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Robert Etherington

Robert Etherington

Chief Executive Officer at CleneClene
CEO
Executive
Board

About Robert Etherington

Robert Etherington is President, Chief Executive Officer, and Director of Clene Inc. (Class III director), roles he has held since April 2013; he is 58 years old and has over 30 years of biopharma commercialization experience . He holds a B.S. in business with a pharmaceutical emphasis and an MBA from Brigham Young University, and completed the General Management Program at Harvard University . Pay-versus-performance disclosures show a value of initial fixed $100 investment (TSR proxy) of $6.48 in 2024, $7.23 in 2023, and $24.39 in 2022, alongside net losses of $39.4 million (2024), $49.5 million (2023), and $29.9 million (2022), framing the operating backdrop during his tenure .

Past Roles

OrganizationRoleYearsStrategic Impact
Parke-Davis (Pfizer)Sales and marketing roles; Team Leader over LipitorPrior to 2000Commercial leadership on major drug franchise (Lipitor)
Actelion PharmaceuticalsFounding Director of Marketing; roles of increasing responsibility in cardiopulmonary disease2000–2017Helped build EU’s largest biopharma pre-J&J acquisition

External Roles

OrganizationRoleYearsStrategic Impact
BioUtahBoard member incl. Vice-Chair, Chairman, Executive Chair2016–2023Industry advocacy and ecosystem leadership in Utah life sciences
Corsair LLC (private biotech)DirectorSince 2018External governance and strategic input to private biotech

Fixed Compensation

YearBase Salary ($)Target Bonus (% of Salary)Actual Bonus ($)All Other Compensation ($)Notes
2024629,160 50% (per employment agreement) 314,580 (earned; payment contingent on funding) 38,348 (incl. $4,500 401k match; health/life/disability) Base most recently adjusted June 2023 to $629,160
2023654,280 50% (per employment agreement) 368,000 (earned; payment contingent on funding) 37,030 401(k) match up to $4,500/year; plan match 100% up to 3% of comp

Employment Agreement (Feb 1, 2022): base salary initially $560,000; annual incentive bonus targeted at 50% of base, determined by Board/Compensation Committee .

Performance Compensation

Annual Incentive (Cash)

  • Structure: Target bonus 50% of base salary; specific performance objectives set annually by Board/Comp Committee (metrics not itemized in proxy) .
  • 2024/2023 outcome: Bonuses earned ($314,580 in 2024; $368,000 in 2023) but not paid due to cost-saving initiatives; payment subject to ability to raise funding .

Long-Term Incentive (Equity) – Outstanding Option Awards (as of 12/31/2024)

Grant DateExercisableUnexercisableExercise Price ($)ExpirationVesting Detail
11/23/201521,434 10.60 11/22/2025 Standard (see plan)
4/30/202127,501 2,499 180.00 4/30/2031 Standard 4-yr (25% at 1-yr, then monthly)
11/4/20213,856 1,144 94.80 11/4/2031 Standard 4-yr
2/15/20223,483 60.80 2/15/2032 Vested in full at grant
2/15/202217,000 7,000 60.80 2/15/2032 Standard 4-yr
11/4/202210,418 9,582 22.20 11/4/2032 Standard 4-yr
6/29/202316,874 28,125 18.00 6/28/2033 Standard 4-yr
6/7/202445,000 7.40 6/6/2034 Standard 4-yr unless specified
6/7/2024 (Performance)112,500 7.40 6/6/2034 33.3% vests on FDA NDA acceptance; 33.3% on FDA NDA approval; 33.4% on $100m revenue from approved drug sales
8/16/20248,333 16,667 5.15 8/15/2034 12 equal installments on 16th of each month starting 9/16/2024
  • General vesting standard for options (unless otherwise noted): 25% on first anniversary, remaining in 36 equal monthly installments; options typically 10-year term .
  • Acceleration: Unexercised options subject to acceleration per severance agreements (see Employment Terms) .

Pay Versus Performance (Context)

YearPEO Total Comp (SCT) ($)PEO Compensation Actually Paid ($)Average Non-PEO NEO SCT ($)Average Non-PEO NEO CAP ($)TSR Value of $100Net Loss ($000s)
20241,367,727 1,771,799 919,593 1,138,902 6.48 (39,400)
20231,706,605 663,354 1,185,840 490,886 7.23 (49,504)
20222,181,629 (366,670) 1,059,931 34,102 24.39 (29,918)

Equity Ownership & Alignment

HolderBeneficial Ownership (Shares)% of OutstandingBreakdown / Notes
Robert Etherington182,702 2.1% Includes 130,667 options exercisable within 60 days of 3/25/2025; 10,000 warrants exercisable within 60 days; 636 shares via RDE RX Ventures, LLC; 1,250 shares via Etherington Revocable Trust; Etherington is manager/trustee of these entities . Company had 8,596,063 shares outstanding as of 3/25/2025 .
  • Hedging/Pledging: Company policy strongly discourages directors and executive officers from hedging transactions; option transfer restrictions in Stock Plan prohibit pledging/hypothecation of options in certain circumstances under Rule 12h-1(f) conditions .

