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Marella Thorell

Director at ESSA Pharma
Board

About Marella Thorell

Independent director since July 31, 2019; currently Audit Committee Chair and designated “audit committee financial expert” under SEC rules and financially literate under NI 52‑110 . Background includes >25 years in finance and operations with CFO roles at Seres Therapeutics (since Mar 2024) and prior senior finance roles at Evelo Biosciences, Centessa Pharmaceuticals, Palladio Biosciences, and Realm Therapeutics; started career at Ernst & Young and Campbell Soup; B.S. in Business, magna cum laude, Lehigh University . Board attendance in FY2024 was 100% for board (4/4) and audit committee meetings (4/4) . Beneficial ownership totals 91,881 shares including options exercisable within 60 days; ownership is below 1% of outstanding shares .

Past Roles

OrganizationRoleTenureCommittees/Impact
Realm Therapeutics plcCFO, COO, Executive DirectorDec 2016 – Jul 2019Led licensing and capital strategy; Realm acquired by ESSA in 2019
Palladio Biosciences Inc.Chief Financial OfficerOct 11, 2019 – Dec 2020CFO through acquisition by Centessa
Centessa Pharmaceuticals plcChief Accounting Officer; Head of FinanceJan 2021 – Apr 2021; Apr 2021 – Jul 2022Led public company readiness for IPO; oversaw finance ops
Evelo Biosciences, Inc.Chief Financial OfficerSep 2022 – Dec 2023Responsible for capital strategy and financial operations
Vallon PharmaceuticalsDirector; Board Chair; Audit Committee ChairFeb 2021 – Apr 2023 (Chair May 2022 – Apr 2023)Board leadership, audit oversight until merger with GRI Bio in Apr 2023
Campbell Soup CompanyFinance and operations rolesPrior (dates not specified)Progressive finance/operational roles
Ernst & Young LLPEarly career; earned CPAPrior (dates not specified)Public accounting foundation

External Roles

OrganizationRoleTenureCommittees/Impact
Seres Therapeutics, Inc.Chief Financial OfficerMar 2024 – PresentCFO of clinical-stage biotech focused on live biotherapeutics
Carisma Therapeutics, Inc.Director; Audit Committee ChairJun 2024 – PresentAudit leadership at immunotherapy company
Additional Interlock: Carisma TherapeuticsSanford Zweifach (EPIX director) is ChairmanNov 2021 – PresentShared external board exposure may influence information flow

Board Governance

  • Committee assignments: Audit Committee Chair; audit committee members are Marella Thorell (Chair), Gary Sollis, Sanford Zweifach, Franklin Berger; all independent under Nasdaq and Rule 10A‑3 and designated SEC “financial experts” .
  • Attendance FY2024: Board 4/4; Audit 4/4; not listed as member of compensation or governance committee in FY2024 .
  • Independence: Considered independent for audit committee per NI 52‑110, Nasdaq rules, Rule 10A‑3 .
  • Executive sessions: Independent directors meet in executive session at each regular board meeting; quarterly board cadence .
  • Tenure and diversity: Director since Jul 2019; female representation on board is 20% as of proxy date (Thorell and Merendino) .

Director Attendance (FY2024)

Meeting TypeAttendance
Board4 of 4
Audit Committee4 of 4

Fixed Compensation

  • Non-employee director cash fee schedule (annual): Board Member $40,000; Board Chair $70,000; Audit Committee Member $7,000; Audit Chair $18,500; Compensation Committee Member $6,000; Comp Chair $12,000; Governance Committee Member $4,000; Governance Chair $8,000 .
  • FY2024 actual paid to Thorell: Cash fees $50,250 .
MetricFY2024
Cash Fees ($)50,250
Option Awards (Grant-Date Fair Value, $)451,888
Total ($)502,138

Performance Compensation

  • Directors’ equity compensation: Stock options only; no RSUs/PSUs or non-equity incentives for directors currently .
  • Annual option grant practice: Initial board appointment grant vests monthly over 36 months; annual grant typically vests in full at the first AGM following grant date; in 2024, annual grant was 25,000 options, but 50,000 options were awarded to accommodate prior-year unawarded grants .
Equity Program FeatureDetail
Initial Option GrantVests ratably over 36 monthly installments
Annual Option GrantVests fully at first AGM post-grant; 2024 award level 25,000 (50,000 granted to address prior-year gap)
Director Share-Based AwardsNo RSUs/PSUs or deferred stock units at present (options only)

