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Pasha Sarraf

Director at Cue BiopharmaCue Biopharma
Board

About Pasha Sarraf

Dr. Pasha Sarraf, age 55, was appointed as an independent director of Cue Biopharma in March 2025; he is a physician-scientist with MD/PhD from Harvard Medical School and training at MGH and NIH, with 50+ publications and multiple patents, and a background spanning operating leadership in biotech, venture creation, strategy consulting, and sell-side research . His tenure on CUE’s board began March 10, 2025; he entered into the company’s standard indemnification agreement upon appointment . The board determined in April 2025 that all directors other than the CEO are independent under Nasdaq rules, which includes Dr. Sarraf .

Past Roles

OrganizationRoleTenureCommittees/Impact
Upupa AdvisoryPrincipal2023–present Strategic advisory; biotech focus
Matterhorn BiosciencesCEO & Executive Board Member2021–2023 Built team; scaled TCR platform; drove value demonstration
Flagship PioneeringOperating Partner2020–2021 Led team discovering novel genetic circuits in Parkinson’s; initiated drug discovery later licensed by GSK
Leerink Partners (SVB Leerink)Senior Wall Street Analyst, Managing DirectorNot dated in proxy (prior to 2020) Biotech equity research leadership
McKinsey & CompanyLife Sciences Practice; PartnerJoined 2008; Partner 2015–2018 Strategy, diligence, forecasting; various roles 2008–2018

External Roles

OrganizationRoleTenure/StatusNotes
PolarityBioDirectorCurrent Biotechnology company; governance oversight
Praesidia BiotherapeuticsDirector & ChairmanCurrent Biotechnology company; board chair leadership

Board Governance

  • Board size and nominations: 7 members pre-meeting; six nominees (including Dr. Sarraf) for election for one-year terms at the June 4, 2025 annual meeting; board size reduced to six after Mr. Driscoll’s term ends .
  • Independence: Board determined in April 2025 that all directors except the CEO are independent under Nasdaq rules (audit/comp/nom-gov committees comprised of independent directors) .
  • Leadership: Independent Chairman is Dr. Frank Morich; board separates Chair and CEO roles; independent directors meet at least twice annually in executive session .
  • Attendance: In 2024, board met 35 times; all then-serving directors attended ≥75% of board and committee meetings; Dr. Sarraf was not yet on the board in 2024 .
  • Committee membership: As of the 2025 proxy, committees were constituted without Dr. Sarraf listed; board expected to identify another audit committee member and “financial expert” after the Annual Meeting (committee composition listed below) .
CommitteeMembers (as disclosed)ChairDr. Sarraf Member?
AuditFrederick Driscoll; Frank Morich; Patrick Verheyen Frederick Driscoll Not listed
CompensationPeter A. Kiener; Pamela Garzone; Patrick Verheyen Peter A. Kiener Not listed
Corporate Governance & NominatingFrank Morich; Peter A. Kiener; Frederick Driscoll Frank Morich Not listed
Science & Technology StrategyPeter A. Kiener; Frank Morich; Pamela Garzone Peter A. Kiener Not listed

Fixed Compensation

ComponentAmountNotes
Annual cash retainer (non-employee directors)$35,000 Paid in cash annually
Chairman of the Board (if non-employee)$30,000 Additional annual cash retainer
Audit Committee Chair$15,000 Annual cash fee
Audit Committee Member$7,500 Annual cash fee
Compensation Committee Chair$10,000 Annual cash fee
Compensation Committee Member$5,000 Annual cash fee
Corporate Governance & Nominating Chair$8,000 Annual cash fee
Corporate Governance & Nominating Member$4,000 Annual cash fee
Science & Technology Strategy Chair$10,000 Annual cash fee
Science & Technology Strategy Member$5,000 Annual cash fee

Performance Compensation

Award TypeGrantVestingKey Terms
Initial stock option (upon board appointment)48,800 shares 1/3 at 1-year anniversary; balance in 8 equal quarterly installments thereafter over total 3 years Granted March 2025 under Director Compensation Policy
Annual stock option (each year after Dec 31)24,400 shares 50% at 6 months; remaining 50% at 12 months from grant First trading day following Dec 31 each year
Non-employee director annual compensation cap (2025 Plan)$750,000 (incumbent); $1,000,000 (initial year) Applies to cash plus grant-date fair value; exceptions only in extraordinary circumstances (non-participating recipient)
ClawbackSubject to CUE Dodd-Frank Compensation Recovery Policy Participant agrees to forfeiture/reimbursement if required Applies to awards under 2025 Plan
Change in Control treatmentNo automatic vesting for employees; “double trigger” for employees; exception noted for non-employee directors Awards other than those to non-employee directors require termination without cause/for good reason within 2 years for full acceleration Non-employee director awards excluded from double trigger; plan highlights note exception
Performance Metrics Tied to Director CompensationDisclosure
Revenue/EBITDA/TSR/ESG metricsNot applicable; director awards are time-based options under the director policy

