Evotec - Q3 2023

Transcript

Operator (participant)

Ladies and gentlemen, thank you for standing by. Welcome and thank you for joining the Evotec SE quarterly statement, nine months, 2023. Throughout today's recorded presentation, all participants will be in a listen-only mode. The presentation will be followed by a question and answer session. If you would like to ask a question, you may press star followed by one on your touchtone telephone. Please press the star key followed by zero for operator assistance. I would now like to turn the conference over to Dr. Werner Lanthaler, CEO. Please go ahead.

Werner Lanthaler (CEO)

Thank you. Good morning. Good afternoon. Welcome to our Q3 call. Resilient into the Future of Biopharma R&D. That's how we titled this presentation, which we have uploaded to the internet, and you are welcome to join this call also with the presentation. Resilience is all about being able to overcome the unexpected. Our goal of resilience is to follow science and technology and thrive together with our partners. So you will see throughout this presentation that resilience is not what happens to you. Resilience for us is how you react to something, how you respond to something, and how you recover from what happens to you.

I'm here together with my team, which you see on slide number three of this presentation, with Laetitia, with Matthias, with Craig, and with Cord, and I want to thank them very much for driving resilience into our company stronger than ever before. If you go to page number five of your presentation, you see the highlights, and I want to stress it's basically only highlights on our Q3. If we reflect a little bit on this year, you see that we are going strong again with a cyber attack in the rear mirror now. When I say we go strong again, reporting double-digit growth of 14% on top line and 13% on bottom line, despite the cyber attack, is a great result. More importantly, we are driving this company into the long-term future, and here are just a few events that highlight that.

For example, a major collaboration in neurodegeneration together with BMS was started in 2023. For example, the continued validation of our Just Evotec Biologics business, where we, where we have an excellent pipeline building moment that we witness all together here. The tech alliance with Sanofi, also an agreement with the Department of Defense, highlight this and make our second trade port that we are building in Toulouse an absolutely vital investment into the future. We are building pipelines together with our partners. That's the measurements that you should take in looking at value increase of Evotec into the future. So strong progress in our pipeline building efforts is highlighting value creation into the future. Here, we'll then talk a bit in the later part of this presentation about multiple events that are happening that are driving this value forward.

What you should also appreciate is that we are following science, and not only by, for example, translating science with Novo Nordisk or out of Singapore via our bridges, we can highlight this commitment. Of course, we are more than ever and fully committed to our ESG topics, which are highlighted here on our SBTi targets. Yes, there is a lot happening in the company, and of course, we are also aware that this is happening in light of not so easy biotech times out there, because after COVID times, there was of course a bit of a market volatility where we think that our business model shows that we are clearly differentiated with our technology stack to many other companies who can only react to that crisis. We are creating opportunities out of this crisis.

So I want to stress again that we really see our business model of Evotec more as the answer to the biotech funding crisis than as part of the problem. Yes, we are going strong again, and if you go to page 6, this also is important because in times of short-term volatility, long-term goals and plans are more important than ever. We think that our differentiated platforms, especially PanOmics, will show that the future of Action Plan 2025 is just around the corner, and that many, many goals that are written in this Action Plan 2025 are already achieved, and those who are not achieved yet will be achieved in 25.

Of course, you have to factor in here that Just – Evotec Biologics will come fully online by the end of 2024 and into 2025, as many of the capacities are just in the process of being built. Our business dynamics are looking good. They are also looking good when we make a first view into 2024, where I think again, double-digit growth will be absolutely possible for us in 2024, and that shows you again, the differentiation of our business model versus many other players on the market. With this, let's look a little bit deeper into our Q3 results. With this, I want to hand over to Laetitia.

Laetitia Rouxel (CFO)

Thank you, Werner, and a warm welcome to all of you for joining us today to delve into our financials for the past nine months. Slide 8. As depicted, in this slide, we had very strong start to the year, with revenues in Q1 2023 at EUR 213.6 million, which is an implied growth of 30% versus Q1 2022. A robust underlying base business, as well as new strategic collaboration with Janssen and the expanded collaborations with BMS, have contributed to this excellent performance. In both Q2 and Q3, we confronted the repercussions of the cyber incident, which necessitated a brief shutdown in Q2 to safeguard our partners and stakeholders. This event resulted in missed opportunities of approximately EUR 70 million. Throughout these challenging quarters, our drug discovery and development business were impacted.

Despite these hurdles, we have persevered by expanding our operation and cultivating critical partnerships, like the tech partnership between Just – Evotec Biologics and Sandoz. Our resilience was evident in our financial performance, with Q3 group revenue approaching EUR 200 million and nine months group revenue, which is reaching EUR 580.1 million, reflecting here again an increase of 14% compared to prior year. Moving to the next slide. I will provide here a summary of our selected balance sheet and cash flow details. Between December 31, 2022, and September 30, 2023, total assets decreased slightly by -EUR 2.7 million to EUR 2,254.5 million. There is a shift in the asset composition, reflecting the allocation of cash equivalents towards CapEx investments.

