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Derek J. Maetzold

Derek J. Maetzold

President and Chief Executive Officer at CASTLE BIOSCIENCES
CEO
Executive
Board

About Derek J. Maetzold

Founder, President & CEO of Castle Biosciences since inception (September 2007); age 63; B.S. in Biology from George Mason University. Castle delivered 2024 revenue of $332.1M (+51% YoY) and 96,071 test reports (+36% YoY), exceeding guidance; pay-versus-performance shows 2024 company TSR at 77.54 (vs 62.79 in 2023) and net income of $18.2M, alongside revenue of $332.1M . He is a co‑inventor on technologies at Castle and Encysive and has co-authored multiple publications .

Past Roles

OrganizationRoleYearsStrategic Impact
Encysive PharmaceuticalsLeadership rolesNot disclosedBiopharma commercialization experience
Schering‑Plough (now Merck)Leadership rolesNot disclosedLarge-cap pharma commercial execution
Integrated CommunicationsLeadership rolesNot disclosedLife sciences communications
Amylin PharmaceuticalsLeadership rolesNot disclosedEndocrinology commercialization
Sandoz (Novartis)Leadership rolesNot disclosedGlobal pharma operating experience

External Roles

OrganizationRoleYearsNotes
PreludeDxDirectorNot disclosedIndustry board service
Coalition for 21st Century MedicineDirectorNot disclosedAdvocacy/industry policy
IMPACT MelanomaDirectorNot disclosedPatient advocacy

Fixed Compensation

Metric (USD)FY 2022FY 2023FY 2024
Base Salary$660,000 $686,400 $715,572
Target Bonus % of SalaryNot disclosed95% target pre‑2024 100% target (increased from 95%)
Actual Annual Bonus Paid$771,375 $893,350 $921,657
All Other Compensation$18,300 (401k match, etc.) $26,234 $20,250 (incl. $19,800 401k match; $100 wellness; $350 gift)

Notes: 2024 CEO base was $715,572; target bonus increased to 100% of base; actual payout 128.8% of target reflecting corporate performance .

Performance Compensation

  • 2024 short‑term incentive outcomes (CEO bonus solely corporate; no individual modifier):
    • Corporate goals: revenue and long‑term initiatives (validation study, e‑ordering metrics, SCC reimbursement). Corporate achievement certified at 128.8% of target; CEO payout 128.8% of target .
2024 STI DesignWeightTargetActualPayout Factor
Revenue75% $305.0M $332.1M 108.8% weight contribution
Long‑term initiatives (validation, e‑ordering, SCC reimbursement)25% Specified thresholds Achieved (10% + 5% + 5%) 20.0% weight contribution
Total Corporate Factor100%128.8%
  • Long‑term incentives (LTI) structure and metrics:
    • 2024: CEO LTI mix 50% PSUs / 50% time‑based RSUs; PSUs on 3‑year performance period with metrics: revenue, successful launch of a new commercial test, and achieving positive EBITDA by end of 2026; RSUs vest over 4 annual installments .
    • No executive options granted since 2021 (shift to RSUs/PSUs) .
    • 2022 PSU tranche: cumulative revenue goal achieved; 50% vested Aug 2024; remaining 50% scheduled to vest Aug 8, 2025 (time‑based) .
2024 LTI Grants (3/4/2024)Shares/UnitsGrant‑Date Fair Value
Time‑based RSUs124,437 $2,641,798
PSUs (3‑yr; revenue, test launch, positive EBITDA)124,437 target $2,641,798

Equity Ownership & Alignment

ItemDetail
Beneficial Ownership900,885 shares; 3.1% of outstanding (based on 28,839,188 shares as of Mar 21, 2025)
Components (illustrative)Includes 78,335 held directly; multiple family/trust holdings; and 530,322 options exercisable within 60 days
Outstanding CEO Equity at 12/31/2024Unvested RSUs include 124,437 (3/4/2024), 66,991 (12/9/2022), 66,991 (12/23/2022), 15,424 (12/10/2021); Unvested PSUs include 124,437 (3/4/2024)
Option InventoryMultiple tranches; example: 170,000 @ $29.50 (12/13/2019); 87,100 @ $59.16 (12/10/2020); 79,782/26,594 @ $40.52 (12/10/2021, w/ 26,594 unexercisable)
2024 Vest/Exercises121,274 shares vested (RSUs/PSUs) with $3,448,649 value; 10,686 options exercised, $198,653 value realized
Ownership GuidelinesCEO guideline 3x base salary; all directors and executive officers meet guidelines as of Mar 21, 2025
Hedging/PledgingProhibited for directors and officers (no hedging, short sales, margin, or pledging)

Vesting calendar insight (potential selling pressure): remaining 50% of the 2022 PSU awards are scheduled to vest on Aug 8, 2025 (time‑based) following certification in Aug 2024, a notable date for incremental free‑trading supply if shares are not otherwise retained .

