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Brett Kaplan

Chief Operating Officer, Treasurer and Secretary at Climb Bio
Executive

About Brett Kaplan

Brett Kaplan, M.D., is Chief Operating Officer, Treasurer and Secretary of Climb Bio, appointed effective August 26, 2024; he also served as principal financial officer from his appointment until the company designated new PFOs in June and October 2025 as described below . He is 51 years old as of April 25, 2025, and holds an M.B.B.Ch. and an M.B.A. from the University of Witwatersrand . Prior roles include President, Chief Financial and Corporate Development Officer at Chroma Medicine (2021–2024), CFO at Prevail Therapeutics (2018–2021; acquired by Eli Lilly), Managing Director at Evercore (2010–2018), and Equity Research Analyst at Cowen (2007–2010), indicating a blend of operating, corporate finance, and capital markets expertise . Performance metrics such as TSR, revenue growth, and EBITDA growth tied to his tenure are not disclosed in the proxy .

Past Roles

OrganizationRoleYearsStrategic Impact
Chroma Medicine, Inc.President, Chief Financial and Corporate Development OfficerJun 2021 – Aug 2024Senior executive across finance and BD at a private biotech
Prevail Therapeutics Inc.Chief Financial OfficerNov 2018 – Mar 2021CFO at a clinical-stage gene therapy firm acquired by Eli Lilly
Evercore PartnersInvestment Banking, Managing Director (most recent)Aug 2010 – Nov 2018Led banking engagements; capital markets and M&A exposure
Cowen and Company LLCEquity Research AnalystFeb 2007 – Jul 2010Sell-side coverage, analytics foundation

External Roles

OrganizationRoleYearsStrategic Impact
Myeloid Therapeutics, Inc. (private)DirectorSince Jun 2022External network and immunology exposure
Compass Therapeutics, Inc.DirectorSep 2020 – Feb 2022Public biotech board experience

Fixed Compensation

Metric20242025
Base salary earned ($)176,282
Base salary (annualized rate) ($)500,000 515,000 (effective Jan 1, 2025)
Target bonus (% of base)45% 45%
Actual bonus paid ($)79,327 (pro-rated)

Performance Compensation

  • The company awards annual cash bonuses based on board assessment of corporate goals; specific metrics/weightings were not disclosed for 2024 .

Annual Cash Bonus

Element2024
Metric(s)Corporate goals (not itemized)
WeightingNot disclosed
Target45% of 2024 base salary earned (pro-rated)
Actual payout$79,327
VestingN/A (cash)

Equity Awards (New-Hire Grants in 2024)

Award TypeGrant DateShares/UnitsExercise PriceFair Value ($)VestingExpiration
Stock OptionAug 26, 2024465,000 5.95 2,272,734 25% at 1st anniversary; then monthly over 36 months, service-based 08/25/2034
RSUsAug 26, 202477,500 461,125 25% annually on each of the first four anniversaries, service-based

Notes

  • Equity plan uses FMV strike on grant date; options are service-based; full acceleration for time-based awards on double-trigger in change-of-control scenarios per offer letter .

Equity Ownership & Alignment

Ownership Item (as of stated date)Amount
Beneficial ownership (Mar 31, 2025)— shares; less than 1% of outstanding
Shares outstanding denominator (Mar 31, 2025)67,575,767
Options exercisable (Dec 31, 2024)0
Options unexercisable (Dec 31, 2024)465,000
RSUs unvested (Dec 31, 2024)77,500
Market value of RSUs at 12/31/24 close$139,500

Policy alignment:

  • No formal executive stock ownership guidelines; company relies on time-based equity for alignment/retention .
  • Insider Trading Policy prohibits short sales, options and derivatives on company stock, and other hedging transactions; policy filed as an exhibit to the 10-K .
  • Clawback policy (Rule 10D-1 compliant) effective October 2, 2023, applies to current and former executive officers, regardless of fault, upon a restatement .
  • Pledging policy: no explicit pledge prohibition disclosed in the cited sections .

Vesting cadence and potential selling pressure:

  • Options: 25% cliff on Aug 26, 2025; remaining 36 months monthly thereafter, service-based .
  • RSUs: 25% per year on Aug 26 of each year over four years, service-based .

