Cryoport - Q2 2023
August 9, 2023
Transcript
Operator (participant)
Good afternoon, ladies and gentlemen, welcome to the Cryoport second quarter 2023 earnings conference call. At this time, all lines are in a listen-only mode. Following the presentation, we will conduct a questioning answer session. If at any time during this call you require immediate assistance, please press star zero for the operator. As a reminder, this call is being recorded. I will now turn the call over to your host, Mr. Todd Fromer, from KCSA Strategic Communications. Please go ahead.
Todd Fromer (Principal and President)
Thank you, operator. Before we begin today, I would like to remind everyone that this conference call contains certain forward-looking statements. All statements that address our operating performance, events, or developments that we expect or anticipate occurring in the future are forward-looking statements. These forward-looking statements are based on management's beliefs and assumptions and not on information currently available to our management team. Our management team believes that these forward-looking statements are reasonable as and when made. However, you should not place undue reliance on any such forward-looking statements because such statements speak only as of the date when made. We do not undertake any obligation to publicly update or revise any forward-looking statements, whether as a result of new information or if future events or otherwise, except as required by law.
In addition, forward-looking statements are subject to certain risks and uncertainties that could cause actual results, events, and developments to differ materially from our historical experience and our present expectations or projections. These risks and uncertainties include, but are not limited to, those described in Item 1A, Risk Factors, and elsewhere in our annual report on Form 10-K, filed with the Securities and Exchange Commission, and those described from time to time in the other reports which we file with the Securities and Exchange Commission. It is now my pleasure to turn the call over to Mr. Jerrell Shelton, Chief Executive Officer of Cryoport. Jerry, the floor is yours.
Jerrell Shelton (CEO)
Thank you, Todd. Good afternoon, ladies and gentlemen. We appreciate your joining our earnings call today. With us this afternoon is our Chief Financial Officer, Robert Stefanovich, our Chief Scientific Officer, Dr. Mark Sawicki, and our Vice President of Corporate Development and Investor Relations, Thomas Heinzen. As a reminder, we have uploaded our second quarter 2023 in review document to our website. It can be found under the investor relations in the events and presentation section. This document provides a review of our financial and operational performance and a general business outlook. If you have not had a chance to read it, I would encourage you to download it at this time. I will provide you with a brief update on the business, and then we will move on to answering your questions.
Today, we reported second quarter revenue of $57 million, which was in line with the guidance that we had previously furnished. Our second quarter results reflected significantly weaker than expected demand for capital equipment from China and lower than expected ramps from certain clients during the second quarter. Specifically, China's economic condition and a significant drop in orders caused a second-quarter decline in MVE Biological Solutions, China-derived revenue of 67% or $5.8 million year-over-year. For the previous two years, the Chinese market has represented approximately 23% of MVE's total revenue and 10% of Cryoport's overall revenue. Based on our most recent conversations with our clients, as well as third-party sources, we expect these slowdowns to persist through the third and possibly the fourth quarter of this year.
Given this, after thorough consideration, we revised our full year financial forecast, with revenue now expected to be in the range of $233 million-$243 million for 2023, as previously communicated. While this is disappointing in the short term, we have been working actively to mitigate the situation and serve our clients' changing needs. Our leadership team has been meeting with key partners and distributors. Management has recently been to China to meet with our MVE team based there, along with key clients and distributors, with the objective of reinforcing our strengths and relationships. As a part of this effort, we have devised mitigation plans we believe will help to build our MVE long-term market-leading position.
I also want to be very clear that we have confidence in our corporate strategy and that our long-term growth drivers are firmly intact despite these short-term challenges. We operate in a very resilient industry, as life sciences treatments are a critical need, and we have a very pivotal role in serving this industry. We are a clear leader in providing solutions to support life-saving cell and gene therapies, and today's commercially approved therapies represent the tip of the iceberg. Despite any short-term headwinds, we expect to benefit from the continued growth of the cell and gene therapy industry, which is expected to grow at a 10-year compounded annual growth rate greater than 20%. In addition to the positive dynamics of the cell and gene therapy market, we are continuing to make strategic investments and form relationships to further enhance our growth prospects.
