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Paul B. Manning

Chair of the Board at Candel Therapeutics
Board

About Paul B. Manning

Independent director (Class II) at Candel Therapeutics (CADL) since 2018; currently Chair of the Board. Age 69 as of April 29, 2025; B.S. in Microbiology from the University of Massachusetts; 30+ years operating and investing experience in healthcare as CEO of PBM Capital Group, LLC (founded 2010) .

Past Roles

OrganizationRoleTenureCommittees/Impact
PBM Capital Group, LLCChief Executive Officer2010–presentFounder of healthcare/life-sciences PE; influences boardroom perspective on capital allocation and biotech governance .
AveXis, Inc.Director2014–2018Gene therapy board experience; pre-acquisition strategic oversight .
Dova Pharmaceuticals, Inc.Director2016–2019Biopharma governance and M&A transition experience .

External Roles

OrganizationRoleTenureNotes / Interlocks
Verrica Pharmaceuticals (VRCA)Chairman of the BoardCurrentInterlock: Candel director Diem Nguyen also serves on Verrica’s board, indicating information flow/network overlap .
Liquidia Corporation (LQDA)DirectorCurrentPulmonary drug delivery; capital markets and regulatory exposure .
Taysha Gene Therapies (TSHA)DirectorCurrentGene therapy expertise; clinical development oversight .

Board Governance

  • Status: Independent director under Nasdaq and SEC rules; board determined all non-employee directors (including Manning) are independent; CEO Paul Peter Tak is not independent .
  • Board leadership: Manning is Chair of the Board; CEO and Chair roles are separated, enhancing oversight .
  • Committee assignments:
    • Compensation Committee: Member; chaired by Nicoletta Loggia; met 3 times in FY2024 .
    • Audit Committee: Not a member; audit met 4 times in FY2024 .
    • Nominating & Corporate Governance Committee: Not a member; committee met once in FY2024 .
  • Attendance: Board met 16 times in 2024; each director attended or participated in ≥75% of aggregate board and relevant committee meetings .

Fixed Compensation

Metric20232024
Cash Fees (Retainer + Chair + Committee) ($)$70,000 $70,000
Policy components (annual)Board retainer: $35,000; Non-executive chair add’l: $30,000; Compensation Committee member: $5,000 (illustrative member fees); aligns to $70,000 total

Policy detail: Non-employee director fees per policy—Board: $35,000; Chair add’l: $30,000; Audit: Chair $15,000/Members $7,500; Compensation: Chair $10,000/Members $5,000; Nominating: Chair $8,000/Members $4,000 .

Performance Compensation

Equity Award StructureGrant SizeVestingValuation Indicator
Initial non-employee director option28,480 optionsMonthly over 3 yearsFair market value at grant; ASC 718 accounting
Annual non-employee director option14,240 optionsVests at earlier of 1-year anniversary or next annual meetingFair market value at grant; ASC 718 accounting
2024 Option Award (fair value)$68,405 (Manning)

No performance-linked metrics (TSR/EBITDA/ESG) disclosed for director equity; awards are time-based options under the non-employee director policy .

Other Directorships & Interlocks

CounterpartyTypeInterlock/OverlapPotential Conflict Consideration
Verrica Pharmaceuticals (VRCA)Customer/Supplier/Peer: BiopharmaManning (Chair) and Diem Nguyen (Candel director) both on VRCA boardNetwork interlock could influence information flow; independence maintained per board determination .
PBM Capital portfolio linksInvestorMartell previously Partner at PBM Capital; Nguyen previously CEO of PBM majority-owned Xalud TherapeuticsMultiple PBM-affiliated relationships on Candel’s board; audit/related party policy in place .

Expertise & Qualifications

  • Healthcare investing/operator experience; 30-year track record in life sciences, capital formation, portfolio governance .
  • Microbiology academic background; biotech domain fluency .
  • Chair experience across public biopharma boards; compensation oversight experience as Candel Compensation Committee member .

Equity Ownership

As of April 21, 2025Shares% of Outstanding
Paul B. Manning total beneficial ownership5,366,03610.6%
Breakdown (footnote)AmountNotes
Paul & Diane Manning (JTWROS)1,681,000Direct common
Paul B. Manning Revocable Trust1,142,406 common + 642,406 warrantsWarrants exercisable within 60 days of 12/31/2021 (legacy footnote context)
BKB Growth Investments, LLC1,303,752 common + 553,752 warrantsManning co-manager of Tiger Lily Capital, manager of BKB; shared voting/disposition
Options exercisable within 60 days (as of 4/21/2025)42,720Director options within 60 days
Non-employee director options outstanding (12/31/2024)28,480Year-end outstanding option count
  • Ownership guidelines/pledging: No director ownership guidelines disclosed; company insider trading policy prohibits short sales and derivative hedging; pledging discussed as risk but not explicitly prohibited; no pledging by Manning disclosed .

Governance Assessment

  • Strengths: Independent chair structure with CEO/Chair separation supports oversight ; Manning independent under Nasdaq/SEC rules ; board/committee activity robust in 2024 (board 16 meetings; compensation met 3x; audit 4x; nominating 1x) with ≥75% attendance .
  • Alignment: Significant ownership (10.6%) aligns interests with shareholders; option-based director equity vests over time, promoting continuity .
  • Controls/Policies: Independent compensation consultant (Radford) engaged; committee assessed consultant independence; clawback policy compliant with SEC/Nasdaq (3-year lookback on restatements) .
  • Watch Items and potential conflicts (highlight for monitoring): PBM-linked interlocks—Manning (PBM Capital CEO), Martell previously PBM Partner, Nguyen prior CEO of a PBM majority-owned company—may increase influence concentration; however, board independence affirmed and related-party transaction policy assigns audit committee pre-approval/oversight .
  • Director pay mix: As Chair, Manning’s cash fees align precisely with policy (Board retainer $35k + Chair $30k + Committee $5k); equity awards shifted materially YoY ($13,186 in 2023 to $68,405 in 2024), driven by grant valuation/structure under policy—monitor consistency vs peers for pay inflation .
  • Hedging/Pledging: Hedging prohibited; no pledging disclosed—maintain oversight given large stake and warrant holdings .

No related-party transactions with Manning reported for 2023–2024 in the proxy’s “Certain Relationships and Related Party Transactions”; policy requires audit committee approval for any such transactions >$120,000 .