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Matthew Fust

Director at Crinetics Pharmaceuticals
Board

About Matthew K. Fust

Independent director of Crinetics Pharmaceuticals (CRNX) since February 2018; age 60. Former public-company CFO (Onyx, Jazz, Perlegen, ALZA) and designated “audit committee financial expert” by the board. Education: B.A., University of Minnesota; M.B.A., Stanford Graduate School of Business. Independent status confirmed; board led by independent chair Wendell Wierenga, Ph.D.

Past Roles

OrganizationRoleTenureCommittees/Impact
Onyx Pharmaceuticals, Inc.Executive VP & CFO2009–2013 (through sale to Amgen)Led finance through sale; public biopharma CFO credentials
Jazz Pharmaceuticals, Inc.CFO2003–2008Specialty pharma finance leadership
Perlegen SciencesCFO2002–2003Genetics company finance lead
ALZA CorporationSVP & CFO1996–2002Pharmaceutical finance; senior leadership

External Roles

CompanyPublic/PrivateRoleCommittees
Atara Biotherapeutics, Inc.PublicDirectorAudit Committee member
Ultragenyx Pharmaceutical, Inc.PublicDirectorAudit; Nominating & Corporate Governance member
Neumora Therapeutics, Inc.PublicDirectorAudit; Compensation member
MacroGenics, Inc.Public (prior)Former Director
Dermira, Inc.Public (acquired)Former Director
Sunesis Pharmaceuticals, Inc.Public (prior)Former Director

Potential network interlock: CRNX director Camille Bedrosian, M.D., previously served as Executive VP & CMO at Ultragenyx (2018–2023), while Fust currently serves on Ultragenyx’s board; no related-party transactions disclosed with Ultragenyx.

Board Governance

  • Committees: Audit Committee chair; Compensation Committee member. Audit met 4 times in 2024; Compensation met 4 times in 2024. Board met 4 times in 2024; all directors attended at least 75% of board/committee meetings.
  • Independence: Board determined all directors except CEO are independent under Nasdaq/SEC rules; Fust independent.
  • Leadership: Independent board chair (Wendell Wierenga, Ph.D.); CEO and chair roles separated.
  • Related-party oversight: Audit Committee reviews and approves related person transactions; formal written policy adopted.

Fixed Compensation

ComponentAmountNotes
Annual Cash Retainer$41,000Effective June 7, 2024 (amended program)
Audit Committee Chair Fee$20,000Annual, in addition to retainer
Compensation Committee Member Fee$7,500Annual, member (not chair)
2024 Fees Earned (Cash)$67,875Actual cash paid in 2024

Performance Compensation

Equity ComponentGrant Value (2024)Units Outstanding (12/31/2024)Vesting / TermsPerformance Metrics
RSUs$152,0143,400 RSUsAnnual director RSUs vest on the earlier of first anniversary or next annual meeting, subject to service None (time-based)
Stock Options$341,75042,092 optionsOptions have 10-year term; annual director option grants vest per program schedule; exercise price set at grant-date FMV None (time-based)

Director program for continuing directors: annual options valued $350,000 and RSUs valued $150,000; initial director grants at options $525,000 and RSUs $225,000, with 3-year vesting.

Other Directorships & Interlocks

LinkDescriptionGovernance Signal
Ultragenyx tieFust on Ultragenyx board; CRNX director Bedrosian previously EVP/CMO at UltragenyxNetwork linkage; not a disclosed related-party transaction
Compensation Committee interlocksCRNX compensation committee members (incl. Fust) have never been CRNX officers; no reciprocal comp committee interlocks with CRNX executivesLow conflict risk per proxy disclosure

Expertise & Qualifications

  • Designated “audit committee financial expert”; financially sophisticated under Nasdaq.
  • Deep public-company CFO experience across biopharma; broad board service across therapeutics.
  • Education: B.A. (Minnesota) and M.B.A. (Stanford GSB).

Equity Ownership

MetricAmount
Total beneficial ownership (shares)67,428 (includes exercisable options within 60 days)
Common shares held directly21,936
Options exercisable within 60 days45,492
RSUs outstanding (12/31/2024)3,400
Ownership % of outstanding shares<1%
Pledging/HedgingProhibited by policy (pledging, short sales, derivatives)
Stock ownership guidelinesNon-employee directors must hold 3x annual cash retainer; 5-year compliance window; retain 50% of net shares until compliant (adopted Feb 20, 2025)

Governance Assessment

  • Strengths:

    • Independent director; audit chair and audit committee financial expert; strong board oversight structure with independent chair.
    • Documented attendance (≥75% of meetings); active committee engagement.
    • Clear director compensation policy with market benchmarking and caps via plan limits; transparent equity vesting mechanics.
    • Robust insider trading policy (no hedging/pledging) and formal related-party transaction review process.
    • Strong investor support for executive pay (Say-on-Pay approval ~97.3% in 2024), signaling broader governance confidence.
  • Potential Risks / RED FLAGS to monitor:

    • Multi-board commitments (Atara, Ultragenyx, Neumora) may pose time-allocation risk during critical CRNX milestones (e.g., paltusotine PDUFA). No attendance shortfall disclosed, but monitor ongoing engagement.
    • Network interlock with Ultragenyx via fellow CRNX director’s prior executive role; no related-party transactions disclosed, but watch for future collaborations or transactions for independence optics.
    • Director equity is time-based (no performance hurdles), which is standard for directors but offers limited explicit pay-for-performance linkage; alignment relies on stock price and ownership guidelines.
  • Additional signals:

    • Deferred Compensation Plan enables directors to defer fees and time-based RSUs, aligning long-term incentives; company may make discretionary contributions.
    • Indemnification agreements and D&O insurance in place; standard for public boards.

Insider Trades and Compliance

  • Section 16 compliance: To the company’s knowledge, directors and officers complied with filing requirements in 2024; one late Form 3 was filed by the Chief Commercial Officer (not involving Fust).
  • No director-specific Form 4 activity disclosed in the proxy; ongoing prohibition on hedging/pledging reduces alignment risk.