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Daniel M. Bradbury

Chairman of the Board at EquilliumEquillium
Board

About Daniel M. Bradbury

Daniel M. Bradbury, 63, is Executive Chairman of Equillium and has served on the Board since March 2017; he previously served as CEO (June 2018–December 2019) and President (March 2017–June 2018), and co-founded Equillium . He holds a Bachelor of Pharmacy from Nottingham University and a Diploma in Management Studies from Harrow and Ealing Colleges of Higher Education (UK) . He is not independent due to his current employment, and he chairs the Board; the Board has no lead independent director .

Past Roles

OrganizationRoleTenureCommittees/Impact
Equillium, Inc.Executive ChairmanJan 2020–present Board Chair; facilitates information flow between Board and management
Equillium, Inc.Chief Executive OfficerJun 2018–Dec 2019 Led company operations
Equillium, Inc.PresidentMar 2017–Jun 2018 Co-founder; early-stage leadership
Amylin Pharmaceuticals, Inc.President, CEO, DirectorMar 2007–Aug 2012 Led public biopharma until acquisition by BMS
BioBrit, LLCFounder & Managing MemberSep 2012–present Life-science consulting/investment firm

External Roles

OrganizationRoleTenureCommittee Roles
Castle Biosciences, Inc.Director; Chairman of the BoardJul 2019–present Compensation Committee member
Biocon Biologics Ltd.DirectorJan 2019–present Audit Committee member
Vivani Medical, Inc.DirectorMar 2024–present Audit Committee member
Prior: Intercept Pharmaceuticals, Inc.Director2016–2023
Prior: Biocon Ltd.Director2013–2022
Prior: Corcept Therapeutics Inc.Director2012–2019
Prior: Geron CorporationDirector2012–2019
Prior: Illumina, Inc.Director2004–2017
Prior: Panacea Acquisition Corp.Director2020–2021

Board Governance

  • Independence: Not independent due to current employment; Board majority is independent (Demski, Manian, McDermott, Pruzanski, Troupin), but Bradbury, Connelly, Steel are not; Colabuono preliminarily not independent due to Decheng affiliation .
  • Board leadership: Chaired by Executive Chairman Bradbury; no lead independent director .
  • Committees: Bradbury serves on none; Board committees are Audit, Compensation, and Nominating & Corporate Governance .
  • Meetings/attendance: Board met six times and acted by unanimous written consent three times in 2024; all directors attended at least 75% of the aggregate Board and committee meetings on which they served .
  • Executive sessions: Independent directors hold regular executive sessions at Board and committee meetings .

Fixed Compensation

YearRoleCash (Salary/Fees, $)Notes
2024Executive Chairman164,000 Bradbury is compensated as an employee; does not receive non-employee director policy compensation
  • Non-employee director compensation policy (context for the Board): annual cash retainer $42,000; chair of Board additional $20,000; committee member retainers $10,000 (Audit), $7,500 (Comp), $5,000 (Nominating), and chair retainers $20,000 (Audit), $15,000 (Comp), $10,000 (Nominating); initial option 40,000 shares vesting over 3 years; annual option 20,000 shares vesting over 1 year; full vesting on change-in-control; 10-year term; post-termination exercise period 12 months (non-cause) . Bradbury does not participate in this policy .

Performance Compensation

Grant DateInstrumentQuantity (shares)Exercise Price ($/sh)VestingGrant Date Fair Value ($)
Jan 2, 2024Stock Option50,000 0.7343 25% on 1st anniversary; balance in ~equal monthly installments over next 36 months 25,982 (2024 option awards table)
  • As of Dec 31, 2024, Bradbury had 328,708 shares subject to outstanding options .
  • Company compensation practices: clawback policy maintained; bonuses dependent on corporate objectives; no excise tax/gross-up; no single-trigger change-in-control benefits; no hedging or pledging; no guaranteed bonuses/base increases .
  • Plan administration red flag: the Amended 2018 Equity Incentive Plan allows option/SAR repricing or substitution without stockholder approval (with participant consent), which can be shareholder-unfriendly if misused .

Other Directorships & Interlocks

CompanyRelationship to EQ/BoardInterlock/Conflict Notes
Decheng-affiliated Ariagen transactionEQ acquired Ariagen; >92% owned by Decheng; potential milestones up to $55.0M (≈$50.6M to Decheng affiliates); board member Colabuono is Decheng managing director; former director Xu is Decheng partner Board-level related-party exposure; Colabuono preliminarily not independent; oversight via related-person policy and Audit Committee
Bradbury’s external boards (Castle, Vivani, Biocon Biologics)No EQ-related transactions disclosedNo direct related-party transactions disclosed involving Bradbury

Expertise & Qualifications

  • Former CEO and founder roles at EQ; prior CEO of Amylin; extensive executive and board experience across biopharma and diagnostics .
  • Committee expertise externally: compensation (Castle) and audit (Biocon Biologics, Vivani) .
  • Education: Pharmacy degree and management studies credentials .

Equity Ownership

Holder/VehicleShares (#)Notes
Total beneficial ownership (Bradbury)3,978,618 11.1% of outstanding shares (35,719,317 as of Apr 1, 2025)
BioBrit LLC1,838,688 Bradbury is managing member
Bradbury Family 2009 Irrevocable Trust742,399
Annette E. & Daniel M. Bradbury Irrevocable Descendant’s Trust (Annette trustee)565,454
Annette E. & Daniel M. Bradbury Irrevocable Descendant’s Trust (Daniel trustee)565,454
Options exercisable within 60 days (included in beneficial)266,623 Included per SEC rules
  • Company policy prohibits hedging or pledging of company stock (alignment positive) .
  • No disclosure of shares pledged as collateral for Bradbury .

Governance Assessment

  • Strengths:

    • Deep operating and board experience; external committee expertise in audit and compensation supports governance quality .
    • High ownership (11.1%) aligns interests with shareholders; hedging/pledging prohibited; clawback policy in place .
    • Regular independent executive sessions and majority-independent Board .
  • Concerns / RED FLAGS:

    • Not independent and serves as Board Chair; absence of a lead independent director reduces independent oversight of management .
    • Plan permits option/SAR repricing without shareholder approval, a potential shareholder-unfriendly practice if exercised imprudently .
    • Board-level related-party exposure via Decheng (Ariagen acquisition), with a current director affiliated; requires vigilant Audit Committee oversight and recusals .
  • Engagement & Attendance: Board met 6 times; all directors ≥75% attendance—no attendance red flags disclosed for Bradbury .

  • Compensation Alignment:

    • Modest Executive Chairman salary ($164k) plus time-based options; no 2024 bonus disclosed for Bradbury; options vest over 4 years, supporting long-term orientation .
    • Bradbury does not participate in non-employee director compensation policy, avoiding double-dipping .

Overall, Bradbury brings substantial sector leadership and aligned ownership but his non-independent Board chair role and plan repricing flexibility warrant attention; independent director leadership and continued rigorous related-party oversight would bolster investor confidence .