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Diem Nguyen

Director at Candel Therapeutics
Board

About Diem Nguyen

Diem Nguyen, Ph.D., M.B.A., is an independent director of Candel Therapeutics (CADL) who has served on the board since July 2021; she is a Class III director with a term expiring at the 2027 annual meeting and is 53 years old . She is currently the Chief Executive Officer of SIGA Technologies (Nasdaq: SIGA) and brings significant biopharma operating and commercial experience, with prior senior roles at Xalud Therapeutics, PPD, and Pfizer; she holds a B.A. in Chemistry, a Ph.D. in Biochemistry and Molecular Genetics, and an M.B.A. from the University of Virginia/Darden . The board has determined she is independent under Nasdaq and SEC rules .

Past Roles

OrganizationRoleTenureCommittees/Impact
Xalud Therapeutics (PBM Capital majority-owned)Chief Executive Officer and DirectorOct 2020 – Jan 2024Led a private biotech; governance relevance due to PBM Capital tie .
PPD, Inc.Executive Vice PresidentApr 2018 – Apr 2020Senior operating role at a global CRO .
Pfizer Inc.Various leadership roles; Global President, Americas, Pfizer Essential Health (last role)2008 – Mar 2018 (Global President, Americas Jan 2017 – Mar 2018)Large-cap biopharma operating/commercial experience .

External Roles

OrganizationRoleTenureNotes/Interlocks
SIGA Technologies (Nasdaq: SIGA)Chief Executive OfficerSince Jan 2024Current public-company CEO role .
Verrica Pharmaceuticals (Nasdaq: VRCA)DirectorCurrentInterlock: Paul B. Manning (CADL director) is Chairman of Verrica; both sit on Verrica board .
Vitara Biomedical, Inc.DirectorCurrentPrivate company board .
Children’s Hospital of PhiladelphiaDirectorCurrentNon-profit board .

Board Governance

  • Independence: The board has determined all directors other than the CEO are independent; this includes Dr. Nguyen .
  • Board structure: Classified board (3 classes). Dr. Nguyen is Class III (term ends 2027) .
  • Committees (2024–2025):
    • Audit Committee: Member; audit committee met 4 times in 2024; committee is fully independent; chair is Christopher Martell; audit committee financial expert is Renee Gaeta .
    • Compensation Committee: Member during fiscal 2024 (with Paul B. Manning and Joseph C. Papa); the committee met 3 times in 2024. Composition changed for 2025 to Loggia (Chair), Manning, and Papa .
    • Nominating & Corporate Governance: Dr. Nguyen is not listed as a member; committee met once in 2024 .
  • Attendance: The full board met 16 times in 2024; each director attended at least 75% of combined board and committee meetings during their service period in 2024 .
  • Executive sessions/lead independent director: Not disclosed in the proxy excerpts provided.

Fixed Compensation

ComponentAmount ($)Notes
Fees Earned or Paid in Cash (2024)47,500Actual fees per 2024 Director Compensation Table .
Board annual retainer (policy)35,000Policy amount for all non-employee directors .
Audit Committee member (policy)7,500Policy amount; aligns with 2024 audit membership .
Compensation Committee member (policy)5,000Policy amount; aligns with 2024 membership .

The sum of policy retainers ($35k + $7.5k + $5k) matches Dr. Nguyen’s 2024 cash fee of $47.5k, corroborating committee assignments .

Performance Compensation

Equity Element2024 Grant or HoldingTerms/Notes
Option Awards (2024, grant-date fair value)$68,405Aggregate grant-date fair value computed per ASC 718 .
Outstanding stock options at 12/31/202456,960 optionsUnexercised stock options held as of year-end 2024 .
Initial director equity (policy)28,480 optionsVests in equal monthly installments over 3 years from grant date .
Annual director equity (policy)14,240 optionsVests in full at earlier of 1-year anniversary or next annual meeting, subject to service .

Compensation consultant: The Compensation Committee engages Radford (Aon) and assessed no conflicts of interest .

Other Directorships & Interlocks

  • Verrica Pharmaceuticals (VRCA): Dr. Nguyen serves as a director; Paul B. Manning (CADL director) is Chairman of Verrica—creating a board interlock that can facilitate information flow but warrants monitoring for potential conflicts if any transactions arise between related entities .
  • PBM Capital connections: Dr. Nguyen previously led Xalud Therapeutics, a PBM Capital majority-owned company; Paul B. Manning is CEO of PBM Capital and a director of CADL, representing another network linkage (no specific CADL related-party transaction disclosed) .

Expertise & Qualifications

  • Education: B.A. in Chemistry (Biochemistry specialization), Ph.D. in Biochemistry and Molecular Genetics, and M.B.A. in General Management (all University of Virginia/Darden) .
  • Domain expertise: Extensive pharmaceutical and biotech operating and commercial leadership at Pfizer, PPD, Xalud, and SIGA; relevant to oversight of clinical, regulatory, and commercialization strategies .

Equity Ownership

HolderShares Beneficially Owned% OutstandingNotes
Diem Nguyen, Ph.D., M.B.A.81,200<1%As of April 21, 2025; includes shares acquirable within 60 days per SEC rules .
Unexercised stock options (12/31/2024)56,960Option count per director holdings table .
  • Hedging/derivatives/short sales: Company policy expressly prohibits short sales and derivative/hedging transactions for directors, officers, and employees; the policy discusses risks associated with margin/pledged securities but the prohibition specified applies to short sales and hedging/derivative transactions .
  • Pledging: No pledging disclosure specific to Dr. Nguyen; policy notes risks of pledged or margined securities generally .

Governance Assessment

  • Positives

    • Independent director with multi-committee exposure; currently on Audit (4 meetings in 2024) and served on Compensation during 2024, enhancing oversight breadth .
    • Solid engagement: Board met 16 times in 2024; all directors, including Dr. Nguyen, attended at least 75% of combined board/committee meetings .
    • Strong operating background (current SIGA CEO; prior PPD/Pfizer senior roles) supports board effectiveness in clinical/commercial governance .
    • Director pay is modest and primarily at-risk via options; cash fees align with published retainers and committee roles, indicating standard, non-excessive director pay practice .
    • Compensation Committee uses independent consultant (Radford) with no identified conflicts; supports sound pay governance .
    • Board affirms director independence (other than CEO), including committee independence; Audit designates a financial expert (Gaeta) .
  • Watch items / potential red flags

    • Network interlocks: Overlap via Verrica board with Paul B. Manning and prior leadership at PBM Capital–owned Xalud while Manning is PBM Capital CEO and CADL director; while no related-party transactions are disclosed and independence is affirmed, these ties warrant monitoring for perceived conflicts should any transactions arise involving PBM-affiliated entities .
    • Committee rotation: Dr. Nguyen was on Compensation Committee in 2024, but not listed for 2025; investors may ask about rationale and continuity in compensation oversight, though the committee remained independent and met 3 times in 2024 .
    • Hedging policy is strong (prohibits short sales/derivatives/hedging), but pledging is discussed as a risk rather than explicitly prohibited in the quoted policy language; lack of explicit pledging ban can be a governance preference consideration for some investors .
  • Disclosures with no identified issues

    • Legal proceedings: None material for directors, including Dr. Nguyen, as disclosed .
    • Related-party transactions: Policy requires Audit Committee approval; no Dr. Nguyen–specific related-party transactions disclosed in the provided excerpts .
    • Say-on-pay results, director ownership guidelines, and insider Form 4 activity: Not disclosed in the provided excerpts; no claims made.