • Base/Bonus/Equity: Employment agreement at commencement (July 2020) provided base salary, target bonus, initial option grants, and severance framework .
  • Severance (no change-in-control window): If terminated without Cause or resigns for Good Reason, EVPs receive lump sum equal to 9 months’ base salary plus up to 9 months COBRA premium reimbursement; CEO receives 12 months .
  • Change-in-Control (three months before to twelve months after): If terminated without Cause or resigns for Good Reason, EVPs receive 12 months’ base salary plus target bonus, 12 months COBRA, and full acceleration of all unvested equity; CEO receives 18 months’ base plus 1.5x target bonus, 18 months COBRA, and full acceleration .
  • Definitions: “Cause” includes failure of duties after notice, dishonesty/fraud, law violations, confidentiality/invention assignment breaches, or crimes/acts of moral turpitude; “Good Reason” includes material reduction in salary/benefits, material diminution of duties (excluding mere title/reporting changes), or relocation >50 miles; cure and notice periods apply .

Say‑on‑Pay & Shareholder Feedback

  • 2025 Annual Meeting (June 5, 2025): Say‑on‑pay votes For 79,754,521; Against 3,796,829; Abstain 3,296,805; Broker Non‑Votes 11,334,985 .
  • 2024 Annual Meeting (June 5, 2024): Say‑on‑pay votes For 77,548,918; Against 1,895,328; Abstain 72,250; Broker Non‑Votes 4,642,317 .
  • Company noted “over 97%” approval in prior year’s say‑on‑pay (smaller reporting company disclosure context) .

Compensation Structure Analysis

  • Mix shift and risk: 2022 awards combined time‑vested RSUs (three annual installments) with sizable option grants vesting monthly over 48 and 36 months—tilting toward longer‑term, at‑risk equity rather than guaranteed cash .
  • Performance rigor: Corporate goals capped at 140% with 110% achievement in 2022; individual achievement at 100% for Overdorf, yielding a payout consistent with target math and aligning cash incentives to R&D and clinical milestones .
  • Perquisites: Commuting reimbursements of $20,219 in 2022; limited perquisites otherwise—shareholder‑friendly posture .
  • Governance protections: Strict anti‑hedging and anti‑pledging policy reduces misalignment and forced‑sale risks .

Investment Implications

  • Alignment and retention: Multi‑year monthly vesting across multiple option tranches (2020–2022) and RSUs through 2025 helps retain Overdorf and aligns incentives with long‑term value creation milestones; full acceleration on double‑trigger change‑in‑control is standard for EVPs but can modestly lower retention post‑transaction .
  • Selling pressure: RSU‑related tax withholding sales and timely Section 16 compliance (aside from one late filing batch) suggest mechanical selling rather than discretionary liquidation; anti‑pledging helps mitigate collateral‑driven sales risk .
  • Pay‑for‑performance: Cash incentive structure tied to clinical and business enabling goals with achievement modestly above target (110%) supports a performance‑linked payout; option-heavy equity exposure keeps Overdorf leveraged to stock performance and clinical outcomes .
  • Shareholder support: Strong say‑on‑pay outcomes in 2024 and 2025 indicate broad investor acceptance of the compensation framework, lowering governance overhang risk .