Our stockholders' equity as of September 30, 2023, decreased by EUR 46.4 million to EUR 1,140.8 million, compared to the end of 2022. This change is attributable mainly to the net loss, resulting in an equity ratio of 50.6%, slightly decreased from the 52.6% reported end of last year. We still maintain a strong equity position, ensuring a solid foundation for future investments and maintaining financial flexibility. Operating cash flow in the first nine months was EUR 15.2 million, compared with EUR 236.6 million in the first nine months of last year. The comparable figure last year was driven by a EUR 200 million upfront payment from BMS.

The lower figure this year is impacted by the cyber incident, but it is partially offset by received payments related to our BMS collaboration in neuro and protein degradation. Cash and cash equivalents amounted to EUR 499.4 million as of September 2023. The increase is a result of higher share of our short investments within our group liquidity. Our total liquidity decreased to EUR 613.4 million, as longer-term investments matured and have been used to finance capital expenditures. Capital expenditures amounted to EUR 150 million and were at a similar level than nine months last year, with EUR 157.2 million. The spend in both years was, to a large extent, driven by building our capabilities and capacities for Just – Evotec Biologics, both in the U.S. and in Europe.

Our cash investments in affiliates and associated companies were significantly, significantly reduced to EUR 15.8 million, compared to EUR 70.7 million last year. Moving to the next slide. Group revenues for the first nine months of 2023 demonstrates a robust 14% increase, reaching EUR 580.1 million, fueled by a diverse business portfolio in a challenging environment. Key growth drivers included our BMS Celgene, Celgene programs and the successful delivery of work packages as part of our new technology partnership with Sandoz. Base business kept growing, increasing by 14% from EUR 502.7 million in nine months last year to EUR 575.3 million in the first nine months this year. Evotec received milestones, upfront and licenses payments of EUR 4.8 million....

Just – Evotec Biologics contributed EUR 74.1 million during the 9 months of this year, versus EUR 27.9 million in the comparable prior year period. Here, we've nearly tripled its revenues within 12 months. Switching now our focus to cost management. The cost of revenue for the first 9 months of 2023 amounted to EUR 442.7 million, yielding a gross margin of 23.7%. The increase of margin was supported from signing the collaborations and partnerships with BMS and Sandoz. Excluding effects related to the capacity built, Just – Evotec Biologics, total gross margin would be 26.7%, versus 27.3% during the same period last year. Unpartnered R&D expenses were EUR 45.7 million, 10% lower than the comparable prior year period.

This decrease was influenced by a temporary reduction in R&D costs stemming from the cyber incident. Our Adjusted Group EBITDA, which does not include external one-off cyber-related costs for the nine months ending September 2023, amounted to EUR 50.2 million. Which is the result of missed opportunities after the cyber attack, as well as higher costs to manage adverse effects of the incident. Internal cost of recovery in Q3 2023 were mitigated due to improved cost structures. Therefore, Adjusted EBITDA in Q3 2023 to EUR 16.3 million, versus EUR 11 million in Q3 2022. The nine months 2023 Adjusted EBITDA, excluding Just – Evotec Biologics, would have reached EUR 55.9 million. Moving to slide 11.

Our guidance remain unchanged as previously outlined in our business update in July, with revenue expected in the range of EUR 750 million-790 million. Unpartnered R&D expenses estimated at EUR 60 million-EUR 70 million, and an Adjusted EBITDA targeted of EUR 60 million-EUR 80 million for the full year. Regardless of the treatment of the one-off external cyber cost, we expect EBITDA guidance to be met. Moving slide 12, I would like to share our latest update on our key activities, focusing on cost efficiency and optimization. First, in the pursuit of leaner process across all our sites, we are making great progress. We have focused on optimizing our head count and various cost containment measures, leading to significant savings in 2023.

Early October, Evotec has engaged into the social process of redeploying its chemistry activity out of Marcy-l'Étoile, Lyon, and in parallel, we are gearing up for a focused ERP build-out in the U.K. and at J.POD Toulouse in Europe. From a cash optimization, investment in CapEx have been reprioritized, and we expect EUR 50 million reduction by year-end 2023, as well as reduced equity investments. The good news is that our diligent efforts have not gone unnoticed. We can confirm expected full year savings of EUR 25 million, which is a testament to the effectiveness of our initiative in both cost optimization and efficiency. We will continue to pursue our 2025 strategy for sustainable growth and cost management, remaining dedicated to our shareholders and our overarching mission for medicine that matter. To conclude, we are shaping a more efficient and resilient future where research never stops.

Thank you for your trust and support as we continue this remarkable journey. That said, I will now pass the floor back to you, Werner.

