Bettina M. Cockroft
About Bettina M. Cockroft
Independent director since May 3, 2023; age 58 as of October 10, 2025. She is Chief Medical Officer at Cilcare Inc. (since January 2025) and previously served as SVP & Chief Medical Officer at Sangamo Therapeutics (September 2019–May 2023). She holds an M.B.A. from MIT Sloan and an M.D. from the University of Genova; she also serves on Annexon, Inc.’s board, including the audit and science & technology committees. Core credentials: >20 years of biopharma clinical development leadership across multiple therapeutic areas and board-level governance experience including audit oversight .
Past Roles
| Organization | Role | Tenure | Committees/Impact |
|---|---|---|---|
| Sangamo Therapeutics, Inc. | Senior Vice President & Chief Medical Officer | Sep 2019–May 2023 | Led clinical development activities and operations |
| Cytokinetics, Inc. | Vice President, Clinical Research, Neurology | Aug 2017–Sep 2019 | Led clinical development of fast skeletal muscle troponin activators in ALS/SMA |
| Auris Medical AG | Chief Medical Officer | Sep 2013–Sep 2016 | Built and led clinical team responsible for two Phase 3 programs |
| Pharmaceutical executive consultant | Consultant | Oct 2016–Jul 2017 | Executive consulting across biopharma |
| Merck Serono S.A.; Novartis Consumer Health; Menarini Ricerche | Roles of increasing responsibility | Earlier career (dates not specified) | Clinical/biopharma roles across geographies |
External Roles
| Organization | Role | Tenure | Committees |
|---|---|---|---|
| Annexon, Inc. (public) | Director | Since Jan 2022 | Audit Committee; Science & Technology Committee |
| Cilcare Inc. (private) | Chief Medical Officer | Since Jan 2025 | Executive role (CMO) |
Board Governance
- Committee assignments:
- Nominating & Corporate Governance Committee: Chair; independent under Nasdaq rules .
- Compensation Committee: Member; independent under Nasdaq rules .
- Board and committee activity (2024):
- Board held 23 meetings; committees held 19 meetings (Audit 12, Compensation 4, Pricing 1, Nominating & Governance 2). Each incumbent director attended at least 75% of the meetings of the Board and committees of which they were a member .
- Independence:
- Board determined all directors except the CEO (Climaco) are independent per Nasdaq rules; independent directors meet at least four times annually in executive session without management .
- Director elections and terms:
- Nominated for re-election at the Nov 17, 2025 annual meeting; one-year terms to the 2026 annual meeting if elected .
- Related-party oversight and transactions:
- Audit Committee pre-approves related party transactions >$120,000; considers materiality, commercial reasonableness, and conflicts . No related person transactions reported for 2023 and 2024 .
Fixed Compensation
| Component | 2024 Policy Rate | Notes |
|---|---|---|
| Annual Board retainer (independent directors) | $40,000 | Effective April 1, 2024 |
| Chair – Audit Committee | $15,000 | Policy rate |
| Chair – Compensation Committee | $12,000 | Policy rate |
| Chair – Nominating & Governance Committee | $8,000 | Policy rate |
| Member – Audit Committee | $7,500 | Policy rate |
| Member – Compensation Committee | $6,000 | Policy rate |
| Member – Nominating & Governance Committee | $4,000 | Policy rate |
| Chair of the Board | $30,000 | Policy rate |
| In-person Board meeting fee | $2,500 per meeting | No fee for telephonic/video meetings |
| Director | Year | Fees Earned (Cash) | Option Awards ($) | Total |
|---|---|---|---|---|
| Bettina M. Cockroft | 2024 | $52,875 | – | $52,875 |
Notes: Dr. Cockroft’s committee roles (N&G Chair; Compensation member) align with policy rates (Chair $8,000; Member $6,000) plus retainer and any eligible in-person meeting fees, explaining the higher cash total vs base retainer .
