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Jane Pritchett Henderson

Director at CARGO Therapeutics
Board

About Jane Pritchett Henderson

Independent Class III director at CARGO Therapeutics since June 2024; age 59. Currently CFO of Apogee Therapeutics (Nasdaq) since January 2023; prior senior finance roles across Invivyd (Adagio), Turnstone Biologics, Voyager Therapeutics, and Kolltan Pharmaceuticals following ~20 years in healthcare investment banking. Education: B.S. in psychology from Duke University. At CARGO, she serves on the Audit Committee and Compensation Committee and is deemed independent under Nasdaq rules .

Past Roles

OrganizationRoleTenureCommittees/Impact
Apogee Therapeutics, Inc. (Nasdaq)Chief Financial OfficerJan 2023–presentCFO role overseeing finance
Invivyd, Inc. (f/k/a Adagio Therapeutics, Nasdaq)CFO & Chief Business OfficerDec 2020–Nov 2022Finance/business leadership for antibody therapeutics
Turnstone Biologics Corp. (private)Chief Financial OfficerJun 2018–Dec 2020CFO role
Voyager Therapeutics, Inc. (Nasdaq)CFO & SVP Corporate DevelopmentJan 2017–Jun 2018Finance and BD leadership
Kolltan Pharmaceuticals, Inc. (private; acquired by Celldex)SVP, Chief Financial & Business OfficerFeb 2013–Nov 2016Finance/business leadership until acquisition
Healthcare Investment BankingVarious roles~20 years prior to 2013Capital markets/transactions background

External Roles

OrganizationRoleTenureNotes
Akero Therapeutics, Inc. (Nasdaq)DirectorApr 2019–presentPublic company board
Ventus Therapeutics, Inc. (private)DirectorNov 2021–presentPrivate biopharma board
IVERIC Bio, Inc. (Nasdaq; acquired by Astellas)DirectorJan 2018–Jul 2023Service concluded at acquisition
Sesen Bio, Inc. (Nasdaq)DirectorOct 2013–Nov 2021Former public company director
Southern Methodist University, Dedman CollegeExecutive BoardOngoingAcademic board service

Board Governance

  • Board classification and tenure: Class III director; term expires at the 2026 annual meeting .
  • Committee assignments: Audit Committee (member) and Compensation Committee (member); Audit chaired by David C. Lubner; Compensation chaired by John Orwin .
  • Independence: Board determined Henderson independent under Nasdaq rules; Audit and Compensation Committees comprised entirely of independent directors .
  • Attendance: In 2024 the Board met 9 times; Audit 4; Compensation 6; Nominating 2; R&D 4. In 2025, each Board member attended at least 75% of applicable meetings .
  • Leadership: John Orwin is Chairperson; independent directors hold regular executive sessions .
  • 2025 annual meeting voting outcomes (context): Class II directors received strong support; auditor ratification passed decisively .

Fixed Compensation

ComponentAmountNotes
Annual cash retainer (non-employee director)$40,000/yearPaid quarterly in arrears
Audit Committee member retainer$7,500/yearNon-chair member rate
Compensation Committee member retainer$5,000/yearNon-chair member rate
2024 fees earned (Henderson)$30,144Partial-year service from June 2024

Performance Compensation

Equity TypeShares/UnitsGrant Date Fair Value ($)VestingCadence/Change-in-Control
Director Initial Option GrantUp to 50,000 (capped at ≤$800k fair value)N/A (program term)1/36 monthly over 3 yearsGranted upon board entry; vests fully on change-in-control (single-trigger)
Director Annual Option GrantUp to 25,000 (capped at ≤$400k fair value)N/A (program term)Vests in full by next annual meeting or 1-year anniversaryAnnual cadence; vests fully on change-in-control (single-trigger)
Henderson – 2024 Option Awards59,187 shares underlying options$835,392Per program (mix of initial/annual grants as applicable)Subject to single-trigger full vesting on change-in-control
  • Performance metrics tied to director compensation: None disclosed (director equity awards are service-based options) .
  • Clawback policy: Adopted Nov 9, 2023 for executive incentive-based comp; not specific to directors’ equity retainers .

Other Directorships & Interlocks

EntityRelationship to CRGXPotential Interlock/Conflict
Apogee Therapeutics (CFO)No CRGX-related party transactions disclosedNo transactions involving Henderson disclosed; independence affirmed
Akero, Ventus, prior IVERIC, Sesen boardsExternal board rolesNo CRGX-related party transactions involving Henderson disclosed
  • Related party transactions (CRGX): Disclosures center on investor financings; no transactions identified involving Henderson .

Expertise & Qualifications

  • Finance and capital markets leadership as CFO and senior BD executive across multiple biotech companies; oncology and biopharma industry experience .
  • Independent director; Audit and Compensation Committee member (Audit financial expert designation is held by Lubner, not Henderson) .
  • Governance and board experience across public and private companies; academic board role .

Equity Ownership

HolderCommon Shares OwnedOptions Exercisable ≤60 DaysTotal Beneficial% Outstanding
Jane Pritchett Henderson32,91932,919<1%
  • Hedging/pledging: Company Insider Trading Policy prohibits hedging and pledging of Company securities, supporting alignment with shareholders .

Governance Assessment

  • Strengths:

    • Independent director with deep CFO/finance experience; active on Audit and Compensation Committees .
    • Independence explicitly affirmed; committee independence complied .
    • Attendance meets at least 75% threshold; Board/committee engagement evidenced by 2024 meeting cadence .
    • Hedging/pledging prohibited; director equity paid in options (at-risk, performance-levered via stock price) .
  • Watch items / potential red flags:

    • Single-trigger full vesting of director equity awards upon change-in-control; while common, it can reduce retention incentives through a transaction .
    • Significant external time commitments (CFO role at Apogee + multiple boards); monitor sustained attendance and committee workload, though 2025 attendance threshold met .
    • No director ownership guidelines disclosed; beneficial ownership is modest (<1%), though option-based structure provides leverage to performance .
  • Shareholder signals:

    • 2025 annual meeting showed strong support for director slate (Class II) and auditor ratification, indicating broader investor confidence in governance framework; Henderson not up for election in 2025 (Class III) .
  • Say-on-Pay context:

    • As an emerging growth company, CRGX does not conduct non-binding say-on-pay votes, reducing one governance feedback channel for investors .