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Diego Miralles

Director at Artiva Biotherapeutics
Board

About Diego Miralles, M.D.

Independent, non-employee director since May 2024; age 62. Currently CEO of AZURNA Therapeutics (since Jan 2024); previously CEO of Laronde (Dec 2020–Sep 2022) and Vividion (Aug 2017–Sep 2020). Medical degree from the University of Buenos Aires. Chairs Artiva’s Clinical Strategy Committee.

Past Roles

OrganizationRoleTenureCommittees/Impact
AZURNA Therapeutics, Inc.Chief Executive OfficerJan 2024–presentPrivate company CEO role in drug development
Laronde Inc.Chief Executive OfficerDec 2020–Sep 2022Early-stage biotech leadership
VividionChief Executive OfficerAug 2017–Sep 2020Built platform and programs; prior association with CEO of ARTV
Rady Children’s Institute for Genomic MedicineBoard member2008–presentPediatric genomics oversight
St. Vincent de Paul Village (Father Joe’s Villages)Board memberNot disclosedCommunity/charitable governance

External Roles

OrganizationRoleTenureCommittees/Impact
Contineum Therapeutics, Inc. (public)DirectorMar 2025–presentBiopharma board experience
NeuBase Therapeutics, Inc. (public)DirectorApr 2019–Apr 2021Public biopharma board experience
Rady Children’s Institute for Genomic MedicineDirector2008–presentLong-standing non-profit governance
Father Joe’s VillagesDirectorNot disclosedNon-profit governance

Board Governance

  • Committees: Chairs Clinical Strategy Committee; members include Daniel Baker, Laura Bessen, Brian Daniels, Laura Stoppel.
  • Board leadership: Independent, non-executive Chair (Brian Daniels); separation of Chair and CEO roles.
  • Attendance: Board met 4 times in 2024; no director attended fewer than 75% of combined board/committee meetings—Miralles met minimum attendance threshold.
  • Executive sessions: Regular sessions of independent directors held, typically each regular board meeting.
  • Independence: Proxy expressly lists Baker, Daniels, Hougen, Moore, Stoppel as “independent”; Miralles’ Nasdaq/SEC independence designation is not explicitly stated in that list (he is compensated as a non-employee director).

Fixed Compensation (Director)

Component2024 AmountNotes
Fees Earned or Paid in Cash ($)$10,824 Director cash fees in 2024
Option Awards ($, grant-date fair value)$108,144 ASC 718 value for director option awards in 2024
All Other Compensation ($)$160,000 Consulting fees under Miralles Consulting Agreement
Total ($)$278,968 Sum of 2024 director compensation components

Non-Employee Director Compensation Policy (effective July 2024):

  • Annual cash retainer: $40,000; Lead Independent Chair retainer: $30,000.
  • Committee retainers (non-chair): Audit $7,500; Compensation $6,000; Nominating & Corporate Governance $5,000.
  • Committee chair retainers: Audit $15,000; Compensation $12,000; Nominating & Corporate Governance $10,000.
  • Clinical Strategy Committee: annual cash retainer $6,000 ($15,000 for Chair).
  • Technical Operations Committee: annual cash retainer $15,000.
  • Equity: Initial option 27,500 shares; Annual option 13,750 shares; subject to plan limits.

Performance Compensation (Director)

Award TypeGrant DateShares/UnitsStrike PriceVesting2024 FV ($)
Stock option (consulting)Jan 202412,995 $5.18 Equal monthly over 6 months Included in $108,144
Stock option (consulting)Mar 202412,995 $5.18 Equal monthly over 6 months beginning May 2024 Included in $108,144
Annual/initial director optionsPolicy indicates 27,500 initial and 13,750 annual; specific 2024 director grant details for Miralles not separately disclosed beyond totals above

Performance metrics tied to director compensation:

  • None disclosed for director equity awards (director equity is time-based under policy; performance awards and metrics are described at the plan level, not used for director compensation).

Other Directorships & Interlocks

CounterpartyNaturePotential Interlock/Conflict Considerations
AZURNA Therapeutics (CEO)Private companyNo disclosed transactions with ARTV; outside CEO role.
Contineum Therapeutics (public)BoardNo disclosed ARTV transactions; biopharma landscape overlap is possible but not disclosed.
NeuBase Therapeutics (public)Former BoardNo disclosed ARTV transactions.
Rady Children’s Institute/Father Joe’s VillagesBoardsNon-profit roles; no ARTV transactions disclosed.

Context on related-party environment at ARTV:

  • Manufacturing and license agreements with GC Cell; GC Corp director (Yong‑Jun Huh) on ARTV Board.
  • RA Capital affiliates provide services (Blackbird, Carnot); ARTV director Laura Stoppel affiliated with RA Capital.
  • No specific transactions disclosed involving Miralles or AZURNA/Contineum/NeuBase beyond his consulting agreement with ARTV noted below.

Expertise & Qualifications

  • Executive leadership across biotech therapeutics; prior CEOs at Vividion and Laronde; current CEO at AZURNA.
  • Clinical strategy oversight; chairs Clinical Strategy Committee at ARTV.
  • Medical training (M.D.) and long-standing non-profit board service in genomics.

Equity Ownership

HolderForm of OwnershipQuantityAs-of Date% of Shares Outstanding
Diego Miralles, M.D.Options exercisable within 60 days25,990 Mar 31, 2025 <1% (based on 24,363,119 shares)
Diego Miralles, M.D.Outstanding stock options (total)25,900 Dec 31, 2024

Additional alignment/controls:

  • Hedging/pledging policy: Hedging and pledging prohibited without prior Board approval and pre-clearance; no pledging disclosed.
  • Director compensation limit: Aggregate director comp capped at $750,000 per year ($1,000,000 in year of first appointment).

Governance Assessment

  • Effectiveness: Chairs Clinical Strategy Committee, indicating domain leadership; board structure features independent chair and regular executive sessions supporting independent oversight. Attendance met minimum thresholds in 2024.
  • Independence/Conflicts: Miralles provided paid consulting to ARTV before and overlapping with his board appointment—$16,000 per month through IPO termination and two option grants; this is a potential perceived conflict but explicitly terminated at IPO and disclosed in director pay footnotes.
  • Compensation/Alignment: 2024 director pay includes cash fees plus option awards; beneficial ownership is small (<1%), primarily via options; hedging/pledging restrictions mitigate misalignment risks.
  • Related-party environment: Significant agreements with GC Cell (with ARTV director affiliations) and services from RA Capital affiliates (with another ARTV director affiliation); governance policies require Audit Committee oversight of related-person transactions. No specific related-party transactions attributed to Miralles beyond consulting agreement.

RED FLAGS: Prior consulting relationship and equity grants to Miralles while moving onto the board (terminated at IPO) require monitoring for ongoing influence; ensure continued independence and avoidance of future paid engagements.

Signals for investors: Clinical strategy leadership and multi-company CEO background could enhance R&D oversight; small personal ownership suggests alignment mainly through annual director options rather than material shareholding; board’s clear hedging/pledging prohibitions and independent chair structure support governance quality.