Werner Lanthaler (CEO)

Thank you, Laetitia. If you go to page 14 of this presentation, we want to highlight the paradigm-shifting platforms are our key growth drivers. We are very proud of our end-to-end Shared R&D service platforms. This is the foundation of stability into our long-term growth. This is the foundation of our quality services that we are delivering. But I already mentioned that our differentiated technology platforms are key drivers for our long-term and future success. This comes on top of our end-to-end Shared R&D platforms. And if you look at this graph, you see the big drive that comes from PanOmics and from Just - Evotec Biologics, just to mention two platforms here. And this is why we often say we are just at the beginning of paradigm-shifting platforms that will shape this industry.

If you go to page number 15, we are shaping this industry by pipeline building with PanOmics and other technologies throughout the industry. Please don't forget, it is our long-term goal to build the largest royalty pool in the industry through our partnered R&D model. The numbers that you see on that slide speak for themselves. The EUR 15 billion in milestones are already contracted. The 8%-10% royalties are already contracted. The milestones will come and will provide an important driver for profitability and profitable growth into the future. That's why we are so proud of our partners and the partner pipeline that we are building here. This is enormously efficiently leveraging our R&D platforms into pipeline building efforts.

On page 16, you see that when we're describing our pipeline building efforts, we often use this image of an iceberg, because you only see the top at this stage. On the top, you see 18 projects in the clinic or close to the clinic at this stage. But what you should see, that there are more than 120 projects that are filling that pipeline into the years to come. It's almost irresistible to see more news flow out of this iceberg into the future. If you go to page 17, here are just a few highlights of co-owned or partnered projects where news flow is gonna come, and where the beauty of our business model is that the data point is typically always generated on the costs taken by our partners.

And that's why, for us, this is always a free option to the upside and no downside that comes with the generation of these partnered projects. If you go to page 18 of this presentation, let me jump again to another paradigm-shifting platform, which I already mentioned once today, Just Evotec Biologics. Why do we say paradigm shifting? Because continuous manufacturing will shape a high-cost industry into an affordable industry. Fully continuous manufacturing will create access to so many more people for biologics, that this is something where the term paradigm shifting is clearly well-deserved. And if you look at the two pictures here, maybe it could be a bit better visible, but what is visible here is that on the lower picture, there's nothing. And on the picture on the higher part of this page, there is J.POD 2 existing.

This is not any AI, this is reality in a picture here, where only in 12 months, it is amazing what our people at Evotec do. Let me thank the whole organization for creating such a massive movement, not only in J.PODs, but everywhere on our platforms. If you go to page number 19, making this effort wouldn't make sense if markets wouldn't support us. We couldn't be more excited about the validation that we see for Just – Evotec Biologics, even here in not the easiest times of the overall biotech market. We are finding that our capacity for discovery and development is already very, very well filled, and we are ramping up additional capacity on the basis of future demand, and there are multiple discussions ongoing into 2024 and 2025 already.

So obviously, 25, 24 is excellently filled for Just – Evotec Biologics already, and 25 will be filled through our business development pipeline, which is being built here. Mentioning the number of EUR 850 million contracted sales just gives you comfort here that we have 8 times higher contracted sales than only one year ago. If you go forward in this presentation, and if we jump back to our governance and to our impact that we want to have as a company, let me highlight that it was important, that it's very important, and you see it on page 21, that near-term science-based targets are validated and approved now. Why is this important? Because we always said we want to keep our ESG promises and have aligned our commitment here with our partners to follow the Paris goals.

Like most larger companies, we have now validated science-based targets by SBTi. You will see that this is published on our website as of tomorrow, and it is an important signal that as a company, we want to make a contribution not only to patients, but also to the planet. If you go to page 22, we want to thank the analysts who are recognizing what we are doing here, because a company that gets upgrades by doing more for the planet, I think is also good for every portfolio of an investor to be held. Having here EcoVadis, for example, stepping up in their rating for us, is a good latest signal that we can report. Page 23 is again highlighting the three dimensions on ESG, where we are keeping our promise, the environment, our social impact, and our governance.

On our social impact, we want to make also internally the best of the company every day. So that's why voicing what can be improved is important, and that's why, as of tomorrow, 5,000 people will be part of an EvoVoice, what we call pulse test and engagement survey, to see how we can even better as a company internally, but also towards our partners. If you go to page number 24, let me come to governance, because having the best people around us is key for our long-term success. That's why we are so proud of our existing supervisory board, but we are also so proud that we are permanently able to upgrade our supervisory board with people who have shown that they are shaping the industry with their intellect, with their personality, and also with their business acumen.

We're very proud that Rupert Vessey is suggested to be nominated for membership on our supervisory board and will stand for vote in our next annual general meeting in June 2024. So it's fantastic that Rupert will join this company, and you will see that this is also great for not only Evotec, but also our partner network. Going to page 25, you should see that despite the fact that we had several hiccups this year, we are resilient, and resilience is what you make out of it. And that's why achieving our goals is the plan, and we're executing on our targets, and we are going forward towards action plan 25 and beyond as we speak.