Performance Compensation
| Grant Date | Instrument | Units | Strike Price | Term | Vesting | Status |
|---|---|---|---|---|---|---|
| Jun 6, 2025 | Stock Options | 1,517 | $12.12 | 10 years | Not disclosed (plan requires FMV strike; max 10-year term) | Subject to stockholder approval under 2020 Plan amendments |
| As of Dec 31, 2024 | RSUs outstanding | 1 | N/A | N/A | Not disclosed for directors | Outstanding aggregate count |
| As of Dec 31, 2024 | Options outstanding | 1 | Not disclosed (legacy grants) | Not disclosed | Not disclosed | Outstanding aggregate count |
Plan constraints and protections:
- Non-employee director annual total compensation cap of $300,000 (cash + equity at grant-date fair value) .
- No evergreen; no option/SAR repricing without stockholder approval; no tax gross-ups; options/SARs must be at least FMV and ≤10-year term; dividends on RSUs payable only upon vesting .
Other Directorships & Interlocks
| Entity | Relationship to CNSP | Potential Interlock/Exposure |
|---|---|---|
| Annexon, Inc. (public) | Unrelated; director role | No CNSP-disclosed dealings; serves on Annexon audit and science & technology committees |
| Cilcare Inc. (private) | Unrelated; CMO role | Therapeutic focus on hearing disorders; no CNSP-related transactions disclosed |
Expertise & Qualifications
- Education: M.B.A. (MIT Sloan); M.D. (University of Genova) .
- Domain expertise: Clinical development leadership across neurology and genetic medicine (ALS, SMA; Phase 3 programs), multinational program oversight .
- Board qualifications: Service on public-company audit and science/technology committees (Annexon), aligning with governance and R&D oversight needs .
Equity Ownership
| Item | Value | As-of |
|---|---|---|
| Shares beneficially owned | 4 (consists of options to purchase 4 shares exercisable within 60 days) | Oct 10, 2025 |
| % of shares outstanding | * (Less than 1%) | Based on 574,580 shares outstanding as of Oct 10, 2025 |
| Outstanding director RSUs (aggregate) | 1 | Dec 31, 2024 |
| Outstanding director options (aggregate) | 1 | Dec 31, 2024 |
Policies impacting alignment:
- Anti-hedging: Hedging transactions prohibited without prior approval .
- Insider trading compliance: 2024 late Form 4 filings were noted for several others; Dr. Cockroft was not listed among late filers .
- Pledging: No director-specific pledging disclosure; not indicated for Dr. Cockroft in proxy; beneficial ownership excludes pledged shares if any; none disclosed .
Governance Assessment
- Board effectiveness and engagement:
- Active committee leadership (N&G Chair) and compensation oversight responsibilities; independence affirmed under Nasdaq rules; directors meet in executive session ≥4x/year which supports robust oversight .
- 2024 workload was high (23 board meetings; 19 committee meetings), with ≥75% attendance by each incumbent director—supports engagement expectations for CNSP’s stage .
- Alignment and incentives:
- Cash-heavy director pay structure with clear, modest committee premiums and per-meeting fees; equity grants in 2025 (options) are at-market with 10-year term and subject to shareholder approval, consistent with shareholder-friendly plan terms (no repricing; no gross-ups; director comp cap) .
- Ownership remains de minimis (4 shares; <1%), which is typical for micro-cap companies with significant reverse split histories but still represents limited “skin-in-the-game” for alignment; no pledging disclosed; anti-hedging policy in place .
- Conflicts and related-party:
- No related-person transactions reported in 2023–2024; Audit Committee pre-approval and conflict screens are formalized; external roles (Annexon, Cilcare) do not indicate disclosed interlocks with CNSP .
- Signals to investor confidence:
- Positive: Independent leadership roles; structured director fee policy; executive sessions; plan protections (no repricing; cap) .
- Watch items: Very low personal ownership; proposed 2025 increase in authorized shares and 2020 Plan share pool (dilution risk) alongside new director option grants—monitor equity usage and refresh pace post-approval .
RED FLAGS (monitor)
- Low ownership alignment (beneficial ownership <1%)—consider whether the Board has or will adopt director stock ownership guidelines; none disclosed in proxy .
- Potential dilution from proposals to increase authorized shares and expand the 2020 Plan (requires shareholder approval)—track subsequent 8-K vote results and equity grant practices .
Note: All facts are drawn from CNS Pharmaceuticals’ 2025 DEF 14A proxy; where details were not disclosed, items are omitted per instruction.