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Barbara Ryan

Independent Director at Azitra
Board

About Barbara Ryan

Barbara Ryan, 65, has served as an independent director of Azitra since June 2023; she is a veteran capital markets advisor and former sell-side pharmaceutical research analyst with 30+ years on Wall Street, and founder of Barbara Ryan Advisors (2012) focused on financings, M&A, SEC reporting, valuation, and strategy across life sciences . Her background includes executive team service and disclosure committee membership at Radius Health (2014–2017), and leadership of pharmaceutical research at Deutsche Bank/Alex Brown for 19 years after beginning her research career at Bear Stearns in 1982 . She currently chairs Azitra’s Compensation and Nominating & Corporate Governance committees and serves on the Audit Committee, with the Board affirming her independence under NYSE American rules .

Past Roles

OrganizationRoleTenureCommittees/Impact
Barbara Ryan AdvisorsFounder; capital markets & communications2012–presentAdvised large life sciences financings/M&A; notable work on Shire (defense vs AbbVie), Shire–Baxalta, Allergan (defense vs Valeant), Perrigo (defense vs Mylan)
Radius HealthExecutive team member; Disclosure CommitteeJan 2014–Dec 2017Corporate disclosure oversight; capital markets engagement
Deutsche Bank/Alex BrownManaging Director; Head of Pharmaceutical Research19 yearsLed pharma coverage; institutional investor engagement
Bear StearnsResearch Analyst (Pharma)Began 1982Early sell-side coverage foundation

External Roles

OrganizationRoleNotes
MiNK Therapeutics (Nasdaq: INKT)Director; Audit Committee ChairCurrent public company board seat
INVO Bioscience (Nasdaq: INVO)DirectorCurrent public company board seat
Invidior PLC (LON: INDV)DirectorCurrent public company board seat
The Red Door Community (formerly Gilda’s Club NYC)DirectorNon-profit
Fabulous Pharma FemalesFounderAdvances women in biopharma
Pharmaceutical Executive MagazineEditorial Advisory BoardIndustry thought leadership
GLG InstituteFaculty MemberExpert network faculty
Prix GalienExecutive Advisory BoardIndustry recognition body

Board Governance

  • Independence: Board determined Barbara Ryan is independent per SEC and NYSE American rules; Azitra’s Board has 4 members with 2 independent (50%), meeting NYSE American requirements for smaller reporting companies .
  • Committees: Member, Audit Committee; Chair, Compensation Committee; Chair, Nominating & Corporate Governance Committee .
  • Attendance: All directors attended at least 75% of Board and applicable committee meetings in 2024; however, Ms. Ryan did not attend the 2024 annual meeting (virtual) along with Mr. Schroer; attendance at annual meetings is encouraged but not required .
  • Committee activity (2024): Audit met 4 times; Compensation met 3 times; Nominating & Corporate Governance met once .
  • Board leadership: No lead independent director; oversight via independent committees and full Board risk oversight assignments .
CommitteeBarbara Ryan Role2024 Meetings
AuditMember4
CompensationChair3
Nominating & Corporate GovernanceChair1

Fixed Compensation

ComponentAmountNotes
Fees earned or paid in cash (2024)$42,983Actual cash fees paid to Barbara Ryan for director service in 2024
Annual Board retainer (policy)$25,000Non-executive directors; paid quarterly, prorated as applicable
Committee chair retainer (Comp; Nom/Gov)$5,000 eachAnnual retainer for chairs
Audit Committee member retainer$3,500Annual retainer for non-chair members
Meeting feesNoneNot part of policy; reasonable expenses reimbursed

Performance Compensation

Option Award DetailGrant DateSharesExercise PriceVestingExpiration
Non-employee director optionSept 8, 2023333$62.1025% (83) on first anniversary; 75% (250) monthly over 36 months thereafter, conditioned on Board service10 years from grant
  • No director RSUs/PSUs or option grants in 2024; 2023 options are time-based only without performance metrics tied to TSR/revenue/EBITDA/ESG .
Performance MetricThreshold/TargetWeightingOutcome
None disclosed for non-employee directors

Other Directorships & Interlocks

CompanyRelationship to AZTRPotential Interlock/Conflict
MiNK Therapeutics (Nasdaq: INKT)Unrelated board seat; Audit ChairNo AZTR-related party transactions disclosed since Jan 1, 2023
INVO Bioscience (Nasdaq: INVO)Unrelated board seatNo AZTR-related party transactions disclosed since Jan 1, 2023
Invidior PLC (LON: INDV)Unrelated board seatNo AZTR-related party transactions disclosed since Jan 1, 2023
The Red Door CommunityUnrelated non-profitNo AZTR-related party transactions disclosed since Jan 1, 2023

Expertise & Qualifications

  • Capital markets/M&A: Extensive experience across equity/debt, valuation, M&A defense, corporate strategy for life sciences; founder of Barbara Ryan Advisors .
  • Governance/Disclosure: Executive team member and disclosure committee experience at Radius Health .
  • Audit oversight: Audit Committee member at AZTR; Audit Chair at MiNK; Board designated John Schroer (not Ryan) as the audit committee financial expert, while both members read/understand fundamental financial statements .
  • Industry leadership: Roles with Fabulous Pharma Females, Pharmaceutical Executive Magazine, GLG Institute, Prix Galien .

Equity Ownership

HolderShares Beneficially Owned% of OutstandingNotes
Barbara Ryan153<1%Includes 138 shares issuable upon exercise of currently exercisable options (within 60 days of May 28, 2025)
Options held (as of Dec 31, 2024)333Non-employee director options outstanding as of year-end 2024
  • Hedging/pledging prohibited: Company Insider Trading Policy prohibits short sales, publicly traded options, hedging transactions, margin accounts and pledged securities by directors .

Governance Assessment

  • Strengths: Independent status; multi-committee leadership (Compensation and Nominating & Corporate Governance); meets attendance thresholds; audit committee engagement; robust insider trading and hedging/pledging prohibitions .
  • Alignment concerns: Minimal share ownership (<1%) and modest option holdings may signal limited “skin in the game” relative to governance best practices for alignment .
  • Engagement flag: Did not attend the 2024 annual meeting (virtual), which may be viewed negatively by some investors despite meeting overall attendance requirements .
  • Structural considerations: No lead independent director; concentration of committee chair roles (Compensation and Nominating & Corporate Governance) in a small-board context may warrant ongoing monitoring of balance and oversight .
  • Conflicts/Related party exposure: No related-party transactions disclosed since January 1, 2023; presence of multiple external public boards raises typical interlock considerations but no AZTR-specific transactions or conflicts are disclosed .

RED FLAGS: Low personal ownership; absence from the 2024 annual meeting; dual chair roles (Compensation and Nominating) without a lead independent director .