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Mani Mohindru

Director at CytomX TherapeuticsCytomX Therapeutics
Board

About Mani Mohindru

Dr. Mani Mohindru is an independent Class I director of CytomX Therapeutics, Inc. (CTMX), serving since December 2020. She is 53 years old and holds a Ph.D. in neurosciences from Northwestern University, along with a Masters in biotechnology and a BS in human biology (Hons) from the All India Institute of Medical Sciences, New Delhi; her background spans CEO roles, CFO/CSO responsibilities at public biotechs, and prior work as a sell-side biotech equity research analyst at UBS, Credit Suisse, and ThinkEquity . She is nominated for re‑election at the 2025 Annual Meeting, with continued independence under Nasdaq rules including eligibility for Audit Committee service .

Past Roles

OrganizationRoleTenureCommittees/Impact
Novasenta (private)Chief Executive Officer and directorApr 2021–Mar 2024Led immunotherapy-focused drug discovery
CereXis, Inc. (biopharma)Chief Executive OfficerDec 2019–Oct 2020Focused on rare tumor indications
Cara Therapeutics, Inc. (public)Chief Financial Officer & Chief Strategy OfficerAug 2017–Dec 2019Finance and corporate strategy leadership
Curis, Inc. (public)VP Corporate Strategy & Investor Strategy; Chief Strategy OfficerJun 2013–Aug 2017Strategy, investor relations leadership
UBS, Credit Suisse, ThinkEquityEquity research analyst (biotech)Not disclosed (many years)Sector coverage expertise
Privately-held biotech (cofounder)Co-founderNot disclosedEntrepreneurship; consulting in healthcare

External Roles

OrganizationRoleSinceNotes
Cardiff Oncology (public)DirectorJun 2021Clinical-stage oncology; public company board
Roshon Therapeutics (private)DirectorOct 2024Privately-held biopharma
SAB Biotherapeutics (public)Director (prior)Not disclosedPreviously served; clinical-stage biopharma

Board Governance

  • Committee assignments: Audit Committee member; stepped down from Compensation Committee in March 2025 .
  • 2024 committee service: Audit Committee and Compensation Committee member .
  • Independence: Board determined she is independent under Nasdaq rules; meets heightened independence criteria applicable to Audit Committee (Rule 10A‑3) .
  • Attendance: In FY2024, each director attended at least 75% of Board and committee meetings; Board met 6 times; Audit 4; Compensation 5; Nominating 2. All directors attended the virtual 2024 Annual Meeting .
  • Audit Committee composition and oversight: Audit Committee comprised of Matthew P. Young (chair), Mani Mohindru, and Halley Gilbert; responsibilities include auditor oversight, financial reporting, internal controls, and related party transaction review .

Fixed Compensation

YearBoard Retainer ($)Committee Fees ($)Total Cash Fees ($)
202440,000 13,500 (Audit member $7,500; Compensation member $6,000) 53,500
202340,000 13,500 (Audit member $7,500; Compensation member $6,000) 53,500

Notes:

  • No meeting fees; cash paid quarterly in arrears .
  • Lead Independent Director retainer exists ($25,000) but applies to Matthew P. Young, not Dr. Mohindru .

Performance Compensation

YearInstrumentShares GrantedGrant DateGrant Date Fair Value ($)Vesting TermsExercise Price Policy
2024Stock Option38,000May 15, 202458,732 Vests in full on earlier of next annual meeting or first anniversary Equal to Nasdaq closing price on grant date
2023Stock Option25,000Jun 14, 202325,123 Vests in full on earlier of next annual meeting or first anniversary Equal to Nasdaq closing price on grant date

Additional terms:

  • New non‑employee director initial option grant updated in Mar 2024 to 76,000 shares, vesting 1/36 monthly over 3 years (for new directors; not applicable to Dr. Mohindru in 2024) .
  • Upon a change in control, vesting of all non‑employee director equity awards accelerates in full .

Other Directorships & Interlocks

CompanyRelationship to CTMXPotential Interlock/Conflict
Cardiff Oncology (public)External directorshipNone disclosed in CTMX proxy; remains independent at CTMX
Roshon Therapeutics (private)External directorshipNone disclosed in CTMX proxy
SAB Biotherapeutics (public)Prior external directorshipNone disclosed in CTMX proxy

CTMX policies:

  • Related party transactions are reviewed under a written policy by the Audit Committee; no director-specific related party transactions involving Dr. Mohindru disclosed since Jan 1, 2024 .

Expertise & Qualifications

  • Significant life sciences leadership (CEO, CFO/CSO) and corporate strategy background, plus sell-side biotech equity research experience .
  • Academic credentials: Ph.D. (Northwestern); Masters and BS (AIIMS, New Delhi) .
  • Current Audit Committee member with independence meeting heightened criteria; committee chair roles held by others (Audit chair: M. Young) .

Equity Ownership

HolderDirect SharesOptions Exercisable (within 60 days)Total Beneficial OwnershipOwnership % of Outstanding
Mani Mohindru, Ph.D.0 (not listed) 148,000 148,000 <1% (“*”) of 80,621,293 shares outstanding

Additional notes:

  • As of Dec 31, 2024, outstanding options to purchase CTMX shares held by Dr. Mohindru total 148,000 .
  • Non‑employee directors held options only; no RSUs/PSUs for directors as of Dec 31, 2024 .
  • CTMX prohibits hedging transactions in company equity securities by directors; insider trading policy governs trading conduct; pledging policy details not explicitly disclosed in the cited section .

Governance Assessment

  • Independence and Committee Engagement: Dr. Mohindru is independent under Nasdaq rules and meets heightened Audit Committee independence criteria; she actively serves on the Audit Committee and served on the Compensation Committee through March 2025, evidencing sustained governance engagement .
  • Attendance and Participation: Board and committees had regular meetings in 2024; each director attended at least 75% of meetings; all directors attended the 2024 Annual Meeting—consistent with baseline governance expectations .
  • Compensation Mix and Alignment: Director pay is balanced between fixed cash retainers and annual option grants; cash fees align with committee memberships; equity grants moved from 25,000 to 38,000 options year‑over‑year (program change), increasing equity at‑risk exposure .
  • Ownership Alignment: Her beneficial ownership comprises exercisable options with no direct common share holdings listed—an observation relevant to “skin‑in‑the‑game” analyses for some investors .
  • Conflicts and Red Flags: No related‑party transactions involving Dr. Mohindru are disclosed; CTMX prohibits hedging and maintains indemnification agreements for directors. No family relationships or governance red flags are indicated in the proxy .

RED FLAGS (none disclosed):

  • No pledging or related-party transactions involving Dr. Mohindru disclosed; attendance above minimum threshold; committee independence satisfied .

Signals to watch:

  • Equity-only beneficial ownership (options) without disclosed direct share holdings ;
  • Committee rotation (stepping down from Compensation Committee in March 2025) may reflect evolving governance load balancing across directors .