And with this, let me thank you, because 26 shows you and is the invitation to you, not only to come to our next week's Capital Market Day, but also to follow us in the long run into 2024, 2025, and beyond. And page 27 rounds up this presentation again by highlighting that our Capital Markets Day next week will show you how paradigm-shifting technologies like PanOmics and like iPSC-driven drug discovery changes the world, and where you can witness how Evotec is a big part of that. Thank you so much. We are looking forward to your questions.

Operator (participant)

Ladies and gentlemen, at this time, we will begin the question and answer session. Anyone who wishes to ask a question may press star, followed by one on their touchtone telephone. If you wish to remove yourself from the question queue, you may press star followed by two. If you are using speaker equipment today, please lift the handset before making your selections. Anyone who has a question may press star followed by one at this time. One moment for the first question, please. The first question comes from the line of Kirsty Ross-Stewart with Citi. Please go ahead.

Kirsty Ross-Stewart (AVP)

Hi there. Yeah, Kirsty Ross-Stewart from Citi on for Peter Verdult. Two questions from me, please. Firstly, you affirmed your double-digit revenue growth expectations for 2024 in your opening remarks, that the cyber attack this year has obviously depressed 2023 revenues. With that in mind, can you elaborate what is possible with respect to revenue growth for 2024 on a like-for-like basis, i.e., had the cyber attack not happened, and also whether we should expect moderate or strong margin progression in 2024? Just trying to better understand the revenue and EBITDA bridge to your 2025 targets. And then my second question, just ahead of your CMD next week, would you be able to give us a small preview? In particular, what do you specifically want to showcase over and above Just Biologics? Thank you.

Werner Lanthaler (CEO)

So on the CMD preview, I will then hand over to Cord, who will give you a sneak preview into PanOmics, which couldn't be more exciting. I can only say that. And when it comes to our growth into 2024, let me please apologize that we're not giving exact guidance right now, but I think by confirming our 2025 path forward, you should see two things. One, double-digit growth is, for us, possible through paradigm-shifting platforms like PanOmics, where you see, for example, a much higher than 15% growth happening. On our R&D shared platform services, we can see high single-digit and sometimes close to double-digit growth, but this is not going much higher than that because of capacity reasons that we don't want to and cannot build at this stage.

So that's just that you should appreciate the fact that within the portfolio, some things are going much faster in their growth and others are on high single digit. And the areas that go higher in their growth are, of course, where we have high degrees of automation, high degrees of technology, in all the areas where our tech stack is leveraged. When it comes to margin expansion, that will be and should be visible because the goal is, of course, high profitable growth within Evotec and not just growth. So without also giving guidance here, you will clearly see a higher growth in profitability than on the top line in 2024, and I hope that gives you a bit of color. With this, I hand over to Kurt on a sneak preview to the CMD.

Cord Dohrmann (Chief Scientific Officer)

Yeah, hello, everybody. Good morning and good afternoon. We will, what we will intend to do next week during our Capital Markets Day, is to give you a little bit of an insight, how Evotec is positioning itself in the area of precision medicine, which is, predominantly through our efforts in PanOmics. PanOmics is essentially our way of incorporating, Omics technologies, into the drug discovery process from the very beginning, to all the way into the clinic and potentially even the market area in terms of biomarkers, developing another biomarkers.

We will talk about some of the key components of our PanOmics platforms, which includes, for example, our molecular patient databases and how we leverage them into target ID, target selection, but also into the discovery of disease signatures, molecular disease signatures, and patient stratification. We will talk about in particular patient-derived disease models using our iPSC platform. We will also talk about AI machine learning technologies that we incorporate throughout the drug discovery value chain.

Werner Lanthaler (CEO)

Thank you so much. With this, we go to our next question, please.

Operator (participant)

The next question.

Werner Lanthaler (CEO)

Operator, can you see another question? Otherwise, I see that Charles has handed in a question. Maybe we can go to Charles Weston.

Operator (participant)

The next question is from the line of Charles Weston with RBC Capital Markets. Please go ahead.

Werner Lanthaler (CEO)

Great. Hi, Charles. Looks like the line is not opening for Charles. Can we double-check if that's working? Otherwise, let's go to the next question, please. Operator, are you still there?

Operator (participant)

Hello?

Werner Lanthaler (CEO)

Hi, Charles. Here you are.

Charles Weston (Managing Director)

Ah, you can hear me. Oh, great. Well, thank you very much for persevering. One question on the short term and one on the longer term, please. In the short term, the effective guidance, I think, for Q4 is for EBITDA of EUR 10 million-30 million. I'll just keep going over the operator. So it's quite a large range. And I just wanted to understand why it's so large, and whether the change in accounting to remove the cyber attack costs means that the underlying EBITDA expectations may have come down a bit from the last time that you updated the market. I'll ask my second question later, if that's okay.

