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David Raben

Chief Medical Officer at Bicara Therapeutics
Executive

About David Raben

David Raben, M.D., is Chief Medical Officer at Bicara Therapeutics (BCAX), a board‑certified radiation oncologist who joined as a consultant in May 2023 and was appointed CMO in July 2023; he is 61 years old as of April 14, 2025 . Prior to Bicara, he led late‑stage product development at Amgen (Nov 2021–May 2023), including the recently FDA‑approved tarlatamab program in SCLC, and previously led late‑stage development for lung/skin/HNC at Genentech (Sep 2019–Jun 2021); he was Professor of Radiation Oncology at the University of Colorado Health (1998–2019) . His education includes a BA (Duke, 1985), M.D. (Wake Forest, 1990), and residency at Johns Hopkins (1994) .

Past Roles

OrganizationRoleYearsStrategic impact
Bicara TherapeuticsChief Medical OfficerJul 2023–PresentLeads clinical strategy and development; joined as consultant in May 2023
AmgenVP, Late-Stage Product DevelopmentNov 2021–May 2023Led the tarlatamab (SCLC) program through FDA approval
GenentechVP, Late-Stage Product Dev. (lung, skin, HNC)Sep 2019–Jun 2021Oversaw late-stage development in key oncology indications
University of Colorado HealthProfessor, Radiation OncologyMay 1998–Sep 2019Academic and clinical leadership in oncology

External Roles

OrganizationRoleYearsNotes
None disclosed in SEC filingsNo public company board roles identified for Raben in the company’s filings

Fixed Compensation

ItemDetail
Base salary (most recent disclosed)Not disclosed for Raben; BCAX (as an EGC) only disclosed 2024 compensation for CEO, COO, and CFO as named executive officers .
Target bonus %Not disclosed for Raben .
Actual annual bonusNot disclosed for Raben .
PerquisitesCompany states perquisites are not a significant component of executive compensation .

Performance Compensation

  • No executive‑specific performance metric weights/targets or payouts were disclosed for Raben (he was not a named executive officer in 2024) .

Equity Ownership & Alignment

Beneficial ownership snapshots

As-of dateCommon shares ownedNotes
Sep 12, 2024 (Form 3)35,497Initial statement of beneficial ownership at IPO
Apr 14, 2025 (Proxy reference)35,497Footnote in group total also identifies Raben’s holdings (plus options within 60 days)
  • Company had 54,536,218 shares outstanding as of April 14, 2025 (context for ownership levels) .

Outstanding option grants (Form 3 detail)

Grant descriptionUnderlying sharesExercise price ($)ExpirationVesting schedule
Option grant (vested 25% on 7/24/2024; remainder quarterly)150,8703.7908/08/203325% on 07/24/2024; remaining 75% in 12 equal quarterly installments, subject to service
Option grant (16 quarterly installments from 08/08/2023)70,3193.7908/08/2033Vests in 16 equal quarterly installments from 08/08/2023, subject to service
Option grant (16 quarterly installments from 12/14/2023)134,8925.4512/14/2033Vests in 16 equal quarterly installments from 12/14/2023, subject to service
Option grant (16 quarterly installments from 08/06/2024)216,3689.2408/06/2024Vests in 16 equal quarterly installments from 08/06/2024, subject to service
  • Aggregate Option Holdings (Form 3): 572,449 underlying shares across the four grants (sum of rows) .
  • As of Apr 14, 2025, 157,122 of Raben’s options were exercisable within 60 days (identified in proxy group footnote) .

Trading plans, hedging/pledging, and clawback

ItemTerms
10b5‑1 trading plan adoptionAdopted Feb 12, 2025; plan contemplates potential sales “up to 104,000 shares,” in effect until the earlier of June 24, 2026 or plan completion/termination .
Insider trading policyProhibits derivative transactions of company stock and purchases of derivative securities providing economic equivalent of ownership; addresses compliance and risks of margin/pledged securities (policy discussion) .
Clawback policyCompany maintains an SEC/Nasdaq‑compliant compensation recovery (clawback) policy covering current and former executive officers following a required financial restatement .

Employment Terms

TopicDetail
Employment statusAt‑will executive officer (general company practice); specific employment agreement terms were not disclosed for Raben in the proxy .
Non‑compete/Non‑solicitThe proxy describes standard restrictive covenants for NEOs; there was no Raben‑specific agreement disclosed .
Severance/Change‑in‑control termsNot disclosed for Raben; detailed severance and CIC economics were provided only for CEO/COO/CFO .

Investment Implications

  • Compensation transparency is limited for Raben (not a 2024 NEO), reducing visibility into his pay‑for‑performance alignment; company‑level policies include a clawback and restrictions on derivatives, which are shareholder‑friendly .
  • Option overhang and quarterly vesting cadence can create steady potential share supply; Raben’s Form 3 shows four sizable option grants vesting in equal quarterly installments beginning 2023–2024; he also adopted a 10b5‑1 plan to sell up to 104,000 shares through June 2026, indicating potential selling pressure managed via a structured plan .
  • Skin‑in‑the‑game is present but modest in common shares (35,497); options within 60 days of exercisability were 157,122 as of April 14, 2025, providing leverage to upside but also future supply as tranches vest .
  • Track record mitigates execution risk: leadership of an FDA‑approved SCLC program (tarlatamab) at Amgen and late‑stage oncology development at Genentech/Amgen support credibility in Bicara’s oncology pipeline execution .

Notes on data gaps: Raben‑specific base salary, target bonus, and incentive metric details were not disclosed (company limited NEO disclosures to CEO/COO/CFO for 2024) . Policy disclosures (clawback, trading/derivatives) apply at the company level and include executive officers .