You can find further details on these investments and relationships in our second quarter 2023 in review document, which I mentioned earlier. We believe our growth prospects are stronger than ever, and we will continue to cement our leadership position in the cell and gene therapy industry as we move through current macroeconomic challenges that impacted our second quarter results. We are resolved to further strengthen our business and continue to position Cryoport for the long term and profitable growth.
This concludes my prepared remarks. Now we will be happy to take your questions. Operator, please open the line for questions.
Operator (participant)
Thank you. Ladies and gentlemen, we will now begin the question-and-answer session. Should you have a question, please press the star followed by the one on your touchdown phone. You will hear a three tone prompt acknowledging your request. Questions will be taken in the order received. Should you wish to cancel your request, please press the star followed by the two. Your first question is from Puneet Souda from Leerink Partners. Please ask your question.
Jerrell Shelton (CEO)
Hello, Puneet?
Mike Almisry (Equity Research Associate)
Hello?
Mark Sawicki (Chief Scientific Officer)
Yeah, there you are, Puneet.
Mike Almisry (Equity Research Associate)
Sorry, are you able to hear me?
Jerrell Shelton (CEO)
Yes, we can.
Mike Almisry (Equity Research Associate)
Okay. Yeah, you have Mike on for Puneet. For the first question, I was just wondering if you could elaborate a little bit on the investments you're making for the business. I saw there was a bit of a jump sequentially in the G&A. I'm wondering if that's, like, related to IntegriCell or other specific investments you're making.
Robert Stefanovich (CFO)
Yeah, we're making a number of investments here. You're absolutely correct. They're both in technology as well as building out our overall capabilities. You know, one of them is IntegriCell, where we're building out centers of excellence, both in Europe and Belgium, that's tied to the acquisition of Cell Matters in 2022, as well as the Center of Excellence in Houston, where we already have, you know, significant capabilities, and we're building it out to include IntegriCell solutions platform. Yeah, both of those are expected to be fully operational in Q1 of 2024. You know, these investments are all really based on the market insight that we have, which really includes detailed forecasts from our cell and gene therapy customers.
We're building out capabilities to expand market share as well as wallet share, you know, from our customer base.
Mike Almisry (Equity Research Associate)
Got it. Thank you. For my other question, I was wondering if you could offer a little bit of clarity about the impact from one of your customers' ramp. I was just wondering if that's something that's been resolved and if that's something we should take in consideration when thinking about the commercial therapy revenue for the rest of the year?
Robert Stefanovich (CFO)
It's, yeah, it's just. Obviously, as these guys gear up, they have things like temporary shutdowns for, you know, manufacturing purposes and other things. In the second quarter, we had a one of our commercial partners did have a shutdown for a period of time to do maintenance on it. That's a transient issue.
Mark Sawicki (Chief Scientific Officer)
Yeah, it was a planned shutdown.
Robert Stefanovich (CFO)
Yeah.
Mark Sawicki (Chief Scientific Officer)
For maintenance, calibration, and cleaning, and they're back up and running.
Robert Stefanovich (CFO)
Right.
Mike Almisry (Equity Research Associate)
Got it. Thank you very much.
Mark Sawicki (Chief Scientific Officer)
You're welcome.
Operator (participant)
Your next question is from David Saxon from Needham. Please ask your question.
David Saxon (Managing Director and Senior Equity Research Analyst)
Hi, good afternoon, and thanks for taking my questions. Maybe to start on, on the guidance, it looks like you lowered the guide by $32 million at the midpoint. That's excluding the second quarter miss, but I guess multipart question here. First, can you just break down the components of, of, you know, how the guide goes down? I'm assuming a lot of that is MVE, but, you know, we'll you fill in the details there. Second part of the question is just on the cadence in the back half. I mean, it doesn't sound like MVE trends in China are improving at all. Should we think of, you know, you guys facing somewhere in the $10 million-$12 million headwind in the third quarter?
