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Jay Shepard

Director at Esperion TherapeuticsEsperion Therapeutics
Board

About Jay P. Shepard

Independent director at Esperion Therapeutics appointed in May 2018; age 67. Shepard is an advisor at Catalys Pacific and the former President & CEO of Aravive (Versartis), with 35+ years of biopharma commercialization experience and participation in 16+ product launches. He holds a B.S. in Business Administration from the University of Arizona. He currently serves on the board of Inovio Pharmaceuticals; additional roles include boards of Cessation Therapeutics and Aculys Pharma (private), observer at Pathalys Pharma, and board member of the Christopher & Dana Reeve Foundation . The Board has determined he is independent under NASDAQ rules .

Past Roles

OrganizationRoleTenureCommittees/Impact
Aravive Inc. (formerly Versartis, Inc.)President & CEOMay 2015 – Jan 2020Led commercialization planning; retired 2020
Versartis, Inc.Executive Chairman2013 – 2015Governance and strategy oversight
Sofinnova VenturesExecutive Partner2008 – 2015Portfolio company support; deal leadership
NextWave Pharmaceuticals (acquired by Pfizer)President & CEO; Board member2010 – 2012Exit to Pfizer; speciality pharma focus
Relypsa (Ilypsa spin-out; acquired by Galenica)Interim President & CEO2005 – 2007Early-stage leadership
TelikVP, Commercial OperationsPrior roleCommercial leadership
Alza (acquired by Johnson & Johnson)Oncology Business Unit HeadPrior roleUnit P&L leadership

External Roles

OrganizationRolePublic/PrivateTenureCommittees/Notes
Inovio Pharmaceuticals (NASDAQ: INO)DirectorPublicCurrentBoard service; noted as current in 2025 proxy . (2024 proxy also noted vice-chair and committee memberships)
Cessation Therapeutics, Inc.DirectorPrivateCurrentBoard service
Aculys Pharma, Inc.DirectorPrivateCurrentBoard service
Pathalys Pharma, Inc.ObserverPrivateCurrentBoard observer
Christopher & Dana Reeve FoundationDirectorNon-profitCurrentBoard service
Ironwood Pharmaceuticals (prior)DirectorPublicPrior to 2025Listed in 2024 proxy; not listed as current in 2025 proxy

Board Governance

  • Independence: Board has determined all directors other than the CEO are independent; Shepard is independent .
  • Committee assignments:
    • Chair, Nominating & Corporate Governance Committee .
    • Member, Audit Committee (not designated audit financial expert) .
  • Attendance and engagement:
    • In 2024, the Board held 11 meetings; Audit (4), Compensation (5 + 3 written consents), Nominating & Governance (2 + 1 written consent), Compliance (4). Each incumbent director attended at least 75% of applicable meetings .
    • Board regularly holds executive sessions of independent directors .
  • Committee leadership transition: Following the 2025 Annual Meeting, Audit Committee chair to transition from Alan Fuhrman to Robert E. Hoffman; Shepard remains a member .

Fixed Compensation (Director)

ComponentAmount (USD)Notes
Annual Board Cash Retainer$50,000Non-employee directors
Nominating & Governance Committee Chair Retainer$10,000Chair role
Audit Committee Member Retainer$10,000Non-chair member
Total Annual Cash (Illustrative for Shepard’s roles)$70,000Matches 2024 director fees paid

Performance Compensation (Director Equity)

ItemDetail
Annual equity structure (effective May 23, 2024)Choice of (a) 32,500 stock options + 23,000 RSUs, or (b) 65,000 options
Vesting for annual director awardsVest on earlier of one-year anniversary or next Annual Meeting; RSUs accelerate upon death/disability/change in control
Per-director annual capAll cash + equity grant-date fair value capped at $750,000/year
2024 Awards to Shepard (grant-date fair values)RSUs: $51,750; Options: $53,082; Total: $104,832

Other Directorships & Interlocks

CompanyRelationship to ESPRInterlock/Conflict Risk
Inovio Pharmaceuticals (current)Unrelated therapeutic focusNo ESPR-disclosed conflicts or related-party dealings
Ironwood Pharmaceuticals (prior)Unrelated to ESPR’s LDL-C franchisePrior service only per 2024 proxy; no conflict disclosed
  • Related-party transactions: The proxy discloses review procedures and, aside from standard compensation, no related-party transactions involving directors were disclosed for the period since Jan 1, 2024 .

Expertise & Qualifications

  • Commercialization leader (16+ launches) across pharma/biotech/drug delivery; deep commercial operations experience .
  • Governance leadership as committee chair for Nominating & Corporate Governance; service on Audit Committee .
  • Education: B.S., Business Administration, University of Arizona .

Equity Ownership

HolderTotal Beneficial Ownership (shares)% OutstandingBreakdown
Jay P. Shepard143,799<1%28,599 shares held; 92,200 options exercisable within 60 days; 23,000 RSUs vesting within 60 days (as of April 1, 2025; 198,149,421 shares outstanding)
  • Pledging/Hedging: Insider trading policy prohibits short sales/derivatives and prohibits margin/pledging absent Audit Committee approval; no pledges disclosed for Shepard .
  • Ownership alignment: Annual RSU/option awards and fixed cash/equity policy provide ongoing equity exposure .

Governance Assessment

  • Positives:
    • Independent director with extensive commercial track record; chairs Nominating & Governance (positive for board refreshment/succession) and serves on Audit (risk oversight support) .
    • Attendance threshold met; regular independent executive sessions enhance oversight .
    • Clawback policy adopted Nov 8, 2023; hedging/pledging restrictions in place; no related-party transactions disclosed involving Shepard .
  • Watch items:
    • Equity plan share increases (6.25M additional shares proposed for 2025) can raise dilution concerns; however, plan has no “liberal” CIC provisions and director pay is capped at $750k/year .
    • 2024 Say-on-Pay support was ~74%, indicating room for continued investor engagement on pay practices .
  • Shareholder voting:
    • 2024 say-on-pay: ~74% approval; Compensation Committee maintained overall approach while committing to ongoing monitoring .
    • 2025 voting results will be reported via 8-K after the Annual Meeting (May 29, 2025) .

Director Compensation (2024 Actual)

DirectorFees Earned (Cash)RSU Grant-Date ValueOption Grant-Date ValueTotal
Jay P. Shepard$70,000$51,750$53,082$174,832

Board & Committee Activity (2024)

BodyMeetings/Actions
Board of Directors11 meetings; 3 unanimous written consents
Audit Committee4 meetings
Compensation Committee5 meetings; 3 unanimous written consents
Nominating & Corporate Governance Committee2 meetings; 1 unanimous written consent
Compliance Committee4 meetings

Policy & Plan Highlights (relevant to directors)

  • Director compensation structure: cash retainers + annual equity choice; RSUs/options vest at next annual meeting; RSUs accelerate upon death/disability/CIC .
  • Equity plan governance: fixed-share plan (no evergreen), no option repricing without shareholder approval, minimum one-year vesting (limited exceptions), no single-trigger “liberal” CIC .
  • Clawback: RECOVER incentive-based comp upon material restatement (3-year lookback) .
  • Insider trading: Prohibitions on hedging, short sales, derivatives; restrictions on margin/pledging without approval .

No legal proceedings involving Shepard are disclosed; the company states no directors/officers have been subject to specified legal proceedings over the prior decade .