Other Directorships & Interlocks

CompanyRoleOverlap/Interlock
Carisma Therapeutics, Inc.Director; Audit ChairEPIX director Sanford Zweifach is Chairman at Carisma, creating cross-board network linkage
Vallon PharmaceuticalsDirector; Board Chair; Audit ChairRole ended Apr 2023 upon merger with GRI Bio, Inc.
Seres Therapeutics, Inc.CFOConcurrent external operating role as CFO since Mar 2024

Expertise & Qualifications

  • Financial expertise: Designated “audit committee financial expert”; extensive CFO/CAO background; SEC/Nasdaq audit independence and literacy confirmed .
  • Industry: Biopharma finance and operations, IPO readiness, capital strategy, licensing .
  • Education: B.S. in Business, Lehigh University, magna cum laude .

Equity Ownership

ItemAmountNotes
Beneficial Ownership (incl. options within 60 days)91,881 sharesAs of Jan 8, 2025 Record Date; percent marked “*” (<1%)
Common Shares (direct)2,881Footnote details
Options Exercisable within 60 Days89,000Footnote details
Total Options Held (as of Sep 30, 2024)139,000Director options outstanding
Shares Outstanding44,388,550As of Jan 8, 2025
Ownership % of Outstanding~0.21%Computed from 91,881 ÷ 44,388,550 using cited figures

Note: Vested vs. unvested approximate split inferred from 139,000 total options vs. 89,000 exercisable within 60 days of the Record Date, implying ~50,000 unexercisable at that time .

Governance Assessment

  • Strengths:

    • Audit Committee Chair with strong finance pedigree; committee independence and “financial expert” designation bolster reporting oversight .
    • Perfect FY2024 attendance on board and audit committee, signaling active engagement .
    • Clear director cash and equity framework; annual options vesting aligned to AGM timing; no RSUs/PSUs for directors reduces complexity and potential pay-for-performance misalignment at the board level .
    • Executive sessions of independent directors at each regular board meeting support independent oversight .
  • Watch items / potential conflicts:

    • Cross-board interlock at Carisma Therapeutics with fellow EPIX director (Zweifach as Chairman) introduces network linkages; monitor for any related-party considerations if commercial ties emerge between entities (none disclosed) .
    • External full-time CFO role at Seres Therapeutics (from Mar 2024) raises time-allocation considerations; EPIX overboarding policy allows up to five public boards, but operating roles are separate; attendance suggests current engagement is adequate .
    • Section 16(a) late filing: one Form 4 for an option acquisition was filed late by Thorell in FY2023—administrative red flag; monitor for recurrence .
  • Policies and controls:

    • No term limits; board composition assessed on performance and skills mix; gender diversity policy without specific quotas; current female board representation 20% .
    • BCBCA conflict rules require disclosure and recusal on material contracts; board practice to abstain from discussions/votes when disclosable interests exist .

Director Compensation Structure (Reference)

ComponentAmount ($)
Board Member Annual Retainer40,000
Board Chair Annual Retainer70,000
Audit Committee Member7,000
Audit Committee Chair18,500
Compensation Committee Member6,000
Compensation Committee Chair12,000
Governance & Nomination Member4,000
Governance & Nomination Chair8,000

Insider Trades and Filings

ItemDetail
Section 16(a) compliance (FY2023)One Form 4 for an option acquisition was filed late by Marella Thorell (and similar isolated late filings by several EPIX insiders)

No additional insider trading details were disclosed in the proxy; continue monitoring Form 4 filings for timeliness and potential hedging/pledging disclosures (none noted).

RED FLAGS

  • Late Section 16(a) Form 4 filing (administrative oversight) .
  • Cross-board interlock (Carisma Therapeutics) with another EPIX director—monitor for any related-party transactions; none disclosed .

Notes

  • Say‑on‑pay data, director stock ownership guidelines, pledging/hedging policies, and use of independent compensation consultants are not specifically disclosed for directors; skip per instruction.
  • No related-party transactions involving Thorell are disclosed in the proxy; BCBCA rules enforce disclosure/recusal in such events .