You know, maybe you can offset that some, but, you know, should we shake out kind of in the low $50 million range, for third quarter? Then I'll have a follow-up.
Mark Sawicki (Chief Scientific Officer)
Yeah, no, look, the revised guidance that we had previously announced, you know, is obviously still intact. We took a very conservative approach to providing guidance with kind of the knowledge and experience that we have from Q2, that certainly does take into account, you know, the current economic issues that, you know, weak demand that we're experiencing within China. That's already baked into, you know, the guidance for the full year. Definitely we expect, you know, from a guidance perspective, you know, the MVE revenue to come in even a little bit lower than Q2. Again, I'm talking about guidance, not in terms of, you know, what we may, you know, internally see.
Then, you know, for the other businesses, again, we took a conservative approach where we're looking into just gradual increases, you know, for the services side of our business.
David Saxon (Managing Director and Senior Equity Research Analyst)
Okay. All right, so it's, I mean, it's, you know, low 50 is a good placeholder. Then I'll just ask my follow-up here. Jerry, you mentioned mitigation plans following the visit to China. Just, you know, maybe some color on, you know, what initiatives you're working on, and what kind of benefit you could see from those in the future. Thanks so much.
Jerrell Shelton (CEO)
Yeah. There are a couple of things that we're working on in with China. Number one is the general economic condition. We're strengthening our operation there, operationally. The most important thing is most likely the 2025 initiative that's underway to buy in China.
We're going to participate in that. We'll be manufacturing stainless product there eventually. We'll start off within six months of kitting those products and sending them to China so that they're manufactured in China. That will help us with market share there. Within two years, we'll be manufacturing and sourcing the materials in China, building up that China, China operation. We've needed to do this for some time. This, this economic pullback has just facilitated us and it helped us accelerate that plan. We have a vast market in China. We're going to be-- and it's a growing market, and we're going to be claiming more, more share in that market.
Mark Sawicki (Chief Scientific Officer)
Robert, do you wanna comment on the third quarter? You've had to ask-
Robert Stefanovich (CFO)
Yeah, no, I think in third quarter, you're right. I think, yeah, for your modeling, I think, yes, that's what I would assume.
David Saxon (Managing Director and Senior Equity Research Analyst)
Okay, great. Thanks so much.
Jerrell Shelton (CEO)
You're welcome.
Operator (participant)
Thank you. Your next question is from John Sourbeer from UBS. Please ask your question.
Lucas Beaumont (Associate Analyst)
Yeah, this is Lucas on for John Sourbeer here at UBS. I, I guess my first question is on MVE. Thinking about it, since acquisition, the performance has been a bit mixed. Do you think Cryoport currently has the right portfolio of assets, or could there potentially be some opportunities to divest some things? Thank you.
Jerrell Shelton (CEO)
John, we absolutely have the right portfolio of assets. MVE is a solid business. It's run by an excellent management team. It is the global leader throughout the world, and it is poised to benefit from the mountain of new approvals that are coming in cell and gene therapy. That will drive it very largely. It's a well-run company, fits in the portfolio, very profitable, produces cash flow. It's a company that you want to own and MVE is a solid company. You know, it's one of the assets that we think will benefit from what's coming.
Robert Stefanovich (CFO)
Maybe just to add to it, you know, in 2022, you know, MVE had over $22 million in, in free cash flow. It maintained good profitability levels, even in Q2 of this year, in spite of the, you know, weakened demand from the Chinese market.
Jerrell Shelton (CEO)
Yeah, and John, I think you need to recognize its strategic importance to us. I mean, this we're the leader in cryogenic systems throughout the world, in every region of the world. Cell and gene therapy will be providing tons of, mountains of approvals, you know, to come and hundreds of millions of dollars of opportunity. The industry will be gearing up. We have the number one source of supply for cryogenic systems, and that means also that we have the internal source, that is the supply chain, the supply support for our other companies. So there's an insurance component to it, as well as a, an offensive market gain component.
