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Wendell Wierenga, Ph.D.

Director at CYTOKINETICSCYTOKINETICS
Board

About Wendell Wierenga, Ph.D.

Independent Class I director of Cytokinetics (CYTK), age 77, serving since February 2011. Ph.D. in Chemistry from Stanford University and B.A. from Hope College; over three decades of senior R&D leadership and biotech governance experience across Upjohn, Parke‑Davis/Warner‑Lambert, Syrrx, Neurocrine, Ambit, and Santarus . The Board has affirmatively determined he is independent under Nasdaq and SEC rules . CYTK’s Board met 10 times in 2024; all directors attended at least 75% of Board and committee meetings .

Past Roles

OrganizationRoleTenureNotes/Committees/Impact
Upjohn PharmaceuticalsResearch & drug discovery roles, Executive Director of Discovery Research~16 years (prior to 1990)Built discovery capabilities
Parke‑Davis/Warner‑Lambert (now Pfizer)SVP Worldwide Pharmaceutical Sciences, Technologies & Development1990–2000Global development leadership
Syrrx, Inc. (now part of Takeda)Chief Executive Officer2000–2003Led structure‑based drug discovery company
Neurocrine BiosciencesEVP Research & Development2003–2006Advanced R&D programs
Ambit BiosciencesEVP Research & Development2006–2011Oncology/kinase programs
Santarus (acquired by Salix; then Valeant)EVP Research & Development2011–2014Late‑stage and commercial R&D oversight

External Roles

OrganizationRoleTenurePublic/Private
Crinetics PharmaceuticalsDirectorSince 2014Public
Dermata TherapeuticsDirectorSince Sept 2016Public
Onyx PharmaceuticalsDirector1996–2013Public (historical)
XenoPortDirector2001–Aug 2016Public (historical)
Ocera TherapeuticsDirectorDec 2013–Dec 2018Public (historical)
Anacor PharmaceuticalsDirectorSept 2014–July 2016Public (historical)
Apricus BiosciencesDirectorMar 2014–Dec 2018Public (historical)
Concert PharmaceuticalsDirectorMar 2014–June 2019Public (historical)
Patara PharmaDirector2015–Nov 2018Private (historical)

Board Governance

AttributeDetails
Director ClassClass I
IndependenceIndependent (Nasdaq/SEC)
CommitteesCompensation & Talent (member); Nominating & Governance (member); Science & Technology (Chair)
Committee Meeting Cadence (2024)Compensation: 8; Governance: 9; Science & Technology: 4
Board Attendance≥75% of Board/committee meetings for all directors in 2024
Board StructureClassified board (staggered terms)
LeadershipBoard Chair: John T. Henderson; CEO separate from Chair

Fixed Compensation

Component2024 AmountNotes
Fees Earned or Paid in Cash$85,833 Overpayments for certain retainers to be offset in 2025; election possible to take base retainer in equity
Equity in Lieu of Cash Retainer (Shares)391 shares Under Equity‑in‑Lieu program
Per‑Meeting FeesNoneCYTK does not pay per‑meeting fees
Standard Annual Retainers (Policy Reference)Board Chair $85,000; other directors $50,000; Committee chair/member retainers per committee (e.g., Science & Tech Chair $25,000; Compensation member $10,000; Governance member $5,000) Policy schedule; individual totals depend on roles/elections

Performance Compensation

Grant DetailValue/TermsVesting/Features
Annual Option Award (May 15, 2024)Grant‑date fair value $239,826; exercise price $60.50 Options vest monthly over the year until next annual meeting; 10‑year max term per plan
Annual RSU Award (May 15, 2024)Grant‑date fair value $219,978 RSUs vest in one installment at one‑year or next annual meeting
Unvested RSUs (12/31/2024)3,636 units
Option Exercise Window Modification (Mar 2024)Incremental fair value recognized; Dr. Wierenga ≈$0.2 million included in option award value Extended post‑resignation exercise window based on years of service
Director Equity Policy (2024 practice)Continuing directors: mixed RSU + option grant, aggregate target ≈$440,000 Service‑based vesting; no performance metrics
Director Equity Limits (proposed 2025)Annual cap $1,000,000; onboarding cap $1,250,000 (subject to stockholder approval) Intended to mitigate self‑approval optics
Change‑of‑Control TreatmentIf not assumed/substituted: time‑based awards fully vest; performance‑based deemed at target; if assumed then director termination triggers full vesting

Other Directorships & Interlocks

ItemStatus
Compensation Committee Interlocks (2024)None; no member served on another company’s board/comp committee with CYTK executive overlap
External Public BoardsCrinetics Pharmaceuticals; Dermata Therapeutics (current)

Expertise & Qualifications

  • Deep R&D and discovery leadership across big pharma and biotech; former CEO (Syrrx) and multiple EVP R&D roles .
  • Chairs Science & Technology Committee; contributes to strategic R&D direction and regulatory strategy oversight .
  • Independent director with long tenure (since 2011) and multi‑company board experience .

Equity Ownership

MeasureAmount
Total Beneficial Ownership188,425 shares (less than 1%)
Directly Held Shares19,171 shares
Options Exercisable (within 60 days of 2/28/2025)169,254 shares
Hedging/PledgingProhibited by policy (no hedging/pledging allowed)
Stock Ownership PolicyDirectors required to maintain minimum ownership (policy exists; numeric multiple not disclosed in proxy)

Insider Trades

DateFilingTransactionNotes
Oct 28, 2024Form 4 (filed Oct 31, 2024)Sale transactionLate filing due to administrative error; company notes other late filings for certain executives in 2024

Governance Assessment

  • Board effectiveness: Wierenga chairs Science & Technology and serves on Compensation and Governance—positions aligned with his R&D depth; independence affirmed; attendance threshold met (≥75%) .
  • Director pay mix: Heavy equity component (options + RSUs) aligns incentives with shareholders; equity‑in‑lieu program reinforces ownership; no per‑meeting fees; policy‑level caps proposed to limit director equity values and mitigate self‑approval optics .
  • Conflicts/related‑party exposure: Proxy discloses related‑party transaction review policies; no specific related‑party transactions involving Wierenga are disclosed .
  • Committee risk oversight: Compensation Committee reviews compensation risk and uses independent consultant (Aon); no interlocks reported; science committee provides strategic R&D oversight .

RED FLAGS

  • Late Form 4 filing for a personal sale on Oct 28, 2024 (filed Oct 31, 2024); company attributes to administrative error—minor but noteworthy for compliance tracking .
  • Option exercise window extension for directors increased grant fair values (≈$0.2m incremental for Wierenga)—shareholder‑sensitive; Board offset by proposing formal annual caps on director equity .

Alignment signals

  • Significant option/RSU holdings and election to receive retainer in shares (391 shares) demonstrate skin‑in‑the‑game; hedging/pledging prohibited; stock ownership policy in place .