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Marc Rubin

Director at CURISCURIS
Board

About Marc Rubin

Marc Rubin, M.D., age 70, is an independent director of Curis, Inc. (CRIS) and has served on the board since June 2010; he is currently Chair of the Compensation Committee and a member of the Audit Committee . Dr. Rubin holds an M.D. from Cornell University Medical College and completed board-certified subspecialty training in medical oncology and infectious diseases at the National Cancer Institute; he also served on senior staff in the infectious diseases section at NCI before entering industry . His core credentials span clinical development leadership and executive roles across Bayer Schering Pharma/Schering AG, Berlex Pharmaceuticals, and GlaxoSmithKline, as well as executive chair and CEO experience at Titan Pharmaceuticals .

Past Roles

OrganizationRoleTenureCommittees/Impact
Titan Pharmaceuticals, Inc.Executive ChairmanMay 2009 – Aug 2022 Oversight of biopharma strategy; previously President & CEO (Oct 2007 – Dec 2008)
Bayer Schering Pharma AGHead of Global R&D; Member of Board of ManagementJun 2006 – Feb 2007 Member, Executive Committee of Bayer HealthCare LLC; led global R&D
Schering AG / Berlex Pharmaceuticals, Inc.Executive Board Member; Chairman of Schering Berlin Inc.; President of Berlex PharmaceuticalsOct 2003 – Jun 2006 Led North American operations; clinical/commercial development leadership
GlaxoSmithKline plcSVP Global Clinical Pharmacology & Discovery Medicine; various clinical/commercial development roles2001 – 2003 (SVP); 1990 – 2003 (various) Global clinical development leadership
National Cancer Institute (NIH)Subspecialty training; Investigator/Senior Staff (Infectious Diseases)1983 – 1986 (training); 1986 – 1989 (Investigator/Senior Staff) Clinical research; oncology and infectious disease expertise

External Roles

OrganizationRoleTenureCommittees/Impact
Galectin Therapeutics Inc. (public)DirectorCurrent Not disclosed in CRIS proxy
Rogosin Institute (non-profit)DirectorPrior Not disclosed
Soricimed Biopharma, Inc. (private)DirectorPrior Not disclosed
Titan Pharmaceuticals, Inc. (public)Executive Chairman; prior DirectorPrior (Exec Chair until 2022) Governance/executive leadership

Board Governance

  • Independence: The board determined in March 2025 that Dr. Rubin is independent under Nasdaq listing standards; all members of Audit, Compensation, and Nominating committees are independent (with Audit members also meeting Rule 10A-3 and Compensation members meeting Rule 10C-1 criteria) .
  • Committee assignments: Audit Committee member; Compensation Committee Chair. Audit members: Greenacre (Chair), Kaitin, Rubin; Compensation members: Rubin (Chair), Hohneker, Kaitin .
  • Meeting cadence and attendance: Board met 11 times in FY2024; each director attended at least 75% of aggregate board and relevant committee meetings, and all current directors attended the 2024 annual meeting .
  • Board leadership: Chairman of the Board is independent (Martyn D. Greenacre) with explicit responsibilities including executive session leadership, agenda setting, and stockholder communications .
  • Risk oversight: Audit oversees financial controls, data privacy and cybersecurity; Compensation oversees compensation policies and management succession; Nominating/Governance oversees board composition and ESG policies .

Fixed Compensation

ComponentAmountNotes
Fees Earned or Paid in Cash (2024)$70,000 Consistent with policy: $45,000 director retainer; plus $10,000 Audit member; $7,500 Compensation member; $7,500 Compensation Chair
Annual Director Retainer (policy)$45,000 Approved Jan 2024 and Jan 2025
Committee Member Retainers (policy)Audit: $10,000; Compensation: $7,500; Nominating: $5,000 Applies to members
Committee Chair Retainers (policy)Audit Chair: $10,000; Compensation Chair: $7,500; Nominating Chair: $5,000 Additional to committee member retainer

Performance Compensation

Equity AwardGrant DateSharesExercise PriceVestingTerm
Non-employee Director OptionJan 20244,250 Fair market value (last trading day before grant) 100% on Jan 28, 2025 (cont. service) 10 years
Non-employee Director OptionJan 202516,000 (incl. 14,400 contingent) Fair market value (date of grant) 100% on Jan 28, 2026; 14,400 contingent on stockholder approval of Plan Amendment No. 1 within 12 months 10 years
2024 Director Option Fair Value (reported)FY2024$39,221 Accounting fair value (ASC 718)

No director performance-vesting metrics (e.g., TSR, EBITDA) are disclosed for non-employee director equity awards; awards are time-based options per policy .

Other Directorships & Interlocks

CompanyRelationship to CRISPotential Interlock/Conflict
Galectin Therapeutics Inc.Unrelated biotech; Dr. Rubin is a director No CRIS-related transactions disclosed; no related-party exposure indicated in CRIS proxy

Expertise & Qualifications

  • Clinical development and executive leadership across major pharma/biotech (Bayer Schering, Schering/Berlex, GSK) with board and executive committee roles; deep medical, commercial, and scientific expertise .
  • Medical credentials: M.D. (Cornell), oncology and infectious diseases subspecialty training and Senior Staff at NCI .
  • Current public board service: Galectin Therapeutics Inc. .

