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Michael Hitchcock, Ph.D.

Michael Hitchcock, Ph.D.

Interim Chief Executive Officer at Biomea Fusion
CEO
Executive
Board

About Michael Hitchcock, Ph.D.

Michael J.M. “Mick” Hitchcock, Ph.D. is Interim Chief Executive Officer (since March 25, 2025) and a Class III director of Biomea Fusion (director since March 2021; term through 2027). He is 75 years old, with a Ph.D. in microbiology (University of Melbourne), B.Sc./M.Sc. in biochemistry (UMIST), and post-doctoral research at Georgetown and NIH. Prior roles include 27 years at Gilead Sciences in senior R&D, portfolio, alliance, and strategy positions, and earlier infectious disease R&D at Bristol-Myers Squibb; he is also an Adjunct Professor of Microbiology at UNR Medical School and a founder/director of Renogenyx (FSHD) . As interim CEO, his pay comprises salary, target bonus, and a time-vested option; BMEA did not disclose TSR/revenue/EBITDA performance metrics tied to his 2025 award, and the company paid no 2024 NEO bonuses under its discretionary framework .

Past Roles

OrganizationRoleYearsStrategic Impact
Gilead SciencesVarious VP and senior advisor roles in project/portfolio mgmt., alliance mgmt., strategic planning, medical affairs, research1993–2019Involved in development/commercialization of antivirals (e.g., tenofovir, adefovir, cidofovir, elvitegravir, oseltamivir, stavudine, didanosine) for HIV, HBV, influenza, CMV and others
Bristol-Myers SquibbInfectious disease research and project planning roles1980–1993Early R&D leadership in anti-infectives
University of Nevada, Reno (UNR) Med SchoolAdjunct Professor of Microbiology2016–presentAcademic leadership, talent development

External Roles

OrganizationRoleYearsNotes
RenogenyxFounder and Board memberNot disclosedBiotech focused on FSHD
UNR FoundationPast ChairNot disclosedBoard leadership (as noted in company PR)

Board Governance

  • Service history and current status: Director since March 2021; currently Class III director (term ends at 2027 meeting) and Interim CEO (not independent under Nasdaq due to officer status) .
  • Committee roles: Previously served on Audit and Compensation Committees; resigned upon becoming Interim CEO (March 2025), causing a temporary Nasdaq audit committee composition deficiency the company is curing within the allowed period .
  • Board structure and safeguards: Lead Independent Director (Eric Aguiar, M.D.) in place; Board may appoint a new chair after prior chair’s departure in March 2025; all directors except Hitchcock and the President/COO deemed independent .
  • Attendance: Each director attended at least 75% of board/committee meetings in 2024 .

Fixed Compensation

Year/RoleBase Salary ($)Target Bonus (%)Actual Bonus PaidNotes
2025 Interim CEO (effective 3/25/25)633,000 50% (pro-rated) Not disclosedApproved March 26, 2025
2024 Director (non-employee)56,500 N/AN/ADirector fees prior to CEO appointment
  • As an EGC, BMEA is not required to hold say‑on‑pay votes, and did not seek such approval in 2025 .

Performance Compensation

InstrumentGrant/Approval DateSize/ValueExercise/StrikeVestingPerformance MetricsPayout/Status
Stock Option (CEO grant)3/26/2025 approval (effective from 3/25/2025) 350,000 options $2.52 12 equal monthly installments over 12 months from Effective Date, subject to service None disclosed (time-vested) Ongoing vesting through 12-month schedule
Director annual option (2024)2024 (policy-based)$184,996 grant date fair value Not disclosedAnnual director grant vests in full by next AGM or 1-year from grant per policy Director service only Vests per policy

Note: 2024 NEO annual bonuses were discretionary; the company paid no 2024 bonuses to NEOs (context for program design; Hitchcock was not an NEO in 2024) .

