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Fred Hassan

Director at Cocrystal PharmaCocrystal Pharma
Board

About Fred Hassan

Independent director at Cocrystal Pharma (COCP) since April 2023; veteran biopharma operator and investor with prior CEO roles at Schering‑Plough and Pharmacia. He joined Warburg Pincus in 2010 (currently a Director) and serves as Chairman of investment firm Caret Group. Education: B.S. in Chemical Engineering from Imperial College London and MBA from Harvard Business School. Core credentials include global P&L leadership, M&A, regulatory/government affairs, and board service at large-cap and emerging biopharma companies .

Past Roles

OrganizationRoleTenureCommittees/Impact
Schering‑PloughChairman & CEO2003–2009Led turnaround and integration initiatives
Pharmacia CorporationChairman & CEO2001–2003Oversaw post‑merger integration (Monsanto + Pharmacia & Upjohn)
Pharmacia & Upjohn, Inc.Chief Executive Officer1997–2001Global operating leadership
WyethEVP; Board member1995–1997Senior operating leadership
Sandoz Pharmaceuticals (U.S.)Head of U.S. PharmaEarlierU.S. commercial leadership
Warburg PincusDirector2010–presentHealthcare investing; director-level role at PE firm
Caret GroupChairmanCurrentInvestment firm leadership

External Roles

CompanyRoleTenure
EyePoint PharmaceuticalsDirectorSince Sep 2024
Precigen (PGEN)DirectorSince Jun 2016
BridgeBio Pharma (BBIO)DirectorSince Aug 2021
Prometheus Biosciences (RXDX)DirectorMay 2021–Jun 2023
Time Warner Inc.DirectorOct 2009–Jun 2018
Amgen (AMGN)DirectorJul 2015–May 2021

Board Governance

  • Independence: The Board determined all Cocrystal directors (including Hassan) are independent under Nasdaq Rule 5605(a)(2) and applicable SEC rules .
  • Committee assignments: No committee assignments are shown for Hassan in the 2025 proxy’s committee matrix (Audit, Compensation, Corporate Governance & Nominating all blank for him) .
  • Attendance and engagement: All directors then serving attended over 75% of applicable Board/Committee meetings in 2024. The Board held no formal meetings in 2024 and approved actions by unanimous written consent twice; Audit Committee met 4 times, Compensation Committee once, Corporate Governance & Nominating Committee did not meet .
  • 2025 shareholder vote support: Elected with 4,440,602 “For,” 52,576 “Abstentions,” and 2,136,203 broker non‑votes (June 25, 2025 Annual Meeting) .

Fixed Compensation (Non‑Employee Director – FY 2024)

ComponentFY 2024
Fees Earned or Paid in Cash ($)$36,300
Committee/Chair FeesIncluded in cash total (not itemized)
Meeting FeesIncluded in cash total (not itemized)
Total Cash ($)$36,300

Performance Compensation (Equity)

ComponentFY 2024Notes
Stock Awards (RSUs) – Grant Date Fair Value ($)$14,198Aggregate grant-date FV for 2024; RSUs used for non‑employee directors
Options Granted in 2024Not disclosed for directorsRSUs were the reported director equity grants in 2024
Unvested RSUs Outstanding (12/31/2024)8,067 unitsAs of 12/31/2024
Unexercised Options Outstanding (12/31/2024)7,333 optionsAs of 12/31/2024

Performance metrics: The proxy does not disclose performance metrics tied to director equity; director equity appears time-vested (RSUs). No director‑specific performance goals disclosed for 2024 equity .

Other Directorships & Interlocks

CategoryDetails
Current public boardsEyePoint (since 9/2024), Precigen (since 6/2016), BridgeBio (since 8/2021)
Recent public boardsPrometheus Biosciences (5/2021–6/2023), Amgen (7/2015–5/2021), Time Warner (10/2009–6/2018)
Investment affiliationsDirector at Warburg Pincus (joined 2010); Chairman, Caret Group
Interlocks involving COCP ecosystemNone disclosed involving Hassan; Company notes related‑party oversight policies (see Related Party section)

Expertise & Qualifications

  • Extensive leadership across Big Pharma and biotech, including CEO roles (Schering‑Plough, Pharmacia/Pharmacia & Upjohn) and senior roles at Wyeth and Sandoz; deep experience in strategy, M&A, regulatory, finance and investments .
  • Education: B.S. Chemical Engineering (Imperial College London); MBA (Harvard Business School) .
  • Current healthcare investing oversight via Warburg Pincus and leadership at Caret Group .

