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John Hamill

Senior Vice President, Chief Financial Officer and Secretary at Aprea Therapeutics
Executive

About John Hamill

John P. Hamill, 61, serves as Senior Vice President, Chief Financial Officer and Secretary of Aprea Therapeutics, Inc. (APRE). He joined Aprea on January 30, 2023, and is a CPA with a B.S. in Accounting/Business and Computer Science from DeSales University . In 2024, APRE paid no executive cash bonuses to maximize cash runway despite pre-established goals, and company pay-versus-performance shows TSR falling from $71.00 (value of $100) in 2023 to $49.70 in 2024, with net losses of $(14.3)mm and $(13.0)mm, respectively . Anti-hedging and pledging are prohibited, aligning insider behavior with shareholders .

Past Roles

OrganizationRoleYearsStrategic Impact
Windtree Therapeutics, Inc.SVP & CFOJun 2020–Jan 2023CFO for acute-care therapeutics developer
Consulting practiceFinancial/CFO servicesSep 2019–Jun 2020Provided CFO services incl. capital raising and budgeting
Trevena, Inc.VP Finance & CFOAug 2018–Aug 2019CFO for CNS-focused biopharma
Consulting practiceCFO servicesJun 2017–Jul 2018Interim CFO support (capital raising, budgeting)
NephroGenex, Inc.CFO; then CEO & CFOCFO Jan 2014–Mar 2016; CEO & CFO Apr 2016–May 2017Executive leadership through financing and corporate transitions

External Roles

No public company directorships or external board roles were disclosed for Mr. Hamill in the 2025 proxy .

Fixed Compensation

Metric20232024
Base Salary ($)387,917 437,100
Target Bonus (% of Salary)40% 40%
Actual Cash Bonus Paid ($)189,340 (non-equity incentive) 0 (Board determined no 2024 bonuses to maximize cash runway)
All Other Compensation ($)7,180

Performance Compensation

  • Annual cash bonus framework (2024): Corporate goals included regulatory/clinical milestones, preclinical activities, research goals, and corporate/IR objectives; target bonus 40% of base salary; actual payout: $0 .
Incentive TypeMetricWeightingTargetActualPayoutVesting/Timing
Annual Cash Bonus (2024)Corporate & individual goals (regulatory/clinical, preclinical, research, IR) Not disclosed40% of base salary Company elected not to pay for 2024 $0 Paid annually if awarded

Equity awards and vesting mechanics

  • Options: 10-year term; 25% vests at first anniversary, remaining 75% vests monthly over 36 months (service-based) .
  • RSUs: Vest one-third on each of the first, second, and third anniversaries of grant (service-based) .
  • Change-in-control acceleration: Mr. Hamill’s unvested equity fully accelerates if terminated without cause/for good reason within 12 months of a change in control (see Employment Terms) .

Equity awards outstanding as of 12/31/2024:

Grant DateAward TypeExercisableUnexercisableStrike ($)ExpirationRSUs Unvested (#)RSU MV ($)
1/30/2023Option12,931 14,056 9.92 1/29/2033 8,996 29,596.84 (at $3.29)
3/28/2024Option13,460 6.69 3/27/2034 3,365 11,070.85 (at $3.29)

Notes:

  • Options vest 25% at first anniversary then monthly; RSUs vest in three equal annual tranches .
  • Options accelerate on qualifying terminations within 12 months post-COC; RSUs fully accelerate on CoC or death/disability, with limited pro-rata vesting if terminated without cause before first anniversary for the first tranche .

Equity Ownership & Alignment

ItemDetails
Total Beneficial Ownership33,304 shares (includes 12,626 common shares; 19,667 options exercisable within 60 days; Tranche A/B warrants 505 each)
Ownership as % of SO<1% of 5,525,172 shares outstanding as of 4/10/2025
Vested vs. Unvested (12/31/24)Options exercisable: 12,931; unexercisable: 27,516; RSUs unvested: 12,361
Pledging/HedgingProhibited by policy (no pledging, no hedging, no short sales)
Ownership GuidelinesNot disclosed in proxy

Observation: As of 12/31/2024, APRE’s share price used for RSU valuation was $3.29, leaving Mr. Hamill’s 2023 and 2024 option tranches (strikes $9.92 and $6.69) out-of-the-money, limiting near-term exercise-driven selling pressure .

Employment Terms

TermSummary
Agreement EffectiveJan 30, 2023; amended Mar 25, 2025
Base Salary$436,800 effective Jan 1, 2024
Target Bonus40% of base salary
Severance (No COC)If terminated without cause/for good reason: 12 months base salary; prorated target bonus for year of termination; up to 12 months COBRA premium payments (subject to release)
Severance (COC within 12 months)18 months base salary; up to 18 months COBRA premium payments; immediate vesting of all unvested equity (subject to release)
Equity AccelerationFull acceleration of unvested equity on qualifying COC termination; option and RSU award terms include additional COC/death/disability/pro-rata provisions as noted above
Non-Compete/Non-Solicit12 months post-termination
280G Treatment“Better-of” (cutback to avoid excise tax if greater after-tax outcome)

Investment Implications

  • Pay-for-performance and cash conservation: Zero 2024 cash bonus despite established goals indicates discipline to preserve runway; combined with TSR decline to $49.70 (from $71.00) and narrowed net loss, compensation outcomes are conservative and cash-light for 2024 .
  • Retention risk vs. cost: Severance of 12 months (or 18 months post-COC) plus COBRA and full equity acceleration post-COC provide meaningful retention and transition protection, but also create potential change-of-control costs; equity acceleration could meaningfully increase realized pay in a transaction scenario .
  • Insider selling pressure: With options out-of-the-money at year-end 2024 (strikes $9.92 and $6.69 vs. $3.29 close), forced selling pressure from option exercises is limited near term; RSU vesting on 1/30 and 3/28 anniversaries can create periodic liquidity events, but policy prohibits hedging/pledging .
  • Alignment: Beneficial ownership is <1%, but anti-hedging/pledging, service-based vesting, and COC protections align incentives to company outcomes; no related-party transactions were disclosed for executives in 2024 .