Employment Terms

TermProvision
AgreementEmployment agreement dated Feb 1, 2022 (“Etherington Agreement”)
Base salary$560,000 initially; most recent adjustment June 2023 to $629,160
Target bonus50% of base salary; objectives set by Board/Comp Committee annually
Severance – Without Cause / Good Reason1x base salary; bonus equal to 100% of actual bonus that would have been earned for a period similar to base; acceleration of all outstanding and unvested equity; COBRA reimbursement, subject to release
Severance – Change in Control (30 days before to 12 months after), Without Cause / Good Reason2x base salary and target bonus (plus other Additional Termination Amounts including equity acceleration/COBRA), subject to release; double-trigger window
“Good Reason” definitionIncludes salary reduction (unless company-wide), material breach, material adverse change in duties/title, unpaid amounts, failure by successor to assume agreement, relocation >50 miles or >50 nights travel, bonus eligibility reduction, assignment of inconsistent duties; with notice and cure provisions
BenefitsEligible for company benefit plans; 401(k) match 100% up to 3% of comp, capped at $4,500 per year

Board Governance and Service

  • Role: President, CEO, and Director; Class III director continuing in office until 2026 annual meeting; Director since 2013; not independent .
  • Board leadership: Independent non-employee director serves as Chairman of the Board; committee memberships comprised solely of independent directors . Chairman is David J. Matlin (Class II; Chair of Nominating & Corporate Governance Committee) .
  • Committee participation: Etherington is not listed as a member of Audit, Compensation, or Nominating committees (all independent) .
  • Board activity: Board met nine times in 2024; all directors serving in 2024 attended or participated in ≥75% of meetings; eight directors attended 2024 annual meeting .

Director Compensation (Policy context for non-employee directors)

ComponentNon-Employee Director Policy
Annual meeting grantOptions for 30,000 shares; monthly vesting over 12 months; fully vests at next AGM or change in control
Quarterly retainers (stock options, fully exercisable at grant)Board member $10,000/qtr; Non-exec Chair $17,500/qtr; Audit member $1,875/qtr (Chair $3,750/qtr); Compensation member $1,500/qtr (Chair $3,000/qtr); Nominating member $1,000/qtr (Chair $2,000/qtr)
New director grantOptions for 45,000 shares; 36 equal monthly installments

Compensation Structure Analysis

  • Mix and at-risk pay: CEO compensation relies heavily on stock options, including performance-conditioned tranches tied to FDA NDA acceptance/approval and $100m revenue, aligning upside to value-creation milestones . Cash bonuses for 2023–2024 were earned but withheld pending financing, indicating liquidity discipline but potential retention pressure from deferred cash comp .
  • Equity program intensity: Three-year average burn rate 10.19% with 2024 burn 14.03%; potential overhang estimated at 23.0% (28.1% if plan amendment approved), reflecting heavy option-based incentives to retain talent through regulatory milestones .
  • Governance safeguards: Independent chair and all-independent committees; external consultant FW Cook retained by Compensation Committee; no compensation committee interlocks .

Risk Indicators & Red Flags

  • Deferred cash bonuses (earned but unpaid) increase near-term retention risk and could influence executive liquidity needs around vest dates .
  • High equity overhang and large performance-based grants amplify dilution risk for shareholders but concentrate management incentives on regulatory and commercial inflection points .
  • Hedging strongly discouraged; option pledging restricted under plan conditions, reducing misalignment risk from derivatives/pledging, though explicit executive stock pledging disclosures are not provided in the proxy .

Say-on-Pay & Shareholder Feedback

  • Advisory vote on executive compensation proposed for 2025 meeting; majority of votes cast required; Board recommends “FOR” approval; historical approval percentages not disclosed in this proxy .

Equity Grant Detail – Potential Milestone Levers

  • 6/7/2024 performance option (112,500 shares at $7.40): vests one-third upon NDA acceptance, one-third upon NDA approval, and one-third upon achieving $100m in revenues from approved drug sales, creating clear regulatory/commercial alignment .

Investment Implications

  • Pay-for-performance alignment is strongest around clinical and commercial catalysts: the June 2024 performance options explicitly tie vesting to NDA acceptance/approval and $100m revenue, suggesting meaningful management incentive to achieve near- to mid-term value inflections .
  • Retention risk is non-trivial given unpaid but earned cash bonuses for 2023–2024 and a compensation mix skewed to options; however, single-trigger equity acceleration is included in severance and double-trigger 2x base + target bonus in change-of-control scenarios may stabilize leadership through strategic events .
  • Governance structure mitigates dual-role concerns: Etherington is CEO and director but not Chairman, with an independent chair and fully independent committees overseeing compensation and audit, lowering independence and oversight risk .
  • Ownership alignment exists but is modest by percentage (2.1% including options/warrants within 60 days), with no disclosed pledging; heavy reliance on milestone-based equity creates high sensitivity to FDA and initial commercialization outcomes for CNM-Au8 .