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Shawn Tomasello

Director at Cabaletta Bio
Board

About Shawn Tomasello

Independent director at Cabaletta Bio (CABA) since July 2023; Age 66 as of April 28, 2025; B.S. in Marketing (University of Cincinnati) and MBA (Murray State University). Former commercial leader across cell/gene therapy and hematology-oncology, including Kite Pharma CCO (Yescarta launch) and Pharmacyclics CCO (Imbruvica) .

Past Roles

OrganizationRoleTenureCommittees/Impact
CoRegen, Inc. (private)Chief Executive OfficerJan 2025 – Apr 2025CEO of private company; brief tenure disclosed in 2025 proxy
Kite PharmaChief Commercial Officer2015 – 2018Led global commercialization of Yescarta; spanned Gilead’s $11.9B acquisition (Oct 2017)
PharmacyclicsChief Commercial OfficerAug 2014 – Aug 2015Led commercial & medical affairs for Imbruvica; across AbbVie’s $21.0B acquisition (Aug 2015)
CelgenePresident, Americas Hematology & OncologyPrior to 2014Five successful product launches across 11 indications; role in acquisitions
GenentechNational Director of Hematology (Rituxan)~14 years (prior to Celgene)National commercial leadership for Rituxan

External Roles

CompanyRoleTenureNotes
4D Molecular Therapeutics (NASDAQ: FDMT)DirectorNov 2020 – PresentCurrent public company directorship
Centrexion Therapeutics (private)Director2017 – PresentCurrent private company board
AlloVir (NASDAQ: ALVR)DirectorMar 2022 – Mar 2025Former public board
Gamida Cell (NASDAQ: GMDA)DirectorJun 2019 – 2024Former public board
TCR2 Therapeutics (NASDAQ: TCRR)Director– Jun 2023Former public board
UroGen Pharma (NASDAQ: URGN)Director– 2022Former public board
Mesoblast (NASDAQ: MESO)Director– Aug 2022Former public board
Clementia PharmaceuticalsDirectorn/dFormer public/biopharma board
Diplomat PharmacyDirector– 2020Former public board
Abeona Therapeutics (NASDAQ: ABEO)Director– 2020Former public board
Principia BiopharmaDirector– 2020Former public board
Various private boardsDirector/Committee membern/aService on Compensation, Nominating & Corporate Governance, Compliance, and Transaction committees (various)

Board Governance

  • Independence: Board has determined all directors except the CEO are independent (includes Ms. Tomasello) .
  • Committees: Compensation Committee member (Chair: Mark Simon); Science & Technology Committee member (Chair: Catherine Bollard) .
  • Attendance: In 2024, each director attended 90%+ of board and applicable committee meetings; 9 board meetings held . In 2023, each director attended 75%+; 9 board meetings held .
  • Executive sessions: Independent directors meet in executive session at virtually every board meeting .
  • Lead Independent Director: Not disclosed; Chair and CEO roles combined per governance framework .

Fixed Compensation

ComponentPolicy Detail (2024)Policy Detail (2025)Ms. Tomasello 2024 Actual
Board cash retainer$40,000$40,000Included in fees
Audit Committee (Member/Chair)$7,500 / $15,000$10,000 / $20,000n/a
Compensation Committee (Member/Chair)$5,500 / $11,000$6,250 / $12,500Member ($5,500)
Nominating & Corporate Gov. (Member/Chair)$5,000 / $10,000$5,000 / $10,000n/a
Science & Technology (Member/Chair)$7,500 / $15,000$7,500 / $15,000Member ($7,500)
Total cash fees (2024 actual)$53,000 (Board $40,000 + Comp $5,500 + S&T $7,500)

Notes: No per-meeting fees; cash paid quarterly in arrears .

Performance Compensation

Equity Element2023 Value2024 ValueVesting/StructureNotes
Option awards (grant-date fair value)$486,513$181,810Initial option: 44,000 shares, vests quarterly over 3 years; Annual option: 22,000 shares, vests by next AGM/1-year
Unvested option shares outstanding (12/31/24)47,667Time-based vestingAggregate unvested “shares outstanding” reported for directors
Aggregate options held (12/31/24)66,000Time-basedAggregate option count as of year-end 2024
  • Director equity program: Initial one-time option (44,000) at appointment; annual option (22,000) at each AGM; vesting as above; intended to align directors with shareholders .

Other Directorships & Interlocks

  • Compensation Committee Interlocks: CABA discloses none; no officer/director cross-service interlocks involving CABA executives and Ms. Tomasello .
  • Related-party transactions: None involving directors/executives/5% holders above $120,000 since Jan 1, 2023/2022 (as applicable) .

Expertise & Qualifications

  • Domain expertise: Commercialization of cell/gene therapies and hematology-oncology (Yescarta, Imbruvica); senior roles at Genentech, Celgene, Pharmacyclics, Kite .
  • Education: B.S. (University of Cincinnati); MBA (Murray State University) .
  • Board qualifications: Experience on Compensation, Nominating & Corporate Governance, Compliance, and Transaction committees across public/private biopharma boards .

Equity Ownership

MetricAmountAs-of Date
Total beneficial ownership (shares)47,667Apr 28, 2025
Ownership as % of outstanding0.09%Apr 28, 2025 (outstanding 50,743,101)
Unvested option shares47,667Dec 31, 2024
Aggregate option awards held66,000Dec 31, 2024
Shares pledged as collateralProhibited absent Audit Committee approval (no pledges disclosed)Policy

Policy prohibits short sales, hedging, and pledging without advance Audit Committee approval; 10b5-1 plan governance adopted; no director hedging/pledging disclosures indicated .

Governance Assessment

  • Alignment and incentives: Cash fees modest; equity via options provides long-term alignment. However, small personal stake (0.09%) limits immediate “skin-in-the-game”; unvested options are sizable relative to holdings, driving retention but potentially increasing sensitivity to volatility .
  • Independence and oversight: Independent; serves on Compensation and Science & Technology committees; no interlocks; no related-party transactions; independent comp consultant (Radford) supports committee independence .
  • Engagement: Board/committee attendance strong (≥90% in 2024); independent director executive sessions at virtually every meeting enhance governance .
  • Risk controls: Robust insider trading, anti-hedging/pledging policies; clawback policy adopted in Sept 2023 for executives (broader governance tone) .
  • External load/time commitment: Extensive multi-board history; currently on at least two boards (FDMT, Centrexion). Short CEO stint at a private company in 1H25. No attendance deficiencies disclosed, but ongoing monitoring of commitments advisable in a resource-constrained issuer (CABA disclosed going-concern risk and need for capital in 2025) .

RED FLAGS

  • Low direct ownership (0.09%) vs. equity-heavy option-based compensation; may limit immediate downside alignment .
  • Multiple external roles (public/private) could pose time-commitment risk; mitigate through continued high attendance and transparent committee workload .

Positive Signals

  • Independent; no related-party dealings; strong attendance; service on key committees; significant commercialization expertise in CABA’s modality-adjacent domains .