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Raymond Sanchez

Director at Alto Neuroscience
Board

About Raymond Sanchez

Raymond (Ramiro) Sanchez, M.D., age 64, was appointed as an independent director of Alto Neuroscience (ANRO) on August 12, 2025, serving as a Class II director with a term expiring at the 2026 Annual Meeting; the Board determined he meets NYSE independence standards . He brings 20+ years of life sciences leadership, currently serving as Senior Advisor at Bain Capital Life Sciences (since September 2024) and director at Rapport Therapeutics (since November 2024), following prior CMO roles at Cerevel Therapeutics and Avanir and senior clinical leadership at Otsuka . Dr. Sanchez trained in psychiatry at Yale School of Medicine (Chief Resident, fellow, instructor) and holds a B.A. in Psychology and M.D. from Northwestern University .

Past Roles

OrganizationRoleTenureCommittees/Impact
Cerevel Therapeutics Holdings, Inc.Chief Medical OfficerJan 2019 – Aug 2024Oversaw medical strategy; tenure concluded upon AbbVie acquisition
Otsuka Pharmaceutical Development & Commercialization, Inc.Sr. VP, Global Clinical Development (and prior roles)Nov 2013 – Jan 2019Led global clinical development
Avanir Pharmaceuticals, Inc.Chief Medical Officer (concurrent)Jun 2018 – Jan 2019Role concurrent with Otsuka tenure
International Society for CNS Drug DevelopmentExecutive Co-ChairNov 2017 – Jan 2022Industry governance role
Yale School of MedicineChief Resident, Fellow, Instructor (Psychiatry)Pre-industryAcademic clinical training and teaching

External Roles

OrganizationRoleTenureNotes
Bain Capital Life SciencesSenior AdvisorSep 2024 – PresentGlobal investment firm; advisory role
Rapport Therapeutics, Inc. (Nasdaq: RAPP)DirectorNov 2024 – PresentPublic biotech board
Various privately held biotechnology companiesDirectorNot disclosedAdditional private boards (names not disclosed)

Board Governance

  • Appointment and Class: Appointed August 12, 2025; Class II; term expires 2026 Annual Meeting .
  • Independence: Determined independent under NYSE and SEC rules .
  • Committee Assignments (current as of Aug 12, 2025): Member, Nominating & Corporate Governance Committee (NCGC); Board reconstituted on same date to balance classes .
  • Board Leadership: CEO Amit Etkin is Chair; Christopher Nixon Cox is Lead Independent Director with responsibilities for executive sessions and agendas .
DirectorAudit CommitteeCompensation & Management DevelopmentNominating & Corporate Governance
Husseini ManjiChair
Christopher Nixon CoxMemberChairMember
Gwill YorkChairMember
Andrew DreyfusMemberMember
Raymond SanchezMember
  • Board Attendance: FY2024 Board met 11 times; all then-directors attended ≥75% of meetings (pre-dates Sanchez’s tenure) .

Fixed Compensation

ComponentAmountPayment TermsNotes
Annual Board Cash Retainer$40,000Paid quarterly in arrears; pro-rated for partial quartersEligible to elect options in lieu of cash
NCGC Member Retainer$5,000Paid quarterly in arrears; pro-ratedAdditional fees apply if appointed to other committees

Performance Compensation

Award TypeGrant Size / ValueGrant TimingVesting / Terms
Initial Non-Employee Director Stock Option30,574 sharesOn appointment (Aug 12, 2025)Vests in equal monthly installments over 3 years; 10-year term
Annual Non-Employee Director Stock Option15,287 sharesEach Annual Meeting (starting 2026)Vests on earlier of 1-year anniversary or next Annual Meeting; 10-year term
Amended Policy (Nov 11, 2025) – Initial GrantLesser of 48,200 shares or $400,000 Black-Scholes valueUpon first election/appointment after Effective DateVests monthly over 3 years; accelerates on change in control
Amended Policy (Nov 11, 2025) – Annual GrantLesser of 24,100 shares or $200,000 Black-Scholes valueEach Annual Meeting after Effective DateVests by next Annual Meeting or 1-year; accelerates on change in control
  • Indemnification: Company standard indemnification agreement entered at appointment .
  • Clawbacks and Hedging/Pledging: Company maintains Dodd-Frank compliant incentive clawback policy and prohibits hedging, short-selling, derivative transactions, margin accounts, and pledging of shares .

Other Directorships & Interlocks

CompanyIndustry Link to ANROPotential Interlock/Conflict
Rapport Therapeutics (RAPP)Neuro/biotech adjacentNo related-party transactions with ANRO disclosed under Item 404(a)
Bain Capital Life SciencesInvestor/advisoryNo related-party transactions with ANRO disclosed

The Company reported no related-party transactions involving Dr. Sanchez requiring Item 404(a) disclosure .

Expertise & Qualifications

  • Deep CNS drug development leadership across big pharma and biotech; prior executive co-chair of ISCDD .
  • Psychiatry-trained clinician with academic leadership at Yale; Northwestern BA (Psychology) and MD .
  • Governance experience on public and private biotech boards; Senior Advisor to a leading life sciences investment firm .

Equity Ownership

InstrumentQuantityStatusNotes
Initial Director Option30,574 sharesUnvested; time-based monthly vesting over 3 yearsGranted per policy at appointment; 10-year term
Annual Director Option (2026 expected)15,287 sharesNot yet granted (timed to Annual Meeting)Vests by next Annual Meeting or 1-year
Section 16 Filings SetupN/APower of Attorney executedPOA for Forms 3/4/5 signed July 10, 2025

Beneficial ownership totals (shares owned, options exercisable) were not disclosed in available filings at appointment; Form 3 holdings were not located in the searched documents .

Governance Assessment

  • Strengths: Independent status; immediate engagement via NCGC membership; complementary CNS clinical expertise to ANRO’s precision psychiatry strategy; no Item 404(a) related-party transactions disclosed .
  • Alignment: Director pay mix combines modest cash retainers with time-based stock options; ability to elect options in lieu of cash increases equity alignment; hedging and pledging prohibited, supporting investor alignment .
  • Oversight Signals: Committee structure places Sanchez within governance pipeline while Audit and Compensation remain chaired by seasoned directors; Manji chairs NCGC, with Cox as Lead Independent Director, suggesting robust independent oversight .
  • Watch Items: November 2025 amendment increased share caps for director option grants (with Black-Scholes value limits), which warrants monitoring for pay escalation optics though value-capped; ensure continued linkage to market norms and independence of compensation decisions .

RED FLAGS: None identified in available filings (no conflicts, related-party transactions, or attendance issues disclosed for Sanchez) .