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Garry Neil

Garry Neil

President and Chief Executive Officer at Avalo Therapeutics
CEO
Executive
Board

About Garry Neil

Garry Neil, M.D., age 71, is President & Chief Executive Officer of Avalo Therapeutics and has served on the Board since June 2022; he previously served as Chairman of the Board from August 8, 2022 until March 25, 2025 when Avalo separated the Chair and CEO roles . Dr. Neil’s background spans senior R&D leadership at Johnson & Johnson (2002–2012), venture roles at Apple Tree Partners, and C-suite and board experience at multiple biopharma companies; he holds a B.S. and M.D. from the University of Saskatchewan with postdoctoral training at the University of Toronto and Scripps Clinic . Pay-versus-performance disclosure shows Avalo’s cumulative TSR on a hypothetical $100 investment fell to $0 by 2023–2024 and net losses were $41.7M (2022), $31.5M (2023), and $35.1M (2024), underscoring a challenging shareholder return backdrop during his CEO tenure .

Past Roles

OrganizationRoleYearsStrategic Impact
Johnson & JohnsonCorporate VP of Science & Technology; Group President, J&J PRD2002–2012Led development/approvals across multiple therapeutic areas; senior R&D leadership
Apple Tree PartnersPartner2012–2013Life sciences PE investing; strategic portfolio oversight
Aevi Genomic Medicine (acquired by Avalo)Chief Scientific Officer2013–2020Helped transition assets to Avalo upon merger; guided R&D strategy
Avalo TherapeuticsChief Medical Officer; Chief Scientific Officer2020–2022Established scientific direction pre-CEO appointment

External Roles

OrganizationRoleYearsNotes
Celldex Therapeutics (Nasdaq: CLDX)DirectorCurrentPublic biopharma board service
Arena Pharmaceuticals (Nasdaq: ARNA)Director; ChairPrior; until acquisition in Mar 2022Acquired by Pfizer; leadership and board oversight
Zura Bio (Nasdaq: ZURA)DirectorPriorPublic biopharma board service
GTx, Inc. (Nasdaq: GTXI)DirectorPriorPublic biopharma board service
Reagan Udall Foundation; Center for Discovery and InnovationDirectorCurrentNon-profit/academic governance

Fixed Compensation

MetricFY 2023FY 2024
Base Salary (paid) ($)475,000 532,500
Base Salary Rate at Year-End ($)475,000 590,000 (increase effective June 30, 2024)
Target Bonus % of Base70% 70%
Actual Bonus Paid ($)166,250 501,800 (includes retention bonus)
Retention Bonus ($)47,500 (paid Feb 2024)

Performance Compensation

ComponentFY 2023FY 2024
Option Awards – Grant Date Fair Value ($)434,112 4,255,801
Stock Awards (RSUs) – Grant Date Fair Value ($)1,922,648
Incentive MetricWeightingTargetActualPayoutVesting
Discretionary corporate and individual goalsNot disclosedNot disclosedNot disclosedAnnual bonus payouts per Summary Comp TableRSUs and options vest per schedules below

Performance metrics, weightings, and specific targets were not disclosed; annual bonuses are discretionary and based on Compensation Committee assessment of Company and individual performance .

Equity Ownership & Alignment

ItemDetails
Total Beneficial Ownership194,720 shares; 1.77% of shares outstanding as of April 22, 2025
Composition47,140 common shares + 147,580 options exercisable within 60 days
Unvested RSUs194,600 unvested, granted 8/13/2024; scheduled to vest 3/28/2025, 3/28/2026, 3/28/2027
Unexercisable Options (not yet vested)500,400 shares at $9.88 strike; grant 8/13/2024; expire 8/13/2034
Hedging/PledgingInsider Trading Policy strongly discourages short sales, options, hedging transactions, margin accounts; no pledging disclosed
Ownership GuidelinesNot disclosed

Vesting Schedules and Potential Selling Pressure

  • 8/13/2024 RSU grant (194,600 shares) vests in three equal installments on March 28, 2025, March 28, 2026, and March 28, 2027, creating predictable supply events if shares are sold upon vesting .
  • 8/13/2024 option grant (500,400 shares; $9.88 strike) vests one-fourth on March 28, 2025 and the remainder monthly over 36 months thereafter; expiration 8/13/2034 .
  • No recent Form 4 insider transactions were found in 2024–2025 via filing catalog search, limiting visibility into selling cadence; continued monitoring is warranted [ListDocuments result: 0 Form 4s for 2024–2025].

