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Lori Kunkel

Director at Enliven Therapeutics
Board

About Lori Kunkel

Lori Kunkel, M.D., age 67, is an independent Class III director at Enliven Therapeutics (ELVN) since April 2024; her current term runs through the 2026 annual meeting. She holds a B.A. from UC San Diego and an M.D. from the University of Southern California; she is board-certified in internal medicine and previously held certifications in hematology and oncology, bringing deep clinical and biotech board experience to ELVN’s board .

Past Roles

OrganizationRoleTenureCommittees/Impact
Loxo Oncology, Inc.Director; Acting Chief Medical OfficerDirector: 2014–2019; Acting CMO: 2013–2014Oversaw clinical strategy; oncology focus
Tocagen Inc.Director; Acting Chief Medical OfficerDirector: Sep 2015–Jun 2020; Acting CMO: Nov 2018–Apr 2019Clinical leadership; transition period
Curis, Inc.DirectorNov 2016–Sep 2022Board oversight at public biotech
Maverick Therapeutics, Inc.DirectorJan 2017–Apr 2021Private biotech governance

External Roles

OrganizationRoleTenurePublic/PrivateCommittees/Notes
Nurix Therapeutics, Inc.DirectorSince Aug 2019Private (per ELVN proxy)Not disclosed
ORIC Pharmaceuticals, Inc.DirectorSince Jun 2020PublicNot disclosed
K36 Therapeutics, Inc.DirectorSince Dec 2021PrivateNot disclosed
LAK505-CA, LLCPrincipal/OwnerSince Jun 2016Private consultancyBiotech consulting

Board Governance

  • Independence: ELVN’s board determined Dr. Kunkel is independent under Nasdaq rules; six of eight directors are independent .
  • Committee assignment: Member, Nominating & Corporate Governance Committee; chair is Andrew Phillips .
  • Attendance: In 2024, the board held 4 meetings; each director attended at least 75% of board and applicable committee meetings. The Nominating & Corporate Governance Committee held 3 meetings; Audit Committee held 4; Compensation Committee held 3 .
  • Class/term: Class III director; current term expires at the 2026 annual meeting .

Fixed Compensation

Component2024 Amount2025 Policy (if changed)Notes
Board annual cash retainer$35,000 $40,000 (effective Jan 2025) Paid quarterly, prorated
Nominating & Governance committee member fee$4,000 $5,000 (effective Jan 2025) Member fee; chair receives $8,000→$10,000
Total cash paid to Dr. Kunkel (2024)$33,379 Prorated due to April 2024 appointment
Director Compensation – 2024 ActualsCash Fees ($)Option Awards ($)Total ($)
Lori Kunkel, M.D.$33,379 $499,989 $533,368
  • Mix: Equity comprised ~94% of Dr. Kunkel’s 2024 director compensation (option grant value $499,989 vs. cash $33,379) .

Performance Compensation

Equity Award TypeGrant ValueVestingCaps/Notes
Initial Award (upon becoming director)$500,000 Value in 2024 36 equal monthly installments (time-based) Cap: ≤64,923 shares (subject to adjustments)
Annual Award (Q1 each year)$250,000 Value (raised to $325,000 in Jan 2025) Vests fully by next annual meeting or 1-year anniversary, whichever earlier Cap: ≤32,461 shares (chair higher cap; adjustments)
Change-in-Control (CIC)Full acceleration of outstanding director awards immediately prior to CIC (if serving through date) Single-trigger acceleration for directors
  • Performance metrics: None disclosed for director equity (time-based vesting only; no TSR/ESG metrics for directors) .

Other Directorships & Interlocks

Potential InterlockDetailsGovernance Consideration
ORIC PharmaceuticalsDr. Kunkel is a current ORIC director ; ELVN Chair Richard Heyman has served as an ORIC director and executive, including director since March 2015 Network ties may aid info flow; board should monitor for conflicts on overlapping industry matters

Expertise & Qualifications

  • Clinical and oncology expertise: Board-certified internist with prior hematology/oncology certifications; multiple acting CMO roles at oncology biotechs .
  • Biotech governance: Service on public and private biotech boards (ORIC, Loxo, Curis, Tocagen, Nurix, K36) evidences broad boardroom experience .

Equity Ownership

HolderShares Beneficially Owned% OutstandingBreakdown
Lori Kunkel, M.D.79,304 <1% (*) 45,926 shares held of record; 33,378 options exercisable within 60 days
Shares Outstanding (denominator)49,038,730
  • Hedging/pledging: ELVN prohibits hedging and pledging of company stock by directors and related persons, supporting alignment with shareholders .

Governance Assessment

  • Strengths: Independent status; strong clinical/oncology background; service on Nominating & Governance Committee; solid attendance norms; heavy equity-based pay encourages alignment; strict anti-hedging/pledging policy .
  • Compensation structure signals: 2025 increases to cash retainers and annual option award values (Initial $500k→$650k; Annual $250k→$325k), modestly raising guaranteed cash while maintaining equity-heavy mix for directors .
  • Conflicts/related-party: No related-party transactions disclosed involving Dr. Kunkel; board’s audit committee reviews and pre-approves related-party deals per policy .
  • Watch items / RED FLAGS:
    • Single-trigger acceleration of director equity upon change-in-control could be viewed as less shareholder-friendly in some governance frameworks; transparency mitigant exists via clear policy disclosure .
    • Historical option repricing at Former Enliven (Aug 9, 2022) lowered exercise prices to $2.48 for outstanding options; not tied to directors and predates Dr. Kunkel’s tenure, but remains a governance practice worth monitoring for future precedent .

Net: Dr. Kunkel’s independence, domain expertise, and equity-forward pay design support investor confidence; limited conflict exposure is positive. Continued monitoring of interlocks and CIC equity acceleration terms is advisable .