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Lota S. Zoth

Director at enGene Holdings
Board

About Lota S. Zoth

Independent director since December 18, 2023; current term expires at the 2027 annual meeting. Zoth is a Certified Public Accountant, designated by the Board as an audit committee financial expert, and holds a B.B.A. from Texas Tech University. As of April 4, 2024, she was age 64; she brings senior finance leadership experience as former SVP & CFO of MedImmune and extensive public-company board audit leadership in life sciences .

Past Roles

OrganizationRoleTenureCommittees/Impact
MedImmune, Inc.Senior Vice President & Chief Financial OfficerApr 2004–Jul 2007Led finance at biotech; prior Controller/CAO
MedImmune, Inc.Vice President, Controller & Chief Accounting OfficerAug 2002–Apr 2004Financial reporting and internal control leadership

External Roles

OrganizationRoleTenureCommittees/Impact
89BIO, Inc. (Nasdaq: ETNB)DirectorJun 2020–Present
Inovio Pharmaceuticals, Inc. (Nasdaq: INO)Director; Audit Committee ChairDirector since Jan 2018; Audit Chair since Aug 2018Audit leadership
Lumos Pharma, Inc. (Nasdaq: LUMO)Director; Audit Committee ChairNov 2012–Dec 2024Audit leadership
Zymeworks Inc. (NYSE: ZYME)Director; Chair of Board; Lead DirectorDirector since Nov 2016; Chair Sep 2019–Jan 2022; Lead Director Jan 2022–Dec 2023Board leadership; stepped down Dec 2023
Spark Therapeutics, Inc.DirectorJan 2016–Dec 2019
Circassia Pharmaceuticals plc (LON: CIR)DirectorFeb 2015–Feb 2019
Orexigen Therapeutics, Inc.DirectorApr 2012–May 2019
Aeras (non-profit)DirectorNov 2011–Oct 2018
Hyperion Therapeutics, Inc.DirectorFeb 2008–May 2015
Ikaria, Inc.DirectorJan 2008–Feb 2014

Board Governance

  • Independence: The Board determined Zoth is independent under Nasdaq and NI 52-110; also meets heightened independence standards for audit committees under SEC/Nasdaq/NI 52-110 .
  • Committee roles: Audit Committee Chair; members include Zoth (Chair), Gerald Brunk, Richard Glickman; audit committee held five meetings in fiscal 2024; Zoth designated an “audit committee financial expert” . Nominating & Corporate Governance Committee member alongside Richard Glickman (Chair), Jasper Bos, Paul Hastings; committee held three meetings in fiscal 2024 . Not a member of the Compensation Committee; that committee comprises Gerald Brunk (Chair), Paul Hastings, Wouter Joustra; five meetings in fiscal 2024 .
  • Attendance: Board held eight meetings in fiscal 2024; no director attended fewer than 75% of the Board/committee meetings on which they served .
  • Board structure: Staggered board; Zoth’s term expires in 2027 . Independent directors hold regularly scheduled sessions without management .

Fixed Compensation

Compensation ElementFY 2023FY 2024
Fees earned or paid in cash (Zoth)$0 (Board paid no director compensation in FY2023) $54,327

Director fee schedule (policy applied in FY2024):

Compensation TypeAmount
Board—Independent Chair/Lead Independent Director annual cash fee$75,000
Board—All non-employee directors annual cash fee$40,000
Audit Committee—Chair$20,000
Audit Committee—Member$10,000
Compensation Committee—Chair$18,000
Compensation Committee—Member$9,000
Nominating & Corporate Governance—Chair$10,000
Nominating & Corporate Governance—Member$5,000

Policy caps: Non-employee director total annual compensation capped at $500,000; initial year cap $750,000 (cash plus equity grant date value) . Zoth’s FY2024 aggregate ($684,866) was within the $750,000 initial-year cap .

Performance Compensation

GrantGrant DateSharesVestingExpirationExercise PriceGrant-Date Fair Value (FY2024 total)
Initial Director Stock OptionMar 24, 202440,000One-third each on 1st, 2nd, 3rd anniversaries, subject to service 10 years FMV at grant Included in Zoth’s FY2024 option awards total $630,539
Annual Director Stock OptionJun 18, 202420,000100% on first anniversary, subject to service 10 years FMV at grant Included in Zoth’s FY2024 option awards total $630,539

Notes:

  • All non-employee director options expire 10 years from grant, have exercise price equal to the grant-date FMV, and are subject to continued Board service .
  • Zoth’s FY2024 total compensation: Option awards $630,539; cash fees $54,327; total $684,866 .

Other Directorships & Interlocks

DirectorOther Reporting IssuersExchanges
Lota ZothInovio Pharmaceuticals, Inc.; 89BIO, Inc.Nasdaq; Nasdaq
  • Related-party transaction screening: Disclosed related financings involve entities affiliated with other directors (Lumira; Forbion/FEAC), not Zoth. No material interests or related-party transactions were disclosed for Zoth in FY2024 .

Expertise & Qualifications

  • CPA; designated audit committee financial expert by the Board .
  • Senior finance leadership (MedImmune SVP & CFO; prior Controller/CAO) .
  • Deep audit and governance experience across multiple life science boards, including audit chair roles and board leadership (chair/lead director) .
  • B.B.A., Texas Tech University .

Equity Ownership

MetricOct 31, 2024Apr 25, 2025
Options outstanding (count)60,000; none vested as of Oct 31, 2024
Beneficial ownership (Rule 13d-3, shares)33,333; less than 1% (“*”) of 51,070,851 shares outstanding
Notes on beneficial ownershipIncludes 33,333 shares underlying stock options exercisable within 60 days (13,333 from initial option’s first tranche + 20,000 annual option)
  • Shares outstanding reference: 51,070,851 as of Apr 25, 2025 .
  • No pledging or hedging disclosures were identified in the proxy relating to Zoth; standard director indemnification agreements in place .

Governance Assessment

  • Strengths: Independent director with robust audit credentials; designated audit committee financial expert; chairs the Audit Committee; active committee participation (Audit; Nominating & Corporate Governance) and Board-level attendance compliance in FY2024 .
  • Alignment: Director pay structure emphasizes equity via options; Zoth’s initial-year equity awards and cash fees remain within the plan’s director cap, signaling discipline in director compensation governance .
  • Independence/Conflicts: No related-party transactions disclosed for Zoth; her other public company directorships (Inovio, 89BIO) are industry-adjacent but not disclosed as counterparties to enGene; audit committee policies include strict pre-approval and auditor independence oversight .
  • Committee effectiveness: Audit Committee met five times in FY2024; NCG met three times; independent directors hold regular executive sessions without management, supporting board oversight quality .
  • RED FLAGS to monitor:
    • Board diversity is limited (one woman out of seven, 14% as of 2025), which may draw investor scrutiny; the company has no formal diversity targets though NCG considers diversity in director recruitment .
    • No formal director term limits; relies on NCG evaluation and skills matrix for board renewal, which is acceptable but can be perceived as weaker than hard limits by some governance frameworks .