Employment Terms

TermKey Provisions
Appointment and current roleAppointed CEO Feb 14, 2022 (via 8-K); earlier roles include CMO/CSO at Avalo and CSO at Aevi
Base salary and bonusBase increased to $475,000 in Feb 2022; target bonus up to 70% of base; discretionary, payable in cash or immediately vested equity at executive’s election
2024 base salary updateBase salary rate increased to $590,000 effective June 30, 2024
Equity awards (inducement/annual)3/8/2022 option grant; subsequent annual and special grants including 8/13/2024 options and RSUs; standard 4-year schedules and 1-year cliff where applicable
Non-compete / Non-solicitOne-year non-compete and non-solicit post-termination; confidentiality restrictions apply
Severance (termination without cause or for good reason)Accrued benefits; prior year unpaid bonus; 18 months base salary; prorated current-year bonus; full vesting of options with 12 months post-termination exercise; up to 12 months COBRA premiums
Change in Control (CoC)If termination without cause occurs within six months of a CoC, payments (accrued benefits, unpaid prior bonus, salary continuation) are made promptly after closing/termination; option vesting follows termination provisions

Board Governance

  • Board service history and dual-role implications: Dr. Neil served as Chairman while CEO from August 2022 to March 2025; the Board separated roles in March 2025 and appointed Michael Heffernan as Chairman to enhance independent oversight and allow CEO focus on operations . Dr. Neil is not independent under Nasdaq standards due to his CEO role .
  • Committees: Current Audit, Compensation, and Nominating & Corporate Governance Committees are fully independent; Dr. Neil is not listed as a member of these committees .
  • Board operations: Independent directors meet in executive session at least two times per year; Board met 12 times in 2024; all directors met at least 75% attendance thresholds .

Director Compensation

  • Employee directors receive no additional compensation for Board service; only non-employee directors receive fees and equity awards per policy .

Compensation Structure Analysis

  • Cash vs equity mix: FY2024 total compensation surged to $7.21M with substantial equity components (options $4.26M, RSUs $1.92M) versus FY2023 total of $1.08M, indicating a shift to equity-heavy pay aligned with longer-term retention and performance leverage .
  • Guaranteed vs at-risk: Base salary rose mid-2024; annual bonuses remain discretionary; significant unvested equity introduces multi-year at-risk compensation contingent on continued service and share performance .
  • Consultant and peer benchmarking: Aon Radford engaged in 2024 and 2025 to assess competitiveness and design; committee determined independence and lack of conflicts; peer group specifics not disclosed .

Related Party Transactions and Red Flags

  • Royalty Agreement (Aevi, July 2019): Certain investors, including LeoGroup Private Investment Access, LLC on behalf of Garry Neil, receive low-single-digit royalties on OSI Products; Company retains buyout rights after three years post first public launch; approved by independent directors/audit committee of Aevi . This pre-existing arrangement merits monitoring for perceived conflicts and disclosure sufficiency.
  • Option repricing/modification: No evidence of option repricing or award modifications disclosed in 2024–2025 materials .
  • Hedging/pledging: Company policy strongly discourages hedging/margin transactions; no pledging disclosed .

Multi-Year Compensation and Ownership

MetricFY 2023FY 2024
Total Compensation ($)1,075,362 7,212,749
Salary ($)475,000 532,500
Non-Equity Incentive ($)166,250 501,800
Option Awards – Fair Value ($)434,112 4,255,801
Stock Awards – Fair Value ($)1,922,648
Beneficial Ownership (shares; %)194,720; 1.77%
Exercisable Options (within 60 days) (#)147,580
Unvested RSUs (#)194,600
Unexercisable Options (#)500,400

Performance & Track Record

  • Achievements: Led programs resulting in new medicine approvals across oncology, anemia, infections, CNS/psychiatric disorders, pain, genitourinary and GI diseases during prior pharma tenures; brings extensive R&D leadership .
  • Company performance: Pay-versus-performance shows TSR decoupled from CAP; cumulative TSR values fell to $0 by 2023–2024 and net losses persisted, highlighting ongoing execution and financing hurdles typical of development-stage biopharma .

Equity Award Details and Vesting

GrantTypeSharesStrike/ValueVestingExpiration
8/13/2024Stock Options500,400$9.8825% on 3/28/2025; remaining monthly over 36 months8/13/2034
8/13/2024RSUs194,6001/3 on 3/28/2025; 1/3 on 3/28/2026; 1/3 on 3/28/2027

Board Service History and Dual-Role Implications

  • Board tenure: Director since June 2022; Chairman Aug 2022–Mar 2025; now CEO/Director under independent Chair .
  • Implications: The 2025 move to separate Chair and CEO strengthens independent oversight and mitigates dual-role concerns common to small-cap biotech governance; Dr. Neil remains a non-independent director due to his executive role .

Investment Implications

  • Alignment and retention: Large 2024 equity grants with multi-year vesting, coupled with 18-month salary continuation and option acceleration on qualifying termination, suggest strong retention incentives but also predictable vesting-related supply events on 3/28 annually through 2027 .
  • Pay-for-performance optics: Discretionary bonuses without disclosed metrics and weak TSR/net losses may draw investor scrutiny; however, equity-heavy 2024 grants increase at-risk compensation tied to share outcomes over the next three years .
  • Governance posture: Separation of Chair/CEO in 2025, fully independent committees, and discouragement of hedging/margin transactions are positives; continued monitoring of legacy royalty-related party arrangement is advisable .
  • Trading signals: Upcoming RSU vesting dates and option cliff in March 2025, 2026, and 2027 represent potential selling pressure windows; absence of recent Form 4s in 2024–2025 limits visibility—investors should watch for 10b5-1 plan adoptions and sales disclosures around vesting events (ListDocuments: no 2024–2025 Form 4s).