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William Rastetter

Chair of the Board at Dare BioscienceDare Bioscience
Board

About William H. Rastetter, Ph.D.

Independent director and Chair of the Board at Daré Bioscience since July 2019; director since January 2014. Age 77; education includes S.B. from MIT and M.A./Ph.D. from Harvard. Extensive biotech leadership (Biogen Idec/Idec, Venrock, Grail, Illumina) and current public board chair roles, with board-validated financial expertise .

Past Roles

OrganizationRoleTenureCommittees/Impact
Biogen Idec Inc.Executive Chairman (prior)Not disclosedExecutive leadership, industry credentials
Idec PharmaceuticalsChairman & CEO (prior)Not disclosedLed company through growth phase
Venrock AssociatesPartner2006–2013VC experience; portfolio governance
Illumina, Inc.Director; ChairmanDirector 1998–Jan 2016; Chairman 2005–2016Led board during scale-up; industry influence
Grail, Inc.Founding Director; Interim CEO & ChairmanFounded 2016; Interim CEO/Chair 2017–2018; Director until 2021Early-stage leadership; sale to Illumina in 2021
Receptos, Inc.Co-founder; Acting CEO; ChairmanActing CEO 2009–2010; Chairman 2009–2015Built and exited high-profile biotech
Genentech, Inc.Director of Corporate VenturesNot disclosedCorporate venture leadership
MIT; Harvard UniversityFaculty positions; Alfred P. Sloan FellowNot disclosedAcademic credentials

External Roles

OrganizationRoleStatusNotes
Neurocrine Biosciences, Inc.ChairmanCurrentPublic company; chair role
Fate Therapeutics, Inc.ChairmanCurrentPublic company; chair role
Regulus Therapeutics, Inc.DirectorCurrentPublic company board
Iambic, Inc. (private)DirectorCurrentAI-driven drug design
Illumina VenturesAdvisorCurrentVC advisor
San Diego Squared (non-profit)Co-founder & ChairmanCurrentSTEM workforce charity

Board Governance

  • Independence: Board determined all directors other than the CEO are independent under Nasdaq rules; Rastetter is independent .
  • Leadership: Chair and CEO roles separated; Chair sets agendas/materials; structure enhances objective oversight .
  • Committees and roles: | Director | Audit | Compensation | Nominating & Corporate Governance | |---|---|---|---| | William H. Rastetter, Ph.D. | — | Chair | — |
  • Meetings and attendance: Board met 11x in 2024; Audit 8x, Compensation 4x, Nominating 5x; all directors attended ≥75% of their meetings .
  • Strategic & Pricing Committee (for accelerated actions): Members are Kelley, Matz (Chair), Johnson, Steele; Rastetter not a member; committee met 3x in 2024 .
  • Audit Committee practice: Routine executive/private sessions each quarter; Matz designated “audit committee financial expert” .

Fixed Compensation

ComponentAmount/Term2024 Actual (Rastetter)
Board Chair annual retainer (cash)$69,000Included in fees
Compensation Committee Chair fee (cash)$10,000Included in fees
Committee membership fees (if any)Audit $7,500; Comp $5,000; N&CG $4,000N/A for Rastetter beyond chair role
Equity – Annual stock option grant3,333 shares (2024); vests at next AGM or 1-year; COC accelerates; strike at grant FMV Grant-date fair value $12,945
2024 Director compensation – Cash fees$79,000Paid in cash; directors may elect stock in lieu of cash
2024 Director compensation – Total$91,945Cash + option award
Expense reimbursementReasonable travel/meeting expensesStandard policy
  • 2025 changes: Non-employee director retainer increased to $40,000; annual option grant raised to 4,500 shares (initial award scaled to maintain 1.5x multiple), per Aon benchmarking .

Performance Compensation

  • No performance-based director pay disclosed (options are time-based vesting and accelerate upon change-in-control; no PSUs/RSUs for directors). | Performance metric linkage to director pay | Status | |---|---| | Cash retainer tied to targets | None disclosed | | Equity award vesting tied to performance (TSR/financial) | None; time-based vest; COC acceleration |

Other Directorships & Interlocks

CompanyIndustryRolePotential interlock/conflict notes
Neurocrine BiosciencesBiopharmaChairmanMultiple concurrent chair roles; no related-party transactions with Daré disclosed
Fate TherapeuticsBiopharmaChairmanSame as above
Regulus TherapeuticsBiopharmaDirectorNo related-party transactions disclosed
Iambic (private)AI drug discoveryDirectorPrivate; no transactions disclosed

Expertise & Qualifications

  • Biotech operating and board leadership; capital markets and “financial matters” experience per board biography .
  • Extensive governance experience across public boards; prior VC and corporate venture roles .
  • Academic pedigree: MIT SB; Harvard MA/PhD; Sloan Fellow .

Equity Ownership

HolderBeneficial shares% outstandingNotes
William H. Rastetter, Ph.D.21,182<1%Includes 20,323 shares issuable upon exercise of stock options; outstanding shares held by Rastetter Family Trust U/A 09/02/2010; co-trustee with shared investment/dispositive power
Options outstanding (director ledger, 12/31/2024)20,437As of year-end 2024, options to purchase this number of shares
  • Hedging/pledging policy: Company prohibits short sales, margin loans, and hedging devices for personnel (includes directors); as of proxy date no approvals sought for exceptions .

Governance Assessment

  • Positive signals:

    • Independent Chair separate from CEO; board-majority independence; committee chairs designated; regular evaluations; director education and external governance expert engagement .
    • Strong audit governance (financial expert designated; executive/private sessions) .
    • Director pay structure modest and aligned to equity via options; no repricing without stockholder approval; director equity grant cap $500,000; minimum vesting requirements; no evergreen; change-in-control treatment explicitly constrained .
    • Say-on-pay support 88% in 2024, indicating shareholder confidence in compensation oversight .
  • Monitoring items:

    • Overboarding considerations: concurrent chair roles at Neurocrine and Fate plus other boards—no attendance issues disclosed (≥75% met), but portfolio managers may monitor bandwidth and potential information flow dynamics across biopharma boards .
    • Related-party exposure: none disclosed for Rastetter; company-level related-party employment (CEO’s daughter) is overseen by the Audit Committee, not linked to Rastetter .
  • RED FLAGS: None disclosed specific to Rastetter (no legal proceedings, pledging, or related-party transactions; attendance threshold met) .

Overall, Rastetter’s independent chairmanship, compensation committee leadership, and broad biotech governance experience are supportive of board effectiveness; monitor multi-board commitments and maintain vigilance on change-in-control equity acceleration terms and director equity grant sizing in 2025 relative to dilution. **[1401914_0001401914-25-000014_dare-20250424.htm:12]** **[1401914_0001401914-25-000014_dare-20250424.htm:13]** **[1401914_0001401914-25-000014_dare-20250424.htm:41]** **[1401914_0001401914-25-000014_dare-20250424.htm:49]**