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Shari Lisa Piré

Director at PRECISION BIOSCIENCES
Board

About Shari Lisa Piré

Shari Lisa Piré, 60, is an independent director of Precision BioSciences (DTIL) serving since November 2021. She is Chief Legal & Sustainability Officer and Chief Privacy Officer at Plume Design, Inc., with more than 20 years advising public and private companies; she holds a B.A. in French Literature (UC Irvine) and a J.D., magna cum laude (New York Law School), and is admitted to the NY and D.C. Bars . The Board determined she is independent under Nasdaq rules .

Past Roles

OrganizationRoleTenureCommittees/Impact
Cognate BioServices, Inc.Chief Legal OfficerApr 2015 – Apr 2021Led and negotiated transactions culminating in sale to Charles River Laboratories
Cobra Biologics Ltd.Board MemberJan 2020 – Apr 2021Board service at gene therapy-focused CDMO acquired under her leadership at Cognate

External Roles

OrganizationRoleTenureCommittees/Impact
Plume Design, Inc.Chief Legal & Sustainability Officer; Chief Privacy OfficerMay 2021 – PresentServes on privacy governance committee overseeing cybersecurity

Board Governance

  • Board independence: Piré is one of five independent directors (out of six); Board leadership separated (independent Chair fulfills Lead Director functions) .
  • Committee assignments:
    • Nominating & Corporate Governance Committee: Chair
    • Compensation Committee: Member
  • Meetings and attendance (FY2024):
    • Board met 7 times; committees: Audit (4), Compensation (3), Nominating & Gov (2), Science & Tech (6). Each incumbent director attended ≥75% of Board and committee meetings; all directors attended the 2024 annual meeting .
  • Executive sessions: independent directors hold regular executive sessions; at least twice yearly exclude management/non-independent directors .

Fixed Compensation

ComponentAmountDetail / Basis
Annual Director Fee$40,000Standard non-employee director retainer
Committee Chair Fee (Nominating & Corporate Governance)$8,250Annual chair fee
Committee Member Fee (Compensation)$6,000Annual member fee
Total Fees Earned (2024)$54,250Reported fees for 2024

Performance Compensation

Equity AwardGrant SizeGrant-Date Fair ValueVesting Terms
Annual RSUs (2024)9,826$129,998Annual RSUs vest in a single installment on the earlier of the day before the next annual meeting or first anniversary of grant; all unvested RSUs vest upon change of control

No performance-conditioned director awards (e.g., PSUs) disclosed; RSUs are time-based .

Other Directorships & Interlocks

CompanyPublic/PrivateRolePotential Interlock/Conflict
Cobra Biologics Ltd.PrivateDirector (2020–2021)None disclosed with DTIL
Plume Design, Inc.PrivateChief Legal & Sustainability Officer; Chief Privacy OfficerNo disclosed commercial relationship with DTIL

No current public company directorships for Piré disclosed in the past five years .

Expertise & Qualifications

  • Legal, compliance, M&A execution (CDMO/cell and gene therapy transactions at Cognate; board service at Cobra Biologics) .
  • Privacy and cybersecurity governance (Chief Privacy Officer; privacy governance committee at Plume) .
  • Education: BA (UC Irvine), JD magna cum laude (NYLS), Editor of Law Review; admitted to NY and D.C. Bars .

Equity Ownership

CategorySharesNotes
Common shares (beneficially owned)4,202As of March 20, 2025
Options exercisable ≤60 days7,076As of March 20, 2025
Unvested RSUs (as of 12/31/2024)9,826Annual 2024 grant
Total beneficial ownership11,278<1% of outstanding shares
Shares pledgedNone disclosed
Hedging policyProhibits hedging and similar instruments by directors/officers/employees

Insider Trades (Form 4 Summary)

Filing DateTransaction DateDescriptionNotes/Link
May 7, 2024May 4, 2024RSU vesting and settlementAnnual director RSUs vesting event
June 6, 2024June 4, 2024Form 4 filedRSU-related reporting; standard director equity
June 4, 2025May 27, 2025RSU vestingAnnual RSU vesting reported

No open-market buys/sells by Piré disclosed; transactions reflect routine RSU settlement/vesting typical for DTIL non-employee director compensation .

Governance Assessment

  • Strengths
    • Independent director with legal, compliance, and transaction execution experience relevant to biotech/CDMO sectors .
    • Active governance roles: Chair of Nominating & Corporate Governance; member of Compensation; Board and committee attendance met thresholds; presence at annual meeting .
    • Anti-hedging policy in place; Board-level clawback policy for executives supports broader governance discipline .
  • Alignment and Incentives
    • Director pay structure mixes cash retainer plus equity RSUs; 2024 fees totaled $54,250 and annual RSUs valued at $129,998, aligning director compensation with shareholder outcomes via equity exposure .
    • Beneficial ownership is <1%; unvested RSUs and vested options increase exposure, but absolute shareholding remains modest for “skin in the game” analysis .
  • Conflicts/Red Flags
    • No related-party transactions involving Piré disclosed; no pledging or hedging permitted by policy .
    • Compensation consultant Aon also served as broker for D&O insurance (fees: $45,442 for comp consulting; $225,000 insurance brokerage), evaluated for conflicts by the committee, which found none—still a potential perception risk but mitigated by independence review and Board approval .
    • No public-company interlocks or supplier/customer ties disclosed for Piré; low attendance or pay anomalies not indicated .

Overall, Piré’s independence, committee leadership, and consistent attendance support board effectiveness; equity grants provide alignment, though direct share ownership is limited. Monitoring consultant relationships (Aon dual roles) and continued disclosure on director ownership guidelines would further enhance investor confidence .