Lucas Beaumont (Associate Analyst)
Thank you. That's good color. Then I guess switching over to Cryoport Systems and some of the delays you saw there in the clinical trial business, I mean, were those more from large pharma, emerging biotech or both?
Robert Stefanovich (CFO)
No, so we did have an increase in clinical trial count this quarter, which was a nice step up versus last quarter. It takes time for those to ramp once they initiate. The drawdown that we saw last quarter as it relates to numbers, was more heavily weighted to the smaller, scale folks, not the large entities.
Lucas Beaumont (Associate Analyst)
Thanks. That's all I had.
Jerrell Shelton (CEO)
Thanks, Lucas.
Operator (participant)
Thank you. Your next question is from David Larsen from BTIG. Please ask your question.
David Larsen (Managing Director and Senior Healthcare IT and Digital Health Analyst)
Hi. beyond China, in other regions of the world, how is demand for MVE? I'm assuming the slowdown in demand is really for the large freezers. Is that correct or not? How is demand for the dewar and the small freezers in regions, beyond China, in like Europe and the U.S.? Thank you.
Jerrell Shelton (CEO)
The demand for dewars is primarily from the breeder community and it's strong. It hasn't fallen back. That's the supply of protein, so it's solid. The demand for freezers is around the world. It's a universal pullback, with the biggest pullback being in China.
Robert Stefanovich (CFO)
Yeah, maybe I can just add a little bit of color to it. If you look at, you know, China is by far the most significant. You know, in the EMEA region, you know, we had, you know, a decreased quarter-over-quarter last year, about 15%, in the U.S., about 9%. Compared to the impact on China and specific, and to some extent, Asia Pac, you know, the other two markets are, are still pretty solid.
David Larsen (Managing Director and Senior Healthcare IT and Digital Health Analyst)
Okay. Then, Jerry, it sounds like you visited with China, and I'm assuming you met with some folks, and it seems like you're investing even more in that region going forward. That's part of your mitigation strategy. You know, I'm kind of assuming that the only reason you'd be investing more is if you had some sort of a sense that there would be revenue coming from that area in the future. I mean, were there any sort of verbal commitments as part of your con, you know, ongoing and increased investments in that country despite the economic challenges?
Mark Sawicki (Chief Scientific Officer)
One of the things you have to think about when you look at that is what's going on in the cell and gene space. China has eclipsed Europe as the number two entity for clinical activity, in the cell and gene space, and is actually projected in the next three years to eclipse the United States in activity. There's a significant substantial pipeline and resource that's going to be required that will need cryogenic equipment, from both a distribution and storage standpoint. Yeah, there's a lot of data behind that supports that strategy.
Thomas Heinzen (VP of Corporate Development and Investor Relations)
I think one thing, Dave, that just to tag on to Mark's comments real quick, there is a initiative in China in 2025 for the companies in China to buy equipment only made by companies in China. So that's one of the drivers we're already moving on, is to manufacture MVE equipment in China for China.
Robert Stefanovich (CFO)
Correct.
Thomas Heinzen (VP of Corporate Development and Investor Relations)
That's part of that initiative.
David Larsen (Managing Director and Senior Healthcare IT and Digital Health Analyst)
Okay, just one more question in this area. Is China largely a self-contained region, or I think you mentioned, like, steel and other products that you'll be producing in China, are those also going to be supplying other regions like the U.S. and Europe? Will you be dependent on what's manufactured in China for the rest of the business, or is it going to be largely self-contained?
Jerrell Shelton (CEO)
China is already an export of part of our company. We export out of China to EMEA and to the Americas. We look at all of our plants as at manufacturing at the same quality level. They, all the products are you know, interchangeable. Quality is high, and the reach is broad.
Thomas Heinzen (VP of Corporate Development and Investor Relations)
Just to remind you, Dave, we have three manufacturing facilities, two in the United States and one in China. The United States facility in Minnesota makes the dewars, the aluminum dewars, for the United States and around the world. The Ball Ground, Georgia, facility manufactures the freezers for the United States and EMEA, mostly. Does that help?
