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Michael Panzara

Director at Athira Pharma
Board

About Michael Panzara

Michael Panzara, M.D., M.P.H., age 58, has served as an independent director of Athira Pharma since March 2022, and is a Class I director with a term through 2027 . He is Chief Medical Officer at Neurvati Neurosciences (a Blackstone Life Sciences portfolio company) since October 2022; previously he held senior development roles at Wave Life Sciences, Sanofi Genzyme, and Biogen, and taught neurology at Harvard Medical School with clinical appointments at Brigham & Women’s Hospital and Massachusetts General Hospital . Education: B.A. Biology, University of Pennsylvania (1989); M.D., Stanford University School of Medicine (1994); M.P.H., Harvard School of Public Health (2002) .

Past Roles

OrganizationRoleTenureCommittees/Impact
Neurvati Neurosciences, Inc.Chief Medical OfficerOct 2022–present
Wave Life Sciences Ltd.CMO; Head Therapeutics Discovery & DevelopmentCMO Nov 2018–May 2020; CMO & Head May 2020–Oct 2022
Wave Life Sciences Ltd.Franchise Lead, NeurologyJul 2016–Nov 2018
Sanofi GenzymeHead, Multiple Sclerosis/Neurology/Ophthalmology Therapeutic Area (Global Dev.)Not disclosed
BiogenVice President & Chief Medical Officer, NeurologyNot disclosed
Harvard Medical School; BWH & MGHInstructor in Neurology; Clinical appointmentsNot disclosed

External Roles

OrganizationRolePublic Company Board?Notes
Neurvati Neurosciences, Inc.Chief Medical OfficerNoBlackstone Life Sciences portfolio company
Wave Life Sciences Ltd.Senior executive rolesNo director role disclosedPublic company employment, not board service
Other public company directorshipsNone disclosedBiography lists no other public boards

Board Governance

  • Committee assignments: Member, Nominating & Corporate Governance; Chairman, Compliance Committee (established September 2024; first convened February 2025) .
  • Independence: Board determined he is independent under Nasdaq rules; also independent for committee service standards .
  • Attendance and engagement: Board held 7 meetings in FY2024; each director attended at least 75% of board and assigned committee meetings; Nominating & Governance held 2 meetings; Compensation held 4; Audit held 5; Compliance first convened in Feb 2025 .
  • Board leadership: Chairwoman of the Board is Kelly A. Romano; executive sessions of non‑employee directors chaired by the board chair or committee chair as appropriate .

Fixed Compensation

YearFees Earned or Paid in Cash ($)Committee Cash Structure (policy)Notes
202446,989 Policy retainer schedule: Director $40,000; Chair, Board $30,000; Audit Chair $15,000 / Member $7,500; Compensation Chair $10,000 / Member $5,000; Nominating Chair $8,000 / Member $4,000; Compliance Chair $10,000 / Member $5,000 (paid quarterly, prorated) Panzara served as Nominating member and Compliance Chair; cash paid reflects prorating and policy mechanics

Performance Compensation

Equity ComponentTermsVestingValue/Limit
Initial Option Award41,800 options on becoming non‑employee director; 10‑yr max term; exercise price = FMV at grant 1/36 monthly over 3 years, subject to service Annual director comp cap $500k; $750k in initial year (value per GAAP)
Annual Option Award20,900 options after each annual meeting; 10‑yr max term; exercise price = FMV at grant Vests on earlier of 1‑year from grant or day before next annual meeting; prorated if <12 months service since prior meeting Director comp cap as above
Change‑in‑ControlOutstanding director equity vests fully at CoC if serving as director through CoC date Immediate vesting upon CoC
2024 grant‑date fair value (options)$43,404 (aggregate grant‑date fair value for 2024) Director table shows option value per ASC 718

Other Directorships & Interlocks

Person/EntityRelationshipPotential Interlock/Conflict
Joseph Edelman / Perceptive Life SciencesEdelman is a director and managing member of Perceptive Advisors; Perceptive owns 14.1% of ATHA Major holder influence; board affirmed all non‑CEO directors (including Panzara) are independent, considering beneficial ownership
Michael PanzaraOther public company boardsNone disclosed in proxy biography

Expertise & Qualifications

  • Clinical development leadership across neurology (Sanofi Genzyme, Biogen, Wave Life Sciences); current CMO at Neurvati Neurosciences .
  • Academic training and appointments in neurology; MD (Stanford), MPH (Harvard), BA Biology (Penn); instructor at Harvard with clinical roles at BWH and MGH .
  • Governance experience via Nominating & Governance Committee membership and chairing Compliance Committee overseeing scientific and healthcare compliance risk .

