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Steven Nichtberger

Steven Nichtberger

Chief Executive Officer and President at Cabaletta Bio
CEO
Executive
Board

About Steven Nichtberger

Steven Nichtberger, M.D., is Cabaletta Bio’s President, CEO, and Chairman since founding in 2017; age 63 as of April 28, 2025, with prior leadership roles at Merck and Tengion and academic ties to Wharton/UPenn . Cabaletta is pre-revenue and recorded net losses of $115.86M in 2024 and $67.68M in 2023; TSR for a $100 investment measured from 12/31/2022 was $24.54 in 2024 vs $245.41 in 2023, indicating high volatility during his tenure . He beneficially owns 3,149,413 shares (5.99% of outstanding), aligning incentives with shareholders .

Past Roles

OrganizationRoleYearsStrategic impact
Tengion, Inc.President & CEO; Director2004–2011Led regenerative medicine company; received National Ernst & Young Entrepreneur of the Year (Emerging Companies) in 2008 .
Merck & Co.Head of Global Marketing; various commercial roles1995–2003Senior commercial leadership at large-cap pharma, informing market access and launch strategies .

External Roles

OrganizationRoleYearsNotes
Wharton School, University of PennsylvaniaProfessor of Professional Practice; Adjunct ProfessorNot disclosedAcademic roles in the Vagelos LSM program/Wharton, reinforcing network and domain expertise .
BioAdvance Greenhouse FundBoard MemberNot disclosedVenture/early-stage biotech investment exposure .
Industry/Nonprofit (e.g., Alliance for Regenerative Medicine, Pennsylvania Bio, BIO)Past Director/Chair (various)Not disclosedFounding member/board leadership across sector organizations .

Fixed Compensation

YearBase Salary (paid, $)Target Bonus % of SalaryActual Bonus Paid ($)Option Awards Grant Date FV ($)
2024646,328 55% 428,157 7,008,417
2023597,417 Not disclosed412,288 3,784,529

Additional detail (2024 salary changes): Base moved from $602,200 to $638,300 effective March 1, 2024 .

Performance Compensation

ComponentMetricWeightingTargetActual/PayoutVesting/Timing
Annual Cash Incentive (2024)Company objectives (clinical development, business development, financial/operational goals, team culture) Not disclosedNot disclosedCompany achievement 108%; Individual achievement 114%; Paid $428,157 (CEO) Paid in 2025 for 2024 performance

Notes: The compensation committee uses Radford as independent consultant; program emphasizes market competitiveness and pay-for-performance, but specific quantitative targets/weights were not disclosed .

Equity Ownership & Alignment

ItemDetail
Beneficial ownership3,149,413 shares; 5.99% of outstanding (50,743,101 shares outstanding as of Apr 28, 2025) .
Vested vs unvested (12/31/2024)Options exercisable: 1,569,823; Options unexercisable: 724,119 .
Pledging/HedgingInsider trading policy prohibits short sales, derivative transactions, margin pledging; no waivers requested/approved to date .
Ownership guidelinesNot disclosed for executives (director/exec ownership guidelines not stated) —
Equity plan capacity11,231,148 options outstanding; 1,693,564 shares available across plans as of 12/31/2024 .

Key Option Grants and Vesting (Outstanding at 12/31/2024)

GrantExercisable (#)Unexercisable (#)Exercise Price ($)ExpirationVesting Schedule (summary)
Legacy option (2018)186,4511.0110/28/2028Historical; fully vested .
Legacy option (2018)229,6771.0110/28/202825% at 10/11/2019; monthly thereafter (1).
2019 grant99,71411.0010/23/202925% at 10/24/2020; quarterly thereafter (2).
2020 grant300,00014.942/28/203025% at 3/1/2021; quarterly thereafter (3).
2021 grant312,65620,84411.472/28/203125% at 3/1/2022; quarterly thereafter (7).
2022 grant261,250118,7503.211/17/203225% at 1/18/2023; quarterly thereafter (8).
2023 grant180,075231,52511.091/17/203325% at 1/18/2024; quarterly thereafter (9).
2024 grant353,00023.972/28/203425% at 3/1/2025; quarterly thereafter (10).

Note: Numbers as of 12/31/2024; vesting subject to continued service .

Employment Terms

ScenarioCash SeveranceCOBRAEquity TreatmentOther Key Terms
Termination without cause / for good reason (outside CIC period)12 months base salary Employer-paid premiums up to 12 months No automatic acceleration unless special clause below At-will; base salary/bonus set by Board; life insurance premium reimbursement .
Termination without cause / for good reason (within CIC period: 60 days before to 12 months after CIC)1.5x (base salary + target bonus), paid over 18 months Employer-paid premiums up to 18 months Full acceleration of all stock options and stock-based awards 280G cutback (no excise tax gross-up); benefits reduced if beneficial after-tax .
Special “Chair dissatisfaction” good reason (outside CIC)As above (12 months salary) plus equity accelerationEmployer-paid premiums up to 12 months Full acceleration if resigns within 6 months after a chair is appointed and Board doesn’t change chair after notice Non-compete and non-solicit apply during employment and 12 months post-termination .