Werner Lanthaler (CEO)

So no, there is not a come down of our expectations. It's exactly what we wanted to communicate. We have just decided to really give a true and fair view by factoring out what external costs of the cyber attack are. And coming to your wide range, you are absolutely right, of course. But if you follow us over the long time, which you do, you know that milestones are typically happening in the fourth quarter, where many people are finishing up experiments, are handing forward experiments. So that's why individual milestones can come and can influence Q4. Having said that, we have, we are very secure on our guidance, even if there would be a low level of milestones coming in this year, and that's why I think we are with many eyes already in 2024 and are closing out Q4 in a very elegant way this year.

Charles Weston (Managing Director)

Understood. If I can just push you just a little bit on the change, appreciating that removing the external sort of cyber attack related cost is perfectly reasonable to do from an accounting perspective. But it provides an extra EUR 12 million or so of EBITDA for this year. So, you know, and you've kept the guidance the same. So does that mean that you would otherwise have been in the range, but perhaps towards the lower end? Is that what is the signal that you're providing?

Werner Lanthaler (CEO)

I'll give it to Laetitia, but my short comment is, it really is one milestone here and there, and everything is fine. But Laetitia, happy to comment.

Laetitia Rouxel (CFO)

Yes. So as you mentioned, it's important to keep in mind that this adjustment of EUR 11.9 million reflects the fair view of our underlying performance. Regardless of the treatment of this one-off cost, cyber costs, we expect EBITDA guidance to be met. That's, that's no question there. And regarding the EUR 11.9 million, that's the current cost that we have end of September, and of course, we have insurances that will play again in the total year.

Charles Weston (Managing Director)

Okay. All right. Thank you. And then my second question is just on the Sandoz deal. The potential revenues here, which you highlighted when you announced the deal, are very high. But I guess the revenue is going to ramp over time, and there's going to be some costs, potentially coming in ahead of this as you add heads to be able to deliver on that work. Can you help us think about the trajectory of that revenue and EBITDA from this deal over the next few years, please?

Werner Lanthaler (CEO)

Yes. Best is probably to hand over to Matthias for that question because Matthias was also really the man in the middle to create this tech partnership with Sandoz. Maybe you can elaborate.

Matthias Evers (CBO)

Sure. Thanks, Carl for the, Charles, for the question. Good morning, good afternoon, everyone, also from my side. With regards to the Sandoz partnership, we are productively progressing, and no change in guidance and dynamic as we communicated previously. We started working on an accelerated timeline on a number of molecules, and as indicated in one of our last discussions, that the revenues that we indicated of EUR 640 million, I mean, spread over a couple of years, reflecting typical biosimilars timeline, and that we quickly get into the development process for these molecules. So we are indicated at the time, we ramp up over carefully set three years over this period, so we are fully in line and no further change, Charles, at this point of time.

Charles Weston (Managing Director)

Okay, thank you. So, it's around three years for the sort of development process there, and maybe a slightly staggered start over this year and next year in terms of the beginning of the projects?

Matthias Evers (CBO)

So, yes. I mean, let's say 3+, not to be too aggressive here. 3+, somewhat staggered, but that's a model you can work with.

Charles Weston (Managing Director)

Thank you. That's great.

Werner Lanthaler (CEO)

And maybe if I may add one sentence, of course, these are biosimilars, where we think attrition rate will be very low when it comes to the biology of the biologics is really more a question, where do we see the, or where does Sando see the market opportunity? So that will probably then not lead to a full portfolio of all the biosimilars that we are making, but biology attrition rate should be very low.

Charles Weston (Managing Director)

Thank you, Werner.

Werner Lanthaler (CEO)

Pleasure. We go to the next question, and we hope that works a bit better on the operating level now.

Operator (participant)

The next question comes from the line of Philippa Pritchard with Morgan Stanley. Please go ahead.

Philippa Pritchard (Equity Research Analyst)

Hi, there. Thank you for taking my questions. I just have two, please. So the first question is on 2025 guidance for revenue of over EUR 1 billion. How much of this is milestones? What is the probability adjustment, and what extent has biotech funding put some of these milestones at risk, for example, with the recent Exscientia pipeline reprioritization? And secondly, I was wondering if you could provide an update or some color on how the adoption of AI techniques has been across your client base?

For example, what proportion of companies are outsourcing AI efforts now versus using their own internal resources? Where do you expect this to go, and what would the triggers for this shift be? For example, would it be first drug to be approved using AI, technological barriers, et cetera? Any color you could provide on that and what you're seeing, and what your expectations are into the future would be super useful. Thank you.

Werner Lanthaler (CEO)

So on the second question, I would like to highlight again our Capital Markets Day of next week and invite you for that, because that's exactly kind of the discussion that we want to have and that we want to have on a broad basis with you. So that's why maybe for now, it would take too long to really fully answer that, and I'm happy to invite you to a discussion with Matthias, Cord, and Craig to go deeper in this discussion, but again, the invitation to Capital Markets Day for next week. When it comes to our revenue guidance and biotech funding and the milestones that are attributed to that, we at this stage have a range of about EUR 70 million that are, quote, unquote, "The bridge" to that are milestone driven in there.