Equity Ownership

HolderShares HeldShares Acquirable Within 60 DaysTotal Beneficial Ownership% Outstanding
Marc Rubin, M.D.1,441 34,100 35,541 <1%
  • Aggregate options held (12/31/2024): 34,350 options outstanding (non-employee director) .
  • Pledging/Hedging: Company policy prohibits short sales, derivatives, and pledging except by exception; none of CRIS directors/NEOs have pledged shares per footnote (1) .
  • Stock ownership guidelines: Not implemented for directors/executives (minority practice among peer group per 2018 review) .

Governance Assessment

  • Strengths: Independent status; committee leadership (Compensation Chair) and Audit membership; documented attendance at ≥75% meetings; active executive sessions under independent Chair; robust related-party transaction review via Audit Committee; prohibition of hedging/short sales .
  • Alignment and incentives: Director pay mixes cash retainers with time-based equity options; 2024 cash $70,000 and equity fair value $39,221 for Dr. Rubin, supporting long-term alignment but without performance-vesting features .
  • Shareholder signals: 2024 say-on-pay passed with ~89.26% support, signaling investor acceptance of overall compensation approach .
  • Watch items / potential red flags:
    • No director stock ownership guidelines may reduce formal “skin-in-the-game” requirements versus peers .
    • Increased reliance on equity, including contingent director options in 2025 pending share pool expansion (Amendment No. 1), highlights dilution sensitivity; board seeking +1,255,000 shares to the plan (approx. 15% of shares outstanding as of Mar 24, 2025), and contingent awards will be forfeited if not approved .
    • No performance-based equity metrics for directors; awards are time-based .
  • Conflicts/related-party exposure: No related-party transactions disclosed involving Dr. Rubin; recent financings involved institutional holders, not directors .

Compensation Committee Analysis (structure and process)

  • Composition and independence: Rubin (Chair), Hohneker, Kaitin; all independent under Nasdaq standards including Rule 10C-1 considerations .
  • Use of independent consultant: Willis Towers Watson periodically retained; Compensation Committee determined no conflicts of interest with its retention; peer group reviewed in 2022–2023 for 2023–2024 executive benchmarking .
  • Clawback/Recovery: Compensation Committee oversees implementation and administration of compensation recovery policy .
  • Committee activity: Compensation Committee met five times in FY2024 .

Director Compensation (structure detail)

ElementPolicy
Annual cash retainer$45,000 per non-employee director
Board Chair additional retainer$35,000
Committee member retainersAudit: $10,000; Compensation: $7,500; Nominating/Governance: $5,000
Committee chair retainersAudit Chair: $10,000; Compensation Chair: $7,500; Nominating Chair: $5,000
Annual equity (2024)Option for 4,250 shares; vests 100% on first anniversary; 10-year term; fair market value grant price
Annual equity (2025)Option for 16,000 shares including 14,400 contingent on Plan Amendment No. 1; vests 100% on first anniversary; 10-year term; fair market value grant price

Say-on-Pay & Shareholder Feedback

  • Frequency: Annual say-on-pay adopted by stockholders in 2024; next frequency vote due in 2029 .
  • 2024 say-on-pay approval: ~89.26% “FOR” .
  • Committee response: Considered results in 2025 executive compensation decisions; continues pay-for-performance philosophy .

Related Party Transactions (policy and recent activity)

  • Policy: Audit Committee reviews/approves related-person transactions >$120,000 (executives, directors, nominees, 5% holders and immediate family); may approve only if not inconsistent with CRIS’s best interests .
  • Recent financings: July 2023, October 2024, March 2025 offerings involved institutional investors (Maverick, M28 Capital, Bleichroeder, entities affiliated with Thomas A. Satterfield Jr.); no director participation disclosed .

Risk Indicators

  • Hedging/pledging prohibition and insider trading policy; no pledges by directors/NEOs per footnote (1) .
  • Cybersecurity oversight by Audit Committee with periodic management reporting and processes described .
  • D&O indemnification for directors and standard indemnification agreements in place; D&O insurance maintained if available .

Equity Compensation Plan Dilution Context

MetricValue
Securities to be issued upon exercise of outstanding awards (Dec 31, 2024)1,160,251 (weighted avg exercise price $33.44)
Shares remaining available under equity plans (Dec 31, 2024)1,307,061
Proposed increase (Amendment No. 1 to Fifth Amended and Restated 2010 Plan)+1,255,000 shares
Dilution context (if approved; as of 3/24/2025 OS 8,487,818)~15% of outstanding shares

Board rationale: higher-than-projected equity needs in 2025 due to stock price and RSU fungible share counting; contingent awards granted pending stockholder approval .

Attendance & Engagement

BodyFY2024 MeetingsNotes
Board of Directors11 All directors attended ≥75% of aggregate board/committee meetings; all current directors attended 2024 annual meeting
Audit Committee5 Greenacre (Chair), Kaitin, Rubin
Compensation Committee5 Rubin (Chair), Hohneker, Kaitin
Nominating & Corporate Governance Committee4 Kaitin (Chair), Borgman, Greenacre

Summary Implications for Investors

  • Governance quality appears solid: independent director leading Compensation Committee, strong attendance, and clear committee oversight frameworks .
  • Alignment is primarily time-based equity plus cash retainers; absence of ownership guidelines reduces formal alignment requirements; pending share pool increase underscores dilution sensitivity and equity reliance .
  • No disclosed conflicts or related-party transactions involving Dr. Rubin; say-on-pay support (89.26%) suggests broad investor acceptance of compensation practices .