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Nancy Hutson

Chair of the Board at BIOCRYST PHARMACEUTICALSBIOCRYST PHARMACEUTICALS
Board

About Nancy J. Hutson, Ph.D.

Independent director and Chair of the Board at BioCryst Pharmaceuticals (BCRX). Age 75; director since 2012; elected Chair in March 2023. Ph.D. in physiology (Vanderbilt) and B.A. (Illinois Wesleyan). 25-year Pfizer tenure culminating as SVP Global R&D and site director of Groton/New London Laboratories; extensive R&D leadership in biopharma.

Past Roles

OrganizationRoleTenureCommittees/Impact
Pfizer, Inc.SVP, Global R&D; Director, Groton/New London Labs~25 years; retired 2006Led large R&D operations; deep industry/R&D experience
BioCryst PharmaceuticalsDirector; Chair of the BoardDirector since 2012; Chair since Mar-2023Board leadership; liaison between management and Board

External Roles

OrganizationRoleStatus/TenureNotes
Clearside Biomedical, Inc.DirectorCurrentPublic biopharma board service
Hatteras Venture PartnersScientific Advisory Board MemberCurrentVenture advisory in life sciences
Endo International plcDirectorPriorPublic company board; pharma
Inspire Pharmaceuticals, Inc.DirectorPriorPublic company board
Cubist Pharmaceuticals, Inc.DirectorPriorPublic company board
PhaseBio Pharmaceuticals, Inc.DirectorPriorPublic company board

Board Governance

  • Independence: Board determined Dr. Hutson is independent under Nasdaq rules (9 of 10 directors independent).
  • Roles/Committees: Chair of the Board; Chair of Compensation Committee; Member, Corporate Governance & Nominating Committee.
  • Leadership structure: Independent Chair presides over Board and executive sessions; executive sessions held at every regularly scheduled Board meeting.
  • Attendance/Engagement: Board met 4 times in 2024; each member attended ≥75% of Board and committee meetings; Chair attended the 2024 annual meeting in person.
  • Term limits: Board waived non-management director term limits to allow Dr. Hutson an additional three-year term due to qualifications and contributions (she abstained from votes/discussions).
  • Stock ownership guidelines: Non-employee directors must hold ≥3x annual cash retainer; compliance for all covered individuals as of 12/31/2024.
  • Compensation committee governance: Members are independent and non-employee; no interlocks or Item 404 relationships in 2024; uses Aon as independent compensation consultant.

Fixed Compensation

ComponentAmount ($)Notes
Total cash fees (2024)107,500Disclosed in 2024 director compensation table
Annual Chair retainer80,000Director Compensation Policy (2024 schedule)

Committee retainer schedule (context): Audit Chair $20,000; Compensation Chair $15,000; Corporate Governance & Nominating Chair $10,000; member retainers lower as disclosed.

Performance Compensation

Equity AwardGrant DateQuantity (#)Fair Value ($)VestingNotes
Annual RSUs2024 annual meeting (Jun 12, 2024)6,82042,96612-monthRSUs valued at $6.30 closing price on grant date
Annual Stock Options2024 annual meeting (Jun 12, 2024)49,933227,50012-monthExercise price set at FMV on grant date per policy; options valued per ASC 718
  • Director equity mix under policy: prior to Apr 21, 2025 grants payable 70% options/30% RSUs; amended to 60% options/40% RSUs thereafter.
  • Plan features: minimum 1-year vesting (limited exceptions), no dividends on unvested awards, clawback applies, no gross-ups, no repricing without shareholder approval, double-trigger vesting upon change of control if assumed; full vesting if not assumed.

Other Directorships & Interlocks

CompanyTypeShared ties with BCRX ecosystemNotes
Clearside Biomedical, Inc.PublicNone disclosedCurrent board service
Prior boards (Endo, Inspire, Cubist, PhaseBio)PublicNone disclosedHistorical board service

Related-party transactions: None requiring disclosure since Jan 1, 2024; Audit Committee pre-approves related-party transactions.

Expertise & Qualifications

  • Deep pharmaceutical R&D leadership including SVP Global R&D at Pfizer and site direction of a major R&D facility; strong pre-clinical and development background.
  • Board experience across multiple public biopharma companies; current service on Clearside Biomedical and life sciences venture advisory.
  • Skills matrix recognition for pharmaceutical R&D and early/late stage clinical development expertise.

Equity Ownership

ItemAmountDetail
Total beneficial ownership330,665As of Apr 14, 2025; under 1% of class (*)
Options exercisable (≤60 days)244,027Included in beneficial ownership footnote (10)
RSUs vesting (≤60 days)6,820Included in beneficial ownership footnote (10)
Ownership % of shares outstanding<1%Asterisk denotes less than one percent

Governance Assessment

  • Strengths: Independent Chair with seasoned pharma R&D expertise; executive sessions every meeting; robust stock ownership guidelines with confirmed compliance; independent Compensation Committee using an external consultant; no related-party transactions disclosed; say-on-pay support >95% in 2024.
  • Alignment: Director equity grants (RSUs/options) and ability to elect stock in lieu of cash; plan includes clawback provisions and prohibits hedging.
  • RED FLAGS/Watch items: Board’s waiver of term limits for Dr. Hutson to extend tenure (potential entrenchment signal, though justified by expertise); elevated company-wide equity overhang noted in plan discussion (broader compensation context).
  • Overall: Governance practices (independence, committee structure, ownership guidelines, anti-hedging, clawback) support investor confidence; continued monitoring of director tenure policies and equity usage advisable.