Having said that, going beyond EUR 1 billion on top line will be clearly possible also without milestones, but achieving our EBITDA is critical to achieve milestones. Yeah, because as you know, milestones have high, high gross margins on them. That's why I think on the top line, we are very comfortable, and on the EBITDA guidance, that's where milestones have to come in and will come in. And that's why highlighting the EUR 15 billion existing contracted milestones is so important, because that's not milestones where we still have to find partners to come to these data points. They are already there. Typically, we don't have large milestones agreement with biotech companies in place.

So if you would go through the EUR 15 billion contracted milestones that we have in place, I would say less than 1% comes from biotech partnerships at this stage, or maybe less than 5% comes from biotech partnerships at this stage. And that's why biotech funding and, for example, programs or companies falling on the wayside through biotech funding does not have an influence on our Royalty Pool Strategy, vision, and plan at all at this stage, because these are typically companies like Novo Nordisk, like Lilly, like BMS, where pipeline building together with us is the name of the game and where milestones are part of that trajectory.

Of course, biotech funding plays a role, if you, if you also want to have a, a sentence on that when it comes to our underlying service, business at this stage, and we have no doubt about that, that the market is softer than what we have seen in the past. But again, we see the offering of Evotec, especially from our Integrated services, as the solution for high-quality data points that are fundable for the venture community and not part of the problem. And especially our Indigo offering sees a lot of demand at this stage. We also see a lot of demand at this stage when it comes to biotech companies that are going for high quality chemistry, that are going for high quality biology. So you see a lot of traction here from biotech companies that are well-funded.

For example, yesterday's announcement from a partnership with Dewpoint is testament that the high-quality biotech companies continue to use our service and even increase that. I hope that gives you a bit of a color. And on the AI question, I apologize, but I don't want to spoil the Capital Markets Day.

Philippa Pritchard (Equity Research Analyst)

That's absolutely fine. Thank you very much.

Werner Lanthaler (CEO)

Pleasure.

Operator (participant)

The next question-

Werner Lanthaler (CEO)

Next question, please.

Operator (participant)

The next question comes from the line of Michael Ryskin with Bank of America. Please go ahead.

Michael Ryskin (Managing Director)

Great. Thanks for taking the question. Can you hear me?

Werner Lanthaler (CEO)

Yes.

Michael Ryskin (Managing Director)

Okay, wonderful. So I've got two, and I'll maybe I'll throw them. I'll do the first one first. So first I want to touch on the, you know, the updated guide or sort of the maintained guide for fiscal year 2023, in light of your third quarter performance. So if my numbers are correct, it implies a little bit of a step down from 3Q to 4Q. I think the guide is at the midpoint, something like EUR 190 million, in the fourth quarter. So I'm just wondering if you could talk about that a little bit more. I know there was always going to be some catch up following the cyber attack. I think you talked about EUR 30 million catch-up.

So was all of that already captured in the third quarter, and so therefore, we should sort of think of that number and that pacing? Just because if it looks, you know, if we look at it as is, the fourth quarter implies a pretty meaningful step down year-over-year and certainly sequentially. So just wondering what the drivers of that are?

Werner Lanthaler (CEO)

So if so, step down is clearly not what you will see in Q4. I think maybe we are a bit cautious here, and cautiousness comes especially throughout our development business. Because the development business, which quote-unquote "is somewhere between EUR 150 million and EUR 200 million total capacity," is the latest that was going fully online after the cyber attack. And we, we were basically not able to contract any business into the summer because we didn't know when to go fully online again. And how this then translates into work completed and revenues recognized is probably behind the quote-unquote "visible" step down here. If it then is in our actual visible like that, I cannot fully guide you to that.

I think the development business is the key driver behind that, and that's due to the fact that up to mid-September, we were not fully sure when to fully start contracting business into development again. I hope that gives you color.

Michael Ryskin (Managing Director)

Okay. Yep, that's helpful. And then somewhat related to that, you know, I thought the, the pie chart visualization you had, I think on, on slide 14, was really helpful, you know, illustrating the growth, from PanOmics and from Just, which is doing really well, obviously. But I also want to focus on, just the Evotec segment, excluding Just. Obviously, that's been a little bit more challenged. I think I imagine that's where a lot of the, you know, one-time impact of the cyber attack is. But even if you back that in, it's still, you know, roughly flat year-over-year. So I, I'm guessing that's where some of the, you know, one, the development work you're talking about now is taking place. Two, that's where some of the market weakness and choppiness you talked about from biotech is going on.

I'm just wondering if you could talk about that a little bit more, sort of the business other than Just – Evotec Biologics and other than PanOmics. What are you seeing there, and when do you think that can return to more consistent growth? Thanks.

Werner Lanthaler (CEO)

Yes. Maybe, maybe on the second part of the question, I hand over first to Craig, who can give you really an operational view of where we are, and second, to Matthias, who is out in our business development lines, that you have also here, better visibility. So maybe Craig first and Matthias second.

