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Mika Derynck

Director at Enliven Therapeutics
Board

About Mika Derynck

Independent director (Class I) at Enliven Therapeutics since February 23, 2023; age 62; current term expires at the 2027 annual meeting . M.D. and B.A. in Biology from Boston University; Internal Medicine residency at Johns Hopkins Hospital; Medical Oncology fellowship at UCSF . Currently Executive Vice President and Oncology Therapeutic Area Head at Vir Biotechnology (since September 2024); prior senior roles at Amunix/Sanofi and Genentech . The board affirmatively determined she is independent under Nasdaq rules .

Past Roles

OrganizationRoleTenureCommittees/Impact
Genentech (Roche)Senior Group Medical DirectorJan 2004 – Apr 2019Oncology development leadership
Amunix PharmaceuticalsChief Medical OfficerApr 2019 – Feb 2022Company acquired by Sanofi; transitioned into Sanofi R&D
Sanofi (R&D)Global Head of Conditional Biologics (Amunix within Sanofi R&D)Feb 2022 – Sep 2024Led conditional biologics strategy

External Roles

OrganizationRoleTenureNotes
Vir Biotechnology, Inc.EVP & Oncology Therapeutic Area HeadSep 2024 – PresentEmployment role, not a disclosed directorship

Board Governance

  • Committees: Audit Committee member; Nominating & Corporate Governance Committee member .
  • Independence: Board determined Derynck and a majority of directors are independent; audit/compensation/NCG committees composed of independent directors as required .
  • Attendance: Board held 4 meetings in 2024; each director attended at least 75% of board and committee meetings; audit held 4, compensation 3, nominating 3 meetings .
  • Leadership/structure: Independent Chairman (Richard Heyman); CEO and Chair roles separated; independent director executive sessions occur regularly .
  • Stockholder support: 2025 Annual Meeting—Class II directors received strong support; auditor ratification received 45,392,647 “For” votes (no director election for Class I in 2025) .

Fixed Compensation

Component2024 Amount ($)Notes
Board annual cash retainer35,000Policy rate in 2024
Audit Committee member fee7,500Policy rate in 2024
Nominating & Corporate Governance Committee member fee4,000Policy rate in 2024
Cash fees earned (reported)46,500Derynck 2024 cash total aligns with committee memberships
Equity—Annual stock option award (grant-date fair value)249,890Reported option award value; time-based vesting
Total 2024 director compensation296,390Sum of cash and options reported for Derynck
  • Policy updates (effective Jan 2025): Board cash retainer increased to $40,000; committee chair/member fees increased; Annual option award “Value” increased to $325,000 (Chair $365,000) .

Performance Compensation

  • Structure: Non-employee director equity awards are stock options; Initial Awards vest monthly over 36 months; Annual Awards vest fully by the next annual meeting anniversary—time-based vesting without disclosed performance conditions .
  • Change-of-control treatment: Director equity awards (Initial and Annual) fully vest immediately prior to consummation of a change in control if service continues to that date .
Performance MetricApplies to Director Equity?Evidence
Revenue growthNo disclosed linkageDirector option awards are time-based per policy
EBITDA/Profit targetsNo disclosed linkageDirector option awards are time-based per policy
TSR percentile/market-basedNo disclosed linkageDirector option awards are time-based per policy
ESG goalsNo disclosed linkageNo ESG criteria disclosed for director awards

Other Directorships & Interlocks

  • Public company boards: None disclosed for Derynck in ELVN proxy biography .
  • Interlocks: Serves alongside OrbiMed partner Rishi Gupta (major ELVN holder) on ELVN’s board; board notes independence and related-party oversight via Audit Committee .

Expertise & Qualifications

  • Medical/oncology expertise with >20 years in biopharma; senior clinical and R&D leadership (Genentech, Amunix/Sanofi, Vir) .
  • Education: B.A. Biology; M.D.; Internal Medicine residency; Medical Oncology fellowship .
  • Governance: Independent director; Audit and NCG committee member; not designated audit committee financial expert (audit chair Jake Bauer is the financial expert) .

Equity Ownership

HolderBeneficial Ownership (shares)% Outstanding
Mika Derynck, M.D.102,587 (options exercisable within 60 days of 3/31/2025)<1% (*)

(*) “Represents beneficial ownership of less than one percent (1%)” per proxy table .

  • Hedging/pledging: Company Insider Trading Policy prohibits pledging and hedging by directors and related persons .

Governance Assessment

  • Alignment: Majority of director pay in equity options ($249,890 vs $46,500 cash in 2024), fostering alignment; time-based vesting and change-in-control acceleration typical for directors .
  • Independence & oversight: Derynck is independent; sits on Audit and NCG committees—the Audit Committee oversees related-party transactions; board regularly holds independent sessions; chair/CEO separation improves oversight .
  • Attendance/engagement: Board and committee meeting cadence with at least 75% attendance by all directors indicates engagement; audit met quarterly in 2024 .
  • Conflicts/related parties: No related-party transactions disclosed involving Derynck; Audit Committee reviews and pre-approves such transactions under a formal policy . Her employment at Vir Biotechnology is disclosed; no ELVN transactions with Vir disclosed .
  • Policies/Risk controls: Strict hedging/pledging prohibitions; compensation recovery policy applies to officers (not directors) for restatements . Stockholder support in 2025 suggests confidence in board oversight (auditor ratification overwhelming “For”) .
  • Red flags: None specific to Derynck disclosed (no pledging, no related-party transactions, independent status affirmed). Company-wide historical option repricing occurred in 2022 for certain options (not tied to Derynck’s director awards) .

Overall, Derynck brings deep oncology leadership and maintains independence, with meaningful equity-based pay and committee roles that support investor confidence; disclosed policies mitigate alignment risks, and no related-party or attendance concerns are noted .