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Julie Hambleton

Director at Erasca
Board

About Julie Hambleton

Julie Hambleton, M.D., age 67, is an independent Class II director of Erasca, Inc., serving since March 2021; her current term runs to the 2026 annual meeting. She is a hematologist-oncologist and biopharma executive who previously served as SVP/Chief Medical Officer/Head of Development at IDEAYA, VP Head US Medical at Bristol-Myers Squibb, EVP/CMO at Five Prime Therapeutics, VP Clinical Development at Clovis Oncology, and held senior BioOncology roles at Genentech; she trained in heme/onc at UCSF (faculty 1993–2003), holds a B.S. in Nursing (Duke) and M.D. (Case Western), and was board-certified in hematology and internal medicine .

Past Roles

OrganizationRoleTenureCommittees/Impact
IDEAYA BiosciencesSVP, Chief Medical Officer, Head of DevelopmentJun 2018 – Apr 2020 (retired)Led development in oncology medicines
Arch Therapeutics (private)Interim President & CEOAug 2020 – Mar 2021Interim leadership during transition
Bristol-Myers SquibbVice President, Head US MedicalMay 2016 – Sep 2017US medical leadership
Five Prime TherapeuticsEVP & Chief Medical Officer; earlier SVP & CMOAug 2015 – Feb 2016; Dec 2012 – Aug 2015Clinical leadership
Clovis OncologyVice President, Clinical DevelopmentApr 2010 – Nov 2012Clinical development
GenentechRoles of increasing responsibility, BioOncology2003 – 2010Oncology development
UCSFHematology-Oncology training; FacultyTraining; Faculty 1993 – 2003Academic/clinical practice

External Roles

CompanyRolePublic/PrivateStart
IGM Biosciences, Inc.DirectorPublicAug 2018
SpringWorks Therapeutics, Inc.DirectorPublicMay 2020

Board Governance

  • Independence: The Board has determined Dr. Hambleton is independent under Nasdaq listing rules; she is listed as an independent Class II director (term expiring 2026) .
  • Committee assignments (2024/2025): Audit Committee (member); Compensation Committee (member). Audit Committee chaired by Alexander W. Casdin; Compensation Committee chaired by James A. Bristol .
  • Meeting cadence: Board met six times in 2024; each director attended at least 75% of Board and relevant committee meetings. Audit met 4x; Compensation met 5x; Nominating & Corporate Governance met 2x .
  • Responsibilities touchpoints: Audit oversees financial reporting, related-party review, and cybersecurity risk; Compensation oversees executive and director pay and uses independent consultant Alpine Rewards (no conflicts) .
  • Governance policies: Prohibits pledging/hedging, margin, short sales, and derivatives on company stock; Code of Ethics and Insider Trading Policy apply to directors .
  • Board structure context: Classified (staggered) board; directors removable only for cause with supermajority—a potential entrenchment factor at the board level (not director-specific) .

Fixed Compensation

Component (Non-Employee Director)Amount (USD)Notes
Annual Board retainer (2024)$40,000Standard cash retainer
Audit Committee member retainer (2024)$7,500Member retainer
Compensation Committee member retainer (2024)$5,000Member retainer
Total fees earned/paid in cash (2024)$52,500As reported for Dr. Hambleton
  • Program updates effective 2025: Compensation Committee chair/member retainers increased to $12,000/$6,000; Nominating & Corporate Governance chair/member to $10,000/$5,000 .

Performance Compensation

Equity/Policy ItemDetail
Option awards (grant-date fair value, 2024)$85,866 for Dr. Hambleton
Options outstanding (12/31/2024)326,666 options
Annual director equity (2024 program)Options to purchase 60,000 shares; vest at next AGM or 1-year anniversary
Initial director equity (pre-2025)Options to purchase 120,000 shares; vest over three years
Program update (2025+)Annual option grant increased to 120,000; initial grant increased to 240,000
Retainer-in-options electionDirectors may elect to receive cash retainers as options; footnotes list incremental values for certain directors (Dr. Hambleton is not listed among those electing in 2024)
ClawbackCompany adopted a compensation recovery policy for certain erroneously paid incentive compensation to Section 16 officers on/after Oct 2, 2023, per SEC/Nasdaq rules

Other Directorships & Interlocks

  • Current public boards: IGM Biosciences (since Aug 2018); SpringWorks Therapeutics (since May 2020) .
  • Compensation Committee interlocks: None—no executive officer interlocks and no committee member has served as an Erasca officer .

Expertise & Qualifications

  • Medical and development leadership in oncology across Genentech, Clovis, Five Prime, BMS, and IDEAYA, with prior academic heme/onc practice at UCSF—strong fit for Erasca’s oncology focus .
  • Education: B.S. Nursing (Duke), M.D. (Case Western), board-certified in hematology and internal medicine .

Equity Ownership

MetricValue
Beneficial ownership (shares)272,666 shares (as of April 15, 2025)
Ownership % of outstandingLess than 1% of 283,265,716 shares outstanding
Options outstanding (12/31/2024)326,666 options
Methodology noteBeneficial ownership includes securities exercisable within 60 days per SEC rules
Hedging/pledgingProhibited for directors under company policy

Governance Assessment

  • Strengths: Independent director with deep oncology development expertise; active on Audit and Compensation Committees; board-level policies prohibit pledging/hedging; use of independent comp consultant (no conflicts); attendance at or above minimum threshold (≥75% in 2024) .
  • Alignment: Director pay combines cash retainers with meaningful option grants; program allows optional retainer-in-options and increased annual grants from 2025, potentially enhancing equity alignment. Dr. Hambleton received $52,500 in cash fees and $85,866 in option value in 2024; she is not listed among those who elected retainer-in-options in 2024 .
  • Conflicts/related-party exposure: Audit Committee reviews related-party transactions; proxy discloses certain relationships (e.g., Erasca Foundation, legacy shareholder agreements) but none attributed to Dr. Hambleton; Compensation Committee interlocks explicitly “none” .
  • Risk flags: None specific to Dr. Hambleton identified (no attendance shortfall, no related-party ties, no pledging). Board-level entrenchment features exist (classified board, removal for cause with supermajority) but are structural rather than director-specific. RED FLAG (board-level): staggered board with for-cause removal only may reduce accountability in contested scenarios .