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Edward Benz Jr.

Director at Candel Therapeutics
Board

About Edward J. Benz, Jr.

Edward J. Benz, Jr., M.D., age 78 as of April 29, 2025, has served on Candel Therapeutics’ board since September 2017 and is a Class II director with a term expiring at the 2026 annual meeting . A hematologist and internal medicine specialist, he is President and CEO Emeritus of the Dana-Farber Cancer Institute, a Harvard Medical School professor, and Executive Director of the NIH Cure Sickle Cell Initiative, with 300+ publications and multiple professional society presidencies, underscoring deep domain expertise in blood disorders and translational medicine .

Past Roles

OrganizationRoleTenureCommittees/Impact
Dana-Farber Cancer InstitutePresident & CEO; later President & CEO EmeritusOct 2000 – Oct 2016 (President & CEO); Emeritus thereafterLed one of the leading oncology centers, broad executive leadership in research and clinical operations
Harvard Medical SchoolRichard & Susan Smith Distinguished Professor of Medicine; Professor of Pediatrics and GeneticsOngoingAcademic leadership; research and teaching in hematology/genetics
Johns Hopkins University & HospitalChair, Dept. of Medicine; Sir William Osler Professor; Physician-in-ChiefPrior to Dana-Farber tenureOversaw medical department operations and clinical excellence
Professional Societies (ASH, AACI, ASCI, ACCS, Friends of NINR)PresidentVariousNational leadership across hematology and clinical research communities

External Roles

OrganizationRoleStatusNotes
CoRegen, Inc.DirectorCurrentPrivate company board service
Autoimmunity Biological SolutionsScientific Advisory BoardCurrentPrivate SAB
MYKA Labs, Inc.Scientific Advisory BoardCurrentPrivate SAB
Kernal Biologics, Inc.Scientific Advisory BoardCurrentPrivate SAB
Deciphera Pharmaceuticals (Nasdaq: DCPH)DirectorPriorPublic company; oncology focus
F-Star Therapeutics (formerly Nasdaq: FSTX)DirectorPriorPublic biotech; antibody engineering
Renovacor (formerly NYSE: RCOR)DirectorPriorPublic biotech; cardiovascular gene therapy
Xenetic Bioscience (Nasdaq: XBIO)DirectorPriorPublic biotech

No related-person transactions involving Dr. Benz are mentioned in the provided proxy excerpts; the audit committee reviews and must approve any related party transactions >$120,000 under written policy .

Board Governance

AttributeDetail
Committee AssignmentsNominating & Corporate Governance Committee (Chair); members include Benz, Loggia, Martell, Nabel
IndependenceBoard determined all members of Nominating & Governance are independent under Nasdaq rules
Committee Activity (2024)Nominating & Governance met 1 time in 2024
Board Meetings (2024)Full board met 16 times
AttendanceEach director attended ≥75% of aggregate board and committee meetings during periods served in 2024
Lead Independent DirectorNot disclosed in proxy excerpt
Executive SessionsNot disclosed in proxy excerpt

Fixed Compensation

Component2024 AmountNotes
Fees Earned or Paid in Cash$43,000 Matches board retainer ($35,000) plus Nominating & Governance chair fee ($8,000) per policy
Annual Board Retainer (Policy)$35,000 For all non-employee directors
Nominating & Governance Chair Fee (Policy)$8,000 Applies to Benz as chair
Meeting FeesNone disclosed Policy does not include per-meeting fees

Performance Compensation

Component2024 DetailVesting / Terms
Option Awards (Grant-date fair value)$68,405 Annual non-qualified stock option grant per policy; fair value under FASB ASC 718
Annual Option Share Count (Policy)14,240 shares Vests fully upon earlier of 1-year anniversary or next annual meeting, subject to service
Initial Option Grant (Policy)28,480 shares Vests in equal monthly installments over 3 years from grant, subject to service
Unexercised Options Outstanding (12/31/2024)97,644 shares Aggregate outstanding options held as of year-end 2024
Exercise Price / ExpirationNot disclosed in proxy tablePolicy indicates grants at then fair market value; specific strike/expiry not provided

Policy does not disclose performance metrics (e.g., TSR/EBITDA) for director equity; director equity is options with time/service-based vesting .

Other Directorships & Interlocks

CompanyMarketRolePotential Interlock/Conflict
CoRegen, Inc.PrivateDirectorNo CADL-related transactions disclosed in proxy excerpts
Deciphera (DCPH), F-Star (FSTX), Renovacor (RCOR), Xenetic (XBIO)PublicPrior DirectorBiotech network relevance; no CADL-related transactions disclosed in proxy excerpts

Expertise & Qualifications

  • Board-certified in hematology and internal medicine; recognized expert in blood disorders .
  • Senior academic leadership at Harvard Medical School; extensive publication record (300+ articles, books, reviews, abstracts) .
  • Former President & CEO of Dana-Farber; former department chair and physician-in-chief at Johns Hopkins—adds large-institution governance and clinical operations experience .
  • NIH leadership (Executive Director, Cure Sickle Cell Initiative) underscores government/research interface expertise .

Equity Ownership

ItemAmountNotes
Beneficial Ownership (as of 4/21/2025)111,884 shares Less than 1% of outstanding shares (49,269,668)
Composition of Beneficial Ownership111,884 shares issuable upon exercise of options exercisable within 60 days Indicates beneficial holding primarily via vested options
Unexercised Options (12/31/2024)97,644 shares Outstanding options at year-end 2024
Hedging/Pledging PolicyCompany policy prohibits short sales and derivative/hedging transactions by directors; warns of risks from margin/pledged shares

Governance Assessment

  • Board effectiveness: Benz chairs the Nominating & Governance Committee and is deemed independent under Nasdaq rules; however, that committee met only once in 2024—consider monitoring cadence vs. governance workload as the company evolves .
  • Independence and engagement: He met the ≥75% attendance threshold amid 16 board meetings in 2024, indicating baseline engagement; age and deep domain background add value on science/clinical oversight .
  • Compensation mix and alignment: Director pay skews toward equity via options (2024 fair value $68,405 vs. $43,000 cash), consistent with alignment practices, but beneficial ownership appears limited to options (no disclosed direct share holdings)—moderate “skin-in-the-game” signal reliant on option value .
  • Conflicts and related-party exposure: No related-person transactions involving Benz are mentioned in the provided proxy excerpts; the audit committee must pre-approve any such transactions >$120,000 under the written policy, mitigating conflict risk .
  • RED FLAGS: Limited disclosed director equity beyond options (beneficial ownership comprised of exercisable options) may be viewed as weaker direct ownership alignment; Nominating & Governance’s single meeting in 2024 could be scrutinized relative to governance best practices in active biotech contexts .