Employment Terms

ProvisionBase Case (non-CoC)Change in Control (double-trigger)
Cash severance9 months base salary; plus any unpaid prior-year annual bonus, lump sum 12 months base salary; target annual bonus for year of termination; any unpaid prior-year annual bonus, lump sum
COBRAUp to 9 months of employer-paid COBRA Up to 12 months of employer-paid COBRA
Equity vestingAcceleration of time-based awards scheduled to vest in the 6 months following termination Full acceleration of all time-based awards
Trigger windowTermination without cause / resignation for good reason outside CoC window Termination without cause / resignation for good reason during 3 months prior to, as of, or within 12 months post-CoC (double-trigger)

Other terms and governance context:

  • Base salary increased to $515,000 effective Jan 1, 2025; target bonus remains 45% of base .
  • Role evolution: Served as principal financial officer from Aug 2024; company appointed a new principal financial officer and principal accounting officer effective June 17, 2025, and later a CFO effective Oct 1, 2025, narrowing Kaplan’s finance-designated responsibilities going forward .
  • Compensation committee engages Aon Radford as independent consultant; committee oversees clawback policy and uses market/comparables and corporate goal achievement in setting pay .

Performance & Track Record

  • Operating, finance, and capital markets experience: executive roles at Chroma (President/CFO/CDO) and Prevail (CFO), with Prevail noted as acquired by Eli Lilly; prior Evercore MD and Cowen equity research analyst roles .
  • No TSR/revenue/EBITDA performance attribution to Kaplan’s tenure was disclosed in the proxy; annual bonus determinations are based on the board’s assessment of corporate goal achievement without published metric weightings .

Governance and Section 16 Compliance Notes

  • The company states Section 16(a) compliance for 2024 by directors/executive officers and >10% holders, except for two untimely reports by other executives; no delinquency noted for Kaplan in that disclosure .

Investment Implications

  • Pay mix and alignment: Kaplan’s 2024 compensation was heavily equity-based (option grant fair value $2.27M; RSUs $0.46M) alongside a pro-rated cash bonus ($79k), indicating high at-risk, service-based equity alignment but with no formal stock ownership guideline; beneficial ownership was zero as of March 31, 2025, with alignment primarily via unvested awards .
  • Retention and overhang: Key retention milestone is the one-year cliff on Aug 26, 2025, when 25% of his new-hire option and RSU awards vest, followed by monthly option vesting; this pattern can create periodic liquidity windows and potential insider selling pressure as shares vest, subject to trading windows and plans .
  • Change-in-control economics: Double-trigger structure (12 months salary + target bonus + unpaid prior-year bonus; 12 months COBRA; full acceleration of time-based equity) provides protection yet ties value realization to both transaction and qualifying termination; outside a CoC, severance is 9 months with partial (6 months) time-based acceleration, which supports retention while limiting windfalls .
  • Risk controls: Anti-hedging policy and adoption of a clawback under Rule 10D-1 strengthen governance; absence of explicit pledging prohibition and no executive ownership guideline may be viewed as weaker alignment practices by some investors .
  • Organizational transition: Appointment of a new PFO (June 2025) and CFO (Oct 2025) suggests maturation of the finance function; Kaplan’s role centers on operations/secretarial/treasury going forward, reducing finance key-person risk concentration but potentially lowering his influence over financial policy levers .

Appendices

Executive Snapshot (from Proxy)

  • Name/age/role as of April 25, 2025: Brett Kaplan, M.D., 51, Chief Operating Officer, Treasurer and Secretary; principal financial officer since August 2024 (superseded by later appointments) .
  • Education: M.B.B.Ch. and M.B.A., University of Witwatersrand .
  • 2024 compensation (selected): Salary $176,282; Option awards $2,272,734; RSUs $461,125; Bonus $79,327 .
  • 2024 grants and vesting: Option 465,000 @ $5.95 (25% cliff at 1 year, then monthly); 77,500 RSUs (25% annually for 4 years) .
  • Beneficial ownership: — shares (<1%) as of March 31, 2025; company had 67,575,767 shares outstanding .