Equity Ownership

HolderBeneficially Owned (Number of Shares)% OutstandingComposition/Notes
Michael Panzara71,853 <1% Consists of options exercisable within 60 days of April 4, 2025
  • Hedging/pledging: Directors are prohibited from hedging and pledging company securities under ATHA’s Insider Trading Policy .

Governance Assessment

  • Strengths:

    • Independent director with deep neurology R&D credentials; chairs newly formed Compliance Committee focused on scientific integrity and healthcare regulatory compliance—enhances board oversight of core operational risks .
    • Attendance threshold met (≥75% of board/committee meetings), indicating engagement; board held 7 meetings; relevant committees active (Audit 5, Compensation 4, Nominating & Governance 2) .
    • Director equity awards are standardized options with FMV strike and 10‑year term; clear vesting; CoC acceleration disclosed; annual compensation caps in place—reduces pay creep risk and aligns incentives .
  • Watch items / potential red flags:

    • Low personal beneficial ownership (<1%, composed of options only) may signal limited “skin-in-the-game” versus directors with material share ownership; monitor future equity uptake and exercise behavior .
    • Major shareholder presence (Perceptive at 14.1%; Edelman on board) can create influence dynamics; board explicitly reviewed such relationships in independence determinations, but continued vigilance on related-person transaction oversight is warranted .
    • Compliance Committee is new (established Sept 2024; first convened Feb 2025); effectiveness will depend on cadence, reporting, and integration with Audit risk oversight—track charter execution and joint risk analyses .
  • Policy protections:

    • Insider Trading Policy bans hedging, pledging, short sales, margin accounts; mitigates misalignment risks .
    • Audit Committee reviews related-party transactions; formal policy requires pre‑approval and bars conflicted member participation .

Fixed Compensation (Detail of Policy Schedule)

Cash ElementAnnual Amount ($)Applies to Panzara (2024)
Non‑employee Director Retainer40,000 Yes
Nominating & Governance Committee – Member4,000 Yes
Compliance Committee – Chair10,000 Yes
Other Committee Member/Chair FeesSee schedule (Audit member $7,500; Audit chair $15,000; Comp member $5,000; Comp chair $10,000; Nominating chair $8,000; Compliance member $5,000) Not applicable (Panzara not listed on Audit/Comp; not N&G chair)
  • Fees paid quarterly, prorated for service changes .

Performance Compensation (Director Equity Grant Design)

Award TypeSharesVestingTerm/Exercise PriceCoC TreatmentAnnual Cap
Initial Option Award41,800 1/36 monthly 10‑yr max; FMV strike Full acceleration $750k initial year
Annual Option Award20,900 Vests at 1 year or before next annual meeting; prorated if partial year 10‑yr max; FMV strike Full acceleration $500k per fiscal year
2024 Grant‑date Fair Value (Options)$43,404 Within cap

Other Notes

  • Insider trades: No Form 4 transactions for Dr. Panzara are disclosed in the 2025 proxy; additional Form 4 analysis can be provided on request .

Related Party Transactions (Policy Overview)

  • Formal policy requires Audit Committee pre‑approval/ratification; exempts certain de minimis or broadly shared transactions; conflicted Audit Committee members are recused; approval criteria include benefits, materiality, alternatives, and market terms .
  • Existing investors’ rights agreements from IPO era noted (including entities affiliated with other directors), but registration rights expired after three years; no Panzara‑specific related‑party transactions disclosed .

Governance Conclusion

  • Overall, Panzara’s independence, specialized neuroscience development expertise, and leadership of the Compliance Committee support board effectiveness in Athira’s core risk areas. Cash compensation is modest; equity compensation is standardized options with governance safeguards (caps, FMV strike, clear vesting). Key watchpoint is his low direct ownership (<1%) and the board’s dynamic with a significant shareholder on the board; mitigants include strict insider trading prohibitions and formal related‑party oversight .