Equity Ownership

ItemAmount
Total beneficial ownership1,023,845 shares (9.98% of outstanding)
Vested options included in beneficial ownership4,583 options (vested)
Vested RSUs included in beneficial ownership4,033 shares underlying vested RSUs
Unvested RSUs (12/31/2024)8,067 units (not part of “beneficial” unless vesting within 60 days)
Unexercised options (12/31/2024)7,333 options (unexercised)
Shares pledgedNot disclosed
Ownership guidelinesNot disclosed for directors

Insider Trades and Capital Commitment

DateTransactionSecurities/TermsConsideration
Apr 4, 2023Direct equity purchase via Securities Purchase Agreement; Hassan was one of two accredited investors and became a director several weeks later1,015,229 common shares at $1.97 per share (two equal $2,000,000 investments in total; Hassan purchased $2,000,000)$2,000,000 (Hassan’s investment); complied with Nasdaq Rule 5635
Oct 30, 2025Participated as an investor in a private placement alongside two directors and the Co‑CEO/CFOCompany sold 743,024 shares at $1.39 per unit in total; unregistered warrants for up to 1,486,048 shares at $1.24; warrants exercisable immediately; expire in 27 months. Individual investor allocation not disclosed$1.03M gross proceeds total to COCP from shares; potential ~$1.83M from warrants if fully exercised

Signal: Hassan’s repeated participation in company financings indicates alignment and confidence; transactions disclosed as compliant with listing rules/related‑party policies .

Related Party Transactions and Conflict Controls

  • 2023 equity financing: Hassan invested $2,000,000 at $1.97/share and was appointed a director several weeks later; the purchase price complied with Nasdaq Rule 5635 .
  • 2025 private placement: Hassan was one of four investors (three directors plus a co‑CEO/CFO) in an at‑the‑market private placement with immediate-exercisable warrants; individual allocations not disclosed .
  • Company policy: Bylaws require CFO procedures and majority Board approval for related‑party deals; fairness review, recusal of interested directors, and Corporate Governance & Nominating Committee oversight to monitor/enforce the policy .
  • Other related‑party items: Lease with an entity controlled by Director Phillip Frost (not Hassan) disclosed; reviewed under policy .

Governance Assessment

  • Positives

    • Independent director with deep operating and strategic credentials; brings large‑cap pharma governance experience and healthcare investing perspective .
    • Strong ownership and direct capital at risk: ~10% beneficial ownership and $2.0M primary purchase in 2023; further participation in 2025 financing supports alignment and confidence .
    • Robust shareholder support at 2025 election (4.44M “For” vs. 52.6k abstentions) .
  • Watchpoints

    • No committee assignments per 2025 proxy; committee work is a key lever for board effectiveness—continued absence could limit direct oversight influence .
    • Board process: 2024 had no formal Board meetings (actions by unanimous consent), and only limited committee meetings (Audit 4; Compensation 1; CG&N 0). While directors met >75% of applicable meetings, the low meeting cadence may raise engagement questions for a clinical‑stage biotech approaching milestones .
    • Related‑party optics: Insider participation in financings can create perception risks; however, disclosures note Nasdaq compliance and the Company’s related‑party review/recusal policy .
  • Red Flags

    • None disclosed specific to Hassan (no legal proceedings or pledging reported). Note: separate SEC matter pertains to another director (Dr. Phillip Frost), not to Hassan .

Director Compensation (Detail – FY 2024)

MetricFY 2024
Annual Retainer (cash)Included within Fees Earned; not itemized
Committee Membership/Chair FeesIncluded within Fees Earned; not itemized
Meeting FeesIncluded within Fees Earned; not itemized
Fees Earned or Paid in Cash ($)$36,300
Equity Compensation (RSUs) – Grant Date Fair Value ($)$14,198
Total Compensation ($)$50,498
Unvested RSUs at 12/31/2024 (#)8,067
Unexercised Options at 12/31/2024 (#)7,333

Notes: Director RSU awards are reported at grant‑date fair value under ASC 718; actual vesting terms for individual director grants not detailed in the proxy. The proxy lists vested components included in beneficial ownership (4,583 options; 4,033 RSUs) .

Additional Board Context

  • Committee composition (2025 proxy): Audit (Chair: Steven Rubin; members Rubin, Phillip Frost, Anthony Japour), Compensation (Chair: Steven Rubin; member Anthony Japour), Corporate Governance & Nominating (Chair: Richard C. Pfenniger; members Steven Rubin, Anthony Japour). Hassan not shown on committees .
  • Audit oversight and fees: Audit Committee recommended inclusion of audited 2024 financials in 10‑K; principal accountant fees for 2024: $126,000 (audit); $0 (audit‑related) .

Summary Signals for Investors

  • Board effectiveness: Hassan’s strategic experience is a plus; lack of committee roles and limited 2024 meeting cadence are watchpoints. Independence affirmed by the Board .
  • Alignment: High personal ownership and repeat insider participation in capital raises indicate meaningful alignment; disclosures emphasize policy compliance .
  • Shareholder support: Strong re‑election support in 2025 .