Board Governance and Director Service (Dual-Role Implications)

  • Roles: Chairman of the Board and CEO since 2017; not independent due to executive status .
  • Board structure: 6 directors across three staggered classes; independent directors comprise a majority; independent directors meet in executive session regularly .
  • Committees (all independent members):
    • Audit: Henriques (Chair), Brun, Simon; Henriques designated financial expert; met 6 times in 2024 .
    • Compensation: Simon (Chair), Henriques, Tomasello; met 4 times in 2024 .
    • Nominating & Corporate Governance: Brun (Chair), Bollard, Simon; met 2 times in 2024 .
    • Science & Technology: Bollard (Chair), Brun, Tomasello; 4 meetings in 2024 .
  • Attendance: Each director attended ≥90% of board and committee meetings in 2024; 5 of 6 attended the 2024 annual meeting .
  • Director compensation: CEO receives no additional pay for board service; non-employee director cash retainers (2024: Board $40k; committee retainers vary) and annual options; policy updated in 2025 to increase certain committee retainers (e.g., Audit member $10k; Chair $20k) .
  • Dual-role considerations: Board defends combined Chair/CEO structure for unified leadership and accountability; independent committee chairs and regular executive sessions serve as counterbalances .

Related Policies, Controls, and Risk Flags

  • Insider trading/pledging/hedging: Policy prohibits short sales, hedging, derivatives, and pledging/margin use without audit committee approval; no waivers granted to date .
  • Clawback: Dodd-Frank/Nasdaq-compliant compensation recovery policy adopted Sept 12, 2023 for current/former executive officers; recovers excess incentive comp for three years preceding a required restatement .
  • Compensation risk: Company deems programs not likely to encourage excessive risk-taking; emphasizes long-term alignment .
  • Related-party transactions: None exceeding thresholds since Jan 1, 2023 (other than disclosed offerings involving 5% holders); formal related-person transaction policy in place .
  • Say-on-pay: First non-binding advisory Say-on-Pay and Say-on-Frequency votes scheduled for 2025; Board recommends annual frequency .

Director Compensation (Context for Dual Role)

2024 Non-Employee Director FeesMember Annual Retainer ($)Chair Annual Retainer ($)
Board40,000
Audit Committee7,500 15,000
Compensation Committee5,500 11,000
Nominating & Corporate Governance5,000 10,000
Science & Technology7,500 15,000

Note: CEO receives $0 for board service; 2025 committee retainers increased (e.g., Audit member $10k; Chair $20k) .

Performance & Track Record (Company-Level)

YearTSR: $100 initial on 12/31/2022 ($)Net Income (Loss), $M
2023245.41 (67.68)
202424.54 (115.86)

Narrative: As a clinical-stage company with no revenue in 2023–2024, net losses are expected; TSR shows a sharp rise in 2023 followed by a significant decline in 2024, underscoring equity volatility tied to clinical/regulatory catalysts .

Employment Contracts & Severance Economics (Detail)

  • CEO target bonus: 55% of base salary (2024), with company achievement at 108% and individual achievement at 114%; cash incentive paid $428,157 for 2024 .
  • Severance: Outside CIC—12 months base and up to 12 months COBRA; In CIC—1.5x (base + target bonus) over 18 months, 18 months COBRA, and full equity acceleration on qualifying termination; 280G cutback applies; 12-month non-compete/non-solicit post-termination .
  • Special governance safeguard: Unique “chair dissatisfaction” good reason resignation term allowing equity acceleration on resignation if a newly appointed chair is not replaced within 30 days after notice, exercisable within six months of appointment (outside CIC) .

Investment Implications

  • Alignment vs dilution: CEO’s 5.99% beneficial stake is meaningful; however, high option overhang (11.23M options outstanding) and recently authorized share increase request signal ongoing equity financing needs; company disclosed going-concern risk absent additional capital beyond 1H26, increasing dilution risk and potential selling pressure as time-vested options continue to vest .
  • Pay-for-performance: Cash incentives hinge on multi-factor operational goals (clinical, BD, ops), not financial revenue/EBITDA, consistent with clinical-stage status; equity-heavy grants amplify sensitivity to stock volatility; negative “Compensation Actually Paid” in 2024 reflects mark-to-market declines despite higher grant-date values, indicating real mark-to-market alignment but also volatility .
  • Retention vs parachute risk: Strong CIC protection (1.5x base+bonus, full acceleration) balances retention through change but could create take-private/M&A negotiation optics; outside CIC, a 12-month severance and a unique "chair dissatisfaction" clause offer the CEO leverage over board leadership dynamics—an atypical provision that may influence governance perceptions .
  • Governance checks: Combined Chair/CEO raises independence concerns, mitigated by majority-independent board, independent committee chairs, and regular executive sessions; no excise tax gross-ups; robust anti-hedging/pledging and clawback policies reduce governance red flags .