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Preethi Sundaram

Chief Strategy Officer at CATALYST PHARMACEUTICALSCATALYST PHARMACEUTICALS
Executive

About Preethi Sundaram

Catalyst Pharmaceuticals’ Chief Strategy Officer (CSO) since January 1, 2022; previously Chief Product Development Officer from July 2021. Age 49. Background spans >20 years in global medical operations and program leadership across Sanofi, Abbott, Covance, Neurovision & Medical Services, West Norwich Hospital (UK), and Sankara Nethralaya (India). Education: BA (Psychology, Univ. of Madras), BS (Optometry, Elite School of Optometry & BITS), PhD (Optometry, Anglia Ruskin Univ., UK), Executive Business Masters (London Business School) . Company performance context during tenure: 2024 net product revenue $489.3M and net income $163.9M; cumulative TSR value of $100 investment measured at $557 (company method) for 2022–2024 cohort .

Past Roles

OrganizationRoleYearsStrategic impact
SanofiGlobal Clinical Research Director, International Development2005–2010Led clinical/medical programs across geographies
SanofiGlobal Project Head, Multiple Therapeutic Area Programs2010–2017Drove cross-TA development portfolio execution
SanofiGlobal Head & VP, Medical Operations, Primary Care BU2017–2020Oversaw global medical operations and portfolio delivery
SanofiGlobal Head & VP, Medical Operations, General Medicines BUOct 2020–2021Accountable for portfolio financials and strategic milestones; led multiple portfolio management functions
Abbott LaboratoriesProject Lead, Immunoscience Development CenterPre-2005Program leadership in immunoscience
CovanceMedical Writer and Project Lead2003–2005Clinical/medical writing and project leadership
Neurovision & Medical ServicesClinical Director2001–2003Clinical leadership role
West Norwich Hospital (Cambridge, UK)Graduate Teaching Assistant and Clinical Supervisor1997–2001Academic/clinical supervision
Sankara Nethralaya Eye Hospital (Chennai, India)Clinical Faculty1995–1997Clinical faculty role

External Roles

OrganizationRoleYearsStrategic impact
Cilcare (private biotech in auditory sciences)Board of DirectorsDec 2024–PresentExternal board experience in auditory sciences

Fixed Compensation

MetricFY 2022FY 2023FY 2024
Base salary ($)415,674 440,000 485,000
Actual cash bonus ($)226,600 237,600 254,625
RSU grant fair value ($)750,800 290,995 355,006
Stock option grant fair value ($)733,187 1,164,003 1,420,124
All other compensation ($)12,200 13,200 13,800
  • 2024 bonus paid at 105% of target for all executive officers; implied target bonus for Dr. Sundaram ≈ $242,500 (≈50% of base) given actual $254,625 and 105% payout .

Performance Compensation

Annual Bonus Plan (2024)

MetricWeightTargetActual 2024Payout
Total revenues40%≥$475M≈$492M105% of target payout for executives
FIRDAPSE net product revenue— (part of total)≥$301.6M≈$306M105%
AGAMREE net product revenue— (part of total)≥$20M≈$46M105%
Acquisition (company or de-risked late-stage orphan asset)30%Acquisition by YE 2024Not achieved (evaluated >100 opportunities; 3 term sheets)105% overall payout despite shortfall
Global expansion (out-license AGAMREE or FIRDAPSE, APAC/LATAM)10%One agreementAGAMREE Canada out-license with KYE Pharmaceuticals (July 2024)105%
Operate to budget10%To plan≈$32M favorable net income vs budget105%
AGAMREE lifecycle plan adoption10%Board adoption by Aug 2024Approved Aug 2024105%

Notes: The Compensation Committee determined executive bonuses at 105% of targets after holistic review of results .

2024 Equity Awards – Detail

Award typeGrant dateQuantityStrike/PriceVestingExpirationGrant date fair value ($)
Stock options11/21/2024137,553 $21.12 1/3 each year over 3 years 11/21/2031 1,420,124
RSUs11/21/202416,809 1/3 each year over 3 years 355,006

Historical equity grant values for context shown in Fixed Compensation table above .