Craig Johnstone (COO)

Yeah, thanks. Thanks, Werner. Thanks, Michael, for the question. So in terms of the pie chart, your interpretation is right and your conclusion that that would be where the main one-time hit of cyber attack is felt at its most heavy, if you like. So, and there are two reasons, there are two elements to it. So first of all, on the cost side, of course, the Evotec segment, as we report it, carries the vast majority of the fixed costs of the group, the buildings, the people, the infrastructure, and so on. And being unable to transact on that for some weeks, of course, has a negative impact. And on the revenue side - and I should say, of course, because it's fixed costs, you can't easily adjust them in short term.

On the revenue side, even within what we call our base business, there are variable impacts at the point of sale. So, some aspects of our business and the base business are multi-year, long-standing FTE-based contracts. And of course, those kind of contracts are quite resilient to the negative effects of being unable to do transactional work. But, there are other aspects of our business mix, which are in shorter cycles, such as Cyprotex and indeed, some aspects of the development business, as Werner said, where the cycles are measured in either days or weeks or months. And of course, those areas suffer very sharp deteriorations due to the cyber attack, and it's very hard to fully catch up.

But to finish on where we are now, of course, since Q3, operations have been fully back to full service, albeit with some remaining drag in productivity due to sort of complexity of data handling while we come fully out of the details of cyber. So hopefully that gives you a perspective on the operational side of the question. Matthias?

Michael Ryskin (Managing Director)

Thanks so much.

Matthias Evers (CBO)

Yeah.

Werner Lanthaler (CEO)

Yep.

Matthias Evers (CBO)

Thank you, and thanks for the question to allow us a little bit to talk about the underlying market dynamics. Broadly, I mean, we show significant growth in a demanding market. The demanding market, I would describe as we have seen a shift from what has been perhaps a bit more, a Seller’s market to a Buyer’s market. Where we see, of course, if you look at our portfolio of partnerships with big pharma, mid-size pharma, and biotech, that on the biotech side, we have seen a muted demand given the, low number of Series A, Series B funding. We definitely see that. And we have seen some budget tightening on the pharma side. So that's why I think the market dynamics, have shifted.

However, it's strong—I would strongly note that the unmet needs all the way to the patient, but also the need in departments for innovation remains very high. So we see a series of very attractive partnerships that are constructed not only by us, by others. So that's why we would carefully tie that, the Buyer’s market dynamics, but buyers are out there. So one level down into the various types of businesses, as Werner has said earlier, and you have seen in the presentation, we see strong growth on the high technology-driven, PanOmics-driven type of partnerships. And then we see a spread of dynamics, I mean, in Evotec. Some areas that are more commoditized and maybe more available, have more pressure, whereas we see very good positioning.

So we have a spread of demand, but overall, we see a strong positioning of our services. And maybe to iterate what Werner said on the development side, I think you will have noted that we just a couple of days ago, actually, just yesterday, we announced a partnership with Dewpoint Therapeutics, which is just a prime point on the value of this development platform for all the companies that want to accelerate towards IND, and there are plenty. But then, of course, there are certain services that are much more commoditized. And we have, of course, also seen how some of our CROs reduced their forecast very recently. So bottom line, more buyers market, stronger position of the buyers. We are adjusting, of course, our strategies, but we see healthy demand and as a foundation for our growth.

Werner Lanthaler (CEO)

Laetitia, maybe an additional comment here?

Laetitia Rouxel (CFO)

To come into the financials and to answer to your questions on the revenue evolution, end of September versus last year, we are still showing a revenue growth of 5%, this year, end of September being at EUR 380 million, and last year was EUR 363 million. So we see here exactly what Matthias explained before, that the market dynamic is under pressure, but we are adding good progress and good long-term projects that fill our pipeline in the short term already.

Werner Lanthaler (CEO)

Great. I hope this gives you color from multiple angles. With this, we go to the next question.

Operator (participant)

The next question comes from the line of Steven Mah with TD Cowen. Please go ahead.

Steven Mah (Senior Equity Research Analyst, Life Science & Diagnostic Tools)

Great. I have two questions, one on the cyber attack and one on just biologics. On the cyber attack, I remember you guys had a filing where you indicated there were some potential unknowns which could impact costs in the future. Can you give us a sense for any potential additional costs related to the cyber attack, or is that completely resolved? And then the second question on just biologics, and apologies if you discussed it already. I was having technical difficulties. Had to dial back in... but on just biologics, given the pipeline momentum, what are your thoughts for multiple J.PODs beyond Toulouse, or do you guys have enough capacity with Redmond and Toulouse? Thank you.

Werner Lanthaler (CEO)

So on cyber attack and unknowns, I would say we are really looking at the cyber attack as something in the rear mirror and have identified all topics, are cleaning up all topics, and that's why I wouldn't say that there are any unknowns open and left. And we have started also to give cost dimensions behind it. So I would really take that out of the equation as an unknown and park that. On Just – Evotec Biologics, I probably first hand over to Matthias again.

