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Nicoletta Loggia

Director at Candel Therapeutics
Board

About Nicoletta Loggia

Independent Class III director at Candel Therapeutics (since June 2023; age 57; term expires at the 2027 annual meeting). Chief Technical Officer of Orchard Therapeutics plc (Nasdaq: ORTX) since September 2021; previously held senior global technical development leadership roles at Novartis (2015–2021) and earlier scientific roles at Pfizer. Ph.D. and master’s in Pharmaceutical Technologies from the University of Pavia; accreditation from EPFL’s Startup Board Member Academy. Beneficial ownership at Candel is less than 1% of shares outstanding .

Past Roles

OrganizationRoleTenureCommittees/Impact
Novartis AGGlobal Head, Cell & Gene TherapiesApr 2020–Aug 2021Led CGT technical functions
Novartis AGGlobal Head, Technical Development Biologics & Cell Gene TherapiesJan 2019–Apr 2020Global technical development leadership
Novartis AGGlobal Head, Technical Development of Novel Biologic Entities & Early Phase Project Management2015–Dec 2018Early-phase program oversight
PfizerFormulation Senior/Principal ScientistEarlier careerR&D/formulation roles

External Roles

OrganizationRoleTenureCommittees/Impact
Orchard Therapeutics plc (ORTX)Chief Technical OfficerSep 2021–presentExecutive leadership in CGT
Sarcura GmbHAdvisory Board MemberMay 2022–presentAdvisory position

Board Governance

  • Independence: Board determined all directors except the CEO are independent; Dr. Loggia is independent under Nasdaq/SEC rules .
  • Committee assignments: Chair, Compensation Committee; member, Nominating & Corporate Governance Committee .
  • Board leadership: Board chaired by Paul B. Manning (non-executive chair) .
  • Attendance: Board met 16 times in 2024; each director attended at least 75% of board and applicable committee meetings (Comp Committee met 3 times; Nominating & Governance met 1 time) .
  • Compensation consultant: Radford engaged; Compensation Committee assessed independence and found no conflict of interest .
  • Clawback: Company maintains a compensation recovery (clawback) policy consistent with SEC/Nasdaq rules .
  • Insider trading policy: Prohibits short sales, derivatives, and hedging in company securities by directors/officers/employees .
  • EGC status: As an emerging growth company, Candel is not required to conduct say‑on‑pay votes .

Fixed Compensation

Item2024Notes
Fees Earned or Paid in Cash ($)$41,264 Actual cash paid in 2024
Board Annual Retainer (Policy) ($)$35,000 Applies to all non‑employee directors
Compensation Committee Chair Fee (Policy) ($)$10,000 As committee chair
Nominating & Governance Committee Member Fee (Policy) ($)$4,000 As committee member

Candel does not disclose meeting fees; policy fees may be prorated based on service dates .

Performance Compensation

ComponentMetric/Structure2024 ValueVesting
Option Awards (Fair Value)ASC 718 grant-date fair value ($)$68,405 Per grant terms (see below)
Annual Director Option Grant SizeShares14,240 Vests fully on the earlier of first anniversary or next annual meeting, subject to service
Initial Director Option Grant (new directors)Shares28,480 (policy) Vests in equal monthly installments over 3 years, subject to service
Unexercised Options Outstanding (12/31/2024)Shares14,240

Candel did not disclose performance conditions for director equity; director options vest time‑based per policy (no TSR/financial metrics) .

Other Directorships & Interlocks

CompanyRolePublic/PrivateOverlap/Notes
Orchard Therapeutics plc (ORTX)Chief Technical OfficerPublicExecutive role; no related‑party transactions disclosed in proxy
Sarcura GmbHAdvisory Board MemberPrivateAdvisory role

Expertise & Qualifications

  • Deep biopharmaceutical manufacturing and technical operations experience across cell and gene therapies; senior global technical development leadership at Novartis; formulation science background at Pfizer .
  • Academic credentials: Ph.D. and master’s in Pharmaceutical Technologies (University of Pavia); EPFL Startup Board Member Academy accreditation .

Equity Ownership

MetricValueNotes
Beneficial Ownership (Shares)33,226 Less than 1% of outstanding shares
CompositionOptions exercisable within 60 daysAll 33,226 are options exercisable within 60 days after 4/21/2025
Shares Outstanding (Record Date)49,269,668 As of April 21, 2025

Additional data: Unexercised options outstanding as of 12/31/2024 were 14,240 . Hedging/derivative transactions are prohibited for directors .

Governance Assessment

  • Positives: Independent director; chairs Compensation Committee; presence on Nominating & Governance Committee—positions that influence pay structures and board composition . Use of an independent compensation consultant and adoption of clawback and anti‑hedging policies support governance quality .
  • Alignment: Ownership is modest (<1% of common stock) and primarily via options; ongoing annual option grants and initial option grant structure provide some alignment but are time‑based (no disclosed performance metrics) .
  • Engagement: Board met 16 times; directors met the ≥75% attendance threshold; Compensation Committee met 3 times—indicative of regular committee activity .
  • Watch items: Concurrent executive responsibilities at ORTX (a public CGT company) may create potential time‑commitment or industry‑overlap considerations; the proxy discloses no related‑party transactions involving Dr. Loggia, and the company has an audit committee review policy for any such transactions . As an EGC, the lack of say‑on‑pay votes reduces direct shareholder feedback on compensation design .