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Rogério Vivaldi Coelho

Director at Crinetics Pharmaceuticals
Board

About Rogério Vivaldi Coelho

Rogério Vivaldi Coelho, M.D., age 61, has served as an independent director of Crinetics since January 2022. A physician with an MBA, he has 20+ years of rare disease and biopharma leadership spanning Genzyme, Spark Therapeutics, Bioverativ, and Sigilon Therapeutics, with deep commercialization and global market access experience. He completed an endocrinology residency in Brazil and a genetics fellowship at Mount Sinai focused on Gaucher disease, and later became the first physician in Brazil to use enzyme replacement therapy for Gaucher patients .

Past Roles

OrganizationRoleTenureCommittees/Impact
Sigilon Therapeutics, Inc.President, CEO and DirectorRetired Dec 2023Led company; board-level oversight
Bioverativ Inc.EVP & Chief Global Therapeutics Officer2016–2018Built commercial org; led sales/marketing; until acquisition by Sanofi
Spark Therapeutics, Inc.Chief Commercial Officer2014–2016Launched global commercial ops; advocacy, market access, medical affairs for Luxturna
GenzymeMultiple senior roles: President (Rare Disease; Renal & Endocrine), SVP & GM Latin America~20 years through 2010sLed >15 orphan product approvals in >20 countries
Academic/TrainingMD (Universidade do Rio de Janeiro), Endocrinology Residency (UERJ), Genetics Fellowship (Mount Sinai)First in Brazil to treat Gaucher with enzyme replacement therapy

External Roles

OrganizationRoleTenureNotes
Sigilon Therapeutics, Inc.DirectorRetired Dec 2023Former public company board role

No other current public company directorships are disclosed for Dr. Vivaldi in Crinetics’ proxy .

Board Governance

  • Board class: Class I director; nominee for a term expiring at 2028 annual meeting .
  • Independence: Board determined he is independent under SEC/Nasdaq; audit committee confirms independence and financial literacy .
  • Attendance: In 2024, each director attended at least 75% of board and applicable committee meetings; board met 4 times .
  • Committees (2024):
    • Audit Committee: Member; 4 meetings; chair is Matthew K. Fust .
    • Research & Development Committee: Member; 4 meetings; chair is Dr. Bedrosian .
    • Global Therapeutics Strategy & Access Committee: Chair; established Sep 2024; met once in 2024 .

Fixed Compensation

Director compensation program (effective June 7, 2024):

ComponentAmount ($)Notes
Annual cash retainer (non‑employee directors)41,000Program adopted after Aon review
Chair of Board (additional)30,000
Committee chair retainersAudit $20,000; Compensation $15,000; Nominating & Governance $10,000; R&D $15,000
Committee member (non‑chair) retainersAudit $10,000; Compensation $7,500; Nominating & Governance $5,000; R&D $7,500
Initial equity (upon appointment)Options $525,000; RSUs $225,000Vests over 3 years, in equal annual installments
Annual equity (for continuing directors)Options $350,000; RSUs $150,000Vests at first anniversary or next annual meeting
Annual limit on director compensation$750,000 (normal); $1,000,000 (initial year)Per 2018 Plan; exceptions allowed in extraordinary circumstances

2024 actual compensation (non‑employee director):

NameFees Earned or Paid in Cash ($)Stock Awards ($)Option Awards ($)Total ($)
Rogério Vivaldi Coelho, M.D.58,000 152,014 341,750 551,764

Performance Compensation

Annual director equity design and vesting:

Grant TypeAnnual Value ($)VestingNotes
Options (Annual)350,000Vests on earlier of 1-year anniversary or next annual meetingTime‑based; performance metrics not specified for director grants
RSUs (Annual)150,000Same as aboveTime‑based
Options (Initial)525,0003 equal annual installments over 3 yearsTime‑based
RSUs (Initial)225,0003 equal annual installments over 3 yearsTime‑based

Outstanding equity (as of Dec 31, 2024):

SecurityCount
RSUs outstanding3,400
Options outstanding73,750

Performance metrics tied to director compensation:

Metric TypeDisclosure
Quantitative performance conditionsNone disclosed; director equity is time‑based vesting

Other Directorships & Interlocks

  • Compensation committee interlocks: None. No member of Crinetics’ compensation committee served as a Crinetics officer; no CRNX executive served on boards or compensation committees of entities with executives on CRNX’s compensation committee .

Expertise & Qualifications

  • Medical and scientific: MD; endocrinology residency; genetics fellowship (Gaucher focus); first physician in Brazil to use enzyme replacement therapy for Gaucher .
  • Commercial leadership: Built commercialization/orgs at Spark and Bioverativ; led >15 orphan approvals at Genzyme across >20 countries .
  • Financial literacy: Audit committee states all members meet SEC/Nasdaq financial literacy requirements .
  • MBA: COPPEAD, Universidade Federal do Rio de Janeiro .

Equity Ownership

Beneficial ownership (as of April 14, 2025):

HolderShares Beneficially Owned% of Shares OutstandingFootnote Detail
Rogério Vivaldi Coelho, M.D.91,550 <1% Includes 14,400 common shares and 77,150 options exercisable within 60 days

Additional alignment policies:

  • Stock ownership guidelines (adopted Feb 20, 2025): Non‑employee directors must hold 3x annual cash retainer; 5 years to comply; must retain at least 50% of net shares from awards for one year after vesting until compliant; eligible securities include time‑vesting RSUs and common shares; performance RSUs count once targets are met .
  • Hedging/pledging: Prohibited for directors, officers, employees (includes margining, short‑selling, puts/calls) .

Governance Assessment

  • Independence and engagement: Independent director with audit committee financial literacy; participates across Audit, R&D, and chairs Global Therapeutics Strategy & Access—indicating substantive oversight of commercialization strategy; attended ≥75% of meetings in 2024 (board met 4x; audit 4x; R&D 4x; new commercialization committee met once) .
  • Alignment: Director pay mixes cash retainer plus meaningful equity; standardized program with market benchmarking and capped annual plan limits; equity is time‑based (no discretionary performance metrics for directors), complemented by new ownership guidelines and anti‑hedging/pledging policy to strengthen alignment .
  • Ownership: Beneficial ownership of 91,550 shares (<1%); options exercisable within 60 days total 77,150, RSUs outstanding 3,400; no pledging permitted, reducing collateralization risk .
  • Conflicts/related parties: Audit committee reviews related party transactions; proxy discloses Radionetics arrangement involving CEO; no related‑party transactions involving Dr. Vivaldi are disclosed—low conflict exposure for this director .
  • Shareholder sentiment: 2024 say‑on‑pay passed with ~97.3% approval, reflecting strong investor support for broader compensation governance (an indirect positive signal for board oversight quality) .