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Michael F. Higgins

Director at Cyclerion Therapeutics
Board

About Michael F. Higgins

Independent director since 2023; age 62; Audit Committee Chair and Compensation Committee member. Background spans senior operating and finance roles in biopharma (Ironwood COO; Genzyme corporate finance/business development), venture/EIR experience, and multiple board chairmanships; designated by CYCN’s board as an “audit committee financial expert.” Education: B.S. Cornell University; MBA, Tuck School of Business at Dartmouth College .

Past Roles

OrganizationRoleTenureCommittees/Impact
Ironwood Pharmaceuticals, Inc.Senior Vice President, Chief Operating Officer2003–2014Helped launch and build numerous companies; operating leadership at a commercial-stage biotech
Genzyme CorporationVice President Corporate Finance; Vice President Business DevelopmentPre‑2003Senior business roles at a leading biopharma; transaction experience
Polaris PartnersEntrepreneur-in-Residence2015–2020Company-building; portfolio support

External Roles

OrganizationRoleTenure/StatusNotes
Voyager Therapeutics, Inc.Chairman; Interim President & CEOChair since Jun 2019; Interim CEO Jun 2021–Mar 2022Public company; CYCN director Steven E. Hyman also serves on Voyager’s board (interlock)
Pulmatrix, Inc.ChairmanSince Apr 2020Public company
Nocion Therapeutics, Inc.DirectorSince Sep 2020Private biopharma
Camp4 Therapeutics CorporationDirectorSince Oct 2017Private company
Sea Pharmaceuticals, LLCDirectorSince Oct 2016Private company
KinDex Pharmaceuticals, Inc.DirectorSince Mar 2016Private company
Genocea Biosciences Inc.Director (prior)Feb 2015–May 2022Public company; prior board service

Board Governance

  • Independence: Board affirmatively determined Higgins is independent under Nasdaq standards .
  • Committee leadership/memberships:
    • Audit Committee: Chair; financially literate; designated “audit committee financial expert” .
    • Compensation Committee: Independent member (committee chaired by Dr. De Souza) .
    • Nominating & Corporate Governance Committee: Not a member .
  • Attendance: Board met six times and acted by consent three times in 2024; no director attended <75% of Board/committee meetings; all directors attended the 2024 annual meeting .
  • Overboarding policy: CYCN guidelines limit directors to ≤4 public company boards (≤2 for sitting public-company CEOs); company regularly evaluates director commitments .

Fixed Compensation

YearFees Earned or Paid in Cash (USD)Notes
2024$12,000One-time cash fee to each outside director; no ongoing cash fees to conserve cash

Restricted Stock (Director Equity Retainer)

Grant DateShares GrantedVesting ScheduleVested (as of 4/21/2025)Unvested (as of 4/21/2025)
Nov 30, 202320,000Ratable monthly over 42 months through June 1, 2027, subject to continued board service9,172 10,828
  • No director meeting fees or committee chair/member cash fees disclosed beyond the one-time cash payment; equity retainer is principal form of director compensation .

Performance Compensation

Performance Metric Tied to Director CompensationDisclosure
None disclosed for non-employee directorsDirector pay is cash plus time-based restricted stock; no performance-based director metrics disclosed

Other Directorships & Interlocks

CounterpartyInterlock/OverlapPotential Relevance
Voyager Therapeutics, Inc.Higgins (Chair) and CYCN director Dr. Steven E. Hyman also a Voyager directorInformation flow network; monitor for any transactions requiring related-party review (none disclosed)
Multiple private biopharma boardsHiggins serves on several private boardsTime commitments monitored under CYCN overboarding policy

Expertise & Qualifications

  • Financial expertise: Board-designated audit committee financial expert; prior roles in corporate finance and business development (Genzyme) and COO (Ironwood) .
  • Company-building: Serial entrepreneur; EIR at Polaris Partners; multiple chair roles; extensive board governance experience .
  • Education: B.S. Cornell; MBA Tuck (Dartmouth) .

Equity Ownership

HolderShares Beneficially Owned% of OutstandingComposition
Michael F. Higgins30,740<1%10,740 shares held directly; 20,000 restricted shares (9,172 vested; 10,828 unvested)

Related Transactions / Recent Purchases

DateTransactionSharesPriceNotes
Mar 21–25, 2025Private Placement (PIPE) purchase9,090$2.75 per shareRegistration rights; customary terms; gross proceeds to CYCN $1.375M across all investors
  • Insider trading policy: Company prohibits hedging by directors and officers; compliance officer oversees pre-clearance/10b5‑1 plans .
  • No pledging of company stock disclosed for Higgins in the proxy’s ownership tables .

Governance Assessment

  • Strengths:

    • Independent director with deep finance/operating credentials; designated audit committee financial expert; chairs Audit Committee, improving financial oversight quality .
    • Strong attendance (≥75% threshold met; full director attendance at 2024 annual meeting) supports engagement .
    • Equity-heavy director pay aligns interests with shareholders; minimal cash fees to conserve cash .
    • Insider purchase via March 2025 PIPE indicates confidence/alignment; transaction reviewed under related-party framework and accompanied by standard registration rights .
  • Watch items / potential red flags:

    • Interlock with Voyager through another CYCN director (Dr. Hyman) requires vigilant related-party oversight if any future CYCN–Voyager dealings arise (none disclosed) .
    • Time commitments: Multiple board roles (two public chairs plus several private boards) warrant continued monitoring under CYCN’s overboarding policy, though policy limits are acknowledged and monitored by the board .
    • Compensation Committee currently does not retain an independent compensation consultant, which may limit external benchmarking, though the committee has authority to engage advisers if needed .

Overall: Higgins’ independence, audit leadership, and insider purchase bolster investor confidence; monitor interlocks and workload, and consider periodic external comp benchmarking for continued best-practice governance .