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Ramkumar Mandalam

Lead Director at Cryoport
Board

About Ramkumar Mandalam

  • Independent director (since June 2014), currently Lead Director; Chair of the Compensation Committee; member of the Audit, Nominating & Governance, and Science & Technology Committees .
  • Age 60; Ph.D. in Chemical Engineering, University of Michigan; founder/CEO of Citra BioConsulting (since 2021); prior CEO/President and director at Cellerant Therapeutics; earlier leadership roles at Geron and Aastrom Biosciences; author/co-author of publications and patent filings .
  • Board independence affirmed by the company (NASDAQ Rule 5605(a)(2)); five of six directors are independent .
  • Board/committee attendance: in 2024, each director attended at least 75% of Board and committee meetings; Board met five times in 2024 .

Past Roles

OrganizationRoleTenureCommittees/Impact
Cellerant Therapeutics, Inc.CEO, President, and Board Member~2005–2021 (prior to founding Citra BioConsulting in 2021)Led pipeline development in hematologic malignancies; grew company from early stage to advanced clinical stage
Geron CorporationExecutive Director of Product DevelopmentPrior to 2005Managed development/manufacturing of cell-based therapies
Aastrom BiosciencesR&D roles1994–2000Led programs for ex vivo expansion of bone marrow stem and dendritic cells

External Roles

OrganizationRoleTenureNotes
Citra BioConsulting Inc.Founder & CEO2021–presentConsulting firm serving cell & gene therapy industry
NSF Center for Cell Manufacturing Technologies (CMaT)Commercial Advisory Board MemberNot disclosedAdvisory role
Stempeutics Research Pvt. Ltd.Board MemberNot disclosedDisclosed in 2024 proxy biography

Board Governance

  • Roles and independence: Lead Director (independent); Chair, Compensation Committee; member of Audit; Nominating & Governance; and Science & Technology committees; board independence confirmed .
  • Committee activity (2024): Audit (5 meetings; members: Baddour—Chair, Hancock, Mandalam); Compensation (5 meetings; Mandalam—Chair, Hancock, Baddour); Nominating & Governance (5 meetings; Baddour—Chair, Hariri, Mandalam); Science & Technology (2 meetings; Hariri—Chair, Hancock, Mandalam) .
  • Board activity (2024): Five board meetings; ≥75% attendance for each director; company maintains independent Lead Director structure and independent evaluation of CEO by independent directors .
  • Overboarding policy: Without specific Board approval, limit of ≤3 public company boards per director (≤2 if serving as a public-company executive) .
  • Insider trading, hedging/pledging and clawback: Prohibits hedging/pledging of company stock; robust Nasdaq-aligned clawback policy .

Fixed Compensation (Non-Employee Director Pay)

Component20232024Notes
Annual cash retainer (standard)$70,000 $70,000 Company-wide director plan
Lead Director fee$25,000 $25,000 Applies to Lead Director
Compensation Committee Chair fee$15,000 $15,000 Applies to Chair
Other chair fees (for reference)Audit Chair: $20,000; N&G Chair: $10,000; S&T Chair: $24,000 Same schedule Not applicable to Mandalam except Comp Chair
Cash fees actually earned – Mandalam$80,000 $85,616 Reflects role-based fees and timing

Director stock ownership guideline: 3x annual retainer; all non-employee directors were compliant or within time window to comply as of the record date .

Performance Compensation (Equity for Directors)

Equity ElementValue/Grant DesignVestingPost-Service Terms
Annual stock options$162,500 grant-date value Vest monthly over 1 year; strike at closing price on stockholder meeting date Vested options lapse at earlier of 7 years or 3 years after leaving Board
Annual RSRs$162,500 grant-date value One-year cliff vest from annual meeting date N/A
Sign-on options (new directors)$200,000 value Vest monthly over 3 years Same post-service option terms
Sign-on RSRs (new directors)$200,000 value Vest annually over 3 years N/A

Mandalam’s equity received (as reported):

  • 2023: Stock awards $162,505; Option awards $162,500; Total director comp $405,005 .
  • 2024: Stock awards $162,499; Option awards $162,489; Total director comp $410,604 .

Note: Director equity is service-based (no explicit performance metrics). The company prohibits option repricing and hedging/pledging, and uses independent compensation consultants; has clawback and ownership guidelines .

Other Directorships & Interlocks

TypeCompany/EntityRoleNotes
Public company boardsNone disclosed for MandalamNo current public directorships listed in the 2025 proxy biography
Private/AdvisoryCMaTCommercial Advisory BoardAdvisory role
PrivateStempeutics Research Pvt. Ltd.DirectorDisclosed in 2024 proxy
Compensation committee interlocksNoneCompany disclosed no interlocks/insider participation concerns for 2024 and 2023

Expertise & Qualifications

  • Deep cell and gene therapy domain expertise; prior executive and development leadership across Cellerant, Geron, and Aastrom; scientific credentials and IP/publications record .
  • Lead independent governance role plus chairmanship of Compensation Committee signal material influence on incentive design and oversight .

Equity Ownership

ItemDetail
Beneficial ownership (as of April 14, 2025 record date)337,849 shares; <1% of outstanding
Shares acquirable within 60 days (options/RSRs per footnote)291,197 shares
Unexercised options (as of 12/31/2024)282,519 options
Unvested RSRs (as of 12/31/2024)12,845 RSRs
Director ownership guideline3x annual retainer; compliant or on track
Hedging/PledgingProhibited by policy

Insider Trades and Section 16 Compliance

ItemDisclosure
Section 16(a) filing compliance (2024)Company noted certain late filings for Shelton, Stefanovich, Sawicki, and Hariri; no exceptions noted for Mandalam

Governance Assessment

  • Strengths and positive signals

    • Independent Lead Director with multi-committee service and Compensation Chair role enhances oversight of pay practices and management accountability .
    • Board/committee engagement: Mandalam’s committees (Audit, Compensation, N&G, S&T) were active in 2024 (5/5/5/2 meetings respectively); Board met five times, with ≥75% attendance per director .
    • Shareholder-aligned guardrails: anti-hedging/pledging policy; robust clawback; no option repricing; no single-trigger CIC; director ownership guidelines (3x retainer) with compliance .
    • No related-party transactions disclosed involving Mandalam; Audit Committee oversees related-party review .
    • Overboarding policy limits external commitments, supporting director effectiveness .
  • Watch items (no current red flags disclosed)

    • External consulting CEO role (Citra BioConsulting) in cell/gene therapy arena: while no related-party dealings disclosed, remain attentive to any future engagements that could interface with Cryoport’s life sciences logistics ecosystem; independence is affirmed by the Board .
    • Ownership is <1% but supported by meaningful option holdings and guideline compliance; continue monitoring ownership alignment over time .
  • Director compensation mix and trend

    • Stable equity-heavy mix year over year (stock awards ~$162.5k; options ~$162.5k), with modest increase in cash fees in 2024 ($85,616 vs. $80,000) likely reflecting leadership roles and plan design; plan prohibits repricing and encourages alignment via vesting and ownership guidelines .

Overall: Governance posture for Mandalam is investor-friendly—independence is clear, engagement is high across critical committees, and key risk controls (anti-hedge/pledge, clawback, ownership) are in place. No disclosed conflicts or interlocks; compensation oversight leadership is a positive for pay-for-performance alignment .