Employment Terms

  • Employment Agreement: Original June 2008; amended/restated Sept 2012; amended Feb 2017 and June 2019; 2024 base $715,572 and target bonus 100% .
  • Severance and Change‑in‑Control (Severance Plan):
    • Non‑CIC covered termination: 18 months base salary; 150% of higher of most recent target or actual annual bonus (paid over 18 months); up to 18 months COBRA; 18 months acceleration of time‑vesting equity; pro‑rata PSUs based on service with final PSU shares per actual performance .
    • CIC double‑trigger (3 mo. before to 12 mo. after CIC): lump sum 36 months base salary; 300% of target bonus; up to 3 years COBRA; full vesting of time‑based equity and PSUs at 100% of target; if awards not assumed at CIC and he remains to closing, all unvested awards vest (PSUs at target or based on actual, if greater) .
    • Voluntary resignation without good reason: 12 months continued base salary .
  • Retirement Policy: Eligible executives (including Mr. Maetzold) may receive accelerated vesting of time‑based equity scheduled within 24 months post‑retirement (and certain performance awards if already earned), supporting orderly transitions and succession planning .
  • Clawback: SEC/Nasdaq‑compliant; mandatory recovery of incentive comp upon financial restatement (3‑year lookback) .
  • Perquisites/Tax: Limited perqs; no post‑employment tax gross‑ups; no single‑trigger equity acceleration on CIC .

Board Governance (and dual‑role implications)

  • Position on Board: Director since 2007; not independent; no committee memberships .
  • Structure: Independent, non‑employee Chair (Daniel M. Bradbury); separation of Chair/CEO intended to enhance independent oversight .
  • Board Independence and Activity: 7 of 8 directors independent; board met 8 times in 2024; all directors attended ≥75% of meetings .
  • Director Pay for CEO: Employee directors receive no additional director compensation (Mr. Maetzold: none) .

Dual‑role assessment: While he is CEO and director, the presence of an independent Chair and fully independent key committees (Audit/Comp/Nominating) tempers concentration of power and supports governance balance .

Director Compensation (for context; CEO receives none)

  • Non‑employee director policy: Annual cash retainer $47,500; annual equity grant ~$200,000 in RSUs; new director initial RSU ~$350,000; committee retainers and chair premiums detailed; awards vest on standard schedules .
  • 2024 Say‑on‑Pay: 97% support (improved after prior years’ low support), following investor outreach to holders representing ~60% of outstanding shares .

Compensation Structure Analysis

  • Mix and trend: Significant shift from options to RSUs/PSUs since 2021; 2024 CEO LTI 50% performance‑based; overall 51% of CEO 2024 reported pay “at‑risk” (cash incentives + PSUs) .
  • Metric evolution: To reduce overlap with annual plan, 2024 PSUs added two 3‑year metrics—new commercial test launch and achieving positive EBITDA by end of 2026—alongside multi‑year revenue; PSU performance horizon moved from 2 to 3 years .
  • Grant timing change: Annual equity shifted to Q1 of following year (no grants in 2023; resumption in Q1 2024) to align with results and goal‑setting; explains YoY “spike” in 2024 stock award values .
  • Governance practices: Double‑trigger CIC acceleration; clawback; stock ownership guidelines; prohibition on hedging/pledging; no guaranteed bonuses or excessive perqs; independent compensation consultant (Aon) with no identified conflicts .

Compensation Peer Group (benchmarking)

  • Peer group construction considers life sciences diagnostics/tools/biotech, revenue 0.75x–5x projected, market cap 0.5x–4x; 2024 peer group includes 17 companies (e.g., ADPT, ADMA, GH, NTRA, NEO, VCYT, TWST) .
  • Positioning: Committee uses benchmarking without a fixed percentile target; at selection time, Castle was ~13th percentile for market cap, ~28th percentile for revenue, ~79th percentile for growth vs peers .

Say‑on‑Pay & Shareholder Feedback

  • 2024 SoP approval ~97%; outreach led by Comp Committee Chair with CEO participation; feedback informed metric separation in LTI, adoption of clawback and ownership guidelines, and expanded disclosures .

Related‑Party Transactions and Other Risk Indicators

  • Family employment: Son (John), daughter (Emily), son (Peter), and brother‑in‑law (Greg Holzapfel) employed in non‑officer roles; 2024 total comp $897,469, $346,423, $336,851, and $493,498 respectively; approved under related‑party policy .
  • AltheaDx acquisition (2022): Mr. Maetzold (then a director/security holder of AltheaDx) received $1,347,172 in initial consideration; milestone earn‑outs ultimately zero; this was disclosed and closed; no remaining obligations .
  • Policies: Prohibition on hedging/pledging; clawback; double‑trigger CIC; independent chair; 7/8 independent directors; all mitigate certain governance risks .

Performance & Track Record (company context)

  • 2024 highlights: Revenue $332.1M (+51% YoY), test reports 96,071 (+36% YoY), exceeded revenue guidance; cash and marketable securities of ~$293M at YE 2024 (proxy summary) .
  • Pay‑versus‑performance: PEO “compensation actually paid” and TSR presented; TSR improved in 2024 vs 2023, while revenue grew materially and net income was positive in 2024 .

Investment Implications

  • Alignment and retention: 3.1% beneficial ownership with prohibitions on hedging/pledging and a 3x salary ownership guideline (met) align incentives; robust double‑trigger CIC package and retirement policy reduce flight risk but increase potential CIC costs/dilution on acceleration .
  • Incentive quality: Increased use of 3‑year PSUs with revenue, pipeline launch, and positive EBITDA gating improves pay‑for‑performance calibration; grant‑timing change ties awards to actual results and budget setting .
  • Near‑term flow dynamics: Scheduled vesting of remaining 2022 PSUs on Aug 8, 2025 (time‑based) could add incremental supply depending on disposition, while annual RSU tranches continue to vest; monitor Form 4s around these dates for potential selling pressure .
  • Governance watch‑items: Multiple family members employed and the prior AltheaDx related‑party transaction merit continued monitoring, though mitigated by formal related‑party review processes, independent board/committees, and strong 2024 say‑on‑pay support .