Other Directorships & Interlocks

CompanyRolePublic/Private Status in ProxyPotential Interlock/Conflict Notes
PolarityBioDirectorNot specified in proxy (biotechnology company) No related-party transactions with CUE disclosed
Praesidia BiotherapeuticsDirector & ChairmanNot specified in proxy (biotechnology company) No related-party transactions with CUE disclosed

Expertise & Qualifications

  • MD/PhD (Harvard Medical School), internal medicine and rheumatology training at MGH and NIH; >50 publications and patents on novel therapies and targets .
  • Operating leadership in biotech (Matterhorn CEO), venture creation (Flagship Operating Partner), strategy consulting (McKinsey Partner), and capital markets (Leerink Managing Director) .
  • Board leadership experience as chairman and director in biotech companies (PolarityBio; Praesidia Biotherapeutics) .

Equity Ownership

HolderShares OwnedShares Underlying Options Exercisable ≤60 DaysShares Underlying Warrants Exercisable ≤60 DaysTotal Beneficially Owned% of Class
Pasha Sarraf* (Less than 1%)

Note: The table includes only instruments exercisable within 60 days of April 11, 2025; Dr. Sarraf’s initial option grant is not counted under this standard due to vesting/exercisability timing .

Governance Assessment

  • Independence and appointment: Dr. Sarraf is independent under Nasdaq rules and was appointed March 10, 2025 via nom-gov committee recommendation; no arrangements or related-party transactions under Item 404(a) were disclosed at appointment, which supports investor confidence in independence .
  • Engagement and committees: High board activity historically (35 meetings in 2024), but committee assignments for Dr. Sarraf were not yet disclosed in the 2025 proxy; the board indicated it would add an audit committee member and “financial expert” post-meeting, implying ongoing committee refresh; investors should monitor post-Annual Meeting committee allocations .
  • Compensation alignment: Director cash retainer is modest; equity is time-based options with annual cadence; plan features include clawback and non-employee director compensation caps, aligning with governance best practices; however, the plan’s change-in-control provisions carve out non-employee directors from double-trigger protection (i.e., different vesting treatment), which investors should note when assessing alignment in a sale scenario .
  • Ownership: As of April 11, 2025, no beneficial ownership reported under SEC’s 60-day standard; as a new director with an unexercisable initial grant, low near-term reported ownership is typical but warrants tracking for alignment over time .
  • Policies and guardrails: Insider trading policy prohibits hedging/pledging without limited preapproval, which reduces alignment risk; robust governance guidelines and independent leadership structure further support board effectiveness .
  • Say-on-pay context: Board recommended FOR advisory vote on NEO compensation and FOR the 2025 Stock Incentive Plan; while not directly about director pay, continued shareholder support of compensation frameworks is a sentiment indicator to monitor .

RED FLAGS and Watch Items

  • Change-in-control vesting exception for non-employee directors may enable more favorable vesting outcomes versus employee “double trigger,” potentially diluting discipline in sale scenarios; monitor specific award agreements and any updates to director award terms .
  • Committee seat clarity: Dr. Sarraf’s committee assignments were not disclosed in the proxy; investors should watch for post-Annual Meeting committee changes, particularly audit committee financial expert designation amid board size changes .
  • Ownership build: Track Form 4 filings for subsequent equity grants or purchases to assess “skin in the game”; initial grant is time-based and not immediately exercisable .

Director Compensation Context (2024 snapshot for peers)

Non-Employee DirectorFees Earned (Cash)Option Awards (Grant-Date Fair Value)All Other CompensationTotal
Pamela Garzone$50,000 $45,750 $95,750
Patrick Verheyen$57,500 $45,750 $103,250
Frank Morich$70,137 $45,750 $115,887
Peter A. Kiener$64,000 $45,750 $110,000 $219,750
Frederick Driscoll$54,000 $45,750 $99,750
Pasha Sarraf— (appointed 2025)

Note: 2024 director comp table predates Dr. Sarraf’s appointment; his compensation will follow the director policy outlined above .

Equity Ownership

CategoryRecord DateShares OutstandingNotes
Common stock outstandingApril 11, 202561,819,101 One vote per share; used for ownership % computation

Related Policies and Disclosures

  • Indemnification: Standard form indemnification agreement executed by Dr. Sarraf upon appointment .
  • Insider Trading: Hedging and pledging prohibited (limited exceptions with preapproval); directors subject to policy filed as Exhibit 19.1 to FY2024 10-K .
  • Committee Charters and Governance Docs: Available on Investors & Media—Corporate Governance webpage .

Summary Implications for Investors

  • Strong domain expertise and independent status support board effectiveness; absence of related-party transactions at appointment reduces conflict risk .
  • Compensation structure uses modest cash with time-based options, clawbacks, and caps—generally shareholder-friendly; monitor change-in-control treatment for directors and future committee roles for Sarraf .
  • Initial reported ownership is minimal due to timing; track subsequent filings to evaluate ownership alignment over time .