Sanford Zweifach
About Sanford Zweifach
Sanford Zweifach has served as an independent director of ESSA Pharma Inc. since July 31, 2019, with a 30-year biotechnology career spanning operating and investment roles. He holds a B.A. in Biology from UC San Diego and an M.S. in Human Physiology from UC Davis, and currently serves in multiple external leadership positions in biopharma companies .
Past Roles
| Organization | Role | Tenure | Committees/Impact |
|---|---|---|---|
| Nuvelution Pharma Inc. | Chief Executive Officer | Nov 2015 – Dec 2020 | Co-founder; operating leadership |
| Nuvelution Pharma Inc. | Co-Founder and Senior Advisor | Jun 2015 – Dec 2020 | Strategic advisory |
| Palladio Biosciences | Chairman of the Board | Apr 2019 – Feb 2021 | Board leadership |
| IMIDomics SL | Acting President and Chief Business Officer | Dec 2019 – Present | Executive leadership |
| Janpix Inc. | Executive Chairman | Dec 12, 2019 – Present | Company oversight |
| Bay City Capital | Managing Director and CFO | Not disclosed | Investment/finance leadership |
| Epoch Biosciences (acquired by Nanogen) | President and CFO | Not disclosed | Operating leadership |
| Ascendancy Healthcare, Inc. | Co-founder and CEO | Not disclosed | Company formation and leadership |
| Pathways Diagnostics | CEO | Not disclosed | Operating leadership |
| Reedland Capital Partners | Partner | Not disclosed | Investment role |
External Roles
| Organization | Role | Tenure | Exchange/Listing |
|---|---|---|---|
| Compugen Ltd. | Non-Executive Board Member (Director) | Jun 2018 – Present | Nasdaq |
| Carisma Therapeutics Inc. | Chair of the Board | Nov 2021 – Present | Nasdaq |
| Kaerus Biosciences Ltd. | Executive Chair | Not disclosed | Private |
| IMIDomics SL | Acting President and CBO | Dec 2019 – Present | Private |
Board Governance
- Independence: Zweifach is an independent director under Canadian securities laws and Nasdaq rules .
- Committee work: He served on the Audit Committee in 2023–2024 alongside Franklin Berger (Chair), Gary Sollis, and Marella Thorell, providing oversight of financial reporting and auditor independence .
- Current committee leadership (board-wide): Audit Committee chair is Marella Thorell; Compensation Committee chair is Scott Requadt; Corporate Governance & Nomination Committee (CGNC) chair is Gary Sollis (members include Lauren Merendino, Franklin Berger, and Richard Glickman) .
- Shareholder voting signal: At the March 5, 2025 AGM, Zweifach received 9,112,900 “For” votes (98.63%) with 126,371 “Withheld” (1.37%), indicating strong investor support .
- Governance policies: ESSA maintains a majority voting policy requiring directors failing to secure a majority of votes cast to tender their resignation, and an advance notice policy for director nominations .
- Risk oversight: The Board and committees (notably Audit) oversee risk, with independent directors holding regular in-camera sessions; the Board meets at least quarterly .
- Attendance: Individual director meeting attendance rates are not disclosed in the cited materials .
Fixed Compensation
- Board cash fee structure (annual retainers)
| Component | FY 2024 Schedule (per 2024 proxy) | FY 2025 Schedule (per 2025 proxy) |
|---|---|---|
| Board Member | $35,000 | $40,000 |
| Board Chair | $60,000 | $70,000 |
| Audit Committee – Member | $7,000 | $7,000 |
| Audit Committee – Chair | $15,000 | $18,500 |
| Compensation Committee – Member | $6,000 | $6,000 |
| Compensation Committee – Chair | $12,000 | $12,000 |
| Corporate Governance & Nomination – Member | $4,000 | $4,000 |
| Corporate Governance & Nomination – Chair | $8,000 | $8,000 |
- Director cash actually paid (FY 2024)
| Director | Fees Earned or Paid in Cash ($) | Option Awards ($, grant-date FV) | Total ($) |
|---|---|---|---|
| Sanford Zweifach | $50,500 | $451,888 | $502,388 |
- Cost structure signal: The company disclosed base increases for Board remuneration effective April 2024 and a higher number of directors compared to the prior period, contributing to increased director fees .