Equity Ownership & Alignment

ItemDetail
Total beneficial ownership (shares)355,569; less than 1% of outstanding
Options exercisable (included in beneficial ownership)310,564 (150,000 @ $5.49; 67,500 @ $7.07; 45,333 @ $18.59; 47,731 @ $14.15)
Unexercisable options (future vesting)75,000 @ $5.49 vest 7/6/2025; 22,667 @ $18.59 vest 12/27/2025; 95,462 @ $14.15 vest in two annual tranches beginning 12/8/2025; 137,553 @ $21.12 vest in three annual tranches beginning 11/21/2025
Unvested RSUs (future delivery)6,667 vest 12/27/2025; 13,710 vest in two annual tranches beginning 12/8/2025; 16,809 vest in three annual tranches beginning 11/21/2025
Hedging and pledgingProhibited for officers and directors (no hedging; no pledging/margin)
2024 insider option exercisesNone disclosed for Dr. Sundaram in 2024 option exercise table

Implications: Multiple 2025–2027 vesting events could create potential selling windows; however, policy prohibits hedging/pledging and no 2024 exercises were disclosed for Dr. Sundaram .

Employment Terms

ScenarioEconomics/Terms
Termination without cause or resignation for good reason1x base salary; accrued bonus; 12 months accelerated vesting of stock options; 12 months benefits continuation; non-compete during severance period
Change in control (CIC)All outstanding stock options and other equity awards automatically vest for designated executives (single-trigger equity acceleration)
Termination within 1 year post-CIC1x base salary; payment in full of target bonus for severance period; benefits continuation; subject to non-compete during severance period (double-trigger cash)
Designation under planDr. Sundaram is designated to receive benefits under the severance and CIC plan

Performance & Track Record

MetricFY 2022FY 2023FY 2024
Net product revenue ($000s)213,938 396,502 489,327
Net income ($000s)83,079 71,410 163,889
Cumulative TSR value of $100 (company method)496 448 557

Key 2024 operational achievements tied to incentives: exceeded revenue targets (total revenue ≈$492M; FIRDAPSE ≈$306M; AGAMREE ≈$46M), executed AGAMREE Canada out-license, operated ahead of budget, and secured Board approval of AGAMREE lifecycle plan; M&A target not completed despite extensive evaluation, resulting in 105% payout on annual bonus .

Compensation Committee Analysis and Peer Group

  • Independent Compensation Committee (3 members) overseeing executive pay and 2018 Stock Incentive Plan administration .
  • 2024 peer group (selected with Mercer) included: Acadia, Amicus, Amphastar, ANI, Collegium, Corcept, Dynavax, Halozyme, Harmony Biosciences, Insmed, Ionis, Ironwood, Pacira, PTC Therapeutics, Supernus, Ultragenyx; selected around projected 2024 product revenues and market practices .

Investment Implications

  • Pay-for-performance alignment: 2024 bonus tied to clear operating KPIs (revenue mix, out-licensing, budget discipline) with modest 105% payout; long-term equity mostly time-based options/RSUs with multi-year vesting—more retention than pure performance equity .
  • Retention risk: Single-trigger equity acceleration on CIC plus 1x salary and target bonus on double-trigger termination may reduce stickiness in a sale but multi-year vesting cadence (notably Nov/Dec 2025 onwards) supports near-term retention; non-compete applies during severance .
  • Insider selling pressure: No 2024 exercises disclosed for Dr. Sundaram; significant upcoming vesting in late 2025–2027 could add supply depending on personal liquidity needs and windows; hedging/pledging prohibited .
  • Ownership alignment: <1% ownership with substantial vested options creates leverage to upside; no pledging allowed; company-wide equity plan expanded in 2025 to sustain talent incentives (adds 5M shares) .
  • Execution track record: Company materially exceeded 2024 revenue targets and advanced partnering strategy; M&A pipeline active but disciplined; financial outcomes (higher net income, strong TSR per company method) support incentive payouts .