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John Crowley

Chief Financial Officer at Centessa Pharmaceuticals
Executive

About John Crowley

John Crowley, age 51, has served as Centessa’s Chief Financial Officer since June 2024 and is the company’s principal financial officer; in May 2025 a new Chief Accounting Officer assumed principal accounting officer duties while Crowley remained CFO . He is a CPA with 20+ years of life sciences finance/operations experience, including CFO roles at Fusion Pharmaceuticals (through its June 2024 acquisition by AstraZeneca) and Merus, and senior finance leadership at Charles River, Ironwood, Vertex, and Sunovion; he graduated summa cum laude from Babson College with BS degrees in Economics and Accountancy . Compensation for 2024 reflected a pro-rated salary and bonus (135% of target on a pro-rata basis) and a material new-hire option grant aligned to TSR via strike-price-at-grant; the proxy does not disclose CFO-specific TSR/revenue/EBITDA metrics beyond company-wide bonus goals .

Past Roles

OrganizationRoleYears (as disclosed)Strategic impact
Fusion PharmaceuticalsChief Financial OfficerUntil June 2024 (through AZ acquisition)Led finance through M&A exit to AstraZeneca
Merus, Inc.EVP & Chief Financial OfficerNot disclosedPublic biotech CFO experience
Charles River LaboratoriesCorporate SVP, Corporate Controller & Chief Accounting OfficerNot disclosedEnterprise financial reporting/controls leadership
Ironwood, Vertex, SunovionSenior corporate finance rolesNot disclosedSupported launches, financings, BD in growth companies

External Roles

No public company directorships or external board roles are disclosed for Crowley in the latest proxy .

Fixed Compensation

MetricFY 2024Notes
Base salary (annual rate)$525,000 Per employment agreement (effective June 5, 2024)
Salary actually paid (pro‑rated)$295,313 Reflects June 10, 2024 start
Target annual bonus %40% of base salary Per employment agreement and NEO targets
Actual cash bonus paid$153,125 Committee set FY24 NEO bonuses at 135% of target; Crowley pro‑rated
Perquisites/All other comp$0 Company notes limited perquisites overall

Performance Compensation

Annual Incentive Plan (AIP) – FY 2024

ElementDetails
Plan designSenior Executive Cash Incentive Bonus Plan; objectives set by Compensation Committee
Performance metricsNon‑clinical/clinical advancement, team/infrastructure/governance, financial budget goals (company-wide)
WeightingsNot disclosed
Target40% of base salary (pro‑rated for 2024 given June start)
Outcome135% of target (pro‑rated for Crowley); bonus paid $153,125
ClawbackSubject to SEC/Nasdaq‑compliant clawback policy (malus/clawback windows described)

Equity Awards (granted 2024)

Award typeGrant dateQuantityStrike/PriceVestingExpiration
Stock options07/01/2024600,000$8.8025% on 07/01/2025; remaining 75% in 36 equal monthly installments thereafter (1/48th monthly) subject to service07/01/2034
EvidenceSEC Form 4 filed 07/02/2024 and proxy Outstanding Equity table

Vesting schedule and potential selling pressure:

  • Key cliff vest: 150,000 options on 07/01/2025; thereafter ~12,500 options vest monthly from 08/01/2025 for 36 months, creating a steady cadence of newly vesting shares that may create periodic liquidity windows, subject to trading windows/10b5‑1 plans .

Equity Ownership & Alignment

As of date / sourceBeneficial shares owned% of outstandingOptions exercisableOptions unexercisableNotes
12/31/2024 (proxy)600,000All 600,000 options unexercisable at YE 2024
04/24/2025 (beneficial ownership table)—%N/AN/ACrowley shows no beneficially owned shares as of record date

Ownership guidelines and policies:

  • Executive Director ownership guideline: 200% of base salary within five years; policy stated for Executive Directors (board members). Crowley (CFO; not a director) is not explicitly covered by this guideline in the proxy .
  • Trading/hedging/pledging: Insider policy prohibits derivatives and pledging; reduces misalignment/forced selling risk .

Employment Terms

TermProvision
Start dateEmployment agreement dated June 5, 2024; employment commenced June 10, 2024
Base salary / bonus$525,000 base; 40% target bonus
Severance (outside 1‑yr post‑sale)If terminated without cause or resigns for good reason: 12 months’ salary continuation plus employer portion of COBRA premiums up to 12 months or earlier qualifying events
Change‑in‑control (within 1‑yr post‑sale)If terminated without cause or resigns for good reason: lump sum equal to 12 months base + 100% of target bonus; 100% acceleration of time‑based equity; employer COBRA premiums up to 12 months or earlier qualifying events (double trigger)
280G treatmentBest‑net cut (pay in full or cut to avoid excise tax, whichever yields higher net)
ClawbackCompany‑wide Dodd‑Frank compliant compensation recovery policy; malus/clawback windows apply to bonuses and equity
Principal accounting officerMay 27, 2025: new CAO appointed and designated principal accounting officer; Crowley remains CFO/principal financial officer

Performance & Track Record

  • Transaction execution: Served as CFO of Fusion Pharmaceuticals through its acquisition by AstraZeneca in June 2024, evidencing deal execution experience directly prior to joining Centessa .
  • Internal controls/reporting: Centessa appointed a dedicated CAO in May 2025, separating PAO duties from the CFO role—positive for depth of controllership .

Compensation Committee, Peer/Process, and Say‑on‑Pay

  • Committee and advisor: Compensation Committee (independent) retained Aon Radford for market benchmarking in 2024 .
  • 2025 AGM remuneration votes: Shareholders approved the UK directors’ remuneration report (116,941,438 for; 395,738 against; 7,620,097 withheld) and remuneration policy (116,981,580 for; 376,720 against; 7,598,973 withheld) .

Risk Indicators & Red Flags

  • Hedging/pledging prohibited by policy; no pledging disclosed for Crowley .
  • No tax gross‑ups disclosed for Crowley; 280G best‑net cut applies .
  • Clawback policy in place (SEC/Nasdaq compliant) .
  • Related‑party transactions: None disclosed involving Crowley .

Investment Implications

  • Pay‑for‑performance alignment: 2024 cash bonus paid at 135% of target (pro‑rated), reflecting company‑level execution; equity is 100% stock options at fair‑market strike, aligning potential upside to TSR with multi‑year vesting .
  • Retention risk: Significant unvested options (600,000) with a one‑year cliff (vested 150,000 on 07/01/2025) and then monthly vesting through 2028 support retention while creating periodic liquidity windows; severance and double‑trigger CIC terms are standard and not excessively rich, limiting perverse incentives .
  • Trading signals: No insider sales by Crowley are disclosed; vesting cadence began mid‑2025, so monitor Forms 4 for exercise/sale activity post‑cliff and during open windows/10b5‑1 plans to assess potential selling pressure .
  • Governance/controls: Appointment of a standalone CAO in 2025 reduces key‑person concentration in finance and is supportive for control environment as the company advances clinical programs .