Performance Compensation
- Equity framework for non-employee directors:
| Item | Detail |
|---|---|
| Initial option grant (upon appointment) | 50,000 options vest ratably over 36 monthly installments; no initial grants in 2024 |
| Annual option grant | Typically granted on/around AGM; 2024 annual grant was 25,000 options, with 50,000 awarded to members to accommodate prior-year unawarded grants; annual awards vest in full at the first AGM following grant |
| Option holdings (as of 9/30/2024) | Zweifach held 139,000 options to purchase common shares |
| Performance linkage | Director equity awards are time-based options; no disclosed performance metrics tied to director compensation; hedging/speculation in company securities is prohibited |
Other Directorships & Interlocks
| Person | Company | Role | Potential Interlock/Notes |
|---|---|---|---|
| Sanford Zweifach | Compugen Ltd. | Director | External public board; biotech sector |
| Sanford Zweifach | Carisma Therapeutics Inc. | Chair | External public board; biotech sector |
| Marella Thorell (EPIX director) | Carisma Therapeutics Inc. | Director & Audit Committee Chair | Shared external board with Zweifach; potential information flow interlock (not a related-party transaction by itself) |
Expertise & Qualifications
- Qualifications: Operating executive and investor across biotech companies, including CEO, CFO, Chairman/Executive Chair roles; recognized by the Board for compensation committee-relevant expertise serving on compensation committees of other public companies .
- Education: B.A. Biology (UC San Diego); M.S. Human Physiology (UC Davis) .
Equity Ownership
| Holder | Beneficially Owned Common Shares | % of Shares Outstanding | Options Held (as of 9/30/2024) |
|---|---|---|---|
| Sanford Zweifach | 89,000 | * (less than 1%) | 139,000 |
Note: As of record date January 8, 2025, 44,388,550 shares were outstanding; option shares exercisable within 60 days are included for the holder’s percentage calculation but not for others, per SEC rules .
Governance Assessment
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Strengths
- Independence and committee service: Zweifach is independent and has served on the Audit Committee, supporting financial reporting oversight and auditor independence .
- Shareholder support: 98.63% “For” votes at the March 2025 AGM suggest strong investor confidence in his continued board service .
- Ownership alignment: Meaningful equity via options (139,000 held as of 9/30/2024) and personal share ownership (89,000 common shares) aligns incentives with shareholders .
- Governance policies: Majority voting and advance notice policies improve accountability and nomination transparency; anti-hedging policy reduces misalignment risks .
-
Watch items
- Multi-board load: Concurrent leadership roles at Carisma and other entities may pose time-allocation risks; monitor engagement and attendance disclosures as available .
- Interlocks: Shared Carisma board service with EPIX director Marella Thorell merits routine monitoring for conflicts; ESSA’s Related Person Transactions Policy requires disinterested CGNC approval and annual disclosures, and recent filings report no related-party contracts beyond disclosed policy-compliant matters .
- Pay dynamics: Board fee base increases effective April 2024 increased director fee expense; continue to assess cash vs equity mix and overall cost vs outcomes as ESSA’s corporate direction evolves post-program termination .
-
Red Flags observed: None material disclosed — filings indicate no director penalties/sanctions, no individual bankruptcies, and no related-party transactions requiring disclosure beyond ordinary-course items; hedging is prohibited .
Appendix: Shareholder Vote Signals (2025 AGM)
| Proposal | For | Against/Withheld | Broker Non-Votes |
|---|---|---|---|
| Set number of directors | 18,276,662 | 596,630 | 2 |
| Election — Sanford Zweifach | 9,112,900 (98.63%) | 126,371 (1.37%) | 9,646,523 |
| Auditors appointment/remuneration | 18,821,777 (For) | 51,517 (Withheld) | 0 |
| Say-on-Pay (advisory) | 6,665,705 (For) | 2,561,065 (Against) | 9,646,524 |