Matthias Evers (CBO)

Yeah, I mean, thank you. I mean, at this moment of time, we have not planned for any J.POD beyond J.POD 2. That's a short answer. Maybe, to expand a little bit, because, I think your observation—I mean, I agree with your observation, and we feel we see significant momentum on the basis of the validation we have now seen through recent years from the biotech side, on the biosimilar side, on the public, with the Department of Defense on the public side. We are now, ramping up capacity feeding into the J.PODs, also on the process development side. We are in multiple discussions with, with Big Pharma also in terms of really exploring the full potential of this technology.

There will come a point to have that decision, but it's too early, so nothing to report beyond J.POD 2, as we schedule for opening later next year.

Werner Lanthaler (CEO)

Maybe let me highlight one feature out of our Sandoz tech partnership. That, for example, Sandoz bought the option to potentially have access to the technology in their own S-POD, so to say. And that's also something where we are at this stage, exploring future ideas of where could the technology stack go and how could it go. What I think would be clearly a capital inefficient way of using this amazing technology is to build everything on our own. We really want to leverage this as well and as high as possible into the future. I hope that gives you enough color, and by the way, great to hear you and regards to the U.S. And next question, please.

Operator (participant)

The next question comes, is a follow-up question from Charles Weston with RBC Capital Markets. Please go ahead.

Charles Weston (Managing Director)

Thanks for taking my follow-up. It's on capacity and capacity utilization. I can see that you've only increased your headcount by about 2% this year. Obviously, you've had all sorts of issues to deal with. You've also talked about some cost mitigation efforts and delivering improved operating leverage. But can I just talk about capacity? Historically, that might have been, you know, very much related to number of people. How are you thinking about your capacity, capacity utilization using the current number of people that you have and efforts to improve productivity? So should we expect a, you know, an uplift, a material uplift in number of people next year, for example, to be able to deliver 2025 revenues?

Werner Lanthaler (CEO)

So just to highlight one area here, we are, and I have an exact number here, more than 200 open positions that we are at this stage trying to hire for our operations to execute on Just – Evotec Biologics alone in the US and in Europe. So, and that gives you one message first, that we look for the best people and not only for a quantity of people to deliver on our operations. The second thing is, yes, we have slowed down, hiring, especially in the areas where we have commoditized, competition also in, in our fields that we see upcoming. And we are really focusing on where can we leverage technology automatization with high quality people to do that. So that's why the number of headcount shouldn't be the only, factor to see here, how we are leveraging platforms and technology.

When it comes to capacity, also here, it's a, it's a mixed, mixed picture throughout the whole portfolio. For example, that we are putting capacities together where we have subcritical sites. That's a very clear goal also for our long-term value protection plan and efficiency plan, but that's, I think, what every decent business has to do. And when it comes to hiring of next year, I don't have the full numbers here, but you will definitely see that we will look for more than 300-400 people in the whole platform, and that shows you that there will be a close to 10% uplift in people capacity, but a higher than 10% uplift in revenues, and that's exactly, I think, the metrics that we want to build here. Happy to go deeper into, into this?

Charles Weston (Managing Director)

Well, is it just a question on the 200 open positions for biologics? Obviously, some of them are quite specialized. Are you confident you'll be able to find the people to be able to deliver on that uplift in work?

Werner Lanthaler (CEO)

Yes, absolutely, because people love fully continuous technologies and love to be part of that paradigm shifting situation in the industry. And you wouldn't believe it, how people really stand there with stars in their eyes when they say, "Finally!"... I can now go to the high tech that I always wanted to be part of, and that's part of the attraction. So that's why we are very confident in doing that. Last sentence on, on that, maybe to Matthias?

Matthias Evers (CBO)

No, and be assured, we have a very tight process in place. We have, I think, a complete process underway on the recruiting side to tap into the talent pool. And also to be clear, the input, the roles exist in the industry. So that's why I think the love for the paradigm shift really plays out. So we are not looking for a new or unique breed of talent.

Werner Lanthaler (CEO)

Great. I want to be mindful of all your time, and I know that many of you have a sharp stop at 4 P.M. or 3 P.M., wherever time zone you are. So that's why, please, all further questions, direct them to Volker or direct them to us directly. We are more than happy to come back to you. And before we close today, let me have a special thanks spelled out, because it's so many people who are making quarterly reportings and to do this, and sometimes you don't even hear them on the speaker. But with us in the room is Holger Scheel, who has been doing quarterlies together with us for more than 15 years now. And Holger will change roles and will then no longer be together with us in making these quarterlies.

Let me thank Holger wholeheartedly for 15 years of perfect quarterlies all together in one room here. Thank you so much, Holger. With this, thank you to all of you, and I hope to see you very soon, and I hope to see many of you in person in Hamburg. Tickets are cheap to Hamburg, and food is excellent in Hamburg, so please come to the Capital Markets Day. All the best.

Operator (participant)

Ladies and gentlemen, thank you for calling. The conference is now concluded.