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Nimish Shah

Independent Director at Apogee Therapeutics
Board

About Nimish Shah

Independent Class II director (age 47 as of April 29, 2025), Apogee co‑founder and Venrock Healthcare Capital Partners investor; on Apogee’s board since June 2023 (previously on Apogee Therapeutics, LLC board of managers 2022–July 2023). Education: B.S. Pharmacy (Rutgers), M.P.H. (Columbia Mailman), M.B.A. (Columbia Business School); member, Columbia Business School Healthcare & Pharmaceutical Management Advisory Board .

Past Roles

OrganizationRoleTenureCommittees/Impact
Venrock Healthcare Capital PartnersPartner (focus on public and crossover biotech funds)2013–presentLeads investments; extensive biotech investing experience .
Instil Bio, Inc. (Nasdaq: TIL)DirectorUntil Dec 2021Board service during clinical-stage development .
LianBio (Nasdaq: LIAN)Board ObserverNot disclosedStrategic insights to management and board .
Biohaven Ltd. (NYSE: BHVN)Board ObserverNot disclosedInvestor perspective in neurology portfolio .
Viridian Therapeutics, Inc. (Nasdaq: VRDN)Board ObserverNot disclosedObserver to board; no voting role .
Dianthus Therapeutics, Inc. (Nasdaq: DNTH)Board ObserverNot disclosedObserver; immunology focus .
Apogee Therapeutics, LLCBoard of Managers2022–July 2023Co‑founder; pre‑IPO governance .

External Roles

OrganizationRoleTenureNotes
Columbia Business School Healthcare & Pharmaceutical Management Advisory BoardAdvisory Board MemberNot disclosedAcademic/industry advisory capacity .

Board Governance

  • Committee assignments: Member, Nominating and Corporate Governance Committee; not a chair .
  • Independence: Board determined Shah is independent under Nasdaq rules; CEO Henderson is the only non‑independent director .
  • Attendance: Board met five times in 2024; each director attended at least 75% of board and applicable committee meetings; all directors attended the 2024 annual meeting .
  • Board structure/context: Apogee has a classified board, supermajority provisions for certain actions, and plurality voting; independent Chair (Mark McKenna) with regular executive sessions of independent directors .

Fixed Compensation

ComponentAmount (2024)Notes
Fees Earned or Paid in Cash$44,000 Driven by $40,000 annual board retainer plus $4,000 Nominating Committee membership retainer per Feb 2024 director compensation policy .
  • Policy update effective at the 2025 annual meeting: Nominating Committee member retainer increases to $5,000; chair retainers increased (Audit $20,000; Compensation $15,000; Nominating $10,000) while board retainers unchanged ($40,000 director; $70,000 Chair) .

Performance Compensation

AwardGrant DetailFair ValueVestingNotes
Annual Stock Options (2024)10,370 options $349,828 Annual equity grants vest on the one‑year anniversary; director equity is solely options under the 2023 Plan .No RSUs/PSUs; options subject to plan limits .
  • No performance metrics disclosed for director compensation (e.g., TSR, EBITDA targets) – director equity consists of time‑vested stock options per policy .

Other Directorships & Interlocks

CompanyRoleInterlock/Notes
Instil Bio (Nasdaq: TIL)Former DirectorPrior directorship in cell therapy; ended Dec 2021 .
LianBio (Nasdaq: LIAN); Biohaven (NYSE: BHVN); Viridian (Nasdaq: VRDN); Dianthus (Nasdaq: DNTH)Board ObserverRepresents Venrock investor perspective; observer is non‑voting .
Venrock Healthcare Capital Partners III, L.P. and affiliatesVoting member of Venrock management entitiesVenrock affiliates collectively hold significant Apogee positions and have registration rights; Shah is a voting member, which can create perceived conflicts if investor interests diverge from minority holders .

Expertise & Qualifications

  • Biotech investing and crossover capital markets expertise; over a decade investing in public and private healthcare (since 2010), with focus at Venrock since 2013 .
  • Academic training in pharmacy and public health; MBA providing finance/strategy credentials .
  • Board and observer experience across multiple immunology/biopharma companies .

Equity Ownership

Holding TypeSharesOwnership/Power
Voting Common Stock (beneficially owned)1,776,289 Voting power 4.0% .
Non‑Voting Common Stock (beneficially owned)6,743,321 Convertible subject to 9.99% ownership cap for affiliates; increases possible with 61 days’ notice up to 19.99% limit .
Total Percentage Ownership14.3% Includes voting and non‑voting shares .
Stock Options held (as of Dec 31, 2024)15,919 Director option balance disclosed .
  • Anti‑hedging policy: Directors prohibited from short sales, derivatives, and hedging/monetization transactions in Company stock, supporting alignment and reducing risk of misaligned incentives .

Governance Assessment

  • Strengths: Independent status; active role on Nominating Committee; attendance at or above thresholds; independent Chair and robust committee structure; anti‑hedging and clawback policies in place .
  • Alignment signals: Majority of Shah’s 2024 director pay is equity‑based via stock options ($349,828 options vs. $44,000 cash), which emphasizes long‑term value creation over cash compensation .
  • Potential conflicts/RED FLAGS:
    • Significant beneficial ownership through Venrock‑affiliated entities with registration rights and ability to convert non‑voting shares (subject to caps), which may create perceived influence over governance and capital markets decisions; Shah is a voting member of Venrock management entities tied to these holdings .
    • Broader governance features (classified board; supermajority requirements; plurality voting) can entrench incumbent directors and limit shareholder action between annual meetings, potentially dampening investor confidence in rapid governance changes if needed .
  • Mitigants: Board’s formal related‑party transaction policy (post‑IPO) and Audit Committee oversight; independence confirmation considered investor relationships; executive and director compensation reviewed with an independent consultant (Alpine) with no identified conflicts .