Equity Ownership & Alignment

ItemDetail
Total beneficial ownership133,100 shares/derivatives (15,000 common directly; 118,100 options exercisable within 60 days of 3/31/2025)
Ownership % of SO<1% (asterisked in table)
Director options held (12/31/2024)Options to purchase 110,792 shares (aggregate)
Hedging/PledgingInsider Trading Policy prohibits hedging and pledging by executive officers and non-employee directors
Lock-up considerationsIn Oct 2025 underwritten offering, the company used a standard form of lock-up agreement; Hitchcock signed the underwriting agreement as Interim CEO (company party). Standard lock-ups can temporally restrict insider sales around offerings (form attached; term not specified)

Employment Terms

TermDetail
AppointmentInterim Chief Executive Officer effective March 25, 2025
Compensation elementsBase salary $633,000; 50% target cash bonus (pro‑rated); 350,000 stock options at $2.52, vesting monthly over 12 months from 3/25/2025
Severance / CICNo specific severance/CIC terms for Dr. Hitchcock were disclosed in the cited filings. Company-level Severance Agreements (with 280G gross‑ups) are described for certain NEOs (Butler, Valle, Erdtmann); applicability to Hitchcock not disclosed .
ClawbackCompensation recovery policy adopted Nov 17, 2023 (effective Oct 2, 2023) for incentive comp tied to financial reporting measures in event of restatement

Director Compensation (context)

2024 Director CompensationCashOption Awards (Grant Date FV)Total
Michael J.M. Hitchcock, Ph.D.$56,500 $184,996 $241,496
  • Director pay policy: $35,000 base retainer; additional retainers for leadership and committee roles; initial and annual option grants with Black‑Scholes values of $360,000 and $185,000, respectively, with vesting per policy .

Performance & Track Record

  • Clinical execution: Hitchcock cited “positive Phase II data in insulin‑deficient patients” for icovamenib as a major milestone; focus on advancing late‑stage development and regulatory engagement .
  • Governance and continuity: Following the March 2025 leadership transition, BMEA promptly disclosed and is curing an audit committee composition deficiency created by Hitchcock’s move from independent director to Interim CEO .

Compensation Structure Analysis

  • Mix and risk profile: Interim CEO package emphasizes time‑vested options (12‑month monthly vest), aligning near‑term retention with equity upside; no performance‑conditioned equity disclosed for 2025 CEO grant .
  • Discretionary cash design: For 2024, the company used discretionary annual bonuses for NEOs and paid none, signaling cost discipline and limited cash payouts absent clear goal attainment; however, Hitchcock was not an NEO in 2024 .
  • Governance controls: EGC status (no say‑on‑pay), clawback policy in place, and prohibition on pledging/hedging support alignment and risk mitigation .
  • Advisor independence: Compensation Committee retained Aon Consulting as independent advisor; committee assessed independence and found no conflicts .

Investment Implications

  • Alignment and retention: The 12‑month, monthly-vesting option (350,000 at $2.52) creates a clear short-term retention tether and leverage to clinical/regulatory milestones. Limited disclosed ownership (<1%) suggests alignment primarily via options rather than large common stock holdings .
  • Selling pressure and liquidity: Prohibition on pledging/hedging reduces adverse alignment risks; the October 2025 underwritten offering included standard lock‑up documentation, which typically tempers near‑term insider selling, though specific lock‑up terms were not disclosed in the excerpts .
  • Governance risk watch‑items: Temporary audit committee non‑compliance tied to Hitchcock’s transition is being addressed within Nasdaq’s cure period, but it remains a monitoring item until fully cured .
  • Pay-for-performance transparency: Absence of explicit performance metrics for the 2025 interim CEO award (time‑based vesting) shifts emphasis to execution outcomes (trial progress, financing, and regulatory steps) rather than predetermined financial targets; 2024 NEO bonuses were not paid under the discretionary framework, indicating restraint amid development-stage realities .

Net: Incentive design favors near‑term retention and upside participation as BMEA advances icovamenib; governance structures (lead independent director, clawback, hedging/pledging bans) are positives, while interim status and committee composition cure are near‑term risks to monitor. Clinical and financing milestones remain the primary valuation levers under Hitchcock’s interim leadership .

Citations

  • Proxy (DEF 14A, 4/28/2025):
  • 8‑K (3/27/2025 Leadership Transition): CEO appointment and compensation terms ; audit committee cure disclosure ; PR background .
  • 8‑K (10/6–10/7/2025 Offering): Underwriting agreement/lock‑up form and signatures by Hitchcock as Interim CEO .