David Larsen (Managing Director and Senior Healthcare IT and Digital Health Analyst)
Yeah, that's very helpful. Thanks very much. I'll hop back in the queue.
Thomas Heinzen (VP of Corporate Development and Investor Relations)
Thanks, Dave.
Jerrell Shelton (CEO)
Thanks.
Operator (participant)
Thank you. Your next question is from Yuan Zhi, from B. Riley. Please ask your question.
Yuan Zhi (VP and Equity Research Analyst)
Thank you. Thank you for taking our questions. I think most of my question has been answered, but Jerry, can you maybe talk about the expansion opportunity for CRYOPDP, and do you see the opportunity or synergy with MVE in China? Thank you.
Jerrell Shelton (CEO)
So if I understand your question, it was the opportunities and expansion of CRYOPDP in China.
Yuan Zhi (VP and Equity Research Analyst)
Correct. Just broadly on the expansion opportunity for CRYOPDP and then synergy with MVE in China.
Jerrell Shelton (CEO)
Yeah. So we're doing our rec and order. We're doing our rec and order with Cryo PDP in China. We've looked at acquisitions. We know the opportunity is there. We do some business there now, both with Cryo PDP and Cryoport Systems. It accounts for 1.5 billion people in this world, and the lands, and it operates, that, just the Chinese government operates very differently than any other part of the world. As Mark said, there's an enormous opportunity. You can expect some future activity in China from Cryo PDP and Cryoport Systems. There's no way we can avoid that part of the world.
As Mark said, you know, the China is forecast to eclipse the United States in cell and gene therapy, in the next, within the next, decade.
Robert Stefanovich (CFO)
I think you were, on CRYOPDP, you were also looking for, you know, just broader outside of China, just, you know, activities. Something that we've talked about before is really CRYOPDP's strength in Europe and Asia Pac, that continues, but also our intent to build out their U.S. capabilities. That's actively in the works and we see a lot of synergy opportunities between Cryoport Systems and CRYOPDP in particular, with the U.S. customer base that Cryoport Systems has.
Jerrell Shelton (CEO)
All of this is the working to build out, to take advantage of those approvals that are coming. Our business is a lot like biologics, were, the biologics history. If you looked at biologics in 2010, it was around $40 billion. Today, it's $475 billion in revenue, and it just sprung out. This is a similar situation, so we're preparing all of the time for the future. We have seven potential approvals coming this year, and it's an exciting time. five. Okay, I'm corrected. Five potential approvals.
Robert Stefanovich (CFO)
We have two already, two already approved this year.
Jerrell Shelton (CEO)
Two already approved. Okay. Thank you.
Yuan Zhi (VP and Equity Research Analyst)
Got it. Thanks for the clarification.
Robert Stefanovich (CFO)
Thank you.
Operator (participant)
Thank you. Once again, ladies and gentlemen, that is star one should you wish to ask a question. Your next question is from Richard Baldry, from Roth MKM. Please ask your question.
Richard Baldry (Managing Director and Senior Research Analyst)
Thanks. I'm just curious if you can give an update on the, I'll miss the technical term, but the blood collection standardization initiative. Is there any timing for launch? You know, where you're standing on that?
Mark Sawicki (Chief Scientific Officer)
Yep, we're making great progress. The facilities in Houston are construction complete. We're-- We've initiated the validation and qualification activities for the process as well as all the equipment. The site in Belgium is running a month or two behind that. Both are anticipated to be ready for launch and start to generate revenue in Q1 of next year. Things are running very, very smoothly. We've already-- Similar to the BioServices entity, when we opened those last year, we already have folks coming through from our client base, substantial number of them that are pre-evaluating the infrastructure, the facilities, and the processes to fast track their audit processes, which we think will provide a very, very strong, quick start there once we open for business next year.
Jerrell Shelton (CEO)
I'd like to remind you that, you know, all of these efforts are, again, preparing for the future, the market that we know is coming. When a market is coming like this, there's, there are needs for standardization. IntegriCell is built from market demand. It's not built just on a whim. It's being built for scale.
Richard Baldry (Managing Director and Senior Research Analyst)
Thanks. If you look at sort of the newer offerings, across your things, whether that's the Elite shippers, the Elite Ultra Cold and Cryosphere, or even the Cryoportal 2.0, how do you think that changes your go-to-market pricing? Is it sort of a new higher tier? Does it just replace what's there as is? How do we think about the economics as you make those shifts?
Jerrell Shelton (CEO)
I'll turn it over to Mark in just a second, because to add to this, but, you know, the Elite line of shippers is composed of the Cryosphere and the Elite Ultra Cold. Elite Ultra Cold is at minus 80. It opens up the whole gene market to us, because generally speaking, not always, but generally speaking, gene therapies require minus 80 degrees Celsius. That's what the Elite Ultra Cold is. The Elite Ultra Cold also has features and benefits that no one else has in the market by a long shot. I mean, it has a whole time, twice as much as its nearest competitor, and then it has the all the monitoring that we provide, along with the Cryoportal control, the logistics network and our fantastic logistics technicians supporting the shipments.
It's a revolutionary product, and it's one that Sarepta is using, for example, in their launch of, of their new gene therapy. Then, of course, the Cryosphere is the other part of the Elite line. The Elite line stands out in a much in a very poignant way from other competitors in the marketplace. Do you want to add anything, Mark?
Mark Sawicki (Chief Scientific Officer)
I think Jerry covered it really well. You know, if you guys are thinking about it from an economic standpoint, you know, there will be a slight premium associated with it, you know, that, that you guys may want to, from a modeling standpoint, may want to consider. As Jerry had mentioned, these are premium products in the space. They're meant to be differentiators. You know, obviously, the Ultra Cold is a new product line for us and allows us to extend into the gene therapy space and capture aspects of the market that we didn't have accessibility to previously, which will allow us to continue to build share overall.
Richard Baldry (Managing Director and Senior Research Analyst)
Thanks. Can you maybe, you know, do sort of the same peel back on the Cryoportal 2.0, sort of as a, is it just a replacement or an upgrade? Then maybe there's a decent step up on an acquisition integration cost in the quarter and kind of look underneath the hood on that too. Thank you.
Jerrell Shelton (CEO)
I'm going to turn the question on the integration cost over to Robert in just a moment. To your question. What was the question?
Mark Sawicki (Chief Scientific Officer)
The Cryoportal.
Jerrell Shelton (CEO)
Oh, to your question about the Cryoportal two. Cryoportal two is the only logistics management system, to my knowledge, in the industry that is 21 CFR Part 11 compliant. It's GAAP validated. It sets us apart from anyone else in the industry in terms of information and security, and speed and comprehensiveness. It also gives us a platform for expansion and adding other services in the future. You want to add anything to that, Mark?
Mark Sawicki (Chief Scientific Officer)
Yeah. One of the things you have to think about when you're looking at the Cryoportal two is it does. There's a couple of fundamental differences here. First and foremost, is it provides a readily made vehicle for integration with third-party systems and competencies. Data is gonna be a huge driver in this space moving forward, and this provides the ability to more effectively transfer and manage data, and it also allows us to start to monetize the data that we have in our system. We're gonna be initiating, and we already have, in some cases, a data services platform that will allow us to start to monetize that data moving forward, which is a step change from the historical portal.
Robert Stefanovich (CFO)
Yeah, just to your second question related to the acquisition-related costs. You know, we did explore a strategic acquisition opportunity during the first half of this year, but ultimately decided not to move forward with that. You know, the costs that we had are just, you know, customary due diligence and market research activities. Having said that, you know, we are actively looking at smaller tactical acquisition opportunities globally, you know, similar to what we have done in the past. Kind of that's where we stand as of now.
Richard Baldry (Managing Director and Senior Research Analyst)
Thanks.
Operator (participant)
Thank you. Your next question is from Brandon Couillard, from Jefferies. Please ask your question.
Brandon Couillard (Managing Director and Senior Equity Research Analyst)
Thanks. Good afternoon. A couple more on MVE, if you don't mind. The two key revenue decline, is that all unit volume, or are you seeing some pricing pressure as well? Specifically within China, how sure are you that it's macro and not a local competition dynamic? Third question, what % of the MVE business was China in 2020 when you bought it, if you have that, thanks.
Jerrell Shelton (CEO)
I'll give the % to Brandon, to the % to Robert in just a moment. We're certain that it wasn't competition. We have a lot of intelligence going on around competition, especially in China. We're certain of that.
Robert Stefanovich (CFO)
Yeah, and you know, China-derived sales for MVE were you know, in the 19%-20%. And I make that distinction of China-derived, because you look at the region. We looked at for this analysis, really at our distributors, our sales within China, our distributors outside of the China, where the end destination of the products is China, as well as our direct customers, whether it's in the U.S. or elsewhere, where their end destination is China. We try to really capture all of the China impact in that number, but about, you know, a little bit less than 20%.
Brandon Couillard (Managing Director and Senior Equity Research Analyst)
Got you. Okay. Second question, just on the number of clinical trials you added in the second quarter. I thought when we talked a month ago, you were actually seeing some revenue impact from trials being terminated, some cancellations, some reprioritization, but you added, you know, a lot in the quarter. Do you happen to have the breakdown of, of number of terminations or completions versus gross adds? How do we kind of reconcile, you know, those two data points?
Mark Sawicki (Chief Scientific Officer)
Yep. We absolutely did in Q1 see a substantial number of terminated. We actually had 37 terminations in Q1. That number has dropped to 16 in Q2 from a termination standpoint. That, the 27 in Q1 obviously impacted the softness from a revenue standpoint in Q2, because those programs weren't running. We did have a nice add in the second quarter, but those trials don't start at full enrollment. You know, you initiate those trials, they come online, but they take a couple of quarters to really ramp. That obviously bodes well for the future, but it doesn't. There is a lag period between onboarding and obviously full activity and revenue contribution.
Brandon Couillard (Managing Director and Senior Equity Research Analyst)
Got you. Last one. A competitor recently, you know, earlier this week, said it's increasingly clear to them that late stage and approved cell and gene companies are looking to multi and dual source their logistics providers. Just would like to get an, you know, update from your point of view on that dynamic and what that mix, you know, could really look like as you see it on the ground today. Is it 50/50 share, or are they keeping a second vendor just warm and maybe you retain 80%, 20% of the business? How do you see that trend, I guess, today and going forward?
Mark Sawicki (Chief Scientific Officer)
Yeah, obviously, we'll always have some competition in the space. In particular, cell and gene space is rapidly growing and will continue to expand at a rate that's disproportionate to the overall industry. This is going to run for the foreseeable future. You know, I'll put our solutions up against anyone else in the space at any time. We have been very successful and captured nearly 70% of the market due to the fact that we are best in class. We have exemplary performance, we are building for scale. You know, this reputation is unsurpassed and has allowed us to capture that 70% market share.
We feel very confident that our that our solution will continue to dominate in the market, both the clinical and the commercial markets, for the foreseeable future.
Brandon Couillard (Managing Director and Senior Equity Research Analyst)
Very good. Thank you.
Operator (participant)
Thank you. There are no further questions at this time. I will now hand the call over back to your speakers for the closing remarks.
Jerrell Shelton (CEO)
Thank you for your questions and our discussion. In closing, the second quarter was challenging, but Cryoport is continuing to execute on its plans to position our company as a value-added provider and vital resource serving the cell and gene therapy industry, which is poised for substantial growth as it transforms the way medicine is practiced. We're doing so by making targeted investments, introducing important new services and products, and forming key strategic relationships. We believe all these actions combined will make us stronger, more efficient organization, and ultimately support our company's long-term growth. We want to thank you for joining us today. We appreciate your continuing support and interest in our company. We look forward to updating you on our progress again next quarter, when we report on our third quarter 2023 results. Good night.
Operator (participant)
Thank you. Ladies and gentlemen, the conference has now